Searching for up to 100 curated homologs for PfGW456L13_2401 FitnessBrowser__pseudo13_GW456_L13:PfGW456L13_2401 (267 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
DkgB / b0207 methylglyoxal reductase DkgB (EC 1.1.1.91; EC 1.1.1.346) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
dkgB / P30863 methylglyoxal reductase DkgB (EC 1.1.1.21; EC 1.1.1.91; EC 1.1.1.346) from Escherichia coli (strain K12) (see 5 papers)
dkgB / MB|P30863 2,5-diketo-D-gluconic acid reductase B; EC 1.1.1.274 from Escherichia coli K12 (see 5 papers)
70% identity, 100% coverage of query (380 bits)
A0QV10 Aldo-keto reductase MSMEG_2408/MSMEI_2347; EC 1.1.1.- from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis)
40% identity, 96% coverage of query (176 bits)
DkgA / b3012 methylglyoxal reductase DkgA (EC 1.1.1.346) from Escherichia coli K-12 substr. MG1655 (see 10 papers)
dkgA / Q46857 methylglyoxal reductase DkgA (EC 1.1.1.21; EC 1.1.1.346) from Escherichia coli (strain K12) (see 9 papers)
Q46857 2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming) (EC 1.1.1.346) from Escherichia coli (see paper)
38% identity, 95% coverage of query (174 bits)
AKR_SYNY3 / P74308 Aldo/keto reductase slr0942; AKR; AKR3G1; EC 1.1.1.184 from Synechocystis sp. (strain PCC 6803 / Kazusa) (see 2 papers)
40% identity, 96% coverage of query (169 bits)
A6PR / P28475 aldose-6-phosphate reductase subunit (EC 1.1.1.200) from Malus domestica (see 2 papers)
P28475 aldose-6-phosphate reductase (NADPH) (EC 1.1.1.200) from Malus domestica (see paper)
34% identity, 96% coverage of query (169 bits)
ALDR_ENCCU / Q8SSK6 Aldose reductase; AR; Aldehyde reductase; EC 1.1.1.21 from Encephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite) (see paper)
38% identity, 98% coverage of query (169 bits)
7s5fB / A0A1U9WT24 Crystal structure of mannose-6-phosphate reductase from celery (apium graveolens) leaves with NADP+ and mannonic acid bound (see paper)
34% identity, 97% coverage of query (169 bits)
H9CWC0 2,5-didehydrogluconate reductase (2-dehydro-D-gluconate-forming) (EC 1.1.1.274) from Corynebacterium glutamicum (see paper)
39% identity, 95% coverage of query (168 bits)
Y2996_MYCBO / Q7TXI6 Aldo-keto reductase BQ2027_MB2996; EC 1.1.1.- from Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) (see paper)
39% identity, 96% coverage of query (168 bits)
Y2971_MYCTU / P9WQA5 Aldo-keto reductase Rv2971; AKR; EC 1.1.1.- from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 3 papers)
39% identity, 96% coverage of query (168 bits)
M6PR / P92923 mannose 6-phosphate reductase (EC 1.1.1.224) from Apium graveolens (see paper)
P92923 mannose-6-phosphate 6-reductase (EC 1.1.1.224) from Apium graveolens (see paper)
33% identity, 97% coverage of query (167 bits)
GCY1_YEAST / P14065 Glycerol 2-dehydrogenase (NADP(+)); Galactose-inducible crystallin-like protein 1; EC 1.1.1.156 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 13 papers)
34% identity, 99% coverage of query (166 bits)
4gieA / Q4DJ07 Crystal structure of prostaglandin f synthase from trypanosoma cruzi bound to NADP (see paper)
34% identity, 99% coverage of query (164 bits)
Q4DJ07 prostaglandin-F synthase (EC 1.1.1.188) from Trypanosoma cruzi (see paper)
34% identity, 99% coverage of query (164 bits)
4fziA Crystal structure of prostaglandin f synthase from trypanosoma cruzi
34% identity, 99% coverage of query (164 bits)
2bgsA / P23901 Holo aldose reductase from barley (see paper)
35% identity, 96% coverage of query (163 bits)
AR-h / CAA88322.1 aldose reductase from Hordeum vulgare (see paper)
35% identity, 96% coverage of query (163 bits)
PGFS_TRYBB / Q9GV41 9,11-endoperoxide prostaglandin H2 reductase; Prostaglandin F2-alpha synthase; EC 1.1.1.- from Trypanosoma brucei brucei (see paper)
35% identity, 95% coverage of query (163 bits)
dkgA / P06632 2,5-diketo-D-gluconate reductase A monomer (EC 1.1.1.346) from Corynebacterium sp. (strain ATCC 31090) (see 4 papers)
DKGA_CORSC / P06632 2,5-diketo-D-gluconic acid reductase A; 2,5-DKG reductase A; 2,5-DKGR A; 25DKGR-A; AKR5C; EC 1.1.1.346 from Corynebacterium sp. (strain ATCC 31090) (see 2 papers)
P06632 2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming) (EC 1.1.1.346) from Corynebacterium sp. (see paper)
42% identity, 94% coverage of query (163 bits)
2vdgA Barley aldose reductase 1 complex with butanol
35% identity, 96% coverage of query (163 bits)
1vbjA / Q9GV41 The crystal structure of prostaglandin f synthase from trypanosoma brucei
35% identity, 95% coverage of query (162 bits)
1a80A / P06632 Native 2,5-diketo-d-gluconic acid reductase a from corynbacterium sp. Complexed with NADPH (see paper)
42% identity, 94% coverage of query (162 bits)
1m9hA Corynebacterium 2,5-dkgr a and phe 22 replaced with tyr (f22y), lys 232 replaced with gly (k232g), arg 238 replaced with his (r238h)and ala 272 replaced with gly (a272g)in presence of nadh cofactor
42% identity, 94% coverage of query (162 bits)
1vp5A / Q9X0A2 Crystal structure of 2,5-diketo-d-gluconic acid reductase (tm1009) from thermotoga maritima at 2.40 a resolution
38% identity, 95% coverage of query (161 bits)
AKR4C9 / Q0PGJ6 aldo-keto reductase family 4 member C9 (EC 1.1.1.21; EC 1.1.1.210; EC 1.1.1.2; EC 1.1.1.54) from Arabidopsis thaliana (see 2 papers)
AKRC9_ARATH / Q0PGJ6 NADPH-dependent aldo-keto reductase, chloroplastic; AtChlAKR; Aldo-keto reductase family 4 member C9; EC 1.1.1.- from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
33% identity, 96% coverage of query (161 bits)
3h7uA / Q0PGJ6 Crystal structure of the plant stress-response enzyme akr4c9 (see paper)
33% identity, 96% coverage of query (160 bits)
Q7SD67 L-xylulose reductase (EC 1.1.1.10); D-xylose reductase (EC 1.1.1.307) from Neurospora crassa (see 2 papers)
33% identity, 97% coverage of query (160 bits)
xyrB / A2QQ97 D-xylose reductase XyrB (EC 1.1.1.21; EC 1.1.1.431) from Aspergillus niger (strain ATCC MYA-4892 / CBS 513.88 / FGSC A1513) (see 4 papers)
38% identity, 90% coverage of query (159 bits)
Q5FT75 carbonyl reductase (NADPH) (EC 1.1.1.184) from Gluconobacter oxydans (see paper)
38% identity, 94% coverage of query (158 bits)
3wbwA / Q5FT75 Crystal structure of gox0644 in complex with NADPH
38% identity, 94% coverage of query (158 bits)
A2T1W7 aldose reductase (EC 1.1.1.21) from Zea mays (see 2 papers)
35% identity, 97% coverage of query (157 bits)
yvgN / O32210 glyoxal/methylglyoxal reductase (EC 1.1.1.283; EC 1.1.1.91) from Bacillus subtilis (strain 168) (see 3 papers)
GR_BACSU / O32210 Glyoxal reductase; GR; Methylglyoxal reductase; EC 1.1.1.-; EC 1.1.1.283 from Bacillus subtilis (strain 168) (see paper)
37% identity, 100% coverage of query (157 bits)
3d3fA / O32210 Crystal structure of yvgn and cofactor NADPH from bacillus subtilis (see paper)
37% identity, 100% coverage of query (157 bits)
3krbA / A8BGX6 Structure of aldose reductase from giardia lamblia at 1.75a resolution (see paper)
34% identity, 95% coverage of query (155 bits)
YPR1_YEAST / Q12458 Putative reductase 1; EC 1.1.1.- from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
35% identity, 95% coverage of query (155 bits)
5jh2A / A2T1W7 Crystal structure of the holo form of akr4c7 from maize (see paper)
36% identity, 94% coverage of query (154 bits)
E3W861 carbonyl reductase (NADPH) (EC 1.1.1.184) from Bacillus sp. (in: Bacteria) (see paper)
3b3dA / O34678 B.Subtilis ytbe (see paper)
37% identity, 96% coverage of query (154 bits)
G0SCE7 D-xylose reductase (EC 1.1.1.307) from Chaetomium thermophilum (see paper)
33% identity, 98% coverage of query (153 bits)
ALDX_SPOSA / P27800 Aldehyde reductase 1; ALR 1; Alcohol dehydrogenase [NADP(+)]; Aldehyde reductase I; EC 1.1.1.2 from Sporidiobolus salmonicolor (Yeast-like fungus) (Sporobolomyces salmonicolor) (see 2 papers)
AAB17362.1 NADPH-dependent aldehyde reductase from Sporidiobolus salmonicolor (see paper)
33% identity, 100% coverage of query (153 bits)
larA / A2QBD7 L-arabinose reductase LarA (EC 1.1.1.431; EC 1.1.1.21) from Aspergillus niger (strain ATCC MYA-4892 / CBS 513.88 / FGSC A1513) (see 5 papers)
34% identity, 97% coverage of query (152 bits)
BN592_00768 / R7AF73 NAD(P)-dependent bile acid 3β-dehydrogenase (EC 1.1.1.391) from Eggerthella sp. CAG:298 (see 2 papers)
R7AF73 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific) (EC 1.1.1.213); 3beta-hydroxysteroid 3-dehydrogenase (EC 1.1.1.270) from Eggerthella sp. CAG:298 (see paper)
34% identity, 93% coverage of query (152 bits)
4g5dA / P22045 X-ray crystal structure of prostaglandin f synthase from leishmania major friedlin bound to NADPH (see paper)
34% identity, 96% coverage of query (152 bits)
PGFS_LEIMA / P22045 9,11-endoperoxide prostaglandin H2 reductase; Prostaglandin F2-alpha synthase; EC 1.1.1.- from Leishmania major (see paper)
P22045 prostaglandin-F synthase (EC 1.1.1.188) from Leishmania major (see paper)
34% identity, 96% coverage of query (152 bits)
A0A3P3ZE14 prostaglandin-F synthase (EC 1.1.1.188) from Leishmania braziliensis (see paper)
34% identity, 96% coverage of query (152 bits)
7f7kB / A0A5J6VLZ7 Crystal structure of akr4c17 bound with NADP+
37% identity, 97% coverage of query (151 bits)
2wzmA / A0QV09 Crystal structure of a mycobacterium aldo-keto reductase in its apo and liganded form (see paper)
38% identity, 96% coverage of query (151 bits)
7f7mA Akr4c17 in complex with NADP+ and glyphosate
37% identity, 97% coverage of query (151 bits)
7f7lA Crystal structure of akr4c17 bound with NADPH
37% identity, 97% coverage of query (151 bits)
Y2407_MYCS2 / A0QV09 Aldo-keto reductase MSMEG_2407/MSMEI_2346; AKR; AKR5H1; EC 1.1.1.- from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see paper)
38% identity, 96% coverage of query (150 bits)
GCY1 putative uncharacterized protein from Candida albicans (see paper)
37% identity, 93% coverage of query (150 bits)
Q9X265 carbonyl reductase (NADPH) (EC 1.1.1.184) from Thermotoga maritima (see 2 papers)
37% identity, 93% coverage of query (150 bits)
6kikA / Q9X265 Crystal structure of a thermostable aldo-keto reductase tm1743 in complex with inhibitor tolrestat (see paper)
37% identity, 93% coverage of query (150 bits)
5danA Crystal structure of a novel aldo keto reductase tm1743 from thermotoga maritima in complex with NADP+
37% identity, 93% coverage of query (150 bits)
6kiyA Crystal structure of a thermostable aldo-keto reductase tm1743 in complex with inhibitor epalrestat
37% identity, 93% coverage of query (150 bits)
5y7nA Crystal structure of akr1b10 in complex with NADP+ and androst-4-ene- 3-beta-6-alpha-diol
32% identity, 96% coverage of query (150 bits)
AK1BA_HUMAN / O60218 Aldo-keto reductase family 1 member B10; ARL-1; Aldose reductase-like; Aldose reductase-related protein; ARP; hARP; Small intestine reductase; SI reductase; EC 1.1.1.300; EC 1.1.1.54 from Homo sapiens (Human) (see 7 papers)
O60218 aldose reductase (EC 1.1.1.21) from Homo sapiens (see 2 papers)
32% identity, 96% coverage of query (149 bits)
4gq0A / O60218 Crystal structure of akr1b10 complexed with NADP+ and caffeic acid phenethyl ester
32% identity, 96% coverage of query (149 bits)
XYL1_PYRO7 / G4N708 NAD(P)H-dependent D-xylose reductase XYR1; XR; EC 1.1.1.307 from Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) (Rice blast fungus) (Magnaporthe oryzae) (see paper)
32% identity, 97% coverage of query (149 bits)
