Searching for up to 100 curated homologs for PfGW456L13_3525 FitnessBrowser__pseudo13_GW456_L13:PfGW456L13_3525 (243 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
LNRL_BACSU / P94440 Linearmycin resistance ATP-binding protein LnrL; EC 7.6.2.- from Bacillus subtilis (strain 168) (see 2 papers)
33% identity, 98% coverage of query (149 bits)
4yerA / Q9X1C3 Crystal structure of an abc transporter atp-binding protein (tm_1403) from thermotoga maritima msb8 at 2.35 a resolution
35% identity, 89% coverage of query (148 bits)
YadG / b0127 putative ABC transporter ATP-binding protein YadG from Escherichia coli K-12 substr. MG1655 (see 7 papers)
YADG_ECOLI / P36879 Uncharacterized ABC transporter ATP-binding protein YadG from Escherichia coli (strain K12) (see paper)
yadG / MB|P36879 uncharacterized ABC transporter ATP-binding protein yadG from Escherichia coli K12 (see paper)
38% identity, 88% coverage of query (135 bits)
TC 3.A.1.130.1 / Q9X432 ABC transporter homolog CylA, component of The multidrug/hemolysin exporter, CylA/B (note: CylK (AAF01071) may influence its activity)(Gottschalk et al., 2006) from Streptococcus agalactiae (see 2 papers)
39% identity, 91% coverage of query (135 bits)
TC 3.A.1.132.1 / O30489 GldA, component of The GldAFG putative ABC transporter required for ratchet-type gliding motility; may function in secretion of a macromolecule such as an exopolysaccharide. (Agarwal et al., 1997; Hunnicutt et al., 2002; McBride and Zhu 2013). Soluble GldG homologues (no TMSs) are found in eukaryotes (e.g. intraflagellar protein transporter, IPT52 of Chlamydomonas reinhardtii; XP_001692161) from Cytophaga johnsonae (Flavobacterium johnsoniae) (see paper)
32% identity, 90% coverage of query (134 bits)
TC 3.A.1.105.4 / Q4VWC9 PltI, component of The pyoluteorin (a chlorinated polyketide) efflux pump, PltHIJKN (see 2 papers)
37% identity, 95% coverage of query (134 bits)
YbhF / b0794 ABC exporter ATP binding subunit YbhF (EC 7.6.2.2) from Escherichia coli K-12 substr. MG1655 (see 8 papers)
ybhF / P0A9U1 ABC exporter ATP binding subunit YbhF (EC 7.6.2.2) from Escherichia coli (strain K12) (see 6 papers)
YBHF_ECOLI / P0A9U1 Probable multidrug ABC transporter ATP-binding protein YbhF from Escherichia coli (strain K12) (see paper)
ybhF / MB|P0A9U1 uncharacterized ABC transporter ATP-binding protein ybhF from Escherichia coli K12 (see paper)
33% identity, 93% coverage of query (130 bits)
TC 3.A.1.105.10 / F1QZ58 AbcG homologue, ABCH1 of 705 aas and 6 TMSs in a C-M arrangement from Danio rerio
30% identity, 97% coverage of query (125 bits)
natA / P46903 Na+ ABC efflux transporter ATP-binding protein (EC 7.2.2.4) from Bacillus subtilis (strain 168) (see paper)
NATA_BACSU / P46903 ABC transporter ATP-binding protein NatA; ABC-type Na(+) transporter; EC 7.2.2.4 from Bacillus subtilis (strain 168) (see 2 papers)
P46903 ABC-type Na+ transporter (EC 7.2.2.4) from Bacillus subtilis (see 2 papers)
TC 3.A.1.115.1 / P46903 NatA; ATP-binding transport protein (Na(+) ABC transporter), component of Na+ efflux pump NatAB from Bacillus subtilis (see 3 papers)
natA / GB|BAA22236.1 sodium extrusion ABC transporter, ATP-binding protein NatA from Bacillus subtilis (see paper)
31% identity, 93% coverage of query (122 bits)
TC 3.A.1.102.1 / P50332 NodI, component of Lipooligosaccharide exporter (nodulation proteins, NodIJ) from Rhizobium galegae (see paper)
35% identity, 90% coverage of query (121 bits)
3nhaA Nucleotide binding domain of human abcb6 (adp mg bound structure)
34% identity, 92% coverage of query (121 bits)
nodI / GB|AAB16898.1 nodulation ATP-binding protein I from Rhizobium sp. N33 (see paper)
34% identity, 93% coverage of query (119 bits)
TC 3.A.1.1.38 / Q9WYQ2 Glycerol-3-phosphate-transporting ATPase, component of Inositol phosphate porter (Rodionova et al. 2013). Binds inositol phosphate with low Kd and inositol with a lower affinity from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
33% identity, 91% coverage of query (117 bits)
ABCB6_MESAU / A0A125QXJ1 ATP-binding cassette sub-family B member 6; ABC-type heme transporter ABCB6; Mitochondrial ABC transporter 3; Mt-ABC transporter 3; P-glycoprotein-related protein; Ubiquitously-expressed mammalian ABC half transporter; EC 7.6.2.5 from Mesocricetus auratus (Golden hamster) (see paper)
34% identity, 92% coverage of query (117 bits)
PGA1_c27970 N-Acetyl-D-glucosamine ABC transport system, ATPase component from Phaeobacter inhibens BS107
34% identity, 89% coverage of query (116 bits)
sagG / GI|23305059 ABC transporter, ATP-binding protein SagG from Streptococcus iniae (see paper)
33% identity, 89% coverage of query (116 bits)
ABCB6_HUMAN / Q9NP58 ATP-binding cassette sub-family B member 6; ABC-type heme transporter ABCB6; Mitochondrial ABC transporter 3; Mt-ABC transporter 3; P-glycoprotein-related protein; Ubiquitously-expressed mammalian ABC half transporter; EC 7.6.2.5 from Homo sapiens (Human) (see 23 papers)
TC 3.A.1.210.6 / Q9NP58 Mitochondrial outer membrane/lysosome anionic porphyrin uptake half ABC transporter, ABCB6. Expressed in many mammalian tissues (including fetal liver) in response to intracellular porphyrin. Porphyrin uptake activates de novo porphyrin (haem) biosynthesis from Homo sapiens (Human) (see 7 papers)
ABCB6 / RF|NP_005680.1 ATP-binding cassette sub-family B member 6, mitochondrial from Homo sapiens (see paper)
34% identity, 92% coverage of query (116 bits)
7dnzA / Q9NP58 Cryo-em structure of the human abcb6 (hemin and gsh-bound) (see paper)
34% identity, 92% coverage of query (116 bits)
3nh9A Nucleotide binding domain of human abcb6 (atp bound structure)
34% identity, 92% coverage of query (116 bits)
7dnyB Cryo-em structure of the human abcb6 (coproporphyrin iii-bound)
34% identity, 92% coverage of query (116 bits)
8k7bA Post-occluded structure of human abcb6 w546a mutant (adp/vo4-bound)
34% identity, 92% coverage of query (116 bits)
7dnzB Cryo-em structure of the human abcb6 (hemin and gsh-bound)
34% identity, 92% coverage of query (116 bits)
ABCB6_MOUSE / Q9DC29 ATP-binding cassette sub-family B member 6; ABC-type heme transporter ABCB6; EC 7.6.2.5 from Mus musculus (Mouse) (see 7 papers)
33% identity, 92% coverage of query (115 bits)
YhiG / b3486 ribosome-associated ATPase from Escherichia coli K-12 substr. MG1655 (see 13 papers)
RBBA_ECOLI / P37624 Ribosome-associated ATPase; Ribosomal bound ATPase from Escherichia coli (strain K12) (see 5 papers)
yhiH / RF|YP_026225 uncharacterized ABC transporter ATP-binding protein yhiH from Escherichia coli K12 (see paper)
32% identity, 95% coverage of query (115 bits)
AB25B_ORYSJ / Q9FNU2 ABC transporter B family member 25; ABC transporter ABCB.25; OsABCB25; Protein ALS1 homolog; Protein ALUMINUM SENSITIVE 1; OsALS1 from Oryza sativa subsp. japonica (Rice) (see paper)
34% identity, 90% coverage of query (114 bits)
ABCB6_RAT / O70595 ATP-binding cassette sub-family B member 6; ABC-type heme transporter ABCB6; Ubiquitously-expressed mammalian ABC half transporter; EC 7.6.2.5 from Rattus norvegicus (Rat) (see 3 papers)
34% identity, 92% coverage of query (114 bits)
7eklA Mitochondrial outer membrane protein
34% identity, 92% coverage of query (114 bits)
TC 3.A.1.105.2 / Q53716 OleC4, component of Oleandomycin (drug resistance) exporter from Streptomyces antibioticus (see paper)
33% identity, 88% coverage of query (112 bits)
YehX / b2129 glycine betaine ABC transporter ATP binding subunit YehX from Escherichia coli K-12 substr. MG1655 (see 3 papers)
yehX / P33360 glycine betaine ABC transporter ATP binding subunit YehX from Escherichia coli (strain K12) (see 3 papers)
YEHX_ECOLI / P33360 Glycine betaine uptake system ATP-binding protein YehX; EC 7.4.2.- from Escherichia coli (strain K12) (see 2 papers)
32% identity, 98% coverage of query (112 bits)
TC 3.A.1.105.8 / Q7UE58 ABC-type multidrug transport system, ATPase component, component of ABC-2 transporter from Rhodopirellula baltica (strain SH1)
39% identity, 87% coverage of query (112 bits)
AB27B_ARATH / Q0WML0 ABC transporter B family member 27; ABC transporter ABCB.27; AtABCB27; Aluminum tolerance-related ATP-binding cassette transporter; Antigen peptide transporter-like 2; Transporter associated with antigen processing-like protein 2; AtTAP2 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
TC 3.A.1.201.8 / Q0WML0 The aluminum chelate (aluminum sensitivity (ALS1)) protein; expressed in root vacuoles half-type ABC transporter from Arabidopsis thaliana (Mouse-ear cress) (see 5 papers)
TAP2 / RF|NP_198720.2 antigen peptide transporter-like 2 from Arabidopsis thaliana (see paper)
34% identity, 90% coverage of query (111 bits)
TC 3.A.1.131.1 / P42332 BcrA, component of The 2 or 3 component bacitracin-resistance efflex pump, BcrAB or BcrABC (Podlesek et al., 1995; Bernard et al., 2003) (BcrA is most similar to SpaF (3.A.1.124.2), but BcrB (5-6 TMSs) is only distantly related to other ABC2-type membrane proteins (Wang et al., 2009). BcrC is not sufficiently similar to detect similarity in BLAST searches. BcrC (5TMSs) belongs to the PAP2 phosphatase superfamily and may not be a contituent of the BcrAB transporter. Transcription is regulated by BcrR, a one-component transmembrane signal transduction system from Bacillus licheniformis (see paper)
bcrA / GB|AAA99504.1 bacitracin ABC transporter, ATP-binding protein BcrA from Bacillus licheniformis (see paper)
30% identity, 90% coverage of query (111 bits)
PGP1_CAEEL / P34712 Multidrug resistance protein pgp-1; P-glycoprotein A; P-glycoprotein-related protein 1; EC 7.6.2.2 from Caenorhabditis elegans (see paper)
P34712 ABC-type xenobiotic transporter (EC 7.6.2.2) from Caenorhabditis elegans (see paper)
TC 3.A.1.201.14 / P34712 P-glycoprotein-1 MDR exporter from Caenorhabditis elegans
33% identity, 93% coverage of query (110 bits)
IRTA_MYCT3 / G7CBF5 Mycobactin import ATP-binding/permease protein IrtA; EC 7.2.2.- from Mycolicibacterium thermoresistibile (strain ATCC 19527 / DSM 44167 / CIP 105390 / JCM 6362 / NCTC 10409 / 316) (Mycobacterium thermoresistibile) (see paper)
36% identity, 93% coverage of query (109 bits)
4f4cA / P34712 The crystal structure of the multi-drug transporter (see paper)
33% identity, 88% coverage of query (108 bits)
7zoaB / Q2YQ73 Cryo-em structure of cgt abc transporter in presence of cbg substrate (see paper)
35% identity, 88% coverage of query (107 bits)
1mv5B Crystal structure of lmra atp-binding domain
32% identity, 88% coverage of query (105 bits)
1mv5A / Q9CHL8 Crystal structure of lmra atp-binding domain
32% identity, 88% coverage of query (105 bits)
7znuA Cryo-em structure of cgt abc transporter in detergent micelle
34% identity, 86% coverage of query (105 bits)
ABCAC_MOUSE / E9Q876 Glucosylceramide transporter ABCA12; ATP-binding cassette sub-family A member 12; EC 7.6.2.1 from Mus musculus (Mouse) (see 9 papers)
32% identity, 84% coverage of query (104 bits)
Build an alignment for PfGW456L13_3525 and 40 homologs with ≥ 30% identity
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6qv0B Structure of atp-bound outward-facing tm287/288 in complex with sybody sb_tm35
29% identity, 92% coverage of query (103 bits)
8f5bA / P78363 Human abca4 structure in complex with amp-pnp
30% identity, 83% coverage of query (103 bits)
6quzD / Q9WYC4 Structure of atpgs-bound outward-facing tm287/288 in complex with sybody sb_tm35 (see paper)
29% identity, 92% coverage of query (103 bits)
IRTA_MYCTU / P9WQJ9 Mycobactin import ATP-binding/permease protein IrtA; Iron-regulated transporter A; EC 7.2.2.- from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 4 papers)
TC 3.A.1.21.2 / P63391 IrtA, component of The Fe3+-carboxymycobactin transporter, IrtAB (Rodriguez and Smith, 2006). IrtA contains an FAD-binding domain (see 2 papers)
33% identity, 86% coverage of query (103 bits)
ABCA4_HUMAN / P78363 Retinal-specific phospholipid-transporting ATPase ABCA4; ATP-binding cassette sub-family A member 4; RIM ABC transporter; RIM proteinv; RmP; Retinal-specific ATP-binding cassette transporter; Stargardt disease protein; EC 7.6.2.1 from Homo sapiens (Human) (see 38 papers)
TC 3.A.1.211.2 / P78363 The retinal-specific ABC transporter (RIM protein, ABCR or ABCA4) (Stargardt's disease protein, involved in retinal/macular degeneration) in the rod outer segment. Changes in the oligomeric state of the nucleotide binding domains of ABCR are coupled to ATP hydrolysis and might represent a signal for the TMDs of ABCR to export the bound substrate (Biswas-Fiss 2006). The ABCA4 porter flips N-retinylidene-phosphatidylethanolamine, a product generated from the photobleaching of rhodopsin, from the lumen to the cytoplasmic side of disc membranes following the photobleaching of rhodopsin, insuring that retinoids do not accumulate in disc membranes (Molday, 2007; Molday et al. 2009; Tsybovsky et al. 2013). It also transports several vitamin A derivatives (Sun, 2011) and phosphatidylethanolamine in the same direction. Mutations, known to cause Stargardt disease, decrease N-retinylidene-phosphatidylethanolamine and phosphatidylethanolamine transport activities (Quazi et al. 2012). It functions as an inwardly directed retinoid flippase in the visual cycle from Homo sapiens (Human) (see 28 papers)
30% identity, 83% coverage of query (102 bits)
IRTA_MYCS2 / A0R6H8 Mycobactin import ATP-binding/permease protein IrtA; EC 7.2.2.- from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see paper)
