Searching for up to 100 curated homologs for RR42_RS05075 FitnessBrowser__Cup4G11:RR42_RS05075 (337 a.a.)
Found high-coverage hits (≥70%) to 50 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
nbaD / Q83V25 2-amino-3-carboxymuconate 6-semialdehyde decarboxylase (EC 4.1.1.45) from Pseudomonas fluorescens (see paper)
Q83V25 aminocarboxymuconate-semialdehyde decarboxylase (EC 4.1.1.45) from Pseudomonas fluorescens (see 2 papers)
nbaD / BAC65312.1 2-amino-3-carboxymuconate 6-semialdehyde decarboxylase from Pseudomonas fluorescens (see paper)
70% identity, 97% coverage of query (495 bits)
7k13C Acmsd in complex with diflunisal derivative 14
70% identity, 97% coverage of query (494 bits)
7k12A Acmsd in complex with diflunisal
70% identity, 97% coverage of query (494 bits)
2hbvA Crystal structure of alpha-amino-beta-carboxymuconate-epsilon- semialdehyde-decarboxylase (acmsd)
70% identity, 97% coverage of query (494 bits)
4eraA / Q83V25 Evidence for a dual role of an active site histidine in alpha-amino- beta-carboxymuconate-epsilon-semialdehyde decarboxylase (see paper)
70% identity, 97% coverage of query (493 bits)
4ergA Evidence for a dual role of an active site histidine in alpha-amino- beta-carboxymuconate-epsilon-semialdehyde decarboxylase
70% identity, 97% coverage of query (493 bits)
ACMSD_MOUSE / Q8R519 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Picolinate carboxylase; EC 4.1.1.45 from Mus musculus (Mouse) (see paper)
Q8R519 aminocarboxymuconate-semialdehyde decarboxylase (EC 4.1.1.45) from Mus musculus (see paper)
41% identity, 97% coverage of query (240 bits)
ACMSD / Q8TDX5 aminocarboxymuconate-semialdehyde decarboxylase (EC 4.1.1.45) from Homo sapiens (see 2 papers)
ACMSD_HUMAN / Q8TDX5 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Picolinate carboxylase; EC 4.1.1.45 from Homo sapiens (Human) (see 2 papers)
Q8TDX5 aminocarboxymuconate-semialdehyde decarboxylase (EC 4.1.1.45) from Homo sapiens (see 5 papers)
40% identity, 97% coverage of query (236 bits)
4ofcA / Q8TDX5 2.0 angstroms x-ray crystal structure of human 2-amino-3- carboxymuconate-6-semialdehye decarboxylase (see paper)
40% identity, 97% coverage of query (235 bits)
7pwyA Structure of human dimeric acmsd in complex with the inhibitor tes- 1025
40% identity, 97% coverage of query (235 bits)
4ih3A 2.5 angstroms x-ray crystal structure of of human 2-amino-3- carboxymuconate-6-semialdehyde decarboxylase in complex with dipicolinic acid
40% identity, 97% coverage of query (235 bits)
2wm1A The crystal structure of human alpha-amino-beta-carboxymuconate- epsilon-semialdehyde decarboxylase in complex with 1,3- dihydroxyacetonephosphate suggests a regulatory link between NAD synthesis and glycolysis
40% identity, 97% coverage of query (235 bits)
ACMSD_RAT / Q8R5M5 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Picolinate carboxylase; EC 4.1.1.45 from Rattus norvegicus (Rat) (see 2 papers)
Q8R5M5 aminocarboxymuconate-semialdehyde decarboxylase (EC 4.1.1.45) from Rattus norvegicus (see 3 papers)
40% identity, 97% coverage of query (234 bits)
nbaD / A4IT47 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase (EC 4.1.1.45) from Geobacillus thermodenitrificans (strain NG80-2) (see paper)
36% identity, 98% coverage of query (213 bits)
7pwyC / Q8TDX5 Structure of human dimeric acmsd in complex with the inhibitor tes- 1025 (see paper)
38% identity, 97% coverage of query (209 bits)
Build an alignment for RR42_RS05075 and 15 homologs with ≥ 30% identity
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praH / C4TP08 5-carboxy-2-hydroxymuconate-6-semialdehyde decarboxylase from Paenibacillus sp. JJ-1b (see 3 papers)
praH / BAH79106.1 5-carboxy-2-hydroxymuconate-6-semialdehyde decarboxylase from Paenibacillus sp. JJ-1b (see paper)
29% identity, 88% coverage of query (133 bits)
4hjwC / E9F0X0 Crystal structure of metarhizium anisopliae idcase in apo form (see paper)
25% identity, 96% coverage of query (94.7 bits)
4qrnA / Q2GA79 High-resolution crystal structure of 5-carboxyvanillate decarboxylase (target efi-505250) from novosphingobium aromaticivorans dsm 12444 complexed with manganese and 4-hydroxy-3-methoxy-5-nitrobenzoic acid
29% identity, 80% coverage of query (92.4 bits)
4infA Crystal structure of amidohydrolase saro_0799 (target efi-505250) from novosphingobium aromaticivorans dsm 12444 with bound calcium
29% identity, 80% coverage of query (92.4 bits)
4hk6A Crystal structure of cordyceps militaris idcase in complex with 5- nitro-uracil
24% identity, 97% coverage of query (91.3 bits)
4hk5D / G3J531 Crystal structure of cordyceps militaris idcase in apo form (see paper)
24% identity, 97% coverage of query (90.9 bits)
4hk7A Crystal structure of cordyceps militaris idcase in complex with uracil
24% identity, 97% coverage of query (90.9 bits)
4lalA Crystal structure of cordyceps militaris idcase d323a mutant in complex with 5-carboxyl-uracil
24% identity, 97% coverage of query (88.2 bits)
ligW2 / Q84IP8 5-carboxyvanillate decarboxylase from Sphingomonas paucimobilis (see 2 papers)
27% identity, 80% coverage of query (83.6 bits)
4icmA / G2IN12 Crystal structure of 5-carboxyvanillate decarboxylase ligw from sphingomonas paucimobilis
28% identity, 93% coverage of query (81.6 bits)
ligW / Q8RJ47 5-carboxyvanillate decarboxylase from Sphingomonas paucimobilis (see 2 papers)
ligW / BAB85806.1 5-carboxyvanillate decarboxylase from Sphingomonas paucimobilis (see 3 papers)
ligW / BAB86295.1 5-carboxyvanillate decarboxylase from Sphingomonas paucimobilis (see paper)
28% identity, 93% coverage of query (81.6 bits)
4ni8A Crystal structure of 5-carboxyvanillate decarboxylase ligw from sphingomonas paucimobilis complexed with mn and 5-methoxyisophtalic acid
28% identity, 93% coverage of query (81.6 bits)
4ng3A Crystal structure of 5-carboxyvanillate decarboxylase from sphingomonas paucimobilis complexed with 4-hydroxy-3-methoxy-5- nitrobenzoic acid
28% identity, 93% coverage of query (81.6 bits)
4l6dA Crystal structure of 5-carboxyvanillate decarboxylase from sphingomonas paucimobilis complexed with vanillic acid
28% identity, 93% coverage of query (81.6 bits)
picC / A0A1X9WE52 3,6-dihydroxypicolinate decarboxylase from Alcaligenes faecalis (see paper)
27% identity, 81% coverage of query (80.9 bits)
GRDC_RHIRD / Q60FX6 Gamma-resorcylate decarboxylase; 2,6-dihydroxybenzoate decarboxylase; Reversible gamma-RA decarboxylase; EC 4.1.1.103 from Rhizobium radiobacter (Agrobacterium tumefaciens) (Agrobacterium radiobacter) (see paper)
Q60FX6 gamma-resorcylate decarboxylase (EC 4.1.1.103) from Agrobacterium tumefaciens (see paper)
27% identity, 80% coverage of query (73.6 bits)
tsdA / Q0SFL6 γ-resorcylate decarboxylase (EC 4.1.1.103) from Rhodococcus jostii (strain RHA1) (see 2 papers)
GRDC_RHOJR / Q0SFL6 Gamma-resorcylate decarboxylase; GRA decarboxylase; 2,6-dihydroxybenzoate decarboxylase; EC 4.1.1.103 from Rhodococcus jostii (strain RHA1) (see paper)
26% identity, 80% coverage of query (73.2 bits)
