Searching for up to 100 curated homologs for PfGW456L13_4772 FitnessBrowser__pseudo13_GW456_L13:PfGW456L13_4772 (223 a.a.)
Found high-coverage hits (≥70%) to 38 curated proteins.
Removed hits that are identical to the query, leaving 37
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
Pf1N1B4_773 ABC transporter for L-asparagine and L-glutamate, permease subunit 2 from Pseudomonas fluorescens FW300-N1B4
97% identity, 100% coverage of query (436 bits)
AO353_16280 ABC transporter for L-aspartate, L-asparagine, L-glutamate, and L-glutamine, permease component 1 from Pseudomonas fluorescens FW300-N2E3
88% identity, 100% coverage of query (410 bits)
TC 3.A.1.3.22 / Q9I404 Amino acid ABC transporter membrane protein, component of Amino acid transporter, AatJMQP. Probably transports L-glutamic acid, D-glutamine acid, L-glutamine and N-acetyl L-glutamic acid (Johnson et al. 2008). Very similar to 3.A.1.3.19 of P. putida from Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
82% identity, 99% coverage of query (386 bits)
TC 3.A.1.3.19 / Q88NY4 PP1069, component of Acidic amino acid uptake porter, AatJMQP from Pseudomonas putida (strain KT2440) (see paper)
86% identity, 100% coverage of query (381 bits)
GltK / b0653 glutamate/aspartate ABC transporter membrane subunit GltK (EC 7.4.2.1) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
GltK / P0AER5 glutamate/aspartate ABC transporter membrane subunit GltK (EC 7.4.2.1) from Escherichia coli (strain K12) (see 3 papers)
GLTK_ECOLI / P0AER5 Glutamate/aspartate import permease protein GltK from Escherichia coli (strain K12) (see 2 papers)
TC 3.A.1.3.4 / P0AER5 Glutamate/aspartate transport system permease protein GltK aka B0653, component of Glutamate/aspartate porter from Escherichia coli (see 4 papers)
54% identity, 99% coverage of query (223 bits)
TC 3.A.1.3.25 / Q9CES5 Glutamine ABC transporter permease and substrate binding protein protein, component of Glutamine transporter, GlnQP. Takes up glutamine, asparagine and glutamate which compete for each other for binding both substrate and the transmembrane protein constituent of the system (Fulyani et al. 2015). Tandem substrate binding domains (SBDs) differ in substrate specificity and affinity, allowing cells to efficiently accumulate different amino acids via a single ABC transporter. Analysis revealed the roles of individual residues in determining the substrate affinity from Lactococcus lactis subsp. lactis (strain IL1403)
38% identity, 91% coverage of query (135 bits)
ARTQ_BACSU / P54536 Arginine transport system permease protein ArtQ from Bacillus subtilis (strain 168) (see paper)
34% identity, 99% coverage of query (134 bits)
YhdY / b3270 putative ABC transporter membrane subunit YhdY from Escherichia coli K-12 substr. MG1655 (see 5 papers)
35% identity, 92% coverage of query (131 bits)
Pf6N2E2_5404 ABC transporter for D-Alanine, permease component 1 from Pseudomonas fluorescens FW300-N2E2
34% identity, 92% coverage of query (127 bits)
TC 3.A.1.3.17 / Q8YSA2 Basic amino acid uptake transporter, BgtAB (see paper)
37% identity, 93% coverage of query (124 bits)
TC 3.A.1.3.22 / Q9I403 Amino acid ABC transporter membrane protein, component of Amino acid transporter, AatJMQP. Probably transports L-glutamic acid, D-glutamine acid, L-glutamine and N-acetyl L-glutamic acid (Johnson et al. 2008). Very similar to 3.A.1.3.19 of P. putida from Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
32% identity, 92% coverage of query (119 bits)
TC 3.A.1.3.19 / Q88NY3 PP1070, component of Acidic amino acid uptake porter, AatJMQP from Pseudomonas putida (strain KT2440) (see paper)
33% identity, 85% coverage of query (119 bits)
PfGW456L13_4771 ABC transporter for L-Asparagine and possibly other L-amino acids, permease component 1 from Pseudomonas fluorescens GW456-L13
34% identity, 85% coverage of query (119 bits)
Pf1N1B4_772 ABC transporter for L-asparagine and L-glutamate, permease component 1 from Pseudomonas fluorescens FW300-N1B4
33% identity, 85% coverage of query (117 bits)
GLNP_BACSU / O34606 Probable glutamine ABC transporter permease protein GlnP from Bacillus subtilis (strain 168) (see paper)
36% identity, 92% coverage of query (117 bits)
AO353_16285 ABC transporter for L-aspartate, L-asparagine, L-glutamate, and L-glutamine, permease component 2 from Pseudomonas fluorescens FW300-N2E3
32% identity, 85% coverage of query (115 bits)
4ymtC / Q8RCC3 Crystal structure of an amino acid abc transporter complex with arginines (see paper)
30% identity, 99% coverage of query (115 bits)
GlnP / b0810 L-glutamine ABC transporter membrane subunit (EC 7.4.2.1) from Escherichia coli K-12 substr. MG1655 (see 2 papers)
GlnP / P0AEQ6 L-glutamine ABC transporter membrane subunit (EC 7.4.2.1) from Escherichia coli (strain K12) (see 2 papers)
TC 3.A.1.3.2 / P0AEQ6 Glutamine transport system permease protein GlnP aka B0810, component of Three component ABC L-glutamine porter. The basal ATPase activity (ATP hydrolysis in the absence of substrate) is mainly caused by the docking of the closed-unliganded state of GlnH onto the transporter domain of GlnPQ. Unlike glutamine, arginine binds both GlnH domains, but does not trigger their closing. Comparison of the ATPase activity in nanodiscs with glutamine transport in proteoliposomes suggested that the stoichiometry of ATP per substrate is close to two from Escherichia coli (see 5 papers)
