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Searching for up to 100 curated homologs for PfGW456L13_3320 L-arabonate dehydratase (EC 4.2.1.25) (578 a.a.)

Found high-coverage hits (≥70%) to 42 curated proteins.

Removed hits that are identical to the query, leaving 41

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

AO356_24585 L-arabonate dehydratase (EC 4.2.1.25) from Pseudomonas fluorescens FW300-N2C3
    97% identity, 100% coverage of query (1165 bits)

PS417_11000 L-arabonate dehydratase (EC 4.2.1.25) from Pseudomonas simiae WCS417
    97% identity, 100% coverage of query (1159 bits)

Pf6N2E2_609 L-arabonate dehydratase (EC 4.2.1.25) from Pseudomonas fluorescens FW300-N2E2
    97% identity, 100% coverage of query (1158 bits)

HSERO_RS05205 L-arabonate dehydratase (EC 4.2.1.25) from Herbaspirillum seropedicae SmR1
    81% identity, 100% coverage of query (978 bits)

ARADA_AZOBR / Q1JUQ1 L-arabonate dehydratase; L-arabinonate dehydratase; EC 4.2.1.25 from Azospirillum brasilense (see paper)
    80% identity, 100% coverage of query (954 bits)

Shewana3_2070 L-arabonate dehydratase (EC 4.2.1.25) from Shewanella sp. ANA-3
    74% identity, 100% coverage of query (880 bits)

BPHYT_RS19730 L-arabonate dehydratase (EC 4.2.1.25) from Burkholderia phytofirmans PsJN
    67% identity, 99% coverage of query (789 bits)

SM_b20890 L-arabonate dehydratase (EC 4.2.1.25) from Sinorhizobium meliloti 1021
    67% identity, 99% coverage of query (788 bits)

ARAD_RHILW / B5ZZ34 L-arabinonate dehydratase; ArDHT; D-fuconate dehydratase; Galactonate dehydratase; L-arabonate dehydratase; EC 4.2.1.25; EC 4.2.1.67; EC 4.2.1.6 from Rhizobium leguminosarum bv. trifolii (strain WSM2304) (see 2 papers)
I9XDU6 L-Arabinonate dehydratase (EC 4.2.1.25) from Rhizobium leguminosarum bv. trifolii (see 2 papers)
    65% identity, 99% coverage of query (757 bits)

8epzA / A0A4R3LQ44 Crystal structure of fe-s cluster-dependent dehydratase from paralcaligenes ureilyticus in complex with mn
    65% identity, 99% coverage of query (756 bits)

5j85A / I9XDU6 Ser480ala mutant of l-arabinonate dehydratase (see paper)
    64% identity, 99% coverage of query (756 bits)

8ej0A Dihydroxyacid dehydratase
    65% identity, 99% coverage of query (754 bits)

ILVD1_RHIME / Q92RP0 Putative dehydratase IlvD1; EC 4.2.1.- from Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti) (see paper)
    64% identity, 100% coverage of query (734 bits)

SGD_PSEPU / P0DOV7 6-deoxy-6-sulfo-D-gluconate dehydratase; SG dehydratase; EC 4.2.1.162 from Pseudomonas putida (Arthrobacter siderocapsulatus) (see paper)
    47% identity, 97% coverage of query (500 bits)

7m3kA / Q2YJ21 Crystal structure of galactonate dehydratase from brucella melitensis biovar abortus 2308
    48% identity, 93% coverage of query (469 bits)

Pf6N2E2_1668 Xylonate dehydratase (EC 4.2.1.82) from Pseudomonas fluorescens FW300-N2E2
    43% identity, 100% coverage of query (439 bits)

AO356_28760 Xylonate dehydratase (EC 4.2.1.82) from Pseudomonas fluorescens FW300-N2C3
    43% identity, 100% coverage of query (435 bits)

xylD / A0A0H3C6H6 xylonate dehydratase monomer (EC 4.2.1.82) from Caulobacter vibrioides (strain NA1000 / CB15N) (see paper)
CCNA_00862 Xylonate dehydratase (EC 4.2.1.82) from Caulobacter crescentus NA1000
    42% identity, 100% coverage of query (420 bits)

XYLD_CAUVC / Q9A9Z2 D-xylonate dehydratase; XyDHT; Gluconate dehydratase; EC 4.2.1.82; EC 4.2.1.39 from Caulobacter vibrioides (strain ATCC 19089 / CB15) (Caulobacter crescentus) (see 3 papers)
Q9A9Z2 xylonate dehydratase (EC 4.2.1.82) from Caulobacter vibrioides (see 2 papers)
    41% identity, 100% coverage of query (419 bits)

5oynA / Q9A9Z2 Crystal structure of d-xylonate dehydratase in holo-form (see paper)
    42% identity, 99% coverage of query (417 bits)

ilvDD / O27498 dihydroxy-acid dehydratase subunit (EC 4.2.1.9) from Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) (see 4 papers)
    39% identity, 91% coverage of query (340 bits)

ILVD_MYCTU / P9WKJ5 Dihydroxy-acid dehydratase; DAD; EC 4.2.1.9 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
    39% identity, 93% coverage of query (317 bits)

6ovtA / P9WKJ5 Crystal structure of ilvd from mycobacterium tuberculosis (see paper)
    39% identity, 93% coverage of query (317 bits)

Q97UB2 dihydroxy-acid dehydratase (EC 4.2.1.9) from Saccharolobus solfataricus (see 2 papers)
    35% identity, 93% coverage of query (314 bits)