33% identity, 88% coverage of query (102 bits)
7wixA Cryo-em structure of mycobacterium tuberculosis irtab in complex with adp
34% identity, 86% coverage of query (102 bits)
7wivA / P9WQJ9 Cryo-em structure of mycobacterium tuberculosis irtab in complex with an amp-pnp (see paper)
34% identity, 86% coverage of query (102 bits)
7qkrA / F2QQK6 Cryo-em structure of abc transporter ste6-2p from pichia pastoris with verapamil at 3.2 a resolution (see paper)
31% identity, 86% coverage of query (102 bits)
7lkzA Structure of atp-bound human abca4
29% identity, 83% coverage of query (102 bits)
7e7qA / P78363 Cryo-em structure of human abca4 in atp-bound state (see paper)
29% identity, 83% coverage of query (102 bits)
4u00A / Q5SJ55 Crystal structure of ttha1159 in complex with adp (see paper)
29% identity, 90% coverage of query (102 bits)
ABCA3_HUMAN / Q99758 Phospholipid-transporting ATPase ABCA3; ABC-C transporter; ATP-binding cassette sub-family A member 3; ATP-binding cassette transporter 3; ATP-binding cassette 3; Xenobiotic-transporting ATPase ABCA3; EC 7.6.2.1; EC 7.6.2.2 from Homo sapiens (Human) (see 18 papers)
TC 3.A.1.211.5 / Q99758 The surfactant-secreting porter, ABCA3 (exports lipids and proteins into lamellar bodies). Fatal surfactant deficiency (FSD) can result from mutations in ABCA3, causing abnormal intracellular localization (type I) or decreased ATP hydrolysis (type II). Other mutations cause pediatric interstitial lung disease (pILD) from Homo sapiens (Human) (see 7 papers)
ABCA3 / RF|NP_001080.2 ATP-binding cassette sub-family A member 3 from Homo sapiens (see paper)
32% identity, 87% coverage of query (101 bits)
ECFA1_STRT2 / Q5M243 Energy-coupling factor transporter ATP-binding protein EcfA1; ECF transporter A component EcfA1; EC 7.-.-.- from Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311) (see paper)
TC 3.A.1.25.6 / Q5M243 Energy-coupling factor transporter ATP-binding protein EcfA 2, component of Riboflavin ECF transport system, EcfAA'T/RibU from Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311)
32% identity, 86% coverage of query (101 bits)
1g291 / Q9YGA6 Malk (see paper)
28% identity, 91% coverage of query (101 bits)
ABCBA_MOUSE / Q9JI39 ATP-binding cassette sub-family B member 10, mitochondrial; ABC-mitochondrial erythroid protein; ABC-me protein; ATP-binding cassette transporter 10; ABC transporter 10 protein from Mus musculus (Mouse) (see 9 papers)
33% identity, 93% coverage of query (101 bits)
7e7oA / P78363 Cryo-em structure of human abca4 in nrpe-bound state (see paper)
30% identity, 82% coverage of query (101 bits)
7wiwA Cryo-em structure of mycobacterium tuberculosis irtab complexed with atp in an occluded conformation
33% identity, 86% coverage of query (101 bits)
7w02A / Q99758 Cryo-em structure of atp-bound abca3 (see paper)
32% identity, 87% coverage of query (100 bits)
7ph2A Nanodisc reconstituted msba in complex with nanobodies, spin-labeled at position a60c
31% identity, 92% coverage of query (100 bits)
7ph3A / P60752 Amp-pnp bound nanodisc reconstituted msba with nanobodies, spin- labeled at position a60c (see paper)
31% identity, 92% coverage of query (100 bits)
7lkpA Structure of atp-free human abca4
29% identity, 81% coverage of query (100 bits)
MsbA / b0914 ATP-binding lipopolysaccharide transport protein (EC 7.5.2.6) from Escherichia coli K-12 substr. MG1655 (see 54 papers)
msbA / P60752 ATP-binding lipopolysaccharide transport protein (EC 7.5.2.6) from Escherichia coli (strain K12) (see 57 papers)
MSBA_ECOLI / P60752 ATP-dependent lipid A-core flippase; Lipid A export ATP-binding/permease protein MsbA; Lipid flippase; EC 7.5.2.6 from Escherichia coli (strain K12) (see 17 papers)
P60752 ABC-type lipid A-core oligosaccharide transporter (EC 7.5.2.6); P-type phospholipid transporter (EC 7.6.2.1) from Escherichia coli (see 13 papers)
TC 3.A.1.106.1 / P60752 Phospholipid, LPS, lipid A and drug exporter, MsbA, which flips the substrate from the inner leaflet of the cytoplasmic membrane to the outer leaflet (Eckford and Sharom, 2010). MsbA also confers drug resistance to azidopine, daunomycin, vinblastine, Hoechst 33342 and ethidium (Reuter et al., 2003). Four x-ray structures, trapped in different conformations, two with and two without nucleotide, have been solved (Ward et al., 2007). They suggest an alternating accessibility mode of transport with major conformational changes from Escherichia coli (see 11 papers)
msbA / MB|P60752 lipid A export ATP-binding/permease protein msbA; EC 3.6.3.- from Escherichia coli K12 (see 24 papers)
31% identity, 92% coverage of query (100 bits)
7mewA E. Coli msba in complex with g247
31% identity, 92% coverage of query (100 bits)
8dmmA Structure of the vanadate-trapped msba bound to kdl
31% identity, 92% coverage of query (100 bits)
6bppA E. Coli msba in complex with lps and inhibitor g092
31% identity, 92% coverage of query (100 bits)
6bplA E. Coli msba in complex with lps and inhibitor g907
31% identity, 92% coverage of query (100 bits)
7bcwA Structure of msba in salipro with adp vanadate
31% identity, 92% coverage of query (100 bits)
ABCA3_MOUSE / Q8R420 Phospholipid-transporting ATPase ABCA3; ATP-binding cassette sub-family A member 3; Xenobiotic-transporting ATPase ABCA3; EC 7.6.2.1; EC 7.6.2.2 from Mus musculus (Mouse) (see 7 papers)
32% identity, 89% coverage of query (100 bits)
7m1qA / P78363 Human abca4 structure in complex with n-ret-pe (see paper)
29% identity, 84% coverage of query (100 bits)
MALK_SALTY / P19566 Maltose/maltodextrin import ATP-binding protein MalK; EC 7.5.2.1 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
29% identity, 93% coverage of query (99.8 bits)
BMRA_BACSU / O06967 Multidrug resistance ABC transporter ATP-binding/permease protein BmrA; EC 7.6.2.- from Bacillus subtilis (strain 168) (see 7 papers)
TC 3.A.1.117.3 / O06967 Multidrug resistance homodimeric efflux pump, BmrA (YvcC) of 589 aas from Bacillus subtilis (strain 168)
32% identity, 92% coverage of query (99.4 bits)
7pruA Structure of ctatm1 in the inward-facing partially occluded with cargo bound
30% identity, 84% coverage of query (98.6 bits)
P0AAH0 Phosphate import ATP-binding protein PstB; ABC phosphate transporter; Phosphate-transporting ATPase; EC 7.3.2.1 from Escherichia coli (strain K12)
29% identity, 90% coverage of query (98.6 bits)
7pr1A / G0SBE6 Structure of ctatm1 in the occluded conformation with atp bound (see paper)
30% identity, 84% coverage of query (98.2 bits)
ABCA6_HUMAN / Q8N139 ATP-binding cassette sub-family A member 6; EC 7.6.2.- from Homo sapiens (Human) (see 3 papers)
TC 3.A.1.211.15 / Q8N139 ATP-binding cassette sub-family A member 6, ABCA6 of 1617 aas. This transporter may play a role in macrophage lipid homeostasis. It is up-regulated during monocyte differentiation into macrophages but down-regulated by cholesterol loading of macrophages from Homo sapiens
32% identity, 87% coverage of query (98.2 bits)
MalK / b4035 maltose ABC transporter ATP binding subunit (EC 7.5.2.1) from Escherichia coli K-12 substr. MG1655 (see 31 papers)
MalK / P68187 maltose ABC transporter ATP binding subunit (EC 7.5.2.1) from Escherichia coli (strain K12) (see 29 papers)
MALK_ECOLI / P68187 Maltose/maltodextrin import ATP-binding protein MalK; EC 7.5.2.1 from Escherichia coli (strain K12) (see 6 papers)
P68187 ABC-type maltose transporter (subunit 3/3) (EC 7.5.2.1) from Escherichia coli (see paper)
TC 3.A.1.1.1 / P68187 Maltose/maltodextrin import ATP-binding protein MalK aka B4035, component of Maltooligosaccharide porter. The 3-D structure has been reported by Oldham et al. (2007). An altering access mechanism has been suggested for the maltose transporter resulting from rigid-body rotations (Khare et al., 2009). Bordignon et al. (2010) and Schneider et al. (2012) have reviewed the extensive knowledge available on MalEFGK2, its mode of action and its regulatory interactions from Escherichia coli (see 17 papers)
malK / RF|NP_418459 maltose/maltodextrin import ATP-binding protein malK; EC 3.6.3.19 from Escherichia coli K12 (see 18 papers)
30% identity, 93% coverage of query (98.2 bits)
ECSA_BACSU / P55339 ABC-type transporter ATP-binding protein EcsA from Bacillus subtilis (strain 168) (see paper)
TC 3.A.1.143.1 / P55339 ABC-type transporter ATP-binding protein EcsA, component of The exoprotein (including α-amylase) secretion system, EcsAB(C) (Leskelä et al., 1999). Also may play roles in sporulation, competence (Leskelä et al., 1996) and transformation using purified DNA (Takeno et al., 2011). An involvement of EcsC in transport is not established, but it is homologous to the C-terminus of the P-type ATPase, 3.A.3.31.2 from Bacillus subtilis (strain 168) (see 3 papers)
31% identity, 93% coverage of query (97.8 bits)
4ayxA / Q9NRK6 Structure of the human mitochondrial abc transporter, abcb10 (rod form b) (see paper)
32% identity, 90% coverage of query (97.8 bits)
6fn1A Zosuquidar and uic2 fab complex of human-mouse chimeric abcb1 (abcb1hm)
30% identity, 92% coverage of query (97.4 bits)
4mrvA Structure of a bacterial atm1-family abc transporter
34% identity, 88% coverage of query (97.4 bits)
4mrsA Structure of a bacterial atm1-family abc transporter
34% identity, 88% coverage of query (97.4 bits)
4mrpA Structure of a bacterial atm1-family abc transporter
34% identity, 88% coverage of query (97.4 bits)
4mrnA / Q2G506 Structure of a bacterial atm1-family abc transporter (see paper)
34% identity, 88% coverage of query (97.4 bits)
ATM1_NOVAD / Q2G506 ATM1-type heavy metal exporter; ATP-binding cassette transporter Atm1; NaAtm1; EC 7.-.-.- from Novosphingobium aromaticivorans (strain ATCC 700278 / DSM 12444 / CCUG 56034 / CIP 105152 / NBRC 16084 / F199) (see paper)
34% identity, 88% coverage of query (97.4 bits)
6panA Structure of a bacterial atm1-family abc exporter with atp bound
35% identity, 85% coverage of query (97.4 bits)
7zk6A Abcb1 l335c mutant (mabcb1) in the outward facing state bound to 2 molecules of aac
30% identity, 92% coverage of query (97.1 bits)
7zk5A Abcb1 l335c mutant (mabcb1) in the outward facing state bound to aac
30% identity, 92% coverage of query (97.1 bits)
7zk4A The abcb1 l335c mutant (mabcb1) in the outward facing state
30% identity, 92% coverage of query (97.1 bits)
6parA Structure of a bacterial atm1-family abc exporter with mgamppnp bound
34% identity, 88% coverage of query (97.1 bits)
7zkaA Abcb1 v978c mutant (mabcb1) in the outward facing state bound to aac
30% identity, 92% coverage of query (97.1 bits)
2d62A / O57933 Crystal structure of multiple sugar binding transport atp- binding protein
26% identity, 91% coverage of query (97.1 bits)
ECFA2_STRT2 / Q5M244 Energy-coupling factor transporter ATP-binding protein EcfA2; ECF transporter A component EcfA2; EC 3.6.3.- from Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311) (see paper)
TC 3.A.1.25.6 / Q5M244 Energy-coupling factor transporter ATP-binding protein EcfA 1, component of Riboflavin ECF transport system, EcfAA'T/RibU from Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311)
30% identity, 88% coverage of query (97.1 bits)
7bg4A Multidrug resistance transporter bmra mutant e504a bound with atp, mg, and rhodamine 6g solved by cryo-em
31% identity, 92% coverage of query (96.7 bits)
7ow8A / O06967 Cryoem structure of the abc transporter bmra e504a mutant in complex with atp-mg (see paper)
31% identity, 92% coverage of query (96.7 bits)
2onjA Structure of the multidrug abc transporter sav1866 from s. Aureus in complex with amp-pnp
31% identity, 88% coverage of query (96.7 bits)
Y1866_STAAM / Q99T13 Putative multidrug export ATP-binding/permease protein SAV1866; EC 7.6.2.- from Staphylococcus aureus (strain Mu50 / ATCC 700699) (see paper)
Q99T13 ABC-type xenobiotic transporter (EC 7.6.2.2) from Staphylococcus aureus (see paper)
TC 3.A.1.106.2 / Q2G2M9 The homodimeric Sav1866 multidrug exporter (transports doxorubicin, verapamil, ethidium, tetraphenylphosphonium, vinblastine and the fluorescent dye, Hoechst 33342; 3-D structure known at 3 Å resolution; Dawson and Locher, 2006; Velamakanni et al., 2008) The empty site opens by rotation of the nucleotide-binding domain whereas the ATP-bound site remains occluded (Jones and George, 2011). Conformational changes induced by ATP-binding and hydrolysis have been proposed (Becker et al. 2010; Oliveira et al., 2011). The alternating access mechanism and the flippase activity of this ABC exporter has been shown to be lipid-dependent (Becker et al. 2010; Oliveira et al., 2011). The alternating access mechanism and the flippase activity of this ABC exporter has been shown to be lipid-dependent from Staphylococcus aureus (strain NCTC 8325)
2hydA / Q99T13 Multidrug abc transporter sav1866 (see paper)
31% identity, 88% coverage of query (96.7 bits)
ABCB7_ORYLA / H2LNR5 Iron-sulfur clusters transporter ABCB7, mitochondrial; ATP-binding cassette sub-family B member 7, mitochondrial from Oryzias latipes (Japanese rice fish) (Japanese killifish) (see paper)
29% identity, 88% coverage of query (96.7 bits)
ABCAD_MOUSE / Q5SSE9 ATP-binding cassette sub-family A member 13; EC 7.6.2.- from Mus musculus (Mouse) (see 3 papers)
32% identity, 80% coverage of query (96.7 bits)
6pamA Structure of a bacterial atm1-family abc transporter with mgadp bound
34% identity, 88% coverage of query (96.7 bits)
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Lawrence Berkeley National Laboratory