32% identity, 100% coverage of query (115 bits)
4ymwC Crystal structure of an amino acid abc transporter with histidines
30% identity, 99% coverage of query (115 bits)
TC 3.A.1.3.18 / Q8YPM7 NatH, component of Acidic and neutral amino acid uptake transporter NatFGH/BgtA. BgtA is shared with BgtAB (see paper)
34% identity, 96% coverage of query (112 bits)
Ac3H11_2554 ABC transporter for L-Histidine, permease component 1 from Acidovorax sp. GW101-3H11
31% identity, 99% coverage of query (109 bits)
TC 3.A.1.3.12 / P73544 BgtB aka GLNH aka SLL1270, component of Arginine/lysine/histidine/glutamine porter (see paper)
35% identity, 92% coverage of query (109 bits)
SMc02120 ABC transporter for L-Glutamine, L-Histidine, and other L-amino acids, permease component 2 from Sinorhizobium meliloti 1021
33% identity, 92% coverage of query (107 bits)
TC 3.A.1.3.8 / Q52814 AapM, component of General L-amino acid porter; transports basic and acidic amino acids preferentially, but also transports aliphatic amino acids (catalyzes both uptake and efflux) from Rhizobium leguminosarum (biovar viciae) (see 2 papers)
aapM / CAA57935.1 general amino acid ABC type transporter from Rhizobium leguminosarum (see paper)
32% identity, 92% coverage of query (103 bits)
GLNM_BACSU / O34671 Probable glutamine ABC transporter permease protein GlnM from Bacillus subtilis (strain 168) (see paper)
32% identity, 91% coverage of query (101 bits)
GLUD_CORGL / P48245 Glutamate transport system permease protein GluD; Glutamate uptake system protein GluD from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see paper)
TC 3.A.1.3.9 / P48245 GluD aka CGL1953, component of Glutamate porter from Corynebacterium glutamicum (Brevibacterium flavum) (see 2 papers)
31% identity, 94% coverage of query (100 bits)
GltJ / b0654 glutamate/aspartate ABC transporter membrane subunit GltJ (EC 7.4.2.1) from Escherichia coli K-12 substr. MG1655 (see 2 papers)
GltJ / P0AER3 glutamate/aspartate ABC transporter membrane subunit GltJ (EC 7.4.2.1) from Escherichia coli (strain K12) (see 2 papers)
GLTJ_ECOLI / P0AER3 Glutamate/aspartate import permease protein GltJ from Escherichia coli (strain K12) (see 2 papers)
TC 3.A.1.3.4 / P0AER3 Glutamate/aspartate transport system permease protein GltJ aka B0654, component of Glutamate/aspartate porter from Escherichia coli (see 4 papers)
30% identity, 87% coverage of query (99.8 bits)
Build an alignment for PfGW456L13_4772 and 27 homologs with ≥ 30% identity
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AO356_00470 ABC transporter for D-Glucosamine, permease component 1 from Pseudomonas fluorescens FW300-N2C3
Pf6N2E2_2051 ABC transporter for D-Glucosamine Hydrochloride, permease component 1 from Pseudomonas fluorescens FW300-N2E2
29% identity, 94% coverage of query (99.4 bits)
TC 3.A.1.3.18 / Q8YPM8 NatG, component of Acidic and neutral amino acid uptake transporter NatFGH/BgtA. BgtA is shared with BgtAB (see paper)
32% identity, 81% coverage of query (99.0 bits)
TC 3.A.1.3.21 / Q9I487 Amino acid ABC transporter membrane protein, component of Hydroxy L-proline uptake porter, HprABC from Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
36% identity, 92% coverage of query (98.6 bits)
TC 3.A.1.3.23 / Q9HU29 Amino acid (Lysine/arginine/ornithine/histidine/octopine) ABC transporter membrane protein, component of Amino acid transporter, PA5152-PA5155. Probably transports numerous amino acids including lysine, arginine, histidine, D-alanine and D-valine (Johnson et al. 2008). Regulated by ArgR from Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
30% identity, 97% coverage of query (98.6 bits)
TC 3.A.1.3.7 / Q52665 BztC, component of Glutamate/glutamine/aspartate/asparagine porter from Rhodobacter capsulatus (Rhodopseudomonas capsulata) (see paper)
30% identity, 91% coverage of query (98.2 bits)
TC 3.A.1.3.16 / A1VZQ3 PEP1B, component of Uptake system for glutamate and aspartate from Campylobacter jejuni subsp. jejuni serotype O:23/36 (strain 81-176)
28% identity, 91% coverage of query (96.7 bits)
AO353_21720 ABC transporter for D-glucosamine, permease component 2 from Pseudomonas fluorescens FW300-N2E3
28% identity, 94% coverage of query (96.3 bits)
TC 3.A.1.3.6 / P35113 NocM aka ATU6025 aka AGR_PTI_65, component of Nopaline porter from Agrobacterium tumefaciens (see 3 papers)
32% identity, 95% coverage of query (95.9 bits)
TC 3.A.1.3.11 / O50183 AotP aka AotM aka PA0890, component of Arginine/ornithine (but not lysine) porter from Pseudomonas aeruginosa (see 2 papers)
34% identity, 99% coverage of query (95.1 bits)
AO356_09910 ABC transporter for L-Lysine, permease component 2 from Pseudomonas fluorescens FW300-N2C3
32% identity, 97% coverage of query (94.4 bits)
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Lawrence Berkeley National Laboratory