5ze4A / Q9LIR4 The structure of holo- structure of dhad complex with [2fe-2s] cluster (see paper)
    34% identity, 93% coverage of query (284 bits)

ILVD_ARATH / Q9LIR4 Dihydroxy-acid dehydratase, chloroplastic; AthDHAD; DAD; EC 4.2.1.9 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Q9LIR4 dihydroxy-acid dehydratase (EC 4.2.1.9) from Arabidopsis thaliana (see 2 papers)
    34% identity, 93% coverage of query (283 bits)

salH / B0L7G4 dihydroxy-acid dehydratase from Salinispora tropica (see paper)
    35% identity, 90% coverage of query (276 bits)

Q0K7F8 dihydroxy-acid dehydratase (EC 4.2.1.9) from Cupriavidus necator (see paper)
ilvD / Q0K7F8 dihydroxyacid dehydratase (EC 4.2.1.9) from Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337) (see paper)
    36% identity, 89% coverage of query (271 bits)

ILVC_ASPFU / Q4X099 Dihydroxy-acid dehydratase ilvC, mitochondrial; DHAD ilvC; EC 4.2.1.9 from Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata) (see paper)
    32% identity, 90% coverage of query (266 bits)

ILV3_YEAST / P39522 Dihydroxy-acid dehydratase, mitochondrial; DAD; EC 4.2.1.9 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 13 papers)
    32% identity, 90% coverage of query (250 bits)

ILVD_CAUVC / P55186 Dihydroxy-acid dehydratase; DAD; EC 4.2.1.9 from Caulobacter vibrioides (strain ATCC 19089 / CB15) (Caulobacter crescentus) (see paper)
    31% identity, 88% coverage of query (228 bits)

ILVD_RHIL3 / Q1MIB2 Dihydroxy-acid dehydratase; DAD; EC 4.2.1.9 from Rhizobium leguminosarum bv. viciae (strain 3841) (see paper)
    31% identity, 88% coverage of query (226 bits)

Q8NQZ9 dihydroxy-acid dehydratase (EC 4.2.1.9) from Corynebacterium glutamicum (see 2 papers)
    30% identity, 94% coverage of query (224 bits)

IlvD / b3771 dihydroxy-acid dehydratase (EC 4.2.1.9) from Escherichia coli K-12 substr. MG1655 (see paper)
ILVD_ECOLI / P05791 Dihydroxy-acid dehydratase; DAD; EC 4.2.1.9 from Escherichia coli (strain K12) (see 4 papers)
ilvD / P05791 dihydroxy-acid dehydratase (EC 4.2.1.9) from Escherichia coli (strain K12) (see 14 papers)
ilvD / EW|b3771 dihydroxyacid dehydratase from Escherichia coli K12 (see 2 papers)
    30% identity, 91% coverage of query (219 bits)

edd / CAE53634.1 6-phosphogluconate dehydratase from Nonomuraea gerenzanensis (see paper)
    30% identity, 93% coverage of query (190 bits)

Build an alignment

Build an alignment for PfGW456L13_3320 and 35 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

Q1PAG1 phosphogluconate dehydratase (EC 4.2.1.12) from Pseudomonas chlororaphis (see paper)
    28% identity, 88% coverage of query (177 bits)

YjhG / b4297 KpLE2 phage-like element; D-xylonate dehydratase (EC 4.2.1.82) from Escherichia coli K-12 substr. MG1655 (see 8 papers)
YJHG_ECOLI / P39358 D-xylonate dehydratase YjhG; EC 4.2.1.82 from Escherichia coli (strain K12) (see 2 papers)
P39358 xylonate dehydratase (EC 4.2.1.82) from Escherichia coli (see paper)
yjhG / P39358 KpLE2 phage-like element; D-xylonate dehydratase (EC 4.2.1.82) from Escherichia coli (strain K12) (see 7 papers)
yjhG / RF|NP_418717 uncharacterized protein yjhG from Escherichia coli K12 (see paper)
    33% identity, 73% coverage of query (176 bits)

EDD_ZYMMO / P21909 Phosphogluconate dehydratase; 6-phosphogluconate dehydratase; EC 4.2.1.12 from Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) (see paper)
    29% identity, 84% coverage of query (167 bits)

Edd / b1851 phosphogluconate dehydratase (EC 4.2.1.12) from Escherichia coli K-12 substr. MG1655 (see 30 papers)
EDD_ECOLI / P0ADF6 Phosphogluconate dehydratase; 6-phosphogluconate dehydratase; Entner-Doudoroff dehydrase; EC 4.2.1.12 from Escherichia coli (strain K12) (see 4 papers)
edd / P0ADF6 phosphogluconate dehydratase (EC 4.2.1.12) from Escherichia coli (strain K12) (see 29 papers)
edd / RF|NP_416365 phosphogluconate dehydratase from Escherichia coli K12 (see 2 papers)
    28% identity, 88% coverage of query (167 bits)

YagF / b0269 CP4-6 prophage; D-xylonate dehydratase (EC 4.2.1.82) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
YAGF_ECOLI / P77596 D-xylonate dehydratase YagF; EC 4.2.1.82 from Escherichia coli (strain K12) (see 2 papers)
yagF / P77596 CP4-6 prophage; D-xylonate dehydratase (EC 4.2.1.82) from Escherichia coli (strain K12) (see 4 papers)
    33% identity, 71% coverage of query (165 bits)

edd / AAA23722.1 6-phosphogluconate dehydratase from Escherichia coli (see paper)
    28% identity, 88% coverage of query (162 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory