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Searching for up to 100 curated homologs for PfGW456L13_122 Branched-chain amino acid transport system permease protein LivM (TC 3.A.1.4.1) (427 a.a.)

Found high-coverage hits (≥70%) to 12 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

TC 3.A.1.4.8 / P21628 High-affinity branched-chain amino acid transport system permease protein BraE, component of Branched chain amino acid uptake transporter. Transports alanine from Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
    54% identity, 95% coverage of query (383 bits)

Pf6N2E2_2924 ABC transporter for L-leucine/L-isoleucine/L-phenylalanine/D-alanine, permease component 2 LivM from Pseudomonas fluorescens FW300-N2E2
    53% identity, 97% coverage of query (382 bits)

AZOBR_RS08240 L-proline and D-alanine ABC transporter, permease component 2 from Azospirillum brasilense Sp245
    58% identity, 74% coverage of query (353 bits)

LivM / b3456 branched chain amino acid/phenylalanine ABC transporter membrane subunit LivM (EC 7.4.2.2) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
LivM / P22729 branched chain amino acid/phenylalanine ABC transporter membrane subunit LivM (EC 7.4.2.2) from Escherichia coli (strain K12) (see 5 papers)
LIVM_ECOLI / P22729 High-affinity branched-chain amino acid transport system permease protein LivM; LIV-I protein M from Escherichia coli (strain K12) (see paper)
TC 3.A.1.4.1 / P22729 LivM aka B3456, component of Leucine; leucine/isoleucine/valine porter from Escherichia coli (see 5 papers)
    58% identity, 74% coverage of query (340 bits)

braE / CAB75550.1 integral membrane protein from Rhizobium leguminosarum bv. viciae (see 2 papers)
    54% identity, 72% coverage of query (294 bits)

HSERO_RS00890 L-proline ABC transporter, permease component 2 from Herbaspirillum seropedicae SmR1
    40% identity, 74% coverage of query (221 bits)

Ac3H11_1694 ABC transporter for glutamine/isoleucine/leucine/phenylalanine/proline/serine/tyrosine, permease component 2 from Acidovorax sp. GW101-3H11
    42% identity, 74% coverage of query (194 bits)

TC 3.A.1.4.3 / Q8VM84 BraE aka Bra2E, component of General L- (and D-)amino acid uptake porter (transports acidic, basic, polar, semipolar and hydrophobic amino acids). The amino and carboxyl groups do not need to be α since γ-aminobutyric acid (GABA) is a substrate. The system may function with additional binding proteins since L-alanine uptake is not dependent on BraC from Rhizobium leguminosarum (biovar viciae) (see paper)
    31% identity, 70% coverage of query (123 bits)

Build an alignment

Build an alignment for PfGW456L13_122 and 8 homologs with ≥ 30% identity

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Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Additional hits (identity < 30%)

TC 3.A.1.4.11 / Q6N8W1 Putative branched-chain amino acid transport system ATP-binding protein, component of The phenylpropeneoid uptake porter, CouPSTW from Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009)
    28% identity, 74% coverage of query (99.8 bits)

TC 3.A.1.4.4 / Q9L3S4 UrtC, component of The high-affinity (<1 μM) urea porter (see paper)
    23% identity, 75% coverage of query (66.2 bits)

TC 3.A.1.4.5 / Q8NRV9 UrtC, component of The high affinity urea/thiourea/hydroxyurea porter from Corynebacterium glutamicum (see paper)
    27% identity, 70% coverage of query (63.2 bits)

LivH / b3457 branched chain amino acid/phenylalanine ABC transporter membrane subunit LivH (EC 7.4.2.2) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
LivH / P0AEX7 branched chain amino acid/phenylalanine ABC transporter membrane subunit LivH (EC 7.4.2.2) from Escherichia coli (strain K12) (see 4 papers)
TC 3.A.1.4.1 / P0AEX7 High-affinity branched-chain amino acid transport system permease protein LivH aka B3457, component of Leucine; leucine/isoleucine/valine porter from Escherichia coli (see 6 papers)
livH high-affinity branched-chain amino acid ABC transporter, permease protein LivH from Escherichia coli K12 (see 6 papers)
    27% identity, 71% coverage of query (52.0 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory