Searching for up to 100 curated homologs for PfGW456L13_4782 FitnessBrowser__pseudo13_GW456_L13:PfGW456L13_4782 (441 a.a.)
Found high-coverage hits (≥70%) to 54 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
YcjJ / b1296 putrescine:H+ symporter PuuP from Escherichia coli K-12 substr. MG1655 (see 4 papers)
puuP / P76037 putrescine:H+ symporter PuuP from Escherichia coli (strain K12) (see 2 papers)
PUUP_ECOLI / P76037 Putrescine importer PuuP from Escherichia coli (strain K12) (see 4 papers)
TC 2.A.3.1.13 / P76037 Putrescine importer, PuuP from Escherichia coli (strain K12) (see 4 papers)
45% identity, 98% coverage of query (367 bits)
puuP / BAD88704.1 putrescine importer, partial from Escherichia coli K-12 (see paper)
45% identity, 98% coverage of query (366 bits)
YeeF / b2014 putrescine:H+ symporter PlaP from Escherichia coli K-12 substr. MG1655 (see paper)
plaP / P0AA47 putrescine:H+ symporter PlaP from Escherichia coli (strain K12) (see 5 papers)
PLAP_ECOLI / P0AA47 Low-affinity putrescine importer PlaP; Putrescine low affinity permease from Escherichia coli (strain K12) (see 2 papers)
TC 2.A.3.1.14 / P0AA47 Low-affinity putrescine importer PlaP from Escherichia coli (strain K12) (see 5 papers)
42% identity, 98% coverage of query (338 bits)
Build an alignment for PfGW456L13_4782 and 3 homologs with ≥ 30% identity
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MTRTR_BACSU / Q797A7 Methylthioribose transporter from Bacillus subtilis (strain 168) (see paper)
27% identity, 96% coverage of query (120 bits)
BCAP_BACSU / O07576 Branched-chain amino acid permease BcaP; BCAA permease from Bacillus subtilis (strain 168) (see 4 papers)
26% identity, 82% coverage of query (115 bits)
6f34A / Q5L1G5 Crystal structure of a bacterial cationic amino acid transporter (cat) homologue bound to arginine. (see paper)
29% identity, 76% coverage of query (103 bits)
5oqtA Crystal structure of a bacterial cationic amino acid transporter (cat) homologue
29% identity, 76% coverage of query (102 bits)
BCAP_LACLM / A2RHI9 Branched-chain amino acid permease BcaP; BCAA permease; BCAA transporter from Lactococcus lactis subsp. cremoris (strain MG1363) (see 2 papers)
26% identity, 89% coverage of query (97.1 bits)
TC 2.A.3.3.23 / S6EX81 Branched chain amino acid (Leucine/isoleucine/valine) uptake transporter of 469 aas and 12 TMSs, BcaP or CitA from Lactococcus lactis subsp. lactis A12
26% identity, 90% coverage of query (96.3 bits)
CAAT9_ARATH / Q9C5D6 Cationic amino acid transporter 9, chloroplastic from Arabidopsis thaliana (Mouse-ear cress) (see paper)
27% identity, 82% coverage of query (94.4 bits)
CAAT2_ARATH / Q9ASS7 Cationic amino acid transporter 2, vacuolar from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
TC 2.A.3.3.13 / Q9ASS7 Cationic amino acid transporter 2, vacuolar from Arabidopsis thaliana (see 4 papers)
26% identity, 85% coverage of query (93.6 bits)
N515DRAFT_2924 L-proline transporter from Dyella japonica UNC79MFTsu3.2
24% identity, 81% coverage of query (93.2 bits)
CAAT4_ARATH / Q8W4K3 Cationic amino acid transporter 4, vacuolar from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
TC 2.A.3.3.14 / Q8W4K3 Cationic amino acid transporter 4, vacuolar from Arabidopsis thaliana (see 4 papers)
26% identity, 79% coverage of query (93.2 bits)
CTR1_HUMAN / P30825 High affinity cationic amino acid transporter 1; CAT-1; CAT1; Ecotropic retroviral leukemia receptor homolog; Ecotropic retrovirus receptor homolog; Solute carrier family 7 member 1; System Y+ basic amino acid transporter from Homo sapiens (Human) (see 4 papers)
TC 2.A.3.3.9 / P30825 High affinity cationic amino acid transporter 1 (CAT-1) (CAT1) (Ecotropic retroviral leukemia receptor homologue) (Ecotropic retrovirus receptor homologue) (ERR) (Solute carrier family 7 member 1) (System Y+ basic amino acid transporter) from Homo sapiens (see 6 papers)
27% identity, 83% coverage of query (90.5 bits)
CTR1_MOUSE / Q09143 High affinity cationic amino acid transporter 1; CAT-1; CAT1; Ecotropic retroviral leukemia receptor; Ecotropic retrovirus receptor; ERR; EcoR; Solute carrier family 7 member 1; System Y+ basic amino acid transporter from Mus musculus (Mouse) (see 7 papers)
TC 2.A.3.3.1 / Q09143 System Y+ high affinity basic amino acid transporter (CAT1) (ecotropic retrovival leukemia virus receptor (ERR)) (transports arginine, lysine and ornithine; Na+-independent) from Mus musculus (Mouse) (see 2 papers)
Slc7a1 / RF|NP_031539.3 high affinity cationic amino acid transporter 1 from Mus musculus
27% identity, 83% coverage of query (87.8 bits)
CCNA_00435 L-proline transporter from Caulobacter crescentus NA1000
25% identity, 97% coverage of query (87.4 bits)
CTR1_RAT / P30823 High affinity cationic amino acid transporter 1; CAT-1; CAT1; Ecotropic retroviral leukemia receptor; Ecotropic retrovirus receptor; EcoR; Solute carrier family 7 member 1; System Y+ basic amino acid transporter from Rattus norvegicus (Rat) (see paper)
26% identity, 83% coverage of query (86.3 bits)
CAAT3_ARATH / Q8GYB4 Cationic amino acid transporter 3, mitochondrial from Arabidopsis thaliana (Mouse-ear cress) (see paper)
27% identity, 76% coverage of query (86.3 bits)
Q16N01 ABC-type polar-amino-acid transporter (EC 7.4.2.1) from Aedes aegypti (see paper)
27% identity, 83% coverage of query (85.5 bits)
CAAT6_ARATH / Q9LZ20 Cationic amino acid transporter 6, chloroplastic from Arabidopsis thaliana (Mouse-ear cress) (see paper)
TC 2.A.3.3.4 / Q9LZ20 The amino acid transporter, CAT6. Mediates electrogenic transport of large neutral and cationic amino acids in preference to other amino acids. Present in lateral root primordia, flowers and seeds from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
T1E3_130 / GI|13430548 amino acid transport-like protein from Arabidopsis thaliana (see paper)
25% identity, 87% coverage of query (85.1 bits)
AO353_12275 histidine permease from Pseudomonas fluorescens FW300-N2E3
26% identity, 75% coverage of query (84.0 bits)
ROCE_BACSU / P39137 Amino-acid permease RocE from Bacillus subtilis (strain 168) (see paper)
TC 2.A.3.1.11 / P39137 L-Arginine permease, RocE from Bacillus subtilis (see 3 papers)
26% identity, 99% coverage of query (82.0 bits)
Ga0059261_1577 L-glutamine and L-histidine transporter from Sphingomonas koreensis DSMZ 15582
26% identity, 95% coverage of query (79.0 bits)
YI26_SCHPO / Q9P768 Uncharacterized amino-acid permease P7G5.06 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
per1 plasma membrane amino acid permease Per1 from Schizosaccharomyces pombe (see 2 papers)
25% identity, 71% coverage of query (78.2 bits)
AO356_18530 L-tyrosine transporter from Pseudomonas fluorescens FW300-N2C3
26% identity, 72% coverage of query (77.8 bits)
PfGW456L13_4291 L-tryptophan transporter from Pseudomonas fluorescens GW456-L13
27% identity, 72% coverage of query (77.0 bits)
YLAT1_HUMAN / Q9UM01 Y+L amino acid transporter 1; Monocyte amino acid permease 2; MOP-2; Solute carrier family 7 member 7; y(+)L-type amino acid transporter 1; Y+LAT1; y+LAT-1 from Homo sapiens (Human) (see 18 papers)
TC 2.A.3.8.22 / Q9UM01 Y+L amino acid transporter 1 (Monocyte amino acid permease 2) (MOP-2) (Solute carrier family 7 member 7) (y(+)L-type amino acid transporter 1) (Y+LAT1) (y+LAT-1) from Homo sapiens (see 20 papers)
25% identity, 76% coverage of query (75.9 bits)
AroR / b0112 aromatic amino acid:H+ symporter AroP from Escherichia coli K-12 substr. MG1655 (see 5 papers)
aroP / P15993 aromatic amino acid:H+ symporter AroP from Escherichia coli (strain K12) (see 6 papers)
AROP_ECOLI / P15993 Aromatic amino acid transport protein AroP; Aromatic amino acid:H(+) symporter AroP; General aromatic amino acid permease; General aromatic transport system from Escherichia coli (strain K12) (see 8 papers)
TC 2.A.3.1.3 / P15993 Aromatic amino acid:H+ symporter, AroP of 457 aas and 12 TMSs (Cosgriff and Pittard 1997). Transports phenylalanine, tyrosine and tryptophan from Escherichia coli (see 6 papers)
24% identity, 72% coverage of query (75.9 bits)
CAAT1_ARATH / Q84MA5 Cationic amino acid transporter 1; Amino acid transporter 1 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
22% identity, 87% coverage of query (75.5 bits)
CTR2_HUMAN / P52569 Cationic amino acid transporter 2; CAT-2; CAT2; Low affinity cationic amino acid transporter 2; Solute carrier family 7 member 2 from Homo sapiens (Human) (see 3 papers)
TC 2.A.3.3.8 / P52569 Low affinity cationic amino acid transporter 2 (CAT-2) (CAT2) (Solute carrier family 7 member 2) from Homo sapiens (see 6 papers)
24% identity, 85% coverage of query (75.5 bits)
TC 2.A.3.3.24 / ALD51314.1 Plastidic cationic amino acid transporter, CAT, of 582 aas and 14 TMSs from Petunia x hybrida
25% identity, 78% coverage of query (74.7 bits)
CTR2_MOUSE / P18581 Cationic amino acid transporter 2; CAT-2; CAT2; 20.5; Low affinity cationic amino acid transporter 2; Solute carrier family 7 member 2; T-cell early activation protein; TEA from Mus musculus (Mouse) (see 6 papers)
23% identity, 86% coverage of query (73.9 bits)
YLAT1_RAT / Q9R0S5 Y+L amino acid transporter 1; Solute carrier family 7 member 7; y(+)L-type amino acid transporter 1; Y+LAT1; y+LAT-1 from Rattus norvegicus (Rat) (see 2 papers)
TC 2.A.3.8.7 / Q9R0S5 y+LAT1 (transports neutral amino acids (i.e., Leu) in symport with Na+, Li+ or H+ in 1:1 stoichiometry; transports basic amino acids (i.e., Lys) by facilitated diffusion without a symported cation). Also transports the neurotoxicant, methylmercury-L-cysteine by molecular mimicry. Causes the Lysinuric protein intolerance condition in humans (Q9UM01) (Broer, 2008) (see 2 papers)
25% identity, 76% coverage of query (73.9 bits)
CTR2_CHICK / B3TP03 Cationic amino acid transporter 2; CAT-2; CAT2; cCAT-2; Low affinity cationic amino acid transporter 2; Solute carrier family 7 member 2 from Gallus gallus (Chicken) (see paper)
24% identity, 82% coverage of query (73.6 bits)
TC 2.A.3.3.2 / P18581 Low affinity basic amino acid transporter (CAT2) (T-cell early activation protein (TEA)) (transports arginine, lysine and ornithine; Na+-independent) from Mus musculus (Mouse) (see 9 papers)
Slc7a2 / RF|NP_031540.2 low affinity cationic amino acid transporter 2 from Mus musculus (see paper)
23% identity, 86% coverage of query (72.4 bits)
YLAT1_MOUSE / Q9Z1K8 Y+L amino acid transporter 1; Solute carrier family 7 member 7; y(+)L-type amino acid transporter 1; Y+LAT1; y+LAT-1 from Mus musculus (Mouse) (see 3 papers)
25% identity, 76% coverage of query (72.0 bits)
7p9uB / Q9UPY5 Cryo em structure of system xc- in complex with glutamate (see paper)
23% identity, 82% coverage of query (60.8 bits)
7epzB Overall structure of erastin-bound xct-4f2hc complex
23% identity, 82% coverage of query (60.8 bits)
SLC7A11 / Q9UPY5 cystine/glutamate transporter from Homo sapiens (see paper)
XCT_HUMAN / Q9UPY5 Cystine/glutamate transporter; Amino acid transport system xc-; Calcium channel blocker resistance protein CCBR1; Solute carrier family 7 member 11; xCT from Homo sapiens (Human) (see 9 papers)
TC 2.A.3.8.18 / Q9UPY5 Cystine/glutamate antiporter (Amino acid transport system xCT) (Calcium channel blocker resistance protein CCBR1) (Solute carrier family 7 member 11) from Homo sapiens (see 7 papers)
23% identity, 82% coverage of query (60.5 bits)
7cmiB The lat2-4f2hc complex in complex with leucine
24% identity, 81% coverage of query (57.4 bits)
7cmhB / Q9UHI5 The lat2-4f2hc complex in complex with tryptophan (see paper)
24% identity, 81% coverage of query (57.4 bits)
7b00A Human lat2-4f2hc complex in the apo-state
24% identity, 81% coverage of query (57.4 bits)
SLC7A8 / Q9UHI5 large neutral amino acids transporter small subunit 2 from Homo sapiens (see 4 papers)
LAT2_HUMAN / Q9UHI5 Large neutral amino acids transporter small subunit 2; L-type amino acid transporter 2; hLAT2; Solute carrier family 7 member 8 from Homo sapiens (Human) (see 14 papers)
TC 2.A.3.8.20 / Q9UHI5 Large neutral amino acids transporter small subunit 2 (L-type amino acid transporter 2) (hLAT2) (Solute carrier family 7 member 8). Certain detergents stabilize and allow purification of the 4F2hc-LAT2 complex, allowing the measurement of substrate binding. In addition, an improved 3D map could be obtained from Homo sapiens (see 12 papers)
23% identity, 80% coverage of query (57.0 bits)
6f2wA / A8UCQ5 Bacterial asc transporter crystal structure in open to in conformation (see paper)
22% identity, 89% coverage of query (56.2 bits)
GABP_BACSU / P46349 Gamma-aminobutyric acid permease; GABA permease; 4-aminobutyrate permease; Gamma-aminobutyrate permease; Proline transporter GabP from Bacillus subtilis (strain 168) (see 3 papers)
TC 2.A.3.1.5 / P46349 β-alanine/γ-aminobutyrate/proline/3,4-dehydroproline:H+ symporter, GabP from Bacillus subtilis (see 4 papers)
gabP / AAC44641.1 gamma-aminobutyrate permease from Bacillus subtilis (see 2 papers)
21% identity, 92% coverage of query (55.8 bits)
7dsqB Overall structure of the lat1-4f2hc bound with 3,5-diiodo-l-tyrosine
25% identity, 84% coverage of query (55.1 bits)
7dsnB Overall structure of the lat1-4f2hc bound with jx-119
25% identity, 84% coverage of query (55.1 bits)
7dslB Overall structure of the lat1-4f2hc bound with jx-078
25% identity, 84% coverage of query (55.1 bits)
7dskB / Q01650 Overall structure of the lat1-4f2hc bound with jx-075 (see paper)
25% identity, 84% coverage of query (55.1 bits)
SLC7A5 / Q01650 large neutral amino acids transporter small subunit 1 from Homo sapiens (see 4 papers)
LAT1_HUMAN / Q01650 Large neutral amino acids transporter small subunit 1; 4F2 light chain; 4F2 LC; 4F2LC; CD98 light chain; Integral membrane protein E16; E16; L-type amino acid transporter 1; hLAT1; Solute carrier family 7 member 5; y+ system cationic amino acid transporter from Homo sapiens (Human) (see 19 papers)
TC 2.A.3.8.25 / Q01650 Large neutral amino acids transporter small subunit 1 (4F2 light chain) (4F2 LC) (4F2LC) (CD98 light chain; SLC3A2) (Integral membrane protein E16) (L-type amino acid transporter 1) (hLAT1) (Solute carrier family 7 member 5) (y+ system cationic and neutral amino acid transporter) from Homo sapiens (see 24 papers)
25% identity, 84% coverage of query (54.7 bits)
LAT2_MOUSE / Q9QXW9 Large neutral amino acids transporter small subunit 2; L-type amino acid transporter 2; mLAT2; Solute carrier family 7 member 8 from Mus musculus (Mouse) (see 6 papers)
23% identity, 76% coverage of query (53.5 bits)
6irtB Human lat1-4f2hc complex bound with bch
24% identity, 83% coverage of query (52.4 bits)
BAT1_HUMAN / P82251 b(0,+)-type amino acid transporter 1; b(0,+)AT1; Glycoprotein-associated amino acid transporter b0,+AT1; Solute carrier family 7 member 9 from Homo sapiens (Human) (see 16 papers)
TC 2.A.3.8.19 / P82251 B(0,+)-type amino acid transporter 1 (B(0,+)AT) (Glycoprotein-associated amino acid transporter b0,+AT1) (Solute carrier family 7 member 9) from Homo sapiens (see 9 papers)
23% identity, 73% coverage of query (50.8 bits)
6li9B / P82251 Heteromeric amino acid transporter b0,+at-rbat complex bound with arginine (see paper)
23% identity, 73% coverage of query (50.4 bits)
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Lawrence Berkeley National Laboratory