GRE3 putative uncharacterized protein GRE3 from Candida albicans (see paper)
34% identity, 99% coverage of query (149 bits)
4gabA Human akr1b10 mutant v301l complexed with NADP+ and fidarestat
32% identity, 95% coverage of query (149 bits)
4ga8A Human akr1b10 mutant v301l complexed with NADP+ and sorbinil
32% identity, 95% coverage of query (149 bits)
4i5xA Crystal structure of akr1b10 complexed with NADP+ and flufenamic acid
32% identity, 96% coverage of query (149 bits)
1zuaX Crystal structure of akr1b10 complexed with NADP+ and tolrestat
32% identity, 96% coverage of query (149 bits)
4jiiX Crystal structure of akr1b10 complexed with NADP+ and zopolrestat
32% identity, 96% coverage of query (149 bits)
4jihA Crystal structure of akr1b10 complexed with NADP+ and epalrestat
32% identity, 96% coverage of query (149 bits)
5m2fX Crystal structure of human akr1b10 complexed with NADP+ and the synthetic retinoid uvi2008
32% identity, 95% coverage of query (149 bits)
5liyX Crystal structure of human akr1b10 complexed with NADP+ and the inhibitor mk204
32% identity, 95% coverage of query (149 bits)
5lixX Crystal structure of human akr1b10 complexed with NADP+ and the inhibitor mk184
32% identity, 95% coverage of query (149 bits)
5liwX Crystal structure of human akr1b10 complexed with NADP+ and the inhibitor mk319
32% identity, 95% coverage of query (149 bits)
5liuX Crystal structure of human akr1b10 complexed with NADP+ and the inhibitor idd388
32% identity, 95% coverage of query (149 bits)
5likX Crystal structure of human akr1b10 complexed with NADP+ and the inhibitor mk181
32% identity, 95% coverage of query (149 bits)
4xzlX Crystal structure of human akr1b10 complexed with NADP+ and jf0049
32% identity, 95% coverage of query (149 bits)
4wevX Crystal structure of human akr1b10 complexed with NADP+ and sulindac
32% identity, 95% coverage of query (149 bits)
4iccX Crystal structure of human akr1b10 complexed with NADP+ and jf0064
32% identity, 95% coverage of query (149 bits)
5uxfA Crystal structure of mouse recon (akr1c13) in complex with cyclic di- amp
31% identity, 95% coverage of query (149 bits)
AKR1E2 / P82125 1,5-anhydro-D-fructose reductase (EC 1.1.1.263) from Sus scrofa (see paper)
AKCL2_PIG / P82125 1,5-anhydro-D-fructose reductase; AF reductase; Aldo-keto reductase family 1 member C-like protein 2; Aldo-keto reductase family 1 member CL2; Aldo-keto reductase family 1 member E2; EC 1.1.1.263 from Sus scrofa (Pig) (see paper)
33% identity, 96% coverage of query (148 bits)
akr5f1 organophosphate reductase from Klebsiella sp. F51-1-2 (see paper)
35% identity, 94% coverage of query (147 bits)
3h7rA / O80944 Crystal structure of the plant stress-response enzyme akr4c8 (see paper)
35% identity, 90% coverage of query (147 bits)
AKR4C8 / O80944 aldo-keto reductase family 4 member C8 (EC 1.1.1.21; EC 1.1.1.210) from Arabidopsis thaliana (see paper)
AKRC8_ARATH / O80944 Aldo-keto reductase family 4 member C8; EC 1.1.1.- from Arabidopsis thaliana (Mouse-ear cress) (see paper)
35% identity, 90% coverage of query (147 bits)
S4WCW2 D-xylose reductase (EC 1.1.1.307) from Spathaspora passalidarum (see paper)
34% identity, 96% coverage of query (147 bits)
AKR1A1 / P50578 aldehyde reductase (EC 1.1.1.2) from Sus scrofa (see paper)
AK1A1_PIG / P50578 Aldo-keto reductase family 1 member A1; Alcohol dehydrogenase [NADP(+)]; Aldehyde reductase; Glucuronate reductase; Glucuronolactone reductase; EC 1.1.1.2; EC 1.1.1.372; EC 1.1.1.54; EC 1.1.1.19; EC 1.1.1.20 from Sus scrofa (Pig) (see paper)
P50578 alcohol dehydrogenase (NADP+) (EC 1.1.1.2) from Sus scrofa (see 2 papers)
3fx4A / P50578 Porcine aldehyde reductase in ternary complex with inhibitor (see paper)
30% identity, 97% coverage of query (147 bits)
A0A0M4HL56 D-xylose reductase (EC 1.1.1.307) from Debaryomyces nepalensis (see 3 papers)
33% identity, 96% coverage of query (147 bits)
5zcmA / A0A0M4HL56 Crystal structure of xylose reductase from debaryomyces nepalensis in complex with NADP-dtt adduct (see paper)
33% identity, 96% coverage of query (147 bits)
3h4gA Structure of aldehyde reductase holoenzyme in complex with potent aldose reductase inhibitor fidarestat: implications for inhibitor binding and selectivity
30% identity, 97% coverage of query (147 bits)
3cv7A Crystal structure of porcine aldehyde reductase ternary complex
30% identity, 97% coverage of query (147 bits)
P87039 D-xylose reductase (EC 1.1.1.307) from Candida tropicalis (see paper)
C1K8Y9 D-xylose reductase (EC 1.1.1.307) from Candida tropicalis (see paper)
34% identity, 96% coverage of query (146 bits)
ALRA_DICDI / Q6IMN8 Aldose reductase A; ARA; Aldehyde reductase A; AlrA; EC 1.1.1.21 from Dictyostelium discoideum (Social amoeba) (see paper)
Q6IMN8 methylglyoxal reductase (NADPH) (EC 1.1.1.283) from Dictyostelium discoideum (see paper)
32% identity, 96% coverage of query (146 bits)
AK1BF_HUMAN / C9JRZ8 Aldo-keto reductase family 1 member B15; Estradiol 17-beta-dehydrogenase AKR1B15; Farnesol dehydrogenase; Testosterone 17beta-dehydrogenase; EC 1.1.1.-; EC 1.1.1.300; EC 1.1.1.54; EC 1.1.1.216; EC 1.1.1.64 from Homo sapiens (Human) (see 3 papers)
C9JRZ8 acetoacetyl-CoA reductase (EC 1.1.1.36); 17beta-estradiol 17-dehydrogenase (EC 1.1.1.62) from Homo sapiens (see paper)
32% identity, 95% coverage of query (145 bits)
Q7Z8L1 glycerol dehydrogenase (NADP+) (EC 1.1.1.72) from Aspergillus nidulans (see paper)
gldB NADP(+)-dependent glycerol dehydrogenase; EC 1.1.1.72 from Emericella nidulans (see paper)
33% identity, 96% coverage of query (145 bits)
I7HD84 D-xylose reductase (EC 1.1.1.307) from Rhizomucor pusillus (see paper)
32% identity, 97% coverage of query (145 bits)
6m7kA Structure of mouse recon (akr1c13) in complex with cyclic amp-amp-gmp (caag)
31% identity, 95% coverage of query (145 bits)
5jgwA / E9JVD4 Crystal structure of maize akr4c13 in complex with NADP and acetate
38% identity, 96% coverage of query (144 bits)
A9QVV8 D-xylose reductase (EC 1.1.1.307) from Candida tropicalis (see paper)
34% identity, 96% coverage of query (144 bits)
1q13A / P80508 Crystal structure of rabbit 20alpha hyroxysteroid dehydrogenase in ternary complex with NADP and testosterone (see paper)
30% identity, 96% coverage of query (144 bits)
5z6tA / P31867 Crystal structure of d-xylose reductase from scheffersomyces stipitis in complex with NADPH (see paper)
33% identity, 96% coverage of query (144 bits)
XYL1 / P31867 NAD(P)H-dependent D-xylose reductase (EC 1.1.1.21; EC 1.1.1.307) from Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545) (see 3 papers)
XYL1_PICST / P31867 NAD(P)H-dependent D-xylose reductase; XR; EC 1.1.1.307 from Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545) (Yeast) (Pichia stipitis) (see paper)
P31867 D-xylose reductase (EC 1.1.1.307) from Scheffersomyces stipitis (see 8 papers)
xyl1 / CAA42072.1 Xylose reductase from Scheffersomyces stipitis (see paper)
33% identity, 96% coverage of query (144 bits)
AK1CA_RAT / D3ZF77 Aldo-keto reductase family 1 member C15; RAKc; EC 1.1.1.-; EC 1.1.1.216 from Rattus norvegicus (Rat) (see 4 papers)
30% identity, 96% coverage of query (144 bits)
A0A455KZK8 D-xylose reductase (EC 1.1.1.307) from Thermomyces lanuginosus (see paper)
34% identity, 96% coverage of query (144 bits)
3ln3A / Q8VC28 Crystal structure of putative reductase (np_038806.2) from mus musculus at 1.18 a resolution
30% identity, 95% coverage of query (144 bits)
5jgyA Crystal structure of maize akr4c13 in p21 space group
38% identity, 96% coverage of query (144 bits)
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