graF / Q60GU1 γ-resorcylate decarboxylase monomer (EC 4.1.1.103) from Rhizobium sp. (strain MTP-10005) (see 2 papers)
GRDC_RHIS5 / Q60GU1 Gamma-resorcylate decarboxylase; GRDC; Gamma-RDC; 2,6-dihydroxybenzoate decarboxylase; EC 4.1.1.103 from Rhizobium sp. (strain MTP-10005) (see 3 papers)
Q60GU1 gamma-resorcylate decarboxylase (EC 4.1.1.103) from Rhizobium sp. (see 3 papers)
26% identity, 80% coverage of query (72.8 bits)
2dvtA / Q60GU1 Crystal structure of 2,6-dihydroxybenzoate decarboxylase from rhizobium
26% identity, 80% coverage of query (72.4 bits)
2dvxA Crystal structure of 2,6-dihydroxybenzoate decarboxylase complexed with inhibitor 2,3-dihydroxybenzaldehyde
26% identity, 80% coverage of query (72.4 bits)
2dvuA Crystal structure of 2,6-dihydroxybenzoate decarboxylase complexed with 2,6-dihydroxybenzoate
26% identity, 80% coverage of query (72.4 bits)
3nurA / A0A0H3K164 Crystal structure of a putative amidohydrolase from staphylococcus aureus
24% identity, 80% coverage of query (72.0 bits)
GRDC_POLSJ / Q12BV1 Gamma-resorcylate decarboxylase; Gamma-RSD; 2,6-dihydroxybenzoate decarboxylase; 2,6-DHBD; EC 4.1.1.103 from Polaromonas sp. (strain JS666 / ATCC BAA-500) (see paper)
Q12BV1 gamma-resorcylate decarboxylase (EC 4.1.1.103) from Polaromonas sp. JS666 (see paper)
24% identity, 81% coverage of query (72.0 bits)
4qroA / Q12BV1 Crystal structure of dihydroxybenzoic acid decarbboxylase bpro_2061 (target efi-500288) from polaromonas sp. Js666 with bound manganese and an inhibitor, 2-nitroresorcinol
24% identity, 81% coverage of query (72.0 bits)
7wjrA Crystal structure of dihydroxybenzoate decarboxylase mutant a63s from aspergillus oryzae in complex with catechol
24% identity, 81% coverage of query (61.6 bits)
7a19A / P80402 2,3-dihydroxybenzoate decarboxylase of aspergillus oryzae (see paper)
24% identity, 81% coverage of query (61.2 bits)
7bpcA Crystal structure of 2, 3-dihydroxybenzoic acid decarboxylase from fusarium oxysporum in complex with 2,5-dhba
24% identity, 80% coverage of query (59.3 bits)
X0JT48 o-pyrocatechuate decarboxylase (EC 4.1.1.46) from Fusarium odoratissimum NRRL 54006 (see paper)
24% identity, 80% coverage of query (58.9 bits)
6m53B / N1S495 Crystal structure of 2, 3-dihydroxybenzoic acid decarboxylase from fusarium oxysporum (see paper)
24% identity, 80% coverage of query (58.9 bits)
7bp1A Crystal structure of 2, 3-dihydroxybenzoic acid decarboxylase from fusarium oxysporum in complex with catechol
24% identity, 80% coverage of query (58.9 bits)
5vn5C / G2IN02 Crystal structure of ligy from sphingobium sp. Strain syk-6 (see paper)
24% identity, 81% coverage of query (57.0 bits)
6e6iA Crystal structure of 4-methyl hopda bound to ligy from sphingobium sp. Strain syk-6
24% identity, 81% coverage of query (57.0 bits)
6m2iB Structure of the 2-aminoisobutyric acid monooxygenase hydroxylase
24% identity, 81% coverage of query (54.3 bits)
8h41B / P0CT50 Crystal structure of a decarboxylase from trichosporon moniliiforme in complex with o-nitrophenol
24% identity, 71% coverage of query (51.2 bits)
SDC_CUTMO / P0CT50 Salicylate decarboxylase; Salicylic acid decarboxylase; EC 4.1.1.91 from Cutaneotrichosporon moniliiforme (Yeast) (Trichosporon moniliiforme) (see paper)
P0CT50 salicylate decarboxylase (EC 4.1.1.91) from Cutaneotrichosporon moniliiforme (see paper)
24% identity, 71% coverage of query (51.2 bits)
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Lawrence Berkeley National Laboratory