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Searching for up to 100 curated homologs for PfGW456L13_2878 FitnessBrowser__pseudo13_GW456_L13:PfGW456L13_2878 (353 a.a.)

Found high-coverage hits (≥70%) to 32 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

TC 3.A.1.5.24 / Q7CQ74 YejB, component of The antimicrobial peptide (protamine, melittin, polymyxin B, human defensin (HBD)-1 and HBD-2 exporter, YejABEF (Eswarappa et al., 2008). Prefers N-formyl methionine peptides, such as Microcin C (of prokaryotic origin) to non formylated peptides (of eukaryotic origin) from Salmonella typhimurium (see paper)
    62% identity, 99% coverage of query (451 bits)

YejB / b2178 putative oligopeptide ABC transporter membrane subunit YejB (EC 7.4.2.6) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
YejB / P0AFU0 putative oligopeptide ABC transporter membrane subunit YejB (EC 7.4.2.6) from Escherichia coli (strain K12) (see 3 papers)
TC 3.A.1.5.21 / P0AFU1 YejB, component of The Microcin C/peptide uptake porter, YejABEF from Escherichia coli O157:H7 (see 2 papers)
yejB / RF|NP_416683 inner membrane ABC transporter permease protein yejB from Escherichia coli K12 (see 5 papers)
    62% identity, 99% coverage of query (449 bits)

TC 3.A.1.5.20 / P42062 AppB, component of 5-6 amino acyl oligopeptide transporter AppA-F from Bacillus subtilis (see 3 papers)
    34% identity, 99% coverage of query (181 bits)

appB / GB|CAB12996.1 oligopeptide ABC transporter, permease protein AppB from Bacillus subtilis (see 2 papers)
    32% identity, 99% coverage of query (166 bits)

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Build an alignment for PfGW456L13_2878 and 4 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

Q5V9S1 ABC-type oligopeptide transporter (EC 7.4.2.6) from Vibrio fluvialis (see paper)
TC 3.A.1.5.22 / Q5V9S1 OppB, component of The peptide transporter OppA,B,C,D,F (influences biofilm formation; Lee et al., 2004). Similar to 3.A.1.5.1, OppA is similar to the Vibrio furnissii OppA that provides several functions: hemolysis, antibiotic resistance, and virulence from Vibrio fluvialis (see paper)
    29% identity, 99% coverage of query (154 bits)

DppB / b3543 dipeptide ABC transporter membrane subunit DppB (EC 7.4.2.9) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
dppB / P0AEF8 dipeptide ABC transporter membrane subunit DppB (EC 7.4.2.9) from Escherichia coli (strain K12) (see paper)
DPPB_ECOLI / P0AEF8 Dipeptide transport system permease protein DppB from Escherichia coli (strain K12) (see 4 papers)
dppB / GB|AAC76568.1 dipeptide ABC transporter, permease protein DppB from Escherichia coli (see 7 papers)
    33% identity, 98% coverage of query (154 bits)

TC 3.A.1.5.15 / Q9X269 TM1747, component of Probable mannose/mannoside porter. Induced by beta-mannan (Conners et al., 2005). Regulated by mannose-responsive regulator manR (see paper)
    31% identity, 94% coverage of query (152 bits)

TC 3.A.1.5.1 / P08005 OppB aka STM1745, component of Oligopeptide porter (also takes up amino glycoside antibiotics such as kanamycin, streptomycin and neomycin as well as cell wall-derived peptides such as murein tripeptide). It transports substrate peptides of 2-5 amino acids with highest affinity for tripeptides. Also transports δ-aminolevulinic acid (ALA). [May be regulated by PTS Enzyme INtr-aspartokinase.] ATP-binding to OppDF may result in donation of peptide to OppBC and simultaneous release of OppA from Salmonella typhimurium (see 3 papers)
    28% identity, 99% coverage of query (149 bits)

DPPB_PSEAB / A0A0H2ZGW7 Di/tripeptide transport system permease protein DppB from Pseudomonas aeruginosa (strain UCBPP-PA14) (see paper)
TC 3.A.1.5.39 / W0WN20 Dipeptide transport system permease protein dppB, component of Di- and tri-peptide transporter, DppBCDF with periplasmic substrate binding receptors, A1, A3, A5, A7 and A9, each with differing specificities for peptides from Pseudomonas aeruginosa MH38
    32% identity, 98% coverage of query (148 bits)

TC 3.A.1.5.32 / F0TFS8 Oligopeptide transport protein, component of ABC α-galactoside uptake porter from Lactobacillus acidophilus (strain 30SC)
    28% identity, 98% coverage of query (144 bits)

OppB / b1244 murein tripeptide ABC transporter / oligopeptide ABC transporter inner membrane subunit OppB (EC 7.4.2.6) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
oppB / P0AFH2 murein tripeptide ABC transporter / oligopeptide ABC transporter inner membrane subunit OppB (EC 7.4.2.6) from Escherichia coli (strain K12) (see 3 papers)
TC 3.A.1.5.41 / P0AFH2 Oligopeptide transport system permease protein OppB, component of Oligopeptide transporter, OppABCDF/MppA/YgiS from Escherichia coli (strain K12)
oppB / ECOCYC|OPPB-MONOMER oligopeptide transport system permease protein oppB from Escherichia coli K12 (see 6 papers)
    28% identity, 99% coverage of query (143 bits)

GsiC / b0831 glutathione ABC transporter membrane subunit GsiC (EC 7.4.2.10) from Escherichia coli K-12 substr. MG1655 (see 2 papers)
gsiC / P75798 glutathione ABC transporter membrane subunit GsiC (EC 7.4.2.10) from Escherichia coli (strain K12) (see paper)
GSIC_ECOLI / P75798 Glutathione transport system permease protein GsiC from Escherichia coli (strain K12) (see 2 papers)
P75798 ABC-type glutathione transporter (EC 7.4.2.10) from Escherichia coli (see paper)
TC 3.A.1.5.11 / P75798 Inner membrane ABC transporter permease protein yliC, component of Glutathione porter, YliABCD or GsiABCD from Escherichia coli (see 5 papers)
gsiC / GB|ABE06320.1 glutathione ABC transporter, permease protein GsiC from Escherichia coli K12 (see paper)
    30% identity, 99% coverage of query (143 bits)

TC 3.A.1.5.2 / P26903 DppB aka DCIAB, component of Dipeptide porter. Also transports δ-aminolevulinic acid (ALA) and heme from Bacillus subtilis (see 2 papers)
    27% identity, 99% coverage of query (142 bits)

OPPB_BACSU / P24138 Oligopeptide transport system permease protein OppB; Stage 0 sporulation protein KB from Bacillus subtilis (strain 168) (see 2 papers)
    32% identity, 99% coverage of query (142 bits)

TC 3.A.1.5.18 / O31307 OppB1, component of The oligopeptide transporter OppA1-5, B1, C1, DF (functions with five binding proteins of differing induction properties and peptide specificities; OppA1-3 are chromosomally encoded; OppA4 and 5 are plasmid encoded.) from Borrelia burgdorferi (Lyme disease spirochete) (see 2 papers)
    30% identity, 98% coverage of query (141 bits)

TC 3.A.1.5.27 / P45096 Dipeptide transport system permease protein dppB, component of The glutathione uptake porter, DppBCDF with the glutathione binding protein, DppA (GbpA; HbpA). Takes up reduced (GSH) and oxidized (GSSG) but not bulky glutathione S conjugates or glutathione derivatives with C-terminal modifications from Haemophilus influenzae (see 2 papers)
    29% identity, 98% coverage of query (135 bits)

TC 3.A.1.5.10 / P0A4N7 OppB, component of Oligopeptide porter (transports peptides of 4-35) amino acyl residues; di- and tripeptides are not transported; hydrophobic basic peptides are preferred). OppA determines the specificity of the system (Doeven et al., 2004). A large cavity in OppA binds proline-rich peptides preferentially (Berntsson et al., 2009). Two crystal structures of OppA with different nonapeptides show binding in different registers from Lactococcus lactis subsp. lactis (Streptococcus lactis) (see 2 papers)
    29% identity, 98% coverage of query (126 bits)

Q73NS9 ABC-type dipeptide transporter (EC 7.4.2.9) from Treponema denticola (see paper)
    31% identity, 84% coverage of query (125 bits)

TC 3.A.1.5.19 / Q2FZR7 OppB, component of The major oligopeptide uptake porter, Opp-3 (of four paralogues, this is the only one that mediates nitrogen nutrition from Staphylococcus aureus (strain NCTC 8325)
    27% identity, 98% coverage of query (123 bits)

TC 3.A.1.5.16 / Q9WXN7 TM0030, component of β-glucoside porter (Conners et al., 2005). Binds cellobiose, laminaribiose (Nanavati et al. 2006). Regulated by cellobiose-responsive repressor BglR (see paper)
    26% identity, 98% coverage of query (121 bits)

Q9ZAS5 ABC-type dipeptide transporter (EC 7.4.2.9) from Streptococcus pyogenes (see paper)
    29% identity, 79% coverage of query (117 bits)

NikB / b3477 Ni(2+) ABC transporter membrane subunit NikB from Escherichia coli K-12 substr. MG1655 (see 3 papers)
nikB / P33591 nickel ABC transporter membrane subunit NikB from Escherichia coli (strain K12) (see paper)
TC 3.A.1.5.3 / P33591 NikB aka B3477, component of Nickel porter from Escherichia coli (see 5 papers)
    26% identity, 98% coverage of query (115 bits)

TC 3.A.1.5.40 / Q7VJ34 Nickel transport system permease protein NikB, component of Nickel uptake porter, NikAB(CD)E from Helicobacter hepaticus (strain ATCC 51449 / 3B1)
    28% identity, 78% coverage of query (115 bits)

TC 3.A.1.5.25 / Q9CIL1 Oligopeptide ABC trasporter permease protein, component of The ABC peptide/signalling peptide transporter. OptA binds peptides of 3-6 aas; OptS binds dipeptides. OptB,C,D are most similar to 3.A.1.5.19 from Lactococcus lactis subsp. lactis (see paper)
    25% identity, 82% coverage of query (114 bits)

TC 3.A.1.5.12 / Q9X0F6 TM1066, component of Probable rhamnose oligosaccharide porter. Induced by rhamnose (see paper)
    30% identity, 98% coverage of query (112 bits)

DPPB_LACLM / A2RI75 Dipeptide transport system permease protein DppB from Lactococcus lactis subsp. cremoris (strain MG1363) (see paper)
    25% identity, 82% coverage of query (111 bits)

TC 3.A.1.5.29 / Q9WXR6 ABC-type transporter, integral membrane subunit, component of Probable xylan oligosaccharide porter (Conners et al. 2005). Induced by cylan and xylose. Regulated by xylose-responsive regulator XylR from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
    27% identity, 99% coverage of query (105 bits)

SM_b21646 ABC transporter for D-Raffinose, permease component 2 from Sinorhizobium meliloti 1021
    28% identity, 98% coverage of query (102 bits)

TC 3.A.1.5.4 / O30543 AccD, component of Agrocinopine (an opine)/Agrocin 84 (an antibiotic) porter from Agrobacterium radiobacter (see 3 papers)
    28% identity, 84% coverage of query (100 bits)

CNTB_STAA8 / Q2FVE8 Metal-staphylopine import system permease protein CntB from Staphylococcus aureus (strain NCTC 8325 / PS 47) (see 2 papers)
TC 3.A.1.5.43 / Q2FVE8 Peptide ABC transporter, permease protein, putative, component of The metal-staphylopine (nicotianamine-like metalophore) complex uptake system, CntABCDF from Staphylococcus aureus (strain NCTC 8325)
    24% identity, 99% coverage of query (97.8 bits)

NIKB_STAA8 / Q2FYQ5 Nickel import system permease protein NikB from Staphylococcus aureus (strain NCTC 8325 / PS 47) (see paper)
    24% identity, 97% coverage of query (97.8 bits)

CNTB_STAAM / A0A0H3K104 Metal-staphylopine import system permease protein CntB from Staphylococcus aureus (strain Mu50 / ATCC 700699) (see paper)
    24% identity, 99% coverage of query (97.1 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory