Searching for up to 100 curated homologs for PfGW456L13_2816 FitnessBrowser__pseudo13_GW456_L13:PfGW456L13_2816 (282 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
Ac3H11_2560 ABC transporter for L-Histidine, ATPase component from Acidovorax sp. GW101-3H11
54% identity, 82% coverage of query (251 bits)
TC 3.A.1.17.4 / Q2BM69 Putative taurin uptake ABC transporter ATP-binding protein, component of The taurine uptake system, TauABC from Neptuniibacter caesariensis
46% identity, 84% coverage of query (226 bits)
NRTD_SYNE7 / P38046 Nitrate import ATP-binding protein NrtD; EC 7.3.2.4 from Synechococcus elongatus (strain ATCC 33912 / PCC 7942 / FACHB-805) (Anacystis nidulans R2) (see paper)
TC 3.A.1.16.1 / P38046 NrtD, component of Four component nitrate/nitrite porter (see paper)
45% identity, 81% coverage of query (214 bits)
TauB / b0366 taurine ABC transporter ATP binding subunit (EC 7.6.2.7) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
TauB / Q47538 taurine ABC transporter ATP binding subunit (EC 7.6.2.7) from Escherichia coli (strain K12) (see 3 papers)
TAUB_ECOLI / Q47538 Taurine import ATP-binding protein TauB; EC 7.6.2.7 from Escherichia coli (strain K12) (see 2 papers)
TC 3.A.1.17.1 / Q47538 TauB aka SSIB aka B0366, component of Taurine (2-aminoethane sulfonate) porter from Escherichia coli (see 4 papers)
46% identity, 79% coverage of query (212 bits)
Q6RH47 taurine dehydrogenase (EC 1.4.99.2) from Paracoccus pantotrophus (see paper)
46% identity, 83% coverage of query (211 bits)
NRTC_SYNE7 / P38045 Nitrate import ATP-binding protein NrtC; EC 7.3.2.4 from Synechococcus elongatus (strain ATCC 33912 / PCC 7942 / FACHB-805) (Anacystis nidulans R2) (see 2 papers)
TC 3.A.1.16.1 / P38045 NrtC, component of Four component nitrate/nitrite porter (see paper)
45% identity, 84% coverage of query (208 bits)
CMPC_SYNE7 / Q55107 Bicarbonate transport ATP-binding protein CmpC; EC 7.6.2.- from Synechococcus elongatus (strain ATCC 33912 / PCC 7942 / FACHB-805) (Anacystis nidulans R2) (see paper)
TC 3.A.1.16.3 / Q55107 CmpC, component of Bicarbonate porter (activated by low [CO2] mediated by CmpR; (Nishimura et al., 2008)) (see 2 papers)
44% identity, 87% coverage of query (207 bits)
SSUB_BACSU / P97027 Aliphatic sulfonates import ATP-binding protein SsuB; EC 7.6.2.14 from Bacillus subtilis (strain 168) (see paper)
42% identity, 82% coverage of query (204 bits)
CMPD_SYNE7 / Q55108 Bicarbonate transport ATP-binding protein CmpD; EC 7.6.2.- from Synechococcus elongatus (strain ATCC 33912 / PCC 7942 / FACHB-805) (Anacystis nidulans R2) (see paper)
TC 3.A.1.16.3 / Q55108 CmpD, component of Bicarbonate porter (activated by low [CO2] mediated by CmpR; (Nishimura et al., 2008)) (see 2 papers)
44% identity, 82% coverage of query (202 bits)
TC 3.A.1.16.2 / O05347 CynD, component of Bispecific cyanate/nitrite transporter
46% identity, 82% coverage of query (198 bits)
TC 3.A.1.17.5 / C0LZR9 OphH, component of The phthalate uptake system, OphFGH from Burkholderia cepacia
42% identity, 86% coverage of query (194 bits)
TC 3.A.1.16.4 / Q8YRV8 Nitrate transport ATP-binding protein of ABC transporter, component of Nitrate uptake system, NrtABCD from Nostoc sp. (strain PCC 7120 / UTEX 2576) (see paper)
40% identity, 88% coverage of query (185 bits)
AZOBR_RS18550 ABC transporter for nitrate, ATPase component from Azospirillum brasilense Sp245
42% identity, 80% coverage of query (184 bits)
TC 3.A.1.17.2 / Q8KZQ6 Aliphatic sulfonates import ATP-binding protein SsuB, component of Aromatic sulfonate porter (see 3 papers)
45% identity, 74% coverage of query (167 bits)
SsuB / b0933 aliphatic sulfonate ABC transporter ATP binding subunit (EC 7.6.2.14) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
SsuB / P0AAI1 aliphatic sulfonate ABC transporter ATP binding subunit (EC 7.6.2.14) from Escherichia coli (strain K12) (see 3 papers)
SSUB_ECOLI / P0AAI1 Aliphatic sulfonates import ATP-binding protein SsuB; EC 7.6.2.14 from Escherichia coli (strain K12) (see paper)
TC 3.A.1.17.10 / B1X8N7 Aliphatic sulfonates import ATP-binding protein SsuB, component of Aliphatic sulfonate (alkanesulfonate) import permease, SsuABC (YcbOEM) and is regluated by the transcriptional activator, Cbl from Escherichia coli (strain K12 / DH10B)
49% identity, 72% coverage of query (167 bits)
TC 3.A.1.20.1 / O54370 BitD, component of The iron transporter, BitABCDEF from Treponema hyodysenteriae (Serpulina hyodysenteriae) (see paper)
42% identity, 72% coverage of query (166 bits)
SSUB_CORGL / Q8NR42 Aliphatic sulfonates import ATP-binding protein SsuB; EC 7.6.2.14 from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see paper)
TC 3.A.1.17.12 / Q8NR42 Aliphatic sulfonates import ATP-binding protein SsuB, component of Sulfonate and sulfonate ester uptake transporter, SsuABC from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025)
39% identity, 91% coverage of query (165 bits)
TC 3.A.1.20.3 / A3N296 Ferric ABC transporter ATP-binding protein, component of Iron (Fe3+) uptake porter, AfuABC (FbpABC) (Chin et al. 1996). AfuA has been characterized from Actinobacillus pleuropneumoniae serotype 5b (strain L20)
41% identity, 79% coverage of query (164 bits)
Ac3H11_2066 glucose ABC transporter, ATPase component from Acidovorax sp. GW101-3H11
38% identity, 83% coverage of query (164 bits)
PotA / b1126 spermidine preferential ABC transporter ATP binding subunit (EC 7.6.2.11; EC 7.6.2.16) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
PotA / P69874 spermidine preferential ABC transporter ATP binding subunit (EC 7.6.2.11) from Escherichia coli (strain K12) (see 5 papers)
POTA_ECOLI / P69874 Spermidine/putrescine import ATP-binding protein PotA; EC 7.6.2.11 from Escherichia coli (strain K12) (see 6 papers)
TC 3.A.1.11.1 / P69874 Spermidine/putrescine import ATP-binding protein PotA aka B1126, component of Polyamine (putrescine/spermidine) uptake porter from Escherichia coli (see 9 papers)
potA / MB|P69874 spermidine/putrescine ABC transporter, ATP-binding protein PotA; EC 3.6.3.31 from Escherichia coli K12 (see 10 papers)
47% identity, 70% coverage of query (162 bits)
2d62A / O57933 Crystal structure of multiple sugar binding transport atp- binding protein
38% identity, 74% coverage of query (150 bits)
MALK_SALTY / P19566 Maltose/maltodextrin import ATP-binding protein MalK; EC 7.5.2.1 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
34% identity, 87% coverage of query (133 bits)
7w78A / Q6NEF2 Heme exporter hrtba in complex with mg-amppnp (see paper)
41% identity, 73% coverage of query (128 bits)
7w79A Heme exporter hrtba in complex with mn-amppnp
41% identity, 73% coverage of query (128 bits)
1f3oA / Q58206 Crystal structure of mj0796 atp-binding cassette (see paper)
37% identity, 73% coverage of query (126 bits)
1oxvD Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus
36% identity, 73% coverage of query (125 bits)
1oxvA Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus
36% identity, 73% coverage of query (125 bits)
GLCV_SACS2 / Q97UY8 Glucose import ATP-binding protein GlcV; EC 7.5.2.- from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see 3 papers)
TC 3.A.1.1.13 / Q97UY8 GlcV, component of Glucose, mannose, galactose porter from Sulfolobus solfataricus (see 3 papers)
1oxuA / Q97UY8 Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus (see paper)
36% identity, 73% coverage of query (125 bits)
5xu1B / Q8DQF8 Structure of a non-canonical abc transporter from streptococcus pneumoniae r6 (see paper)
36% identity, 76% coverage of query (125 bits)
FTSE_MYCTA / A5U7B7 Cell division ATP-binding protein FtsE from Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra) (see 2 papers)
40% identity, 71% coverage of query (124 bits)
8iddA Cryo-em structure of mycobacterium tuberculosis atp bound ftsex/ripc complex in peptidisc
40% identity, 71% coverage of query (124 bits)
8igqA / O05779 Cryo-em structure of mycobacterium tuberculosis adp bound ftsex/ripc complex in peptidisc (see paper)
40% identity, 71% coverage of query (124 bits)
MetN / b0199 L-methionine/D-methionine ABC transporter ATP binding subunit (EC 7.4.2.11) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
MetN / P30750 L-methionine/D-methionine ABC transporter ATP binding subunit (EC 7.4.2.11) from Escherichia coli (strain K12) (see 3 papers)
METN_ECOLI / P30750 Methionine import ATP-binding protein MetN; EC 7.4.2.11 from Escherichia coli (strain K12) (see 7 papers)
P30750 ABC-type methionine transporter (subunit 2/2) (EC 7.4.2.11) from Escherichia coli (see 3 papers)
TC 3.A.1.24.1 / P30750 MetN, D-methionine transport ATP-binding protein, component of The L- and D-methionine porter (also transports formyl-L-methionine and other methionine derivatives) (Zhang et al., 2003). The 3.7A structure of MetNI has been solved. An allosteric regulatory mechanism operates at the level of transport activity, so increased intracellular levels of the transported ligand stabilize an inward-facing, ATPase-inactive state of MetNI to inhibit further ligand translocation into the cell from Escherichia coli (see 5 papers)
34% identity, 80% coverage of query (122 bits)
6z4wA / Q8DQH4 Ftse structure from streptococcus pneumoniae in complex with adp (space group p 1) (see paper)
33% identity, 72% coverage of query (121 bits)
6z67B Ftse structure of streptococcus pneumoniae in complex with amppnp at 2.4 a resolution
33% identity, 72% coverage of query (121 bits)
3tuzC Inward facing conformations of the metni methionine abc transporter: cy5 semet soak crystal form
33% identity, 80% coverage of query (121 bits)
3tuiC Inward facing conformations of the metni methionine abc transporter: cy5 native crystal form
33% identity, 80% coverage of query (121 bits)
6cvlD / P30750 Crystal structure of the escherichia coli atpgs-bound metni methionine abc transporter in complex with its metq binding protein (see paper)
33% identity, 80% coverage of query (121 bits)
4u00A / Q5SJ55 Crystal structure of ttha1159 in complex with adp (see paper)
36% identity, 83% coverage of query (118 bits)
3c4jA Abc protein artp in complex with atp-gamma-s
35% identity, 79% coverage of query (113 bits)
3c41J / D0VWX4 Abc protein artp in complex with amp-pnp/mg2+
35% identity, 79% coverage of query (113 bits)
2olkA Abc protein artp in complex with adp-beta-s
35% identity, 79% coverage of query (113 bits)
2oljA Abc protein artp in complex with adp/mg2+
35% identity, 79% coverage of query (113 bits)
4ymuJ / Q8RCC2 Crystal structure of an amino acid abc transporter complex with arginines and atps (see paper)
34% identity, 71% coverage of query (113 bits)
ECFA1_STRT2 / Q5M243 Energy-coupling factor transporter ATP-binding protein EcfA1; ECF transporter A component EcfA1; EC 7.-.-.- from Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311) (see paper)
TC 3.A.1.25.6 / Q5M243 Energy-coupling factor transporter ATP-binding protein EcfA 2, component of Riboflavin ECF transport system, EcfAA'T/RibU from Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311)
32% identity, 78% coverage of query (109 bits)
LolD / b1117 lipoprotein release complex - ATP binding subunit from Escherichia coli K-12 substr. MG1655 (see 2 papers)
LolD / P75957 lipoprotein release complex - ATP binding subunit from Escherichia coli (strain K12) (see paper)
LOLD_ECOLI / P75957 Lipoprotein-releasing system ATP-binding protein LolD; EC 7.6.2.- from Escherichia coli (strain K12) (see paper)
TC 3.A.1.125.1 / P75957 LolD aka B1117, component of Lipoprotein translocation system (translocates lipoproteins from the inner membrane to periplasmic chaperone, LolA, which transfers the lipoproteins to an outer membrane receptor, LolB, which anchors the lipoprotein to the outer membrane of the Gram-negative bacterial cell envelope) (see 1.B.46; Narita et al., 2003; Ito et al., 2006; Watanabe et al., 2007). The structure of ligand-bound LolCDE has been solved (Ito et al., 2006). LolC and LolE each have 4 TMSs (1+3). Unlike most ATP binding cassette transporters mediating the transmembrane flux of substrates, the LolCDE complex catalyzes the extrusion of lipoproteins anchored to the outer leaflet of the inner membrane. The LolCDE complex is unusual in that it can be purified as a liganded form, which is an intermediate of the lipoprotein release reaction (Taniguchi and Tokuda, 2008). LolCDE has been reconstituted from separated subunits from Escherichia coli (see 5 papers)
lolD / GB|BAA35937.2 lipoprotein releasing system, ATP-binding protein; EC 3.6.3.- from Escherichia coli K12 (see 5 papers)
36% identity, 73% coverage of query (108 bits)
7d0aB Acinetobacter mlafedb complex in adp-vanadate trapped vclose conformation
34% identity, 73% coverage of query (108 bits)
7d08B / A0A086HZU3 Acinetobacter mlafedb complex in atp-bound vtrans1 conformation (see paper)
34% identity, 73% coverage of query (108 bits)
7mdyC Lolcde nucleotide-bound
36% identity, 73% coverage of query (107 bits)
6z5uK Cryo-em structure of the a. Baumannii mlabdef complex bound to appnhp
34% identity, 73% coverage of query (107 bits)
7v8iD / P75957 Lolcd(e171q)e with bound amppnp in nanodiscs (see paper)
36% identity, 73% coverage of query (107 bits)
5lilA / Q2EHL8 Structure of aggregatibacter actinomycetemcomitans macb bound to atpys (p21) (see paper)
35% identity, 76% coverage of query (106 bits)
2pclA / O66646 Crystal structure of abc transporter with complex (aq_297) from aquifex aeolicus vf5
35% identity, 71% coverage of query (106 bits)
5lj7A / Q2EHL8 Structure of aggregatibacter actinomycetemcomitans macb bound to atp (p21) (see paper)
35% identity, 76% coverage of query (106 bits)
7arlD Lolcde in complex with lipoprotein and adp
36% identity, 71% coverage of query (106 bits)
5ws4A / A0A0D8G707 Crystal structure of tripartite-type abc transporter macb from acinetobacter baumannii (see paper)
33% identity, 78% coverage of query (105 bits)
P9WQK5 Uncharacterized ABC transporter ATP-binding protein Rv0073 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
35% identity, 74% coverage of query (103 bits)
MacB / b0879 ABC-type tripartite efflux pump ATP binding/membrane subunit from Escherichia coli K-12 substr. MG1655 (see 14 papers)
MacB / P75831 ABC-type tripartite efflux pump ATP binding/membrane subunit from Escherichia coli (strain K12) (see 16 papers)
MACB_ECOLI / P75831 Macrolide export ATP-binding/permease protein MacB; EC 7.6.2.- from Escherichia coli (strain K12) (see 5 papers)
TC 3.A.1.122.1 / P75831 MacB aka B0879, component of Macrolide (14- and 15- but not 16-membered lactone macrolides including erythromycin) exporter, MacAB (formerly YbjYZ). Both MacA and MacB are required for activity (Tikhonova et al., 2007). MacAB functions with TolC to export multiple drugs and heat-stable enterotoxin II (enterotoxin STII) (Yamanaka et al., 2008). The crystal structure of MacA is available (Yum et al., 2009). MacB is a dimer whose ATPase activity and macrolide-binding capacity are regulated by the membrane fusion protein MacA (Lin et al., 2009). Xu et al. (2009) have reported the crystal structure of the periplasmic region of MacB which they claim resembles the periplasmic domain of RND-type transporters such as AcrB (TC# 2.A.6.2.2). Also exports L-cysteine (Yamada et al., 2006). The periplasmic membrane proximal domain of MacA acts as a switch in stimulation of ATP hydrolysis by the MacB transporter from Escherichia coli (see 5 papers)
macB / BAB64542.1 macrolide-specific ABC-type efflux carrier from Escherichia coli (see paper)
33% identity, 76% coverage of query (100 bits)
P0AAH0 Phosphate import ATP-binding protein PstB; ABC phosphate transporter; Phosphate-transporting ATPase; EC 7.3.2.1 from Escherichia coli (strain K12)
32% identity, 83% coverage of query (99.8 bits)
7chaI / Q9HVW1 Cryo-em structure of p.Aeruginosa mlafebd with amppnp (see paper)
33% identity, 76% coverage of query (99.0 bits)
7z18I E. Coli c-p lyase bound to a phnk abc dimer and atp
35% identity, 72% coverage of query (97.4 bits)
7z15I / P16678 E. Coli c-p lyase bound to a phnk/phnl dual abc dimer and adp + pi (see paper)
35% identity, 72% coverage of query (97.4 bits)
TGD3_ARATH / Q9AT00 Protein TRIGALACTOSYLDIACYLGLYCEROL 3, chloroplastic; ABC transporter I family member 13; ABC transporter ABCI.13; AtABCI13; Non-intrinsic ABC protein 11; AtNAP11 from Arabidopsis thaliana (Mouse-ear cress) (see 6 papers)
TC 3.A.1.27.2 / Q9AT00 Tdg3, component of The chloroplast lipid (trigalactosyl diacyl glycerol (TDG)) transporter, Tdg1,2,3 (Lu et al., 2007). Lipids such as mono- and digalactolipids are synthesized in the endoplasmic reticulum (ER) of plant cells and transferred to the thylakoid membranes of chloroplasts. Mutations in an outer chloroplastic envelope protein with 350 aas and 7 putative TMSs in the last 250 residues may catalyze translocation as part of a lipid transfer complex from Arabidopsis thaliana (Mouse-ear cress) (see 7 papers)
32% identity, 76% coverage of query (97.4 bits)
7z16I E. Coli c-p lyase bound to phnk/phnl dual abc dimer with amppnp and phnk e171q mutation
34% identity, 72% coverage of query (96.3 bits)
ABCA3_HUMAN / Q99758 Phospholipid-transporting ATPase ABCA3; ABC-C transporter; ATP-binding cassette sub-family A member 3; ATP-binding cassette transporter 3; ATP-binding cassette 3; Xenobiotic-transporting ATPase ABCA3; EC 7.6.2.1; EC 7.6.2.2 from Homo sapiens (Human) (see 18 papers)
TC 3.A.1.211.5 / Q99758 The surfactant-secreting porter, ABCA3 (exports lipids and proteins into lamellar bodies). Fatal surfactant deficiency (FSD) can result from mutations in ABCA3, causing abnormal intracellular localization (type I) or decreased ATP hydrolysis (type II). Other mutations cause pediatric interstitial lung disease (pILD) from Homo sapiens (Human) (see 7 papers)
ABCA3 / RF|NP_001080.2 ATP-binding cassette sub-family A member 3 from Homo sapiens (see paper)
30% identity, 73% coverage of query (95.1 bits)
