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Searching for up to 100 curated homologs for PfGW456L13_146 FitnessBrowser__pseudo13_GW456_L13:PfGW456L13_146 (521 a.a.)

Found high-coverage hits (≥70%) to 7 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

TC 3.A.1.10.3 / P71338 FbpB, component of Ferric iron (Fe3+) porter, FbpABC or HitABC (selective for trivalent cations, Fe3+, Ga3+ and Al3+) from Haemophilus influenzae (see 2 papers)
    45% identity, 95% coverage of query (394 bits)

TC 3.A.1.10.5 / Q56926 YfuB protein, component of Siderophore-independent iron uptake system, AfuABC from Yersinia enterocolitica (type O:8)
yfuB / CAA87395.1 YfuB protein from Yersinia enterocolitica (see paper)
    41% identity, 96% coverage of query (304 bits)

TC 3.A.1.10.1 / P21409 SfuB aka FBPB, component of Ferric iron (Fe3+) porter, SfuABC (Angerer et al. 1990). These iron uptake systems have been reviewed (Angerer et al. 1992). Delepelaire 2019 reviewed structural and functional aspects of iron ABC transporters with emphasis on their substrate binding proteins from Serratia marcescens (see paper)
    42% identity, 97% coverage of query (300 bits)

TC 3.A.1.10.2 / Q55534 FutB aka HITB aka SLR0327, component of Ferric iron (Fe3+) porter (see paper)
    30% identity, 95% coverage of query (166 bits)

Build an alignment

Build an alignment for PfGW456L13_146 and 4 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

TC 3.A.1.10.4 / Q82VN6 Iron transport system permease protein, component of The Fe-hydroxamate-type siderophore uptake porter (transports Fe+3 bound to ferrioxamine, ferrichrome or pyoverdine siderophores) from Nitrosomonas europaea (see paper)
    29% identity, 86% coverage of query (148 bits)

TC 3.A.1.20.3 / A3N295 Ferric transport system permease protein fbpB, component of Iron (Fe3+) uptake porter, AfuABC (FbpABC) (Chin et al. 1996). AfuA has been characterized from Actinobacillus pleuropneumoniae serotype 5b (strain L20)
    23% identity, 87% coverage of query (86.3 bits)

TC 3.A.1.20.2 / Q9KLQ6 Iron(III) ABC transporter, permease protein, component of Hexose-phosphate transporter from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
    24% identity, 90% coverage of query (82.8 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory