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Searching for up to 100 curated homologs for RR42_RS04840 FitnessBrowser__Cup4G11:RR42_RS04840 (452 a.a.)

Found high-coverage hits (≥70%) to 28 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

gudD / P42206 D-glucarate dehydratase subunit (EC 4.2.1.40) from Pseudomonas putida (see paper)
GUDD_PSEPU / P42206 Glucarate dehydratase; GDH; GlucD; EC 4.2.1.40 from Pseudomonas putida (Arthrobacter siderocapsulatus) (see paper)
    78% identity, 100% coverage of query (722 bits)

YgcX / b2787 D-glucarate dehydratase (EC 4.2.1.40) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
gudD / P0AES2 D-glucarate dehydratase (EC 4.2.1.40) from Escherichia coli (strain K12) (see 5 papers)
GUDD_ECOLI / P0AES2 Glucarate dehydratase; GDH; GlucD; D-glucarate dehydratase; EC 4.2.1.40 from Escherichia coli (strain K12) (see 3 papers)
gudD / RF|NP_417267 glucarate dehydratase; EC 4.2.1.40 from Escherichia coli K12 (see 8 papers)
    73% identity, 97% coverage of query (694 bits)

1ec9D / P0AES2 E. Coli glucarate dehydratase bound to xylarohydroxamate (see paper)
    73% identity, 97% coverage of query (694 bits)

1ec8A E. Coli glucarate dehydratase bound to product 2,3-dihydroxy-5-oxo- hexanedioate
    73% identity, 97% coverage of query (694 bits)

1ecqA E. Coli glucarate dehydratase bound to 4-deoxyglucarate
    73% identity, 97% coverage of query (694 bits)

1jctA Glucarate dehydratase, n341l mutant orthorhombic form
    73% identity, 97% coverage of query (690 bits)

gudD / Q6FFQ2 D-glucarate dehydratase subunit (EC 4.2.1.40) from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
GUDD_ACIAD / Q6FFQ2 Glucarate dehydratase; GDH; GlucD; EC 4.2.1.40 from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
Q6FFQ2 glucarate dehydratase (EC 4.2.1.40) from Acinetobacter baylyi (see paper)
    65% identity, 98% coverage of query (637 bits)

3nxlC / Q39KL8 Crystal structure of glucarate dehydratase from burkholderia cepacia complexed with magnesium
    67% identity, 97% coverage of query (569 bits)

3p0wB / B2UIZ1 Crystal structure of d-glucarate dehydratase from ralstonia solanacearum complexed with mg and d-glucarate
    66% identity, 97% coverage of query (565 bits)

GudX / b2788 glucarate dehydratase-related protein from Escherichia coli K-12 substr. MG1655 (see 2 papers)
GUDX_ECOLI / Q46915 Glucarate dehydratase-related protein; GDH-RP; GlucDRP; EC 4.2.1.- from Escherichia coli (strain K12) (see paper)
gudX / RF|NP_417268 glucarate dehydratase-related protein from Escherichia coli K12
    63% identity, 98% coverage of query (561 bits)

3nfuA / Q1QUN0 Crystal structure of probable glucarate dehydratase from chromohalobacter salexigens dsm 3043 complexed with magnesium
    59% identity, 97% coverage of query (540 bits)

3n6hB / A6VQF6 Crystal structure of mandelate racemase/muconate lactonizing protein from actinobacillus succinogenes 130z complexed with magnesium/sulfate
    59% identity, 97% coverage of query (522 bits)

3pfrA Crystal structure of d-glucarate dehydratase related protein from actinobacillus succinogenes complexed with d-glucarate
    58% identity, 97% coverage of query (519 bits)

3va8A Crystal structure of enolase fg03645.1 (target efi-502278) from gibberella zeae ph-1 complexed with magnesium, formate and sulfate
    36% identity, 96% coverage of query (249 bits)

3vc6A / D6Y7Y6 Crystal structure of enolase tbis_1083(target efi-502310) from thermobispora bispora dsm 43833 complexed with magnesium and formate
    37% identity, 94% coverage of query (235 bits)

4it1D / Q3KB33 Crystal structure of enolase pfl01_3283 (target efi-502286) from pseudomonas fluorescens pf0-1 with bound magnesium, potassium and tartrate
    36% identity, 94% coverage of query (226 bits)

Build an alignment

Build an alignment for RR42_RS04840 and 16 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

4h1zB / Q92ZS5 Crystal structure of putative isomerase from sinorhizobium meliloti, open loop conformation (target efi-502104)
    27% identity, 83% coverage of query (66.2 bits)

C6YXG6 Muconate cycloisomerase (EC 5.5.1.1) from Pseudomonas reinekei (see paper)
    27% identity, 80% coverage of query (62.8 bits)

2og9A Crystal structure of mandelate racemase/muconate lactonizing enzyme from polaromonas sp. Js666
    25% identity, 92% coverage of query (62.4 bits)

3cb3A / Q12GE3 Crystal structure of l-talarate dehydratase from polaromonas sp. Js666 complexed with mg and l-glucarate
    25% identity, 72% coverage of query (62.0 bits)

5olcC / G0L7B8 Crystal structure of the 3,6-anhydro-d-galactonate cycloisomerase from zobellia galactanivorans (see paper)
    25% identity, 82% coverage of query (60.1 bits)

3i6eA / Q5LM96 Crystal structure of muconate lactonizing enzyme from ruegeria pomeroyi.
    24% identity, 75% coverage of query (60.1 bits)

3rcyF Crystal structure of mandelate racemase/muconate lactonizing enzyme- like protein from roseovarius sp. Tm1035
    26% identity, 84% coverage of query (58.5 bits)

3sjnA / A8H9D1 Crystal structure of enolase spea_3858 (target efi-500646) from shewanella pealeana with magnesium bound
    25% identity, 81% coverage of query (55.5 bits)

3fcpA / A6T9N5 Crystal structure of muconate lactonizing enzyme from klebsiella pneumoniae
    27% identity, 83% coverage of query (54.7 bits)

catB / BAE46388.1 cis,cis-muconate cycloisomerase from Rhodococcus sp. AN-22 (see paper)
    25% identity, 81% coverage of query (53.1 bits)

3ozmD Crystal structure of enolase superfamily member from bordetella bronchiseptica complexed with mg, m-xylarate and l-lyxarate
    25% identity, 85% coverage of query (46.2 bits)

3ozmA / A0A0H3LT39 Crystal structure of enolase superfamily member from bordetella bronchiseptica complexed with mg, m-xylarate and l-lyxarate
    25% identity, 85% coverage of query (45.8 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory