Searching for up to 100 curated homologs for PfGW456L13_2588 FitnessBrowser__pseudo13_GW456_L13:PfGW456L13_2588 (651 a.a.)

Found high-coverage hits (≥70%) to 27 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

Pf1N1B4_3984 3-methylcrotonyl-CoA carboxylase, alpha (biotin-containing) subunit (EC 6.4.1.4) from Pseudomonas fluorescens FW300-N1B4
    95% identity, 100% coverage of query (1196 bits)

AO356_01595 3-methylcrotonyl-CoA carboxylase, alpha (biotin-containing) subunit (EC 6.4.1.4) from Pseudomonas fluorescens FW300-N2C3
    88% identity, 100% coverage of query (1127 bits)

Pf6N2E2_2194 3-methylcrotonyl-CoA carboxylase, alpha (biotin-containing) subunit (EC 6.4.1.4) from Pseudomonas fluorescens FW300-N2E2
    88% identity, 100% coverage of query (1122 bits)

liuD / Q9I299 methylcrotonyl-CoA carboxylase α-subunit (EC 6.4.1.4) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
Q9I299 methylcrotonoyl-CoA carboxylase (subunit 2/2) (EC 6.4.1.4) from Pseudomonas aeruginosa (see 3 papers)
    75% identity, 99% coverage of query (926 bits)

Sama_1359 3-methylcrotonyl-CoA carboxylase, alpha (biotin-containing) subunit (EC 6.4.1.4) from Shewanella amazonensis SB2B
    51% identity, 99% coverage of query (603 bits)

MCCC1 / Q96RQ3 3-methylcrotonyl-CoA carboxylase α subunit (EC 6.4.1.4) from Homo sapiens (see 4 papers)
MCCA_HUMAN / Q96RQ3 Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial; MCCase subunit alpha; 3-methylcrotonyl-CoA carboxylase 1; 3-methylcrotonyl-CoA carboxylase biotin-containing subunit; 3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha; EC 6.4.1.4 from Homo sapiens (Human) (see 15 papers)
    46% identity, 99% coverage of query (595 bits)

MCCA_MOUSE / Q99MR8 Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial; MCCase subunit alpha; 3-methylcrotonyl-CoA carboxylase 1; 3-methylcrotonyl-CoA carboxylase biotin-containing subunit; 3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha; EC 6.4.1.4 from Mus musculus (Mouse) (see paper)
    46% identity, 99% coverage of query (589 bits)

atuF / Q9HZV6 cis-geranyl-CoA carboxylase α-subunit (EC 6.4.1.5) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
    49% identity, 99% coverage of query (567 bits)

SM_b21124 3-methylcrotonyl-CoA carboxylase, alpha (biotin-containing) subunit (EC 6.4.1.4) from Sinorhizobium meliloti 1021
    49% identity, 99% coverage of query (535 bits)

ACCA1_MYCTU / P9WPQ3 Biotin-dependent 3-methylcrotonyl-coenzyme A carboxylase alpha1 subunit; EC 6.3.4.14 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
CAA79609.1 biotin carboxyl carrier protein from Mycobacterium tuberculosis (see paper)
    47% identity, 96% coverage of query (520 bits)

PCCA_CAEEL / Q19842 Propionyl-CoA carboxylase alpha chain, mitochondrial; PCCase subunit alpha; Propanoyl-CoA:carbon dioxide ligase subunit alpha; EC 6.4.1.3 from Caenorhabditis elegans (see paper)
Q19842 propionyl-CoA carboxylase (subunit 2/2) (EC 6.4.1.3) from Caenorhabditis elegans (see paper)
    42% identity, 99% coverage of query (497 bits)

PCCA_PIG / P0DTA4 Propionyl-CoA carboxylase alpha chain, mitochondrial; PCCase subunit alpha; Propanoyl-CoA:carbon dioxide ligase subunit alpha; EC 6.4.1.3 from Sus scrofa (Pig) (see paper)
    43% identity, 98% coverage of query (491 bits)

7ybuA / P05165 Human propionyl-coenzyme a carboxylase
    43% identity, 98% coverage of query (487 bits)

PCCA / P05165 propionyl-CoA carboxylase α chain, mitochondrial (EC 6.4.1.3) from Homo sapiens (see 4 papers)
PCCA_HUMAN / P05165 Propionyl-CoA carboxylase alpha chain, mitochondrial; PCCase subunit alpha; Propanoyl-CoA:carbon dioxide ligase subunit alpha; EC 6.4.1.3 from Homo sapiens (Human) (see 11 papers)
P05165 propionyl-CoA carboxylase (subunit 1/2) (EC 6.4.1.3) from Homo sapiens (see paper)
    43% identity, 98% coverage of query (486 bits)

PCCA_MOUSE / Q91ZA3 Propionyl-CoA carboxylase alpha chain, mitochondrial; PCCase subunit alpha; Propanoyl-CoA:carbon dioxide ligase subunit alpha; EC 6.4.1.3 from Mus musculus (Mouse) (see paper)
    42% identity, 98% coverage of query (483 bits)

Pcca / P14882 propionyl-CoA carboxylase α subunit (EC 6.4.1.3) from Rattus norvegicus (see paper)
    42% identity, 98% coverage of query (478 bits)

8rthA / Q57YQ4 Trypanosoma brucei 3-methylcrotonyl-coa carboxylase (see paper)
    41% identity, 98% coverage of query (473 bits)

Dsui_0516 Propionyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.3) from Dechlorosoma suillum PS
    42% identity, 99% coverage of query (465 bits)

8sgxX / A0A640KC69 Leishmania tarentolae propionyl-coa carboxylase (alpha-4-beta-6) (see paper)
    40% identity, 98% coverage of query (459 bits)

mccA 3-methylcrotonyl-CoA carboxylase biotin-containig subunit; EC 6.4.1.4 from Emericella nidulans (see paper)
mccA / AAR23110.1 3-methylcrotonyl-CoA carboxylase biotin-containing subunit from Aspergillus nidulans (see paper)
    42% identity, 95% coverage of query (454 bits)

PCCA_HALMT / I3R7G3 Propionyl-CoA carboxylase, biotin carboxylase and biotin-carboxyl carrier subunit; PCC; EC 6.4.1.3; EC 6.3.4.14 from Haloferax mediterranei (strain ATCC 33500 / DSM 1411 / JCM 8866 / NBRC 14739 / NCIMB 2177 / R-4) (Halobacterium mediterranei) (see paper)
I3R7G3 propionyl-CoA carboxylase (subunit 3/3) (EC 6.4.1.3) from Haloferax mediterranei (see paper)
    41% identity, 99% coverage of query (443 bits)

PYCA_METJA / Q58626 Pyruvate carboxylase subunit A; Pyruvic carboxylase A; EC 6.4.1.1 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see paper)
    47% identity, 73% coverage of query (438 bits)

8hz4A / A9W9X0 The tetrameric structure of biotin carboxylase from chloroflexus aurantiacus in complex with bicarbonate
    52% identity, 70% coverage of query (421 bits)

accC / A9W9X0 biotin carboxylase (EC 6.3.4.14) from Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl) (see paper)
A9W9X0 biotin carboxylase (EC 6.3.4.14) from Chloroflexus aurantiacus (see paper)
    45% identity, 93% coverage of query (417 bits)

A0A1U7EYC1 biotin carboxylase (EC 6.3.4.14) from Natronomonas pharaonis (see paper)
    48% identity, 71% coverage of query (398 bits)

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Build an alignment for PfGW456L13_2588 and 25 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

ACAC_YEAST / Q00955 Acetyl-CoA carboxylase; ACC; Fatty acid synthetase 3; mRNA transport-defective protein 7; EC 6.4.1.2; EC 6.3.4.14 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 13 papers)
Q00955 biotin carboxylase (EC 6.3.4.14); acetyl-CoA carboxylase (EC 6.4.1.2) from Saccharomyces cerevisiae (see 6 papers)
    27% identity, 98% coverage of query (232 bits)

5cslA / Q00955 Crystal structure of the 500 kd yeast acetyl-coa carboxylase holoenzyme dimer (see paper)
    27% identity, 98% coverage of query (212 bits)

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