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Searching for up to 100 curated homologs for PfGW456L13_841 FitnessBrowser__pseudo13_GW456_L13:PfGW456L13_841 (235 a.a.)

Found high-coverage hits (≥70%) to 17 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

Q88B12 2-haloacid dehalogenase (configuration-inverting) (EC 3.8.1.10) from Pseudomonas syringae (see paper)
3vayA / Q88B12 Crystal structure of 2-haloacid dehalogenase from pseudomonas syringae pv. Tomato dc3000 (see paper)
    74% identity, 97% coverage of query (356 bits)

YigB / b3812 5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase (EC 3.1.3.104; EC 3.1.3.102) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
yigB / P0ADP0 5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase (EC 3.1.3.104; EC 3.1.3.102) from Escherichia coli (strain K12) (see 4 papers)
YIGB_ECOLI / P0ADP0 5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase YigB; EC 3.1.3.104 from Escherichia coli (strain K12) (see 3 papers)
yigB / RF|NP_418257 uncharacterized protein yigB from Escherichia coli K12 (see 2 papers)
    34% identity, 96% coverage of query (124 bits)

PSP_THET2 / Q72H00 Phosphoserine phosphatase; PSP; EC 3.1.3.3 from Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27) (see paper)
    35% identity, 88% coverage of query (98.2 bits)

Build an alignment

Build an alignment for PfGW456L13_841 and 3 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

PSP_BACSU / P94512 Phosphoserine phosphatase; PSP; EC 3.1.3.3 from Bacillus subtilis (strain 168) (see paper)
    26% identity, 97% coverage of query (75.5 bits)

3i76B / O06480 The crystal structure of the orthorhombic form of the putative had- hydrolase yfnb from bacillus subtilis bound to magnesium reveals interdomain movement
    30% identity, 94% coverage of query (75.1 bits)

6q7oA Crystal structure of oe1
    27% identity, 88% coverage of query (75.1 bits)

6q7nA Crystal structure of bh32 alkylated with the mechanistic inhibitor 2- bromoacetophenone
    27% identity, 88% coverage of query (75.1 bits)

8bp1A Crystal structure of bhmehis1.0, an engineered enzyme for the morita- baylis-hillman reaction (see paper)
    28% identity, 83% coverage of query (73.2 bits)

3qnmA / Q8A5G8 Haloalkane dehalogenase family member from bacteroides thetaiotaomicron of unknown function
    28% identity, 94% coverage of query (64.7 bits)

Halxa_2271 / F8D9F4 RuBP 5-phosphatase (EC 3.1.3.109) from Halopiger xanaduensis (strain DSM 18323 / JCM 14033 / SH-6) (see paper)
RUBPP_HALXS / F8D9F4 Ribulose-1,5-bisphosphate 5-phosphatase; RuBP phosphatase; EC 3.1.3.109 from Halopiger xanaduensis (strain DSM 18323 / JCM 14033 / SH-6) (see paper)
    26% identity, 95% coverage of query (61.2 bits)

G3PP_METJA / Q58832 Glyceraldehyde 3-phosphate phosphatase; EC 3.1.3.- from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see paper)
    26% identity, 94% coverage of query (60.1 bits)

PYNA_STRR6 / Q8DPQ3 Pyrimidine 5'-nucleotidase PynA; Antimutator protein PynA; House-cleaning nucleotidase; Non-canonical pyrimidine nucleotide phosphatase; Nucleoside 5'-monophosphate phosphohydrolase; Pyrimidine nucleotidase A; Ribonucleotide monophosphatase; EC 3.1.3.5 from Streptococcus pneumoniae (strain ATCC BAA-255 / R6) (see paper)
    27% identity, 97% coverage of query (59.3 bits)

HAD_AGRTR / P60527 (S)-2-haloacid dehalogenase; 2-haloalkanoic acid dehalogenase; Cryptic L-isomer-specific dehalogenase; DhlS5I; Halocarboxylic acid halidohydrolase; L-2-haloacid dehalogenase; L-DEX; EC 3.8.1.2 from Agrobacterium tumefaciens (strain RS5) (see paper)
    26% identity, 96% coverage of query (53.1 bits)

Nanp / Q5M969 N-acetylneuraminate-9-phosphate phosphatase (EC 3.1.3.29) from Rattus norvegicus (see 2 papers)
NANP_RAT / Q5M969 N-acylneuraminate-9-phosphatase; Haloacid dehalogenase-like hydrolase domain-containing protein 4; Neu5Ac-9-Pase; EC 3.1.3.29 from Rattus norvegicus (Rat) (see paper)
    24% identity, 96% coverage of query (49.7 bits)

4g9bA / P77366 Crystal structure of beta-phosphoglucomutase homolog from escherichia coli, target efi-501172, with bound mg, open lid
    26% identity, 100% coverage of query (47.0 bits)

ycjU / P77366 β-phosphoglucomutase (EC 5.4.2.6) from Escherichia coli (strain K12) (see 4 papers)
PGMB_ECOLI / P77366 Beta-phosphoglucomutase; Beta-PGM; EC 5.4.2.6 from Escherichia coli (strain K12) (see 4 papers)
P77366 beta-Phosphoglucomutase (EC 5.4.2.6) from Escherichia coli (see paper)
    26% identity, 99% coverage of query (46.6 bits)

YhfE / b3385 phosphoglycolate phosphatase (EC 3.1.3.18) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
gph / P32662 phosphoglycolate phosphatase (EC 3.1.3.18) from Escherichia coli (strain K12) (see 7 papers)
GPH_ECOLI / P32662 Phosphoglycolate phosphatase; PGP; PGPase; EC 3.1.3.18 from Escherichia coli (strain K12) (see 3 papers)
    27% identity, 95% coverage of query (45.1 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory