Searching for up to 100 curated homologs for PfGW456L13_3001 FitnessBrowser__pseudo13_GW456_L13:PfGW456L13_3001 (326 a.a.)
Found high-coverage hits (≥70%) to 68 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
A9H324 phosphogluconate dehydrogenase (NAD+-dependent, decarboxylating) (EC 1.1.1.343) from Gluconacetobacter diazotrophicus (see paper)
65% identity, 99% coverage of query (435 bits)
6PGDH_GLUOX / G5EBD7 6-phosphogluconate dehydrogenase, NAD(+)-dependent, decarboxylating; 6PGDH; EC 1.1.1.343 from Gluconobacter oxydans (strain 621H) (Gluconobacter suboxydans) (see paper)
G5EBD7 phosphogluconate dehydrogenase (NAD+-dependent, decarboxylating) (EC 1.1.1.343) from Gluconobacter oxydans (see paper)
63% identity, 99% coverage of query (425 bits)
6vpbB / A9H324 A novel membrane-bound 6-phosphogluconate dehydrogenase from the acetic acid bacteria gluconacetobacter diazotrophicus (gd6pgd) (see paper)
65% identity, 97% coverage of query (423 bits)
Q2RIZ2 phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) (EC 1.1.1.44) from Moorella thermoacetica (see paper)
45% identity, 98% coverage of query (278 bits)
A0A1J5NX54 phosphogluconate dehydrogenase (NAD+-dependent, decarboxylating) (EC 1.1.1.343); phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) (EC 1.1.1.44) from Moorella thermoacetica (see paper)
44% identity, 98% coverage of query (275 bits)
6PGD_HALVD / D4GST8 6-phosphogluconate dehydrogenase, NAD(+)-dependent, decarboxylating; 6PGDH; EC 1.1.1.343 from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see paper)
D4GST8 phosphogluconate dehydrogenase (NAD+-dependent, decarboxylating) (EC 1.1.1.343) from Haloferax volcanii (see paper)
37% identity, 100% coverage of query (196 bits)
2w90B Geobacillus stearothermophilus 6-phosphogluconate dehydrogenase with bound 6- phosphogluconate (see paper)
34% identity, 91% coverage of query (188 bits)
6PGDH_BACSU / P12013 6-phosphogluconate dehydrogenase, NAD(+)-dependent, decarboxylating; EC 1.1.1.343 from Bacillus subtilis (strain 168) (see paper)
P12013 phosphogluconate dehydrogenase (NAD+-dependent, decarboxylating) (EC 1.1.1.343) from Bacillus subtilis (see paper)
35% identity, 91% coverage of query (182 bits)
gndA / P80859 6-phosphogluconate dehydrogenase (decarboxylating) (EC 1.1.1.44) from Bacillus subtilis (strain 168) (see paper)
6PGD_BACSU / P80859 6-phosphogluconate dehydrogenase, NADP(+)-dependent, decarboxylating; GNTZII; EC 1.1.1.44 from Bacillus subtilis (strain 168) (see paper)
P80859 phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) (EC 1.1.1.44) from Bacillus subtilis (see paper)
34% identity, 91% coverage of query (179 bits)
8i4qA / Q8NQI2 Crystal structure of 6-phosphogluconate dehydrogenase from corynebacterium glutamicum (see paper)
33% identity, 95% coverage of query (177 bits)
P96789 phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) (EC 1.1.1.44) from Lactococcus lactis (see paper)
33% identity, 98% coverage of query (174 bits)
P96789 6-phosphogluconate dehydrogenase, decarboxylating; EC 1.1.1.44 from Lactococcus lactis subsp. cremoris (strain MG1363)
33% identity, 98% coverage of query (174 bits)
Q6NHC5 phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) (EC 1.1.1.44) from Corynebacterium glutamicum (see paper)
33% identity, 91% coverage of query (173 bits)
2iz1B / P96789 6pdh complexed with pex inhibitor synchrotron data (see paper)
33% identity, 98% coverage of query (173 bits)
2iypB Product rup
33% identity, 98% coverage of query (173 bits)
2iypA Product rup
33% identity, 98% coverage of query (173 bits)
2iyoA Structural characterization of a bacterial 6pdh reveals aspects of specificity, mechanism and mode of inhibition
33% identity, 98% coverage of query (173 bits)
6PGD1_SPIOL / Q94KU1 6-phosphogluconate dehydrogenase, decarboxylating 1; EC 1.1.1.44 from Spinacia oleracea (Spinach) (see paper)
