Searching for up to 100 curated homologs for Pf6N2E2_5444 Phosphoribosylglycinamide formyltransferase 2 (EC 2.1.2.-) (393 a.a.)

Found high-coverage hits (≥70%) to 33 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

PurT / b1849 phosphoribosylglycinamide formyltransferase 2 (EC 2.7.2.15; EC 2.7.2.1) from Escherichia coli K-12 substr. MG1655 (see 10 papers)
PURT_ECOLI / P33221 Formate-dependent phosphoribosylglycinamide formyltransferase; 5'-phosphoribosylglycinamide transformylase 2; Formate-dependent GAR transformylase; GAR transformylase 2; GART 2; GAR transformylase T; Non-folate glycinamide ribonucleotide transformylase; Phosphoribosylglycinamide formyltransferase 2; EC 6.3.1.21 from Escherichia coli (strain K12) (see 6 papers)
purT / P33221 phosphoribosylglycinamide formyltransferase 2 (EC 6.3.1.21; EC 2.7.2.15) from Escherichia coli (strain K12) (see 8 papers)
    68% identity, 100% coverage of query (538 bits)

1eyzA / P33221 Structure of escherichia coli purt-encoded glycinamide ribonucleotide transformylase complexed with mg and amppnp (see paper)
    67% identity, 99% coverage of query (529 bits)

1kjiA Crystal structure of glycinamide ribonucleotide transformylase in complex with mg-amppcp
    67% identity, 99% coverage of query (529 bits)

1ez1A Structure of escherichia coli purt-encoded glycinamide ribonucleotide transformylase complexed with mg, amppnp, and gar
    67% identity, 99% coverage of query (529 bits)

1kjqA Crystal structure of glycinamide ribonucleotide transformylase in complex with mg-adp
    67% identity, 99% coverage of query (525 bits)

1kjjA Crystal structure of glycniamide ribonucleotide transformylase in complex with mg-atp-gamma-s
    67% identity, 99% coverage of query (522 bits)

1kj8A Crystal structure of purt-encoded glycinamide ribonucleotide transformylase in complex with mg-atp and gar
    67% identity, 99% coverage of query (522 bits)

purT / Q58881 phosphoribosylglycinamide formyltransferase monomer (EC 6.3.1.21) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (see paper)
    60% identity, 99% coverage of query (470 bits)

O58056 Formate-dependent phosphoribosylglycinamide formyltransferase; 5'-phosphoribosylglycinamide transformylase 2; Formate-dependent GAR transformylase; GAR transformylase 2; GART 2; Non-folate glycinamide ribonucleotide transformylase; Phosphoribosylglycinamide formyltransferase 2; EC 6.3.1.21 from Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
    50% identity, 99% coverage of query (388 bits)

2dwcB / O58056 Crystal structure of probable phosphoribosylglycinamide formyl transferase from pyrococcus horikoshii ot3 complexed with adp
    48% identity, 99% coverage of query (366 bits)

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Build an alignment for Pf6N2E2_5444 and 10 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

3ax6A / Q9WYS8 Crystal structure of n5-carboxyaminoimidazole ribonucleotide synthetase from thermotoga maritima
    26% identity, 93% coverage of query (126 bits)

3r5hA Crystal structure of adp-air complex of purk: n5-carboxyaminoimidazole ribonucleotide synthetase (see paper)
    28% identity, 94% coverage of query (120 bits)

3v4sA Crystal structure of adp-atp complex of purk: n5-carboxyaminoimidazole ribonucleotide synthetase
    28% identity, 94% coverage of query (120 bits)

3v4sB Crystal structure of adp-atp complex of purk: n5-carboxyaminoimidazole ribonucleotide synthetase
    28% identity, 94% coverage of query (120 bits)

3q2oA Crystal structure of purk: n5-carboxyaminoimidazole ribonucleotide synthetase
    28% identity, 94% coverage of query (120 bits)

4dlkA Crystal structure of atp-ca++ complex of purk: n5- carboxyaminoimidazole ribonucleotide synthetase
    28% identity, 94% coverage of query (120 bits)

Q2QJL2 5-(carboxyamino)imidazole ribonucleotide mutase (EC 5.4.99.18) from Acetobacter aceti (see paper)
purK / AAZ04484.1 N5-carboxyaminoimidazole ribonucleotide synthetase from Acetobacter aceti (see paper)
    28% identity, 80% coverage of query (119 bits)

P15567 phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21) from Schizosaccharomyces pombe (see paper)
ade6 / RF|NP_588141.1 phosphoribosylaminoimidazole carboxylase Ade6; EC 4.1.1.21 from Schizosaccharomyces pombe (see paper)
    26% identity, 92% coverage of query (106 bits)

Q9UVE6 phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21) from Zygosaccharomyces rouxii (see paper)
    28% identity, 89% coverage of query (105 bits)

ADE2 / AAA96380.1 phosphoribosylaminoimidazole carboxylase from Schwanniomyces occidentalis (see paper)
    23% identity, 89% coverage of query (102 bits)

3aw8A / Q5SKY0 Crystal structure of n5-carboxyaminoimidazole ribonucleotide synthetase from thermus thermophilus hb8
    29% identity, 89% coverage of query (101 bits)

AN3626 phosphoribosyl-aminoimidazole carboxylase (AFU_orthologue; AFUA_4G12600) from Emericella nidulans (see paper)
    28% identity, 85% coverage of query (100 bits)

3orqA / A0A0H3KFM7 Crystal structure of n5-carboxyaminoimidazole synthetase from staphylococcus aureus complexed with adp (see paper)
    25% identity, 88% coverage of query (100 bits)

Q92210 phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21) from Candida albicans (see paper)
ADE2 phosphoribosylaminoimadazole carboxylase from Candida albicans (see 8 papers)
    25% identity, 89% coverage of query (100 bits)

Q01930 phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21) from Ogataea methanolica (see paper)
    26% identity, 89% coverage of query (99.4 bits)

3k5hA / A1CII2 Crystal structure of carboxyaminoimidazole ribonucleotide synthase from asperigillus clavatus complexed with atp (see paper)
    28% identity, 85% coverage of query (97.1 bits)

3k5iA Crystal structure of n5-carboxyaminoimidazole synthase from aspergillus clavatus in complex with adp and 5-aminoimadazole ribonucleotide
    28% identity, 85% coverage of query (97.1 bits)

A1CII2 5-(carboxyamino)imidazole ribonucleotide synthase (EC 6.3.4.18) from Aspergillus clavatus (see paper)
    28% identity, 85% coverage of query (96.3 bits)

PUR6_YEAST / P21264 Phosphoribosylaminoimidazole carboxylase; AIR carboxylase; AIRC; EC 4.1.1.21 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
P21264 phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21) from Saccharomyces cerevisiae (see paper)
ADE2 / P21264 phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 3 papers)
    23% identity, 89% coverage of query (94.0 bits)

purK / CAA73603.1 purK from Saccharolobus solfataricus (see paper)
    24% identity, 92% coverage of query (84.0 bits)

PURK_MYCTU / P9WHL9 N5-carboxyaminoimidazole ribonucleotide synthase; N5-CAIR synthase; 5-(carboxyamino)imidazole ribonucleotide synthetase; EC 6.3.4.18 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
    29% identity, 89% coverage of query (71.6 bits)

MCCA_ARATH / Q42523 Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial; MCCase subunit alpha; 3-methylcrotonyl-CoA carboxylase 1; 3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha; EC 6.4.1.4 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Q42523 methylcrotonoyl-CoA carboxylase (EC 6.4.1.4) from Arabidopsis thaliana (see 2 papers)
    23% identity, 78% coverage of query (48.1 bits)

Q9FAF5 biotin carboxylase (EC 6.3.4.14) from Myxococcus xanthus (see paper)
    28% identity, 76% coverage of query (46.2 bits)

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