Searching for up to 100 curated homologs for RR42_RS02235 FitnessBrowser__Cup4G11:RR42_RS02235 (311 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
slcC / Q1QWN6 S-sulfolactate dehydrogenase subunit (EC 1.1.1.310) from Chromohalobacter salexigens (strain ATCC BAA-138 / DSM 3043 / CIP 106854 / NCIMB 13768 / 1H11) (see paper)
SLCC_CHRSD / Q1QWN6 (S)-sulfolactate dehydrogenase; (2S)-3-sulfolactate dehydrogenase; (S)-sulfolactate oxidoreductase; EC 1.1.1.310 from Chromohalobacter salexigens (strain ATCC BAA-138 / DSM 3043 / CIP 106854 / NCIMB 13768 / 1H11) (see paper)
56% identity, 100% coverage of query (303 bits)
HPR_THEMA / Q9X1C1 Hydroxypyruvate reductase; HPR; EC 1.1.1.81 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
41% identity, 89% coverage of query (208 bits)
SERA2_ARATH / O04130 D-3-phosphoglycerate dehydrogenase 2, chloroplastic; PGDH; EC 1.1.1.95 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
O04130 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Arabidopsis thaliana (see 3 papers)
42% identity, 93% coverage of query (205 bits)
A0A1Z4EAX3 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Beta vulgaris (see paper)
42% identity, 88% coverage of query (199 bits)
A0A2R6X868 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Marchantia polymorpha (see paper)
42% identity, 88% coverage of query (197 bits)
1wwkA / O50095 Crystal structure of phosphoglycerate dehydrogenase from pyrococcus horikoshii ot3
42% identity, 97% coverage of query (195 bits)
H9JRZ9 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Bombyx mori (see paper)
42% identity, 87% coverage of query (194 bits)
SERA1_ARATH / O49485 D-3-phosphoglycerate dehydrogenase 1, chloroplastic; Protein EMBRYO SAC DEVELOPMENT ARREST 9; EC 1.1.1.95 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
O49485 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Arabidopsis thaliana (see 4 papers)
42% identity, 85% coverage of query (191 bits)
A0A1Z4EAX4 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Beta vulgaris (see paper)
42% identity, 88% coverage of query (189 bits)
P9WNX3 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Mycobacterium tuberculosis (see 5 papers)
41% identity, 98% coverage of query (186 bits)
3dc2A / P9WNX3 Crystal structure of serine bound d-3-phosphoglycerate dehydrogenase from mycobacterium tuberculosis (see paper)
41% identity, 98% coverage of query (186 bits)
3ddnB Crystal structure of hydroxypyruvic acid phosphate bound d-3- phosphoglycerate dehydrogenase in mycobacterium tuberculosis
41% identity, 98% coverage of query (186 bits)
SERA3_ARATH / Q9LT69 D-3-phosphoglycerate dehydrogenase 3, chloroplastic; EC 1.1.1.95 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q9LT69 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Arabidopsis thaliana (see 4 papers)
41% identity, 88% coverage of query (185 bits)
hprA / P73821 glycerate dehydrogenase (EC 1.1.1.29) from Synechocystis sp. (strain PCC 6803 / Kazusa) (see paper)
34% identity, 99% coverage of query (181 bits)
7dkmA / O43175 Phgdh covalently linked to oridonin (see paper)
37% identity, 91% coverage of query (179 bits)
6cwaA Crystal structure phgdh in complex with nadh and 3-phosphoglycerate at 1.77 a resolution
37% identity, 91% coverage of query (179 bits)
6plgA Crystal structure of human phgdh complexed with compound 15
37% identity, 91% coverage of query (179 bits)
6plfA Crystal structure of human phgdh complexed with compound 1
37% identity, 91% coverage of query (179 bits)
7ewhA Crystal structure of human phgdh in complex with homoharringtonine
37% identity, 91% coverage of query (179 bits)
6rj2A Crystal structure of phgdh in complex with compound 40
37% identity, 91% coverage of query (179 bits)
6rihA Crystal structure of phgdh in complex with compound 9