35% identity, 99% coverage of query (172 bits)
6PGD2_ARATH / Q9FWA3 6-phosphogluconate dehydrogenase, decarboxylating 2; EC 1.1.1.44 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q9FWA3 phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) (EC 1.1.1.44) from Arabidopsis thaliana (see 2 papers)
34% identity, 98% coverage of query (167 bits)
3fwnA / P00350 Dimeric 6-phosphogluconate dehydrogenase complexed with 6- phosphogluconate and 2'-monophosphoadenosine-5'-diphosphate (see paper)
33% identity, 95% coverage of query (167 bits)
Gnd / b2029 6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44) from Escherichia coli K-12 substr. MG1655 (see 66 papers)
gnd / P00350 6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44) from Escherichia coli (strain K12) (see 64 papers)
6PGD_ECOLI / P00350 6-phosphogluconate dehydrogenase, decarboxylating; EC 1.1.1.44 from Escherichia coli (strain K12) (see paper)
P00350 phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) (EC 1.1.1.44) from Escherichia coli (see paper)
33% identity, 95% coverage of query (167 bits)
2zydA Dimeric 6-phosphogluconate dehydrogenase complexed with glucose
33% identity, 95% coverage of query (167 bits)
3fwnB Dimeric 6-phosphogluconate dehydrogenase complexed with 6- phosphogluconate and 2'-monophosphoadenosine-5'-diphosphate
33% identity, 95% coverage of query (167 bits)
P52208 phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) (EC 1.1.1.44) from Synechocystis sp. (see paper)
35% identity, 91% coverage of query (166 bits)
Q762L5 phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) (EC 1.1.1.44) from Klebsiella pneumoniae (see paper)
33% identity, 95% coverage of query (166 bits)
gnd / AAA21136.1 phosphogluconate dehydrogenase from Escherichia coli (see paper)
33% identity, 95% coverage of query (165 bits)
6PGD2_YEAST / P53319 6-phosphogluconate dehydrogenase, decarboxylating 2; EC 1.1.1.44 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
P53319 phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) (EC 1.1.1.44) from Saccharomyces cerevisiae (see paper)
34% identity, 91% coverage of query (162 bits)
6PGD1_ORYSJ / Q9LI00 6-phosphogluconate dehydrogenase, decarboxylating 1; OsG6PGH1; EC 1.1.1.44 from Oryza sativa subsp. japonica (Rice) (see paper)
Q9LI00 phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) (EC 1.1.1.44) from Oryza sativa Japonica Group (see paper)
33% identity, 96% coverage of query (161 bits)
7cb5B / A0A0H3KGN1 The 6-phosphogluconate dehydrogenase from staphylococcus aureus (6- phosphogluconate bound) (see paper)
33% identity, 91% coverage of query (161 bits)
7cb2A The 6-phosphogluconate dehydrogenase (NADP-bound) from staphylococcus aureus
33% identity, 91% coverage of query (161 bits)
Q9WYR9 phosphogluconate dehydrogenase (NAD+-dependent, decarboxylating) (EC 1.1.1.343); phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) (EC 1.1.1.44) from Thermotoga maritima (see 2 papers)
33% identity, 90% coverage of query (158 bits)
6PGD2_ORYSJ / Q2R480 6-phosphogluconate dehydrogenase, decarboxylating 2, chloroplastic; OsG6PGH2; EC 1.1.1.44 from Oryza sativa subsp. japonica (Rice)
34% identity, 91% coverage of query (156 bits)
P78812 phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) (EC 1.1.1.44) from Schizosaccharomyces pombe (see paper)
SPBC660.16 / RF|NP_595095.1 phosphogluconate dehydrogenase, decarboxylating; EC 1.1.1.44 from Schizosaccharomyces pombe (see 3 papers)
35% identity, 91% coverage of query (155 bits)
P78812 6-phosphogluconate dehydrogenase, decarboxylating; EC 1.1.1.44 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
35% identity, 91% coverage of query (155 bits)
6PGD2_SPIOL / Q94KU2 6-phosphogluconate dehydrogenase, decarboxylating 2, chloroplastic; EC 1.1.1.44 from Spinacia oleracea (Spinach) (see paper)
34% identity, 91% coverage of query (154 bits)
6PGD1_ARATH / Q9SH69 6-phosphogluconate dehydrogenase, decarboxylating 1, chloroplastic; EC 1.1.1.44 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q9SH69 phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) (EC 1.1.1.44) from Arabidopsis thaliana (see paper)
32% identity, 91% coverage of query (154 bits)
6PGD3_ARATH / Q9FFR3 6-phosphogluconate dehydrogenase, decarboxylating 3, chloroplastic; EC 1.1.1.44 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q9FFR3 phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) (EC 1.1.1.44) from Arabidopsis thaliana (see paper)
34% identity, 91% coverage of query (154 bits)
GND1 6-phosphogluconate dehydrogenase, decarboxylating; EC 1.1.1.44 from Candida albicans (see paper)
33% identity, 91% coverage of query (148 bits)
6PGD_AGGAC / P70718 6-phosphogluconate dehydrogenase, decarboxylating; EC 1.1.1.44 from Aggregatibacter actinomycetemcomitans (Actinobacillus actinomycetemcomitans) (Haemophilus actinomycetemcomitans) (see paper)
33% identity, 99% coverage of query (148 bits)
6PGD1_YEAST / P38720 6-phosphogluconate dehydrogenase, decarboxylating 1; EC 1.1.1.44 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 3 papers)
P38720 phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) (EC 1.1.1.44) from Saccharomyces cerevisiae (see 2 papers)
33% identity, 91% coverage of query (147 bits)
2p4qA / P38720 Crystal structure analysis of gnd1 in saccharomyces cerevisiae (see paper)
33% identity, 91% coverage of query (147 bits)
Q6WAT5 phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) (EC 1.1.1.44) from Trypanosoma cruzi (see paper)
31% identity, 91% coverage of query (140 bits)
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Q8IKT2 phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) (EC 1.1.1.44) from Plasmodium falciparum (see paper)
6fqyA / Q8IKT2 Plasmodium falciparum 6-phosphogluconate dehydrogenase in its apo form, in complex with its cofactor NADP+ and in complex with its substrate 6-phosphogluconate (see paper)
29% identity, 94% coverage of query (140 bits)
6fqzA Plasmodium falciparum 6-phosphogluconate dehydrogenase in its apo form, in complex with its cofactor NADP+ and in complex with its substrate 6-phosphogluconate
29% identity, 94% coverage of query (140 bits)
8c79A / Q18L02 Crystal structure of leishmania donovani 6-phosphogluconate dehydrogenase complexed with NADPH (see paper)
31% identity, 90% coverage of query (138 bits)
A0A0D1CRJ9 phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) (EC 1.1.1.44) from Ustilago maydis (see paper)
34% identity, 94% coverage of query (138 bits)
PGD / P52209 6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44) from Homo sapiens (see paper)
6PGD_HUMAN / P52209 6-phosphogluconate dehydrogenase, decarboxylating; EC 1.1.1.44 from Homo sapiens (Human)
P52209 phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) (EC 1.1.1.44) from Homo sapiens (see 9 papers)
32% identity, 97% coverage of query (137 bits)
2jkvA / P52209 Structure of human phosphogluconate dehydrogenase in complex with NADPH at 2.53a
32% identity, 97% coverage of query (137 bits)
5uq9E Crystal structure of 6-phosphogluconate dehydrogenase with ((4r,5r)-5- (hydroxycarbamoyl)-2,2-dimethyl-1,3-dioxolan-4-yl)methyl dihydrogen phosphate
32% identity, 97% coverage of query (137 bits)
6Pgd / CAD56883.1 6-phosphogluconic dehydrogenase from Bactrocera oleae (see paper)
33% identity, 91% coverage of query (135 bits)
Q9DCD0 phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) (EC 1.1.1.44) from Mus musculus (see paper)
32% identity, 91% coverage of query (132 bits)
6PGD_RAT / P85968 6-phosphogluconate dehydrogenase, decarboxylating; EC 1.1.1.44 from Rattus norvegicus (Rat) (see paper)
P85968 phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) (EC 1.1.1.44) from Rattus norvegicus (see 2 papers)
