Searching for up to 100 curated homologs for PfGW456L13_2986 FitnessBrowser__pseudo13_GW456_L13:PfGW456L13_2986 (356 a.a.)
Found high-coverage hits (≥70%) to 20 curated proteins.
Removed hits that are identical to the query, leaving 19
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
Pf1N1B4_4790 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) from Pseudomonas fluorescens FW300-N1B4
90% identity, 100% coverage of query (628 bits)
PS417_13835 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) from Pseudomonas simiae WCS417
86% identity, 99% coverage of query (628 bits)
AO353_25665 3-hydroxy-isobutyryl-CoA hydrolase (EC 3.1.2.4) from Pseudomonas fluorescens FW300-N2E3
88% identity, 100% coverage of query (627 bits)
Psest_2439 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) from Pseudomonas stutzeri RCH2
65% identity, 99% coverage of query (447 bits)
RR42_RS28545 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) from Cupriavidus basilensis FW507-4G11
49% identity, 96% coverage of query (294 bits)
Hibch / Q5XIE6 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) from Rattus norvegicus (see 5 papers)
HIBCH_RAT / Q5XIE6 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; 3-hydroxyisobutyryl-coenzyme A hydrolase; HIB-CoA hydrolase; HIBYL-CoA-H; EC 3.1.2.4 from Rattus norvegicus (Rat) (see 2 papers)
40% identity, 97% coverage of query (258 bits)
bch / Q81DR3 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) from Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG 7414 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NCTC 2599 / NRRL B-3711) (see paper)
Q81DR3 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) from Bacillus cereus (see paper)
36% identity, 97% coverage of query (258 bits)
HIBCH_HUMAN / Q6NVY1 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; 3-hydroxyisobutyryl-coenzyme A hydrolase; HIB-CoA hydrolase; HIBYL-CoA-H; EC 3.1.2.4 from Homo sapiens (Human) (see 2 papers)
37% identity, 98% coverage of query (239 bits)
3bptA / Q6NVY1 Crystal structure of human beta-hydroxyisobutyryl-coa hydrolase in complex with quercetin
36% identity, 98% coverage of query (237 bits)
echA9 / O53419 steroid enoyl-CoA hydratase from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
40% identity, 99% coverage of query (230 bits)
4hdtA / G7CC99 Crystal structure of a carnitinyl-coa dehydratase from mycobacterium thermoresistibile (see paper)
39% identity, 98% coverage of query (214 bits)
HIBC1_ARATH / Q9LKJ1 3-hydroxyisobutyryl-CoA hydrolase 1; CoA-thioester hydrolase CHY1; EC 3.1.2.-; EC 3.1.2.4 from Arabidopsis thaliana (Mouse-ear cress) (see 5 papers)
Q9LKJ1 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) from Arabidopsis thaliana (see paper)
34% identity, 99% coverage of query (211 bits)
PGA1_c17350 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) from Phaeobacter inhibens BS107
39% identity, 90% coverage of query (199 bits)
HIBCH_NEUCR / Q1K7A4 Small ribosomal subunit protein mS47; 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; 3-hydroxyisobutyryl-coenzyme A hydrolase; HIB-CoA hydrolase; HIBYL-CoA-H; EC 3.1.2.4 from Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) (see paper)
34% identity, 93% coverage of query (199 bits)
Q9SE41 enoyl-CoA hydratase (EC 4.2.1.17) from Avicennia marina (see paper)
33% identity, 90% coverage of query (191 bits)
C3KM96 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) from Sinorhizobium fredii (see paper)
39% identity, 92% coverage of query (174 bits)
EHD3 / Q5AI24 3-hydroxypropanonyl-CoA hydrolase (EC 3.1.2.4) from Candida albicans (strain SC5314 / ATCC MYA-2876) (see paper)
30% identity, 92% coverage of query (172 bits)
Build an alignment for PfGW456L13_2986 and 17 homologs with ≥ 30% identity
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HIBCH_YEAST / P28817 Small ribosomal subunit protein mS47; 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; 3-hydroxyisobutyryl-coenzyme A hydrolase; HIB-CoA hydrolase; HIBYL-CoA-H; EC 3.1.2.4 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 7 papers)
28% identity, 90% coverage of query (147 bits)
H16_A3593 / Q0K5S0 enoyl-CoA hydratase (EC 4.2.1.17) from Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337) (see paper)
28% identity, 77% coverage of query (90.1 bits)
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Lawrence Berkeley National Laboratory