37% identity, 91% coverage of query (179 bits)
6rj3A Crystal structure of phgdh in complex with compound 15
37% identity, 91% coverage of query (179 bits)
6rj5A Crystal structure of phgdh in complex with compound 39
37% identity, 91% coverage of query (179 bits)
PHGDH / O43175 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) from Homo sapiens (see 3 papers)
SERA_HUMAN / O43175 D-3-phosphoglycerate dehydrogenase; 3-PGDH; 2-oxoglutarate reductase; Malate dehydrogenase; EC 1.1.1.95; EC 1.1.1.399; EC 1.1.1.37 from Homo sapiens (Human) (see 7 papers)
O43175 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Homo sapiens (see 8 papers)
37% identity, 91% coverage of query (177 bits)
SERA_MOUSE / Q61753 D-3-phosphoglycerate dehydrogenase; 3-PGDH; A10; EC 1.1.1.95 from Mus musculus (Mouse) (see paper)
Q61753 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Mus musculus (see 2 papers)
37% identity, 91% coverage of query (177 bits)
Phgdh / O08651 3-phosphoglycerate dehydrogenase subunit (EC 1.1.1.95) from Rattus norvegicus (see paper)
SERA_RAT / O08651 D-3-phosphoglycerate dehydrogenase; 3-PGDH; EC 1.1.1.95 from Rattus norvegicus (Rat) (see paper)
O08651 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Rattus norvegicus (see paper)
37% identity, 91% coverage of query (177 bits)
Q9Z564 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Streptomyces coelicolor (see paper)
39% identity, 98% coverage of query (175 bits)
serA / GB|AAC83943.1 phosphoglycerate dehydrogenase; EC 1.1.1.95 from Bacillus subtilis (see paper)
serA / AAC83943.1 phosphoglycerate dehydrogenase from Bacillus subtilis (see 3 papers)
38% identity, 85% coverage of query (175 bits)
6plfB Crystal structure of human phgdh complexed with compound 1
37% identity, 91% coverage of query (173 bits)
Q8U3Y2 glyoxylate reductase (NADP+) (EC 1.1.1.79); hydroxypyruvate reductase (EC 1.1.1.81) from Pyrococcus furiosus (see paper)
37% identity, 89% coverage of query (171 bits)
5aovA / Q8U3Y2 Ternary crystal structure of pyrococcus furiosus glyoxylate hydroxypyruvate reductase in presence of glyoxylate (see paper)
37% identity, 89% coverage of query (171 bits)
GYAR_THELN / Q9C4M5 Glyoxylate reductase; EC 1.1.1.26 from Thermococcus litoralis (strain ATCC 51850 / DSM 5473 / JCM 8560 / NS-C) (see paper)
Q9C4M5 glyoxylate reductase (EC 1.1.1.26) from Thermococcus litoralis (see paper)
34% identity, 96% coverage of query (167 bits)
F8AEA4 glyoxylate reductase (NADP+) (EC 1.1.1.79); hydroxypyruvate reductase (EC 1.1.1.81) from Pyrococcus yayanosii (see paper)
39% identity, 87% coverage of query (166 bits)
6biiA / F8AEA4 Crystal structure of pyrococcus yayanosii glyoxylate hydroxypyruvate reductase in complex with NADP and malonate (re-refinement of 5aow) (see paper)
39% identity, 87% coverage of query (166 bits)
Q9I6H5 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Pseudomonas aeruginosa (see paper)
38% identity, 86% coverage of query (165 bits)
A4VGK3 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Pseudomonas stutzeri (see paper)
38% identity, 86% coverage of query (164 bits)
Echvi_2777 fused D-3-phosphoglycerate dehydrogenase / phosphoserine phosphatase (EC 1.1.1.95; EC 3.1.3.3) from Echinicola vietnamensis KMM 6221, DSM 17526
36% identity, 81% coverage of query (159 bits)
P87228 Putative D-3-phosphoglycerate dehydrogenase; 3-PGDH; 2-oxoglutarate reductase; EC 1.1.1.95; EC 1.1.1.399 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
35% identity, 87% coverage of query (159 bits)
hprA / Q59516 hydroxypyruvate reductase subunit (EC 1.1.1.81) from Methylorubrum extorquens (strain ATCC 14718 / DSM 1338 / JCM 2805 / NCIMB 9133 / AM1) (see 2 papers)
35% identity, 91% coverage of query (155 bits)
8atiA / P56545 Human ctbp2(31-364) in complex with rai2 peptide(315-322)
40% identity, 80% coverage of query (151 bits)
CTBP2_XENLA / Q9W758 C-terminal-binding protein 2; CtBP2; C-terminal-binding protein B; TCF-3 corepressor CtBP; XCtBP from Xenopus laevis (African clawed frog) (see paper)
39% identity, 80% coverage of query (151 bits)
4lcjA Ctbp2 in complex with substrate mtob
40% identity, 80% coverage of query (151 bits)
2p9eA / P0A9T0 Crystal structure of g336v mutant of e.Coli phosphoglycerate dehydrogenase (see paper)
40% identity, 81% coverage of query (150 bits)
6cdfA / Q13363 Human ctbp1 (28-378) (see paper)
39% identity, 80% coverage of query (150 bits)
6v89A Human ctbp1 (28-375) in complex with amp
39% identity, 80% coverage of query (150 bits)
4u6sA Ctbp1 in complex with substrate phenylpyruvate
39% identity, 80% coverage of query (150 bits)
4u6qA Ctbp1 bound to inhibitor 2-(hydroxyimino)-3-phenylpropanoic acid
39% identity, 80% coverage of query (150 bits)
4lceA Ctbp1 in complex with substrate mtob
39% identity, 80% coverage of query (150 bits)
CTBP2_RAT / Q9EQH5 C-terminal-binding protein 2; CtBP2 from Rattus norvegicus (Rat) (see paper)
40% identity, 80% coverage of query (149 bits)
CTBP2_MOUSE / P56546 C-terminal-binding protein 2; CtBP2 from Mus musculus (Mouse) (see 4 papers)
40% identity, 80% coverage of query (149 bits)
CTBP2_HUMAN / P56545 C-terminal-binding protein 2; CtBP2 from Homo sapiens (Human) (see 5 papers)
40% identity, 80% coverage of query (149 bits)
1hl3A Ctbp/bars in ternary complex with NAD(h) and pidlskk peptide
39% identity, 80% coverage of query (149 bits)
1hkuA Ctbp/bars: a dual-function protein involved in transcription corepression and golgi membrane fission
39% identity, 80% coverage of query (149 bits)
2dbqA / O58320 Crystal structure of glyoxylate reductase (ph0597) from pyrococcus horikoshii ot3, complexed with NADP (i41) (see paper)
37% identity, 91% coverage of query (148 bits)
O58320 Glyoxylate reductase; EC 1.1.1.26 from Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
37% identity, 91% coverage of query (148 bits)
CTBP1 / Q13363 C-terminal-binding protein 1 (EC 1.1.1.428) from Homo sapiens (see 22 papers)
CTBP1_HUMAN / Q13363 C-terminal-binding protein 1; CtBP1; EC 1.1.1.- from Homo sapiens (Human) (see 24 papers)
40% identity, 80% coverage of query (147 bits)
SerA / b2913 phosphoglycerate dehydrogenase (EC 1.1.1.95; EC 1.1.1.399) from Escherichia coli K-12 substr. MG1655 (see 36 papers)
serA / P0A9T0 phosphoglycerate dehydrogenase (EC 1.1.1.95; EC 1.1.1.399) from Escherichia coli (strain K12) (see 36 papers)
SERA_ECOLI / P0A9T0 D-3-phosphoglycerate dehydrogenase; PGDH; 2-oxoglutarate reductase; EC 1.1.1.95; EC 1.1.1.399 from Escherichia coli (strain K12) (see paper)
C3SVM7 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Escherichia coli (see paper)
P0A9T0 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Escherichia coli (see 7 papers)
serA / RF|NP_417388 D-3-phosphoglycerate dehydrogenase; EC 1.1.1.95 from Escherichia coli K12 (see 5 papers)
39% identity, 81% coverage of query (147 bits)
CTBP2_BOVIN / Q0VCQ1 C-terminal-binding protein 2; CtBP2 from Bos taurus (Bovine) (see paper)
40% identity, 80% coverage of query (147 bits)
1psdA The allosteric ligand site in the vmax-type cooperative enzyme phosphoglycerate dehydrogenase
39% identity, 81% coverage of query (147 bits)
1ybaA The active form of phosphoglycerate dehydrogenase
39% identity, 81% coverage of query (147 bits)
YOAD_BACSU / O34815 Putative 2-hydroxyacid dehydrogenase YoaD; EC 1.1.1.- from Bacillus subtilis (strain 168) (see paper)
33% identity, 91% coverage of query (146 bits)
CTBP1_RAT / Q9Z2F5 C-terminal-binding protein 1; CtBP1; 50 kDa BFA-dependent ADP-ribosylation substrate; BARS-50; C-terminal-binding protein 3; CtBP3; EC 1.1.1.- from Rattus norvegicus (Rat) (see 6 papers)
39% identity, 80% coverage of query (146 bits)
CTBP1_MOUSE / O88712 C-terminal-binding protein 1; CtBP1; EC 1.1.1.- from Mus musculus (Mouse) (see 11 papers)
39% identity, 80% coverage of query (146 bits)
O58256 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Pyrococcus horikoshii (see paper)
33% identity, 89% coverage of query (145 bits)
SER33_YEAST / P40510 D-3-phosphoglycerate dehydrogenase 2; 3-PGDH 2; 2-oxoglutarate reductase; EC 1.1.1.95; EC 1.1.1.399 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
31% identity, 97% coverage of query (144 bits)
SERA_YEAST / P40054 D-3-phosphoglycerate dehydrogenase 1; 3-PGDH 1; 2-oxoglutarate reductase; EC 1.1.1.95; EC 1.1.1.399 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
33% identity, 88% coverage of query (143 bits)
HPR_BLAHS / C0CMQ8 Hydroxypyruvate reductase; EC 1.1.1.81 from Blautia hydrogenotrophica (strain DSM 10507 / JCM 14656 / S5a33) (Ruminococcus hydrogenotrophicus) (see paper)
32% identity, 80% coverage of query (143 bits)
U3RH61 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Acanthamoeba castellanii (see paper)
35% identity, 83% coverage of query (141 bits)
2eklA / Q972A9 Structure of st1218 protein from sulfolobus tokodaii
32% identity, 88% coverage of query (140 bits)
Q972A9 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Sulfurisphaera tokodaii (see paper)
32% identity, 88% coverage of query (140 bits)
CTBP_DROME / O46036 C-terminal-binding protein; CtBP protein; dCtBP from Drosophila melanogaster (Fruit fly) (see 2 papers)
39% identity, 80% coverage of query (140 bits)
Q608T2 hydroxypyruvate reductase (EC 1.1.1.81) from Methylococcus capsulatus (see paper)
35% identity, 87% coverage of query (137 bits)
morA / Q2U0N3 D-2-hydroxyacid dehydrogenase (NADP+) (EC 1.1.1.272) from Aspergillus oryzae (strain ATCC 42149 / RIB 40) (see paper)
MORA_ASPOR / Q2U0N3 4-methyl-2-oxopentanoate reductase A; MOA reductase A; MorA; 2-hydroxyacid dehydrogenase D; 2-HadhD; EC 1.1.1.272 from Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold) (see paper)
37% identity, 81% coverage of query (137 bits)
6ttbA / A0A0H3JSR9 Crystal structure of NAD-dependent formate dehydrogenase from staphylococcus aureus in complex with NAD
34% identity, 80% coverage of query (136 bits)
1dxyA / P17584 Structure of d-2-hydroxyisocaproate dehydrogenase (see paper)
32% identity, 72% coverage of query (133 bits)
O66939 D-lactate dehydrogenase (EC 1.1.1.28) from Aquifex aeolicus (see paper)
3kb6B / O66939 Crystal structure of d-lactate dehydrogenase from aquifex aeolicus complexed with NAD and lactic acid (see paper)
33% identity, 79% coverage of query (132 bits)
BPHYT_RS11290 2-ketogluconate 6-phosphate reductase (EC 1.1.1.43) from Burkholderia phytofirmans PsJN
36% identity, 83% coverage of query (132 bits)
GOR1 / P53839 glyoxylate reductase 1 (EC 1.1.1.26) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see paper)
GOR1_YEAST / P53839 Glyoxylate reductase 1; EC 1.1.1.26; EC 1.1.1.79; EC 1.1.1.81 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 4 papers)
33% identity, 95% coverage of query (131 bits)
5dt9A / Q9KQ92 Crystal structure of a putative d-erythronate-4-phosphate dehydrogenase from vibrio cholerae
35% identity, 86% coverage of query (130 bits)
1sc6D / P0A9T0 Crystal structure of w139g d-3-phosphoglycerate dehydrogenase complexed with NAD+ (see paper)
39% identity, 75% coverage of query (127 bits)
HPPR / Q65CJ7 hydroxyphenylpyruvate reductase (EC 1.1.1.237) from Plectranthus scutellarioides (see paper)
HPPR_PLESU / Q65CJ7 Hydroxyphenylpyruvate reductase; HPPR; EC 1.1.1.237 from Plectranthus scutellarioides (Coleus) (Solenostemon scutellarioides) (see paper)
Q65CJ7 hydroxyphenylpyruvate reductase (EC 1.1.1.237) from Plectranthus scutellarioides (see 2 papers)
hppr / CAD47810.2 hydroxyphenylpyruvate reductase (HPPR) from Plectranthus scutellarioides (see paper)
