Searching for up to 100 curated homologs for PfGW456L13_4586 FitnessBrowser__pseudo13_GW456_L13:PfGW456L13_4586 (454 a.a.)
Found high-coverage hits (≥70%) to 42 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
RR42_RS32055 3-carboxymuconate cycloisomerase PcaB (EC 5.5.1.2) from Cupriavidus basilensis FW507-4G11
53% identity, 94% coverage of query (415 bits)
pcaB / AAC37149.1 beta-carboxy-cis,cis-muconate cycloisomerase from Acinetobacter baylyi (see 11 papers)
46% identity, 97% coverage of query (402 bits)
YBN5_SCHPO / O42889 Uncharacterized protein C8E4.05c from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
40% identity, 96% coverage of query (333 bits)
TAD1 / A0A0U2UYC4 trans-aconitate decarboxylase (EC 4.1.1.113) from Ustilago maydis (see paper)
TAD1_USTMD / A0A0U2UYC4 Trans-aconitate decarboxylase 1; Itaconic acid/2-hydroxyparaconate biosynthesis cluster protein TAD1; EC 4.1.1.113 from Ustilago maydis (Corn smut fungus) (see 2 papers)
A0A0U2UYC4 trans-aconitate decarboxylase (EC 4.1.1.113) from Ustilago maydis (see paper)
37% identity, 96% coverage of query (309 bits)
pcaB2 / Q2HNY9 3-carboxymuconate lactonizing enzyme type 2 (EC 5.5.1.2) from Hydrogenophaga intermedia (see 2 papers)
40% identity, 91% coverage of query (305 bits)
2SL_DICD3 / E0SKP1 N-acetyl-S-(2-succino)cysteine lyase; S-(2-succino) lyase; 2SL; EC 4.3.2.- from Dickeya dadantii (strain 3937) (Erwinia chrysanthemi (strain 3937)) (see paper)
37% identity, 96% coverage of query (284 bits)
CREDH_STRDJ / K4R6W4 Nitrosuccinate lyase; EC 4.3.99.5 from Streptomyces davaonensis (strain DSM 101723 / JCM 4913 / KCC S-0913 / 768) (see paper)
43% identity, 93% coverage of query (279 bits)
2SL_ENTI1 / E6LDH5 N-acetyl-S-(2-succino)cysteine lyase; S-(2-succino) lyase; 2SL; EC 4.3.2.- from Enterococcus italicus (strain DSM 15952 / CCUG 50447 / LMG 22039 / TP 1.5) (see paper)
36% identity, 96% coverage of query (274 bits)
creD / A0A0K2JL82 nitrosuccinate lyase (EC 4.3.99.5) from Streptomyces cremeus (see paper)
CRED_STRCM / A0A0K2JL82 Nitrosuccinate lyase; EC 4.3.99.5 from Streptomyces cremeus (see 3 papers)
A0A0K2JL82 nitrosuccinate lyase (EC 4.3.99.5) from Streptomyces cremeus (see paper)
42% identity, 94% coverage of query (267 bits)
MJ0929 / Q58339 adenylosuccinate lyase (EC 4.3.2.2) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (see 2 papers)
35% identity, 96% coverage of query (261 bits)
5xnzA / A0A0K2JL82 Crystal structure of cred complex with fumarate (see paper)
41% identity, 94% coverage of query (253 bits)
PUR8_STAAW / Q7A0G9 Adenylosuccinate lyase; ASL; Adenylosuccinase; ASase; EC 4.3.2.2 from Staphylococcus aureus (strain MW2) (see paper)
Q7A0G9 adenylosuccinate lyase (EC 4.3.2.2) from Staphylococcus aureus (see paper)
31% identity, 95% coverage of query (209 bits)
2x75A / Q7A0G9 Staphylococcus aureus adenylosuccinate lyase (see paper)
31% identity, 95% coverage of query (203 bits)
Q2HNZ1 3-Carboxy-cis,cis-muconate cycloisomerase (EC 5.5.1.2) from Agrobacterium tumefaciens (see paper)
36% identity, 78% coverage of query (189 bits)
Build an alignment for PfGW456L13_4586 and 14 homologs with ≥ 30% identity
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PUR8_BACSU / P12047 Adenylosuccinate lyase; ASL; Adenylosuccinase; ASase; Glutamyl--tRNA ligase regulatory factor; EC 4.3.2.2 from Bacillus subtilis (strain 168) (see 2 papers)
P12047 adenylosuccinate lyase (EC 4.3.2.2) from Bacillus subtilis (see paper)
purB / GI|143366 (glutamyl-trna synthetase regulatory factor); EC 4.3.2.2 from Bacillus subtilis (see 4 papers)
29% identity, 95% coverage of query (184 bits)
pcaB / AAF34266.1 3-carboxy-cis,cis-muconate cycloisomerase from Agrobacterium tumefaciens (see 2 papers)
35% identity, 78% coverage of query (181 bits)
toyF / B6CWI9 succinylo-toyocamycin phosphate lyase from Streptomyces rimosus (see paper)
34% identity, 95% coverage of query (179 bits)
PUR8_THEMA / Q9X0I0 Adenylosuccinate lyase; ASL; Adenylosuccinase; ASase; EC 4.3.2.2 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
27% identity, 96% coverage of query (179 bits)
Q8ZY28 adenylosuccinate lyase (EC 4.3.2.2) from Pyrobaculum aerophilum (see paper)
30% identity, 80% coverage of query (134 bits)
4eeiB / Q5NIQ1 Crystal structure of adenylosuccinate lyase from francisella tularensis complexed with amp and succinate
24% identity, 92% coverage of query (102 bits)
5hw2A Crystal structure of adenylosuccinate lyase from francisella tularensis complexed with fumaric acid
24% identity, 92% coverage of query (100 bits)
ADSL / P30566 adenylosuccinate lyase (EC 4.3.2.2) from Homo sapiens (see 3 papers)
PUR8_HUMAN / P30566 Adenylosuccinate lyase; ADSL; ASL; Adenylosuccinase; ASase; EC 4.3.2.2 from Homo sapiens (Human) (see 14 papers)
P30566 adenylosuccinate lyase (EC 4.3.2.2) from Homo sapiens (see 5 papers)
25% identity, 96% coverage of query (84.0 bits)
5nx9D / A0A384E0N4 Crystal structure of neanderthal adenylosuccinate lyase (adsl) in complex with its products amp and fumarate (see paper)
25% identity, 96% coverage of query (82.0 bits)
B2LS18 adenylosuccinate lyase (EC 4.3.2.2) from Ctenopharyngodon idella (see paper)
25% identity, 96% coverage of query (79.0 bits)
ade8 / RF|NP_596735.1 adenylosuccinate lyase Ade8; EC 4.3.2.2 from Schizosaccharomyces pombe (see paper)
23% identity, 96% coverage of query (75.9 bits)
Q5SKT5 fumarate hydratase (EC 4.2.1.2) from Thermus thermophilus (see paper)
26% identity, 70% coverage of query (75.5 bits)
5nxaB Crystal structure of neanderthal adenylosuccinate lyase (adsl)in complex with its products aicar and fumarate
26% identity, 76% coverage of query (75.5 bits)
Q8NRN8 fumarate hydratase (EC 4.2.1.2) from Corynebacterium glutamicum (see 2 papers)
29% identity, 76% coverage of query (72.8 bits)
ARLY_NOSP7 / Q9LAE5 Argininosuccinate lyase; ASAL; ASL; Arginosuccinase; EC 4.3.2.1 from Nostoc punctiforme (strain ATCC 29133 / PCC 73102) (see paper)
Q9LAE5 argininosuccinate lyase (EC 4.3.2.1) from Nostoc sp. (see paper)
25% identity, 70% coverage of query (72.4 bits)
ADE13 enzyme of adenine biosynthesis from Candida albicans (see paper)
24% identity, 77% coverage of query (66.6 bits)
ade13 / Q05911 Ade13 (EC 4.3.2.2) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see paper)
26% identity, 76% coverage of query (65.9 bits)
Q05911 Adenylosuccinate lyase; ASL; Adenylosuccinase; ASase; EC 4.3.2.2 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
26% identity, 76% coverage of query (65.9 bits)
ARLY_MOUSE / Q91YI0 Argininosuccinate lyase; ASAL; Arginosuccinase; EC 4.3.2.1 from Mus musculus (Mouse) (see paper)
26% identity, 78% coverage of query (64.3 bits)
5nxaA Crystal structure of neanderthal adenylosuccinate lyase (adsl)in complex with its products aicar and fumarate
24% identity, 96% coverage of query (63.5 bits)
5nxaC / A0A384E0N4 Crystal structure of neanderthal adenylosuccinate lyase (adsl)in complex with its products aicar and fumarate (see paper)
23% identity, 96% coverage of query (60.5 bits)
2ptqA Crystal structure of escherichia coli adenylosuccinate lyase mutant h171n with bound amp and fumarate
25% identity, 95% coverage of query (59.3 bits)
5nx9C / A0A384E0N4 Crystal structure of neanderthal adenylosuccinate lyase (adsl) in complex with its products amp and fumarate (see paper)
24% identity, 96% coverage of query (58.5 bits)
Ade / b1131 adenylosuccinate lyase (EC 4.3.2.2) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
purB / P0AB89 adenylosuccinate lyase (EC 4.3.2.2) from Escherichia coli (strain K12) (see 8 papers)
PUR8_ECOLI / P0AB89 Adenylosuccinate lyase; ASL; Adenylosuccinase; ASase; EC 4.3.2.2 from Escherichia coli (strain K12) (see 3 papers)
purB / MB|P0AB89 adenylosuccinate lyase from Escherichia coli K12 (see 2 papers)
25% identity, 94% coverage of query (58.2 bits)
2e9fB / Q5SLL0 Crystal structure of t.Th.Hb8 argininosuccinate lyase complexed with l-arginine
27% identity, 71% coverage of query (57.8 bits)
3gzhA / Q8X737 Crystal structure of phosphate-bound adenylosuccinate lyase from e. Coli (see paper)
25% identity, 94% coverage of query (57.4 bits)
5vkwB / A0A1D8PT56 Crystal structure of adenylosuccinate lyase ade13 from candida albicans
23% identity, 77% coverage of query (55.5 bits)
7t29A / Q9I0K9 Crystal structure of adenylosuccinate lyase (asl) from pseudomonas aeruginosa complexed with amp
24% identity, 85% coverage of query (45.4 bits)
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