Searching for up to 100 curated homologs for PfGW456L13_2503 FitnessBrowser__pseudo13_GW456_L13:PfGW456L13_2503 (275 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
tesD / Q83VZ6 4,5-9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase (EC 3.7.1.17) from Comamonas testosteroni (see 3 papers)
46% identity, 93% coverage of query (253 bits)
BPHD_PARXL / P47229 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase; HOPDA hydrolase; 2,6-dioxo-6-phenylhexa-3-enoate hydrolase; EC 3.7.1.8 from Paraburkholderia xenovorans (strain LB400) (see 2 papers)
P47229 2,6-dioxo-6-phenylhexa-3-enoate hydrolase (EC 3.7.1.8) from Paraburkholderia xenovorans (see 2 papers)
BphD / CAA46911.1 2-hydroxy-6-oxo-6-phenylhexa-2, 4-dienoate hydrolase from Pseudomonas sp (see paper)
39% identity, 94% coverage of query (174 bits)
2og1A / P47229 Crystal structure of bphd, a c-c hydrolase from burkholderia xenovorans lb400 (see paper)
39% identity, 94% coverage of query (174 bits)
2rhwA Crystal structure of the s112a mutant of a c-c hydrolase, bphd from burkholderia xenovorans lb400, in complex with 3,10-di-fluoro hopda
38% identity, 94% coverage of query (173 bits)
2rhtA Crystal structure of the s112a mutant of a c-c hydrolase, bphd from burkholderia xenovorans lb400, in complex with 3-cl hopda
38% identity, 94% coverage of query (173 bits)
2puhA Crystal structure of the s112a mutant of a c-c hydrolase, bphd from burkholderia xenovorans lb400, in complex with its substrate hopda
38% identity, 94% coverage of query (173 bits)
BPHD_PSEPU / Q52036 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase; HOPDA hydrolase; 2,6-dioxo-6-phenylhexa-3-enoate hydrolase; EC 3.7.1.8 from Pseudomonas putida (Arthrobacter siderocapsulatus) (see paper)
37% identity, 94% coverage of query (171 bits)
BPHD_PSEFK / Q52011 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase; HOPDA hydrolase; 2,6-dioxo-6-phenylhexa-3-enoate hydrolase; EC 3.7.1.8 from Pseudomonas furukawaii (see paper)
bphD / BAA12881.1 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid hydrolase from Pseudomonas oleovorans (see paper)
37% identity, 94% coverage of query (169 bits)
2pujA Crystal structure of the s112a/h265a double mutant of a c-c hydrolase, bphd from burkholderia xenovorans lb400, in complex with its substrate hopda
38% identity, 94% coverage of query (169 bits)
MHPC_COMTE / Q8KZP5 2-hydroxy-6-oxononadienedioate/2-hydroxy-6-oxononatrienedioate hydrolase; 2-hydroxy-6-ketonona-2,4-diene-1,9-dioic acid 5,6-hydrolase; 2-hydroxy-6-oxonona-2,4,7-triene-1,9-dioic acid 5,6-hydrolase; 2-hydroxy-6-oxonona-2,4-diene-1,9-dioic acid 5,6-hydrolase; EC 3.7.1.14 from Comamonas testosteroni (Pseudomonas testosteroni) (see paper)
36% identity, 98% coverage of query (166 bits)
BPHD_PSES1 / P17548 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase; HOPDA hydrolase; 2,6-dioxo-6-phenylhexa-3-enoate hydrolase; EC 3.7.1.8 from Pseudomonas sp. (strain KKS102) (see paper)
36% identity, 98% coverage of query (165 bits)
AGH13449.1 hybrid C-C meta-cleavage hydrolase-carboxylesterase from Cycloclasticus zancles (see paper)
35% identity, 93% coverage of query (162 bits)
B5SU85 2,6-dioxo-6-phenylhexa-3-enoate hydrolase (EC 3.7.1.8) from Dyella ginsengisoli (see paper)
34% identity, 93% coverage of query (152 bits)
hbpD / O06648 2-hydroxy-6-oxo-6-phenyl-2,4-hexadienoate hydrolase [multifunctional] (EC 3.7.1.8) from Pseudomonas nitroreducens (see 2 papers)
33% identity, 94% coverage of query (150 bits)
hsaD / P9WNH5 4,5-9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase monomer (EC 3.7.1.17) from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 3 papers)
HSAD_MYCTU / P9WNH5 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase; 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase; HOPDA hydrolase; Meta-cleavage product hydrolase; MCP hydrolase; EC 3.7.1.17; EC 3.7.1.8 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 4 papers)
P9WNH5 2,6-dioxo-6-phenylhexa-3-enoate hydrolase (EC 3.7.1.8) from Mycobacterium tuberculosis (see paper)
34% identity, 94% coverage of query (149 bits)
5jz9A / P9WNH5 Crystal structure of hsad bound to 3,5-dichloro-4- hydroxybenzenesulphonic acid (see paper)
34% identity, 93% coverage of query (148 bits)
7zm4A Crystal structure of hsad from mycobacterium tuberculosis in complex with cyclipostin-like inhibitor cyc31
34% identity, 93% coverage of query (148 bits)
7zm3A Crystal structure of hsad from mycobacterium tuberculosis in complex with cyclipostin-like inhibitor cyc17
34% identity, 93% coverage of query (148 bits)
7zm2A Crystal structure of hsad from mycobacterium tuberculosis in complex with cyclophostin-like inhibitor cyc8b
34% identity, 93% coverage of query (148 bits)
7zm1A Crystal structure of hsad from mycobacterium tuberculosis in complex with cyclophostin-like inhibitor cyc7b
34% identity, 93% coverage of query (148 bits)
5jzsB Hsad bound to 3,5-dichloro-4-hydroxybenzoic acid
34% identity, 93% coverage of query (148 bits)
5jzbA Crystal structure of hsad bound to 3,5-dichlorobenzene sulphonamide
34% identity, 93% coverage of query (148 bits)
hsaD / Q9KWQ6 4,5-9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase monomer (EC 3.7.1.17) from Rhodococcus jostii (strain RHA1) (see paper)
HSAD_RHOJR / Q9KWQ6 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase; Meta-cleavage product hydrolase; MCP hydrolase; EC 3.7.1.17 from Rhodococcus jostii (strain RHA1) (see 2 papers)
35% identity, 93% coverage of query (147 bits)
2wugA Crystal structure of s114a mutant of hsad from mycobacterium tuberculosis in complex with hopda
34% identity, 93% coverage of query (147 bits)
2wufB Crystal structure of s114a mutant of hsad from mycobacterium tuberculosis in complex with 4,9dsha
34% identity, 93% coverage of query (147 bits)
2wueB Crystal structure of s114a mutant of hsad from mycobacterium tuberculosis in complex with hopoda
34% identity, 93% coverage of query (147 bits)
P96965 2-hydroxymuconate-6-semialdehyde hydrolase (EC 3.7.1.9) from Pseudomonas fluorescens (see 2 papers)
cumD / BAA12150.1 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolase from Pseudomonas fluorescens (see paper)
32% identity, 95% coverage of query (145 bits)
MhpC / b0349 2-hydroxy-6-ketonona-2,4-dienedioate hydrolase (EC 3.7.1.14) from Escherichia coli K-12 substr. MG1655 (see 2 papers)
mhpC / P77044 2-hydroxy-6-ketonona-2,4-dienedioate hydrolase (EC 3.7.1.14) from Escherichia coli (strain K12) (see 10 papers)
MHPC_ECOLI / P77044 2-hydroxy-6-oxononadienedioate/2-hydroxy-6-oxononatrienedioate hydrolase; 2-hydroxy-6-ketonona-2,4-diene-1,9-dioic acid 5,6-hydrolase; 2-hydroxy-6-oxonona-2,4,7-triene-1,9-dioic acid 5,6-hydrolase; 2-hydroxy-6-oxonona-2,4-diene-1,9-dioic acid 5,6-hydrolase; EC 3.7.1.14 from Escherichia coli (strain K12) (see 4 papers)
P77044 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase (EC 3.7.1.14) from Escherichia coli (see 4 papers)
31% identity, 93% coverage of query (144 bits)
1iunB / P96965 Meta-cleavage product hydrolase from pseudomonas fluorescens ip01 (cumd) s103a mutant hexagonal (see paper)
32% identity, 95% coverage of query (144 bits)
1ukaA Crystal structure of a meta-cleavage product hydrolase (cumd) complexed with (s)-2-methylbutyrate
32% identity, 95% coverage of query (144 bits)
1uk9A Crystal structure of a meta-cleavage product hydrolase (cumd) complexed with isovalerate
32% identity, 95% coverage of query (144 bits)
1uk8A Crystal structure of a meta-cleavage product hydrolase (cumd) complexed with n-valerate
32% identity, 95% coverage of query (144 bits)
1uk7A Crystal structure of a meta-cleavage product hydrolase (cumd) complexed with n-butyrate
32% identity, 95% coverage of query (144 bits)
1iupA Meta-cleavage product hydrolase from pseudomonas fluorescens ip01 (cumd) s103a mutant complexed with isobutyrates
32% identity, 95% coverage of query (144 bits)
2d0dA Crystal structure of a meta-cleavage product hydrolase (cumd) a129v mutant
32% identity, 95% coverage of query (144 bits)
bphD / BAA25612.1 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase from Rhodococcus erythropolis (see paper)
34% identity, 93% coverage of query (140 bits)
cbzF / AAX50133.1 CbzF from Pseudomonas putida (see paper)
31% identity, 87% coverage of query (139 bits)
bpdF / AAB17100.1 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase from Rhodococcus sp. M5 (see paper)
30% identity, 92% coverage of query (129 bits)
nahN / BAE92169.1 2-hydroxymuconic semialdehyde hydrolase NahN from Pseudomonas putida (see 2 papers)
32% identity, 95% coverage of query (127 bits)
hppC / AAB81313.1 2-hydroxy-6-ketonona-2,4-dienoate hydrolase from Rhodococcus globerulus (see paper)
32% identity, 98% coverage of query (125 bits)
G3KFX4 2-hydroxymuconate-6-semialdehyde hydrolase (EC 3.7.1.9) from Pseudomonas sp. (see paper)
31% identity, 95% coverage of query (124 bits)
bphD / BAM76235.1 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase from Janibacter sp. TYM3221 (see paper)
33% identity, 95% coverage of query (123 bits)
Build an alignment for PfGW456L13_2503 and 42 homologs with ≥ 30% identity
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cmpF / CAB06612.1 2-hydroxymuconic semialdehyde hydrolase from Sphingomonas sp (see 2 papers)
29% identity, 94% coverage of query (122 bits)
xylF / P23106 2-hydroxymuconic semialdehyde hydrolase (EC 3.7.1.9) from Pseudomonas putida (see paper)
XYLF_PSEPU / P23106 2-hydroxymuconate semialdehyde hydrolase; HMSH; 2-hydroxymuconic semialdehyde hydrolase; EC 3.7.1.9 from Pseudomonas putida (Arthrobacter siderocapsulatus)
32% identity, 95% coverage of query (119 bits)
todF / P23133 2-hydroxy-6-oxohepta-2,4-dienoate hydrolase (EC 3.7.1.25) from Pseudomonas putida (strain ATCC 700007 / DSM 6899 / BCRC 17059 / F1) (see paper)
TODF_PSEP1 / P23133 2-hydroxy-6-oxo-2,4-heptadienoate hydrolase; HOHH; EC 3.7.1.25 from Pseudomonas putida (strain ATCC 700007 / DSM 6899 / BCRC 17059 / F1) (see 2 papers)
28% identity, 95% coverage of query (117 bits)
EstN1 / K0IAM1 pimeloyl-[acyl-carrier protein] methyl ester esterase (EC 3.1.1.85) from Nitrososphaera gargensis (strain Ga9.2) (see paper)
29% identity, 95% coverage of query (114 bits)
4lxhA Crystal structure of the s105a mutant of a carbon-carbon bond hydrolase, dxnb2 from sphingomonas wittichii rw1, in complex with 3- cl hopda (see paper)
29% identity, 93% coverage of query (114 bits)
4lyeA Crystal structure of the s105a mutant of a c-c hydrolase, dxnb2 from sphingomonas wittichii rw1, in complex with substrate hopda
29% identity, 93% coverage of query (114 bits)
4lxiA Crystal structure of the s105a mutant of a carbon-carbon bond hydrolase, dxnb2 from sphingomonas wittichii rw1, in complex with 5, 8-dif hopda
29% identity, 93% coverage of query (114 bits)
bphD / Q75WN8 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase (EC 3.7.1.8) from Rhodococcus jostii (strain RHA1) (see 2 papers)
etbD / BAA18939.1 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase from Rhodococcus sp (see 2 papers)
27% identity, 89% coverage of query (98.6 bits)
AGH13447.1 hybrid C-C meta-cleavage hydrolase-carboxylesterase from Cycloclasticus zancles (see paper)
28% identity, 90% coverage of query (98.2 bits)
Q84II3 2-hydroxy-6-oxo-6-(2-aminophenyl)hexa-2,4-dienoate hydrolase (EC 3.7.1.13) from Janthinobacterium sp. J3 (see paper)
28% identity, 93% coverage of query (95.5 bits)
AGH13448.1 hybrid C-C meta-cleavage hydrolase-carboxylesterase from Cycloclasticus zancles (see paper)
28% identity, 85% coverage of query (94.0 bits)
carC / Q9AQM4 2-hydroxy-6-oxo-6-(2'-aminophenyl)-hexa-2,4dienoate hydrolase monomer (EC 3.7.1.13) from Pseudomonas resinovorans (see paper)
CARC_PSERE / Q9AQM4 2-hydroxy-6-oxo-6-(2'-aminophenyl)hexa-2,4-dienoic acid hydrolase; HOPDA; EC 3.7.1.13 from Pseudomonas resinovorans (see 3 papers)
Q9AQM4 2-hydroxy-6-oxo-6-(2-aminophenyl)hexa-2,4-dienoate hydrolase (EC 3.7.1.13) from Pseudomonas resinovorans (see paper)
carC / BAC41548.1 meta cleavage compound hydrolase from Pseudomonas resinovorans (see 9 papers)
28% identity, 93% coverage of query (93.2 bits)
flnE / BAC75995.1 meta cleavage compound hydrolase from Terrabacter sp. DBF63 (see paper)
26% identity, 86% coverage of query (90.9 bits)
6eb3B Structural and enzymatic characterization of an esterase from a metagenomic library
28% identity, 93% coverage of query (87.4 bits)
6eb3A Structural and enzymatic characterization of an esterase from a metagenomic library
27% identity, 93% coverage of query (87.4 bits)
BPOC_MYCTU / P9WNH1 Putative non-heme bromoperoxidase BpoC from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
26% identity, 95% coverage of query (87.0 bits)
cpoT / GB|AAB86626.1 non-heme chloroperoxidase from Streptomyces aureofaciens (see paper)
28% identity, 93% coverage of query (86.7 bits)
P29715 bromide peroxidase (EC 1.11.1.18) from Kitasatospora aureofaciens (see 2 papers)
bpoA2 / GI|150457 non-heme bromoperoxidase BPO-A2; EC 1.11.1.- from Streptomyces aureofaciens (see 4 papers)
28% identity, 93% coverage of query (85.9 bits)
6eb3C Structural and enzymatic characterization of an esterase from a metagenomic library
28% identity, 93% coverage of query (85.1 bits)
pydB / Q5IH18 4-formamido-2-oxobut-3-enoate deformylase from Rhizobium sp. TAL1145 (see 2 papers)
25% identity, 90% coverage of query (83.6 bits)
5h3hB / K0ACL0 Esterase (eaest) from exiguobacterium antarcticum (see paper)
24% identity, 97% coverage of query (83.2 bits)
Q6DND9 haloalkane dehalogenase (EC 3.8.1.5) from Lyngbya majuscula (see paper)
30% identity, 73% coverage of query (78.2 bits)
cpoL / PDB|1A88_A non-heme chloroperoxidase; EC 1.11.1.10 from Streptomyces lividans (see 2 papers)
cpoL / AAA18642.1 chloroperoxidase from Streptomyces lividans (see paper)
24% identity, 96% coverage of query (75.5 bits)
A0A0H2WW38 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase (EC 4.2.99.20) from Staphylococcus aureus (see paper)
26% identity, 93% coverage of query (73.9 bits)
B2MWN2 soluble epoxide hydrolase (EC 3.3.2.10) from Strongylocentrotus purpuratus (see paper)
24% identity, 93% coverage of query (73.2 bits)
bioH / BAB39459.1 BioH from Kurthia sp. 538-KA26 (see paper)
24% identity, 93% coverage of query (72.0 bits)
4uhfA / A0A0M3KKY6 Structural studies of a thermophilic esterase from thermogutta terrifontis (l37a mutant with butyrate bound) (see paper)
28% identity, 89% coverage of query (71.2 bits)
4uheA Structural studies of a thermophilic esterase from thermogutta terrifontis (malate bound)
28% identity, 89% coverage of query (71.2 bits)
4uhdA Structural studies of a thermophilic esterase from thermogutta terrifontis (acetate bound)
28% identity, 89% coverage of query (71.2 bits)
BPHL_HUMAN / Q86WA6 Valacyclovir hydrolase; VACVase; Valacyclovirase; Biphenyl hydrolase-like protein; Biphenyl hydrolase-related protein; Bph-rp; Breast epithelial mucin-associated antigen; MCNAA; EC 3.1.-.- from Homo sapiens (Human) (see 2 papers)
25% identity, 94% coverage of query (70.5 bits)
2ocgA / Q86WA6 Crystal structure of human valacyclovir hydrolase (see paper)
25% identity, 94% coverage of query (70.5 bits)
2ociA Crystal structure of valacyclovir hydrolase complexed with a product analogue
25% identity, 94% coverage of query (70.5 bits)
8agsAAA / A0A1U9WZ52 8agsAAA
24% identity, 77% coverage of query (70.1 bits)
8agnAAA Alpha/beta epoxide hydrolase
24% identity, 77% coverage of query (70.1 bits)
8agmAAA Alpha/beta epoxide hydrolase
24% identity, 77% coverage of query (70.1 bits)
5ng7B Novel epoxide hydrolases belonging to the alpha/beta hydrolases superfamily in metagenomes from hot environments
24% identity, 77% coverage of query (70.1 bits)
8agpAAA Alpha/beta epoxide hydrolase
24% identity, 77% coverage of query (70.1 bits)
4nvrA / Q8ZRI7 2.22 angstrom resolution crystal structure of a putative acyltransferase from salmonella enterica
26% identity, 77% coverage of query (69.7 bits)
cmtE / Q51980 HOMODA hydrolase from Pseudomonas putida (see 2 papers)
cmtE / AAB62292.1 HOMODA hydrolase from Pseudomonas putida (see 3 papers)
26% identity, 90% coverage of query (67.4 bits)
cpoF / PDB|1A8S non-heme chloroperoxidase; EC 1.11.1.10 from Pseudomonas fluorescens (see 2 papers)
24% identity, 95% coverage of query (66.2 bits)
Q98C03 haloalkane dehalogenase (EC 3.8.1.5) from Mesorhizobium loti (see 2 papers)
27% identity, 93% coverage of query (65.1 bits)
CEEH2_CAEEL / G5EDL5 Epoxide hydrolase 2; EC 3.3.2.10 from Caenorhabditis elegans (see paper)
23% identity, 96% coverage of query (65.1 bits)
6i8wB / Q9KJG6 Crystal structure of a membrane phospholipase a, a novel bacterial virulence factor (see paper)
24% identity, 95% coverage of query (64.3 bits)
Q9KJG6 triacylglycerol lipase (EC 3.1.1.3) from Pseudomonas aeruginosa (see paper)
24% identity, 95% coverage of query (63.9 bits)
4k2aC / E2RV62 Crystal structure of haloalkane dehalogenase dbea from bradyrhizobium elkani usda94 (see paper)
27% identity, 92% coverage of query (58.5 bits)
6o5jA Crystal structure of dad2 bound to quinazolinone derivative
28% identity, 90% coverage of query (58.2 bits)
6ap7A Crystal structure of dad2 in complex with 2-(2-methyl-3-nitroanilino) benzoic acid
28% identity, 90% coverage of query (58.2 bits)
6ap6A / J9U5U9 Crystal structure of dad2 in complex with tolfenamic acid (see paper)
28% identity, 90% coverage of query (58.2 bits)
6brtA / A0A0D9Z3K8 F-box protein cth with hydrolase (see paper)
29% identity, 80% coverage of query (57.8 bits)
D14_ORYSJ / Q10QA5 Strigolactone esterase D14; Protein DWARF 14; Protein DWARF 88; Protein HIGH-TILLERING DWARF 2; EC 3.1.-.- from Oryza sativa subsp. japonica (Rice) (see 11 papers)
29% identity, 80% coverage of query (57.8 bits)
5zhsA Crystal structure of osd14 in complex with covalently bound kk052
29% identity, 80% coverage of query (57.8 bits)
5zhtA Crystal structure of osd14 in complex with covalently bound kk073
29% identity, 80% coverage of query (57.8 bits)
5zhrA Crystal structure of osd14 in complex with covalently bound kk094
29% identity, 80% coverage of query (57.8 bits)
5yz7A Crystal structure of osd14 in complex with d-ring-opened 7'-carba-4bd
29% identity, 80% coverage of query (57.8 bits)
4ihaA Crystal structure of rice dwarf14 (d14) in complex with a gr24 hydrolysis intermediate
29% identity, 80% coverage of query (57.8 bits)
6ap8A Crystal structure of rice d14 bound to 2-(2-methyl-3-nitroanilino) benzoic acid
29% identity, 80% coverage of query (57.8 bits)
5dj5A Crystal structure of rice dwarf14 in complex with synthetic strigolactone gr24
29% identity, 80% coverage of query (57.8 bits)
PIP_HEYCO / P46541 Proline iminopeptidase; PIP; Prolyl aminopeptidase; PAP; EC 3.4.11.5 from Heyndrickxia coagulans (Weizmannia coagulans) (see 3 papers)
pip / GB|BAA01792.1 prolyl aminopeptidase; EC 3.4.11.5 from Bacillus coagulans (see paper)
24% identity, 77% coverage of query (57.4 bits)
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