32% identity, 86% coverage of query (122 bits)
3bazA / Q65CJ7 Structure of hydroxyphenylpyruvate reductase from coleus blumei in complex with NADP+ (see paper)
32% identity, 86% coverage of query (122 bits)
2yq5C / Q1GAA2 Crystal structure of d-isomer specific 2-hydroxyacid dehydrogenase from lactobacillus delbrueckii ssp. Bulgaricus: NAD complexed form (see paper)
34% identity, 78% coverage of query (120 bits)
5z20F / Q9I530 The ternary structure of d-lactate dehydrogenase from pseudomonas aeruginosa with nadh and oxamate (see paper)
37% identity, 74% coverage of query (117 bits)
CTBP1_CAEEL / Q20595 C-terminal-binding protein 1 from Caenorhabditis elegans (see 4 papers)
32% identity, 77% coverage of query (117 bits)
4e5kA Thermostable phosphite dehydrogenase in complex with NAD and sulfite
33% identity, 89% coverage of query (117 bits)
7arzA / A9SQZ2 Ternary complex of NAD-dependent formate dehydrogenase from physcomitrium patens
32% identity, 80% coverage of query (115 bits)
4e5mA Thermostable phosphite dehydrogenase e175a/a176r in complex with NADP
33% identity, 89% coverage of query (114 bits)
4e5pA / O69054 Thermostable phosphite dehydrogenase a176r variant in complex with nad (see paper)
33% identity, 89% coverage of query (113 bits)
Build an alignment for RR42_RS02235 and 89 homologs with ≥ 30% identity
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3n7uA NAD-dependent formate dehydrogenase from higher-plant arabidopsis thaliana in complex with NAD and azide
29% identity, 76% coverage of query (112 bits)
3jtmA / Q9S7E4 Structure of recombinant formate dehydrogenase from arabidopsis thaliana
29% identity, 76% coverage of query (112 bits)
FDH1 / Q9S7E4 formate dehydrogenase (EC 1.17.1.9) from Arabidopsis thaliana (see 2 papers)
FDH_ARATH / Q9S7E4 Formate dehydrogenase, chloroplastic/mitochondrial; FDH; NAD-dependent formate dehydrogenase; EC 1.17.1.9 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
Q9S7E4 formate dehydrogenase (EC 1.17.1.9) from Arabidopsis thaliana (see paper)
29% identity, 76% coverage of query (112 bits)
P30901 D-lactate dehydrogenase (EC 1.1.1.28) from Lactobacillus helveticus (see paper)
2dldA / P30901 D-lactate dehydrogenase complexed with nadh and oxamate
GB|CAA47255.1 D-lactate dehydrogenase; EC 1.1.1.28 from Lactobacillus helveticus (see 2 papers)
32% identity, 76% coverage of query (111 bits)
P30901 D-lactate dehydrogenase; D-LDH; D-specific 2-hydroxyacid dehydrogenase; EC 1.1.1.28 from Lactobacillus helveticus (Lactobacillus suntoryeus)
32% identity, 76% coverage of query (111 bits)
4njmA / Q76KF5 Crystal structure of phosphoglycerate bound 3-phosphoglycerate dehydrogenase in entamoeba histolytica (see paper)
27% identity, 70% coverage of query (110 bits)
4njoA Crystal structure of cofactor(NAD+) bound 3-phosphoglycerate dehydrogenase in entamoeba histolytica
27% identity, 70% coverage of query (110 bits)
LDHD_LACDA / P26297 D-lactate dehydrogenase; D-LDH; D-specific 2-hydroxyacid dehydrogenase; EC 1.1.1.28 from Lactobacillus delbrueckii subsp. bulgaricus (strain ATCC 11842 / DSM 20081 / BCRC 10696 / JCM 1002 / NBRC 13953 / NCIMB 11778 / NCTC 12712 / WDCM 00102 / Lb 14) (see paper)
ldhA / OMNI|NTL01LD0096 D-lactate dehydrogenase; EC 1.1.1.28 from Lactobacillus delbrueckii subsp. bulgaricus ATCC 11842 (see 3 papers)
33% identity, 76% coverage of query (109 bits)
5j23A Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with 2'-phospho-adp-ribose
34% identity, 81% coverage of query (109 bits)
5v7nA Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADP and 2-keto-d-gluconic acid
34% identity, 81% coverage of query (109 bits)
5v6qB / Q92LZ4 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADP and malonate (see paper)
34% identity, 81% coverage of query (109 bits)
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