Searching for up to 100 curated homologs for RR42_RS00385 FitnessBrowser__Cup4G11:RR42_RS00385 (280 a.a.)
Found high-coverage hits (≥70%) to 46 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
BMULJ_04921 / A0A0H3KT28 2,4-didehydro-3-deoxy-L-fuconate hydrolase (EC 3.7.1.26) from Burkholderia multivorans (strain ATCC 17616 / 249) (see 2 papers)
64% identity, 99% coverage of query (363 bits)
BPHYT_RS34210 2,4-diketo-3-deoxy-L-rhamnonate hydrolase (EC 3.7.1.-) from Burkholderia phytofirmans PsJN
64% identity, 99% coverage of query (358 bits)
HSERO_RS06355 2,4-diketo-3-deoxy-L-fuconate hydrolase (EC 3.7.1.26) from Herbaspirillum seropedicae SmR1
62% identity, 99% coverage of query (358 bits)
C785_RS20550 / A0A2E7P912 5-hydroxy-2,4-dioxopentanoate hydrolase (EC 3.7.1.26) from Herbaspirillum sp. (see paper)
62% identity, 99% coverage of query (356 bits)
SM_b21112 L-2,4-diketo-3-deoxyrhamnonate hydrolase; 2,4-dioxopentanoate hydrolase from Sinorhizobium meliloti 1021
62% identity, 100% coverage of query (353 bits)
UGL_BURL3 / Q39BA7 Ureidoglycolate lyase; UGL; Ureidoglycolase; Ureidoglycolatase; Ureidoglycolate hydrolase; EC 4.3.2.3 from Burkholderia lata (strain ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 / R18194 / 383) (see paper)
65% identity, 98% coverage of query (350 bits)
lra6 / Q1NEI7 2,4-didehydro-3-deoxy-L-fuconate hydrolase (EC 3.7.1.26) from Sphingomonas sp. (strain SKA58) (see paper)
61% identity, 100% coverage of query (329 bits)
8gsrA / Q1NEI7 Crystal structure of l-2,4-diketo-3-deoxyrhamnonate hydrolase from sphingomonas sp. (Apo-form) (see paper)
61% identity, 99% coverage of query (325 bits)
8gstC Crystal structure of l-2,4-diketo-3-deoxyrhamnonate hydrolase from sphingomonas sp. (Pyruvate bound-form)
61% identity, 99% coverage of query (325 bits)
6v77B / A0QTY3 Crystal structure of a putative hpce protein from mycobacterium smegmatis
40% identity, 94% coverage of query (181 bits)
Y2993_MYCTU / I6Y276 Protein Rv2993c from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
45% identity, 74% coverage of query (176 bits)
6iymA / K0A9N9 Fumarylacetoacetate hydrolase (eafah) from psychrophilic exiguobacterium antarcticum (see paper)
37% identity, 99% coverage of query (165 bits)
K0A9N9 fumarylacetoacetase (EC 3.7.1.2) from Exiguobacterium antarcticum (see paper)
37% identity, 99% coverage of query (165 bits)
YISK_BACSU / O06724 Uncharacterized protein YisK from Bacillus subtilis (strain 168) (see paper)
43% identity, 71% coverage of query (164 bits)
8skyB / A0A0D6X359 Crystal structure of yisk from bacillus subtilis in complex with oxalate (see paper)
43% identity, 71% coverage of query (164 bits)
8sutA Crystal structure of yisk from bacillus subtilis in complex with reaction product 4-hydroxy-2-oxoglutaric acid
43% identity, 71% coverage of query (164 bits)
dntG / Q8VUC7 2,4-dihydroxy-5-methyl-6-oxohexa-2,4-dienoate isomerase from Burkholderia cepacia (see 2 papers)
40% identity, 81% coverage of query (162 bits)
3qdfA / B2HIH3 Crystal structure of 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase from mycobacterium marinum (see paper)
43% identity, 74% coverage of query (158 bits)
3r6oA / B1MJ53 Crystal structure of a probable 2-hydroxyhepta-2,4-diene-1, 7- dioateisomerase from mycobacterium abscessus (see paper)
38% identity, 75% coverage of query (153 bits)
FAHD1_MOUSE / Q8R0F8 Acylpyruvase FAHD1, mitochondrial; Fumarylacetoacetate hydrolase domain-containing protein 1; Oxaloacetate decarboxylase; OAA decarboxylase; EC 3.7.1.5; EC 4.1.1.112 from Mus musculus (Mouse) (see 2 papers)
40% identity, 73% coverage of query (152 bits)
6sbiA / Q8R0F8 X-ray structure of murine fumarylacetoacetate hydrolase domain containing protein 1 (fahd1) in complex with inhibitor oxalate (see paper)
40% identity, 73% coverage of query (152 bits)
A0A1R4GQY2 3-fumarylpyruvate hydrolase (EC 3.7.1.20) from Corynebacterium glutamicum (see paper)
41% identity, 71% coverage of query (152 bits)
6j5xA / Q8NLC0 Crystal structure of fumarylpyruvate hydrolase from corynebacterium glutamicum in complex with mn2+ and pyruvate (see paper)
41% identity, 71% coverage of query (152 bits)
FAHD1_ARATH / Q93ZE5 Probable acylpyruvase FAHD1, mitochondrial; Fumarylacetoacetate hydrolase domain-containing protein 1; FAH domain-containing protein 1; EC 3.7.1.5 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
44% identity, 72% coverage of query (152 bits)
6j5xB Crystal structure of fumarylpyruvate hydrolase from corynebacterium glutamicum in complex with mn2+ and pyruvate
41% identity, 71% coverage of query (152 bits)
FAHD1_HUMAN / Q6P587 Acylpyruvase FAHD1, mitochondrial; Fumarylacetoacetate hydrolase domain-containing protein 1; FAH domain-containing protein 1; Oxaloacetate decarboxylase; OAA decarboxylase; YisK-like protein; EC 3.7.1.5; EC 4.1.1.112 from Homo sapiens (Human) (see 3 papers)
Q6P587 acylpyruvate hydrolase (EC 3.7.1.5); oxaloacetate decarboxylase (EC 4.1.1.112) from Homo sapiens (see 3 papers)
39% identity, 73% coverage of query (150 bits)
6fogA / Q6P587 X-ray structure of homo sapiens fumarylacetoacetate hydrolase domain containing protein 1 (fahd1) in complex with inhibitor oxalate at 1.94a resolution. (see paper)
39% identity, 73% coverage of query (150 bits)
FAHD2_ARATH / Q9LUR3 Probable acylpyruvase FAHD2, mitochondrial; Fumarylacetoacetate hydrolase domain-containing protein 2; FAH domain-containing protein 2; EC 3.7.1.5 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
44% identity, 72% coverage of query (147 bits)
A0A076VF18 fumarylacetoacetase (EC 3.7.1.2) from Rhodotorula diobovata (see paper)
42% identity, 73% coverage of query (145 bits)
YcgM / b1180 putative isomerase/hydrolase from Escherichia coli K-12 substr. MG1655 (see 2 papers)
36% identity, 71% coverage of query (135 bits)
4dbhA / Q8NQY2 Crystal structure of cg1458 with inhibitor (see paper)
37% identity, 74% coverage of query (132 bits)
G2IPX5 maleylpyruvate hydrolase (EC 3.7.1.23) from Sphingobium sp. SYK-6 (see paper)
39% identity, 81% coverage of query (128 bits)
6jvwB / G2IPX5 Crystal structure of maleylpyruvate hydrolase from sphingobium sp. Syk-6 in complex with manganese (ii) ion and pyruvate (see paper)
38% identity, 81% coverage of query (125 bits)
1nr9B / P76004 Crystal structure of escherichia coli 1262 (apc5008), putative isomerase
34% identity, 71% coverage of query (121 bits)
1nr9D / P76004 Crystal structure of escherichia coli 1262 (apc5008), putative isomerase
34% identity, 71% coverage of query (121 bits)
1nr9C / P76004 Crystal structure of escherichia coli 1262 (apc5008), putative isomerase
34% identity, 71% coverage of query (120 bits)
1nr9A / P76004 Crystal structure of escherichia coli 1262 (apc5008), putative isomerase
34% identity, 71% coverage of query (120 bits)
6j5yA / Q9I111 Crystal structure of fumarylpyruvate hydrolase from pseudomonas aeruginosa in complex with mn2+ and pyruvate (see paper)
35% identity, 75% coverage of query (115 bits)
A0A080VH08 3-fumarylpyruvate hydrolase (EC 3.7.1.20) from Pseudomonas aeruginosa (see paper)
35% identity, 75% coverage of query (115 bits)
CPH_NEONM / A0A3G9JYJ6 Caffeoylpyruvate hydrolase; CPH; Fungal bioluminescence cycle protein cph; EC 3.7.-.- from Neonothopanus nambi (Agaricus nambi) (see 2 papers)
30% identity, 98% coverage of query (112 bits)
A0A0M3SVN7 fumarylacetoacetase (EC 3.7.1.2) from Cupriavidus gilardii (see paper)
35% identity, 74% coverage of query (106 bits)
naaD / F8QQ75 3-fumarylpyruvate hydrolase (EC 3.7.1.20) from Bradyrhizobium sp. JS329 (see paper)
35% identity, 74% coverage of query (100 bits)
A0A1B0ZSC0 fumarylacetoacetase (EC 3.7.1.2) from Phaeobacter gallaeciensis (see paper)
35% identity, 79% coverage of query (97.1 bits)
Build an alignment for RR42_RS00385 and 43 homologs with ≥ 30% identity
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A0A0D5YDA5 fumarylacetoacetase (EC 3.7.1.2) from Acinetobacter baumannii (see paper)
29% identity, 71% coverage of query (91.7 bits)
xacE / D4GP28 2-dehydro-3-deoxy-L-arabinonate dehydratase (EC 4.2.1.43; EC 4.2.1.141) from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (see 3 papers)
KDXD_HALVD / D4GP28 Probable 2-keto-3-deoxyxylonate dehydratase; KDXD; EC 4.2.1.141 from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see 2 papers)
29% identity, 74% coverage of query (65.5 bits)
SO1670 fumarylacetoacetate hydrolase (EC 3.7.1.2) from Shewanella oneidensis MR-1
25% identity, 70% coverage of query (50.8 bits)
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Lawrence Berkeley National Laboratory