5x40A / O68106 Structure of a cbio dimer bound with amppcp (see paper)
35% identity, 71% coverage of query (94.7 bits)
7w02A / Q99758 Cryo-em structure of atp-bound abca3 (see paper)
30% identity, 73% coverage of query (93.6 bits)
4hluA / Q9WY65 Structure of the ecfa-a' heterodimer bound to adp (see paper)
31% identity, 79% coverage of query (92.4 bits)
7ch6C / P63386 Cryo-em structure of e.Coli mlafeb with amppnp (see paper)
32% identity, 74% coverage of query (92.0 bits)
6xgyA Crystal structure of e. Coli mlafb abc transport subunits in the dimeric state
32% identity, 74% coverage of query (92.0 bits)
7cgnB The overall structure of the mlafedb complex in atp-bound eqtall conformation (mutation of e170q on mlaf)
31% identity, 74% coverage of query (90.5 bits)
4zirA Crystal structure of ecfaa' heterodimer bound to amppnp
30% identity, 79% coverage of query (90.5 bits)
4hluC / Q9X1Z1 Structure of the ecfa-a' heterodimer bound to adp (see paper)
32% identity, 76% coverage of query (89.4 bits)
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8bmpB / Q1GBI9 Cryo-em structure of the folate-specific ecf transporter complex in msp2n2 lipid nanodiscs bound to atp and adp (see paper)
29% identity, 77% coverage of query (89.0 bits)
5d3mB Folate ecf transporter: amppnp bound state
29% identity, 77% coverage of query (89.0 bits)
ABCB6_MOUSE / Q9DC29 ATP-binding cassette sub-family B member 6; ABC-type heme transporter ABCB6; EC 7.6.2.5 from Mus musculus (Mouse) (see 7 papers)
33% identity, 77% coverage of query (89.0 bits)
ECFA2_STRT2 / Q5M244 Energy-coupling factor transporter ATP-binding protein EcfA2; ECF transporter A component EcfA2; EC 3.6.3.- from Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311) (see paper)
TC 3.A.1.25.6 / Q5M244 Energy-coupling factor transporter ATP-binding protein EcfA 1, component of Riboflavin ECF transport system, EcfAA'T/RibU from Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311)
32% identity, 76% coverage of query (89.0 bits)
ABCA6_HUMAN / Q8N139 ATP-binding cassette sub-family A member 6; EC 7.6.2.- from Homo sapiens (Human) (see 3 papers)
TC 3.A.1.211.15 / Q8N139 ATP-binding cassette sub-family A member 6, ABCA6 of 1617 aas. This transporter may play a role in macrophage lipid homeostasis. It is up-regulated during monocyte differentiation into macrophages but down-regulated by cholesterol loading of macrophages from Homo sapiens
30% identity, 78% coverage of query (87.8 bits)
2onjA Structure of the multidrug abc transporter sav1866 from s. Aureus in complex with amp-pnp
32% identity, 77% coverage of query (87.8 bits)
Y1866_STAAM / Q99T13 Putative multidrug export ATP-binding/permease protein SAV1866; EC 7.6.2.- from Staphylococcus aureus (strain Mu50 / ATCC 700699) (see paper)
Q99T13 ABC-type xenobiotic transporter (EC 7.6.2.2) from Staphylococcus aureus (see paper)
TC 3.A.1.106.2 / Q2G2M9 The homodimeric Sav1866 multidrug exporter (transports doxorubicin, verapamil, ethidium, tetraphenylphosphonium, vinblastine and the fluorescent dye, Hoechst 33342; 3-D structure known at 3 Å resolution; Dawson and Locher, 2006; Velamakanni et al., 2008) The empty site opens by rotation of the nucleotide-binding domain whereas the ATP-bound site remains occluded (Jones and George, 2011). Conformational changes induced by ATP-binding and hydrolysis have been proposed (Becker et al. 2010; Oliveira et al., 2011). The alternating access mechanism and the flippase activity of this ABC exporter has been shown to be lipid-dependent (Becker et al. 2010; Oliveira et al., 2011). The alternating access mechanism and the flippase activity of this ABC exporter has been shown to be lipid-dependent from Staphylococcus aureus (strain NCTC 8325)
2hydA / Q99T13 Multidrug abc transporter sav1866 (see paper)
32% identity, 77% coverage of query (87.8 bits)
8bmsB Cryo-em structure of the mutant solitary ecf module 2eq in msp2n2 lipid nanodiscs in the atpase closed and atp-bound conformation
28% identity, 77% coverage of query (87.8 bits)
ABCA3_MOUSE / Q8R420 Phospholipid-transporting ATPase ABCA3; ATP-binding cassette sub-family A member 3; Xenobiotic-transporting ATPase ABCA3; EC 7.6.2.1; EC 7.6.2.2 from Mus musculus (Mouse) (see 7 papers)
28% identity, 73% coverage of query (85.1 bits)
3nh9A Nucleotide binding domain of human abcb6 (atp bound structure)
32% identity, 83% coverage of query (85.1 bits)
8k7bA Post-occluded structure of human abcb6 w546a mutant (adp/vo4-bound)
32% identity, 77% coverage of query (85.1 bits)
7dnzB Cryo-em structure of the human abcb6 (hemin and gsh-bound)
32% identity, 77% coverage of query (84.7 bits)
7dnzA / Q9NP58 Cryo-em structure of the human abcb6 (hemin and gsh-bound) (see paper)
32% identity, 77% coverage of query (84.7 bits)
7dnyB Cryo-em structure of the human abcb6 (coproporphyrin iii-bound)
32% identity, 77% coverage of query (84.7 bits)
7ch8I Cryo-em structure of p.Aeruginosa mlafebd with adp-v
34% identity, 76% coverage of query (84.7 bits)
6mjpA / O30650 Lptb(e163q)fgc from vibrio cholerae (see paper)
28% identity, 70% coverage of query (84.3 bits)
ABCB6_HUMAN / Q9NP58 ATP-binding cassette sub-family B member 6; ABC-type heme transporter ABCB6; Mitochondrial ABC transporter 3; Mt-ABC transporter 3; P-glycoprotein-related protein; Ubiquitously-expressed mammalian ABC half transporter; EC 7.6.2.5 from Homo sapiens (Human) (see 23 papers)
TC 3.A.1.210.6 / Q9NP58 Mitochondrial outer membrane/lysosome anionic porphyrin uptake half ABC transporter, ABCB6. Expressed in many mammalian tissues (including fetal liver) in response to intracellular porphyrin. Porphyrin uptake activates de novo porphyrin (haem) biosynthesis from Homo sapiens (Human) (see 7 papers)
ABCB6 / RF|NP_005680.1 ATP-binding cassette sub-family B member 6, mitochondrial from Homo sapiens (see paper)
32% identity, 77% coverage of query (84.3 bits)
1jj7A / Q03518 Crystal structure of thE C-terminal atpase domain of human tap1 (see paper)
29% identity, 72% coverage of query (84.0 bits)
2pmkA Crystal structures of an isolated abc-atpase in complex with tnp-adp
29% identity, 77% coverage of query (84.0 bits)
2ff7A The abc-atpase of the abc-transporter hlyb in the adp bound state
29% identity, 77% coverage of query (84.0 bits)
5l22B / O67184 Prtd t1ss abc transporter (see paper)
30% identity, 74% coverage of query (83.6 bits)
7eklA Mitochondrial outer membrane protein
32% identity, 77% coverage of query (83.2 bits)
4zirB Crystal structure of ecfaa' heterodimer bound to amppnp
32% identity, 76% coverage of query (82.8 bits)
7sgrE / Q8FDZ8 Structure of hemolysin a secretion system hlyb/d complex (see paper)
29% identity, 77% coverage of query (82.8 bits)
3b5jA Crystal structures of the s504a mutant of an isolated abc-atpase in complex with tnp-adp
29% identity, 77% coverage of query (82.8 bits)
3nhaA Nucleotide binding domain of human abcb6 (adp mg bound structure)
32% identity, 83% coverage of query (82.4 bits)
7wixB / P9WQJ7 Cryo-em structure of mycobacterium tuberculosis irtab in complex with adp
34% identity, 74% coverage of query (82.4 bits)
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Lawrence Berkeley National Laboratory