32% identity, 91% coverage of query (131 bits)
6PGD_SHEEP / P00349 6-phosphogluconate dehydrogenase, decarboxylating; EC 1.1.1.44 from Ovis aries (Sheep) (see 2 papers)
32% identity, 91% coverage of query (124 bits)
1pgqA Crystallographic study of coenzyme, coenzyme analogue and substrate binding in 6-phosphogluconate dehydrogenase: implications for NADP specificity and the enzyme mechanism
32% identity, 91% coverage of query (124 bits)
1pgpA Crystallographic study of coenzyme, coenzyme analogue and substrate binding in 6-phosphogluconate dehydrogenase: implications for NADP specificity and the enzyme mechanism
32% identity, 91% coverage of query (124 bits)
1pgoA Crystallographic study of coenzyme, coenzyme analogue and substrate binding in 6-phosphogluconate dehydrogenase: implications for NADP specificity and the enzyme mechanism
32% identity, 91% coverage of query (124 bits)
1pgnA Crystallographic study of coenzyme, coenzyme analogue and substrate binding in 6-phosphogluconate dehydrogenase: implications for NADP specificity and the enzyme mechanism
32% identity, 91% coverage of query (124 bits)
6PGD_TRYBB / P31072 6-phosphogluconate dehydrogenase, decarboxylating; EC 1.1.1.44 from Trypanosoma brucei brucei (see paper)
30% identity, 87% coverage of query (120 bits)
MMSB_PSEAE / P28811 3-hydroxyisobutyrate dehydrogenase; HIBADH; EC 1.1.1.31 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
mmsB / AAA25892.1 3-hydroxyisobutyrate dehydrogenase from Pseudomonas aeruginosa (see paper)
26% identity, 90% coverage of query (64.3 bits)
3w6zA / A3MU08 Crystal structure of NADP bound l-serine 3-dehydrogenase (k170m) from hyperthermophilic archaeon pyrobaculum calidifontis (see paper)
25% identity, 94% coverage of query (62.4 bits)
3ws7A The 1.18 a resolution structure of l-serine 3-dehydrogenase complexed with NADP+ and sulfate ion from the hyperthermophilic archaeon pyrobaculum calidifontis
24% identity, 94% coverage of query (60.8 bits)
3obbA / Q9I5I6 Crystal structure of a possible 3-hydroxyisobutyrate dehydrogenase from pseudomonas aeruginosa pao1 (see paper)
25% identity, 73% coverage of query (51.6 bits)
3q3cA Crystal structure of a serine dehydrogenase from pseudomonas aeruginosa pao1 in complex with NAD
25% identity, 73% coverage of query (49.3 bits)
SERDH_PSEAE / Q9I5I6 NAD-dependent L-serine dehydrogenase; L-serine 3-dehydrogenase (NAD(+)); EC 1.1.1.387 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
Q9I5I6 L-serine 3-dehydrogenase (NAD+) (EC 1.1.1.387) from Pseudomonas aeruginosa (see paper)
25% identity, 76% coverage of query (49.3 bits)
6smyA Crystal structure of sla reductase yihu from e. Coli with nadh and product dhps
24% identity, 92% coverage of query (45.8 bits)
6smzC / P0A9V8 Crystal structure of sla reductase yihu from e. Coli in complex with nadh
24% identity, 92% coverage of query (45.8 bits)
SquU / b3882 3-sulfolactaldehyde reductase (EC 1.1.1.373; EC 1.1.1.61) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
yihU / P0A9V8 3-sulfolactaldehyde reductase (EC 1.1.1.373; EC 1.1.1.61) from Escherichia coli (strain K12) (see 3 papers)
SQUU_ECOLI / P0A9V8 3-sulfolactaldehyde reductase; SLA reductase; 4-hydroxybutyrate dehydrogenase; Gamma-hydroxybutyrate dehydrogenase; GHBDH; Succinic semialdehyde reductase; SSA reductase; EC 1.1.1.373; EC 1.1.1.61 from Escherichia coli (strain K12) (see 2 papers)
P0A9V8 sulfolactaldehyde 3-reductase (EC 1.1.1.373); 4-hydroxybutyrate dehydrogenase (EC 1.1.1.61) from Escherichia coli (see 2 papers)
24% identity, 92% coverage of query (45.8 bits)
5je8B / Q81DR6 The crystal structure of bacillus cereus 3-hydroxyisobutyrate dehydrogenase in complex with NAD (see paper)
22% identity, 95% coverage of query (43.5 bits)
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