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Searching for up to 100 curated homologs for RR42_RS05540 FitnessBrowser__Cup4G11:RR42_RS05540 (792 a.a.)

Found high-coverage hits (≥70%) to 36 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

7arcG Cryo-em structure of polytomella complex-i (peripheral arm) (see paper)
    37% identity, 80% coverage of query (398 bits)

NDUS1_BOVIN / P15690 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial; Complex I-75kD; CI-75kD; EC 7.1.1.2 from Bos taurus (Bovine) (see 3 papers)
TC 3.D.1.6.1 / P15690 75 (NuoG), component of The vertebrate H+-translocating NADH dehydrogenase (NDH) complex (45 subunits) from Bos taurus (Bovine) (see paper)
    36% identity, 87% coverage of query (394 bits)

7qsoG / P15690 Bovine complex i in lipid nanodisc, state 3 (slack) (see paper)
    36% identity, 87% coverage of query (394 bits)

at5g37510 / Q9FGI6 NADH-ubiquinone oxidoreductase 75 kDa subunit (EC 7.1.1.2) from Arabidopsis thaliana (see paper)
TC 3.D.1.6.3 / Q9FGI6 81.5 (NuoG), component of The higher plant H+ translocating NADH dehydrogenase (NDH) complex (41 subunits; 23 included here) from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
    37% identity, 83% coverage of query (392 bits)

7a23C / Q9FGI6 Plant mitochondrial respiratory complex i (see paper)
    37% identity, 83% coverage of query (392 bits)

7zm7A / G0RYA1 Cryoem structure of mitochondrial complex i from chaetomium thermophilum (inhibited by ddm) (see paper)
    37% identity, 82% coverage of query (392 bits)

8bedG Cryo-em structure of the arabidopsis thaliana i+iii2 supercomplex (ci peripheral tip)
    37% identity, 83% coverage of query (392 bits)

NDUS1_MOUSE / Q91VD9 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial; Complex I-75kD; CI-75kD; EC 7.1.1.2 from Mus musculus (Mouse) (see 2 papers)
    36% identity, 87% coverage of query (391 bits)

NDUFS1 / P28331 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial from Homo sapiens (see 3 papers)
NDUS1_HUMAN / P28331 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial; Complex I-75kD; CI-75kD; EC 7.1.1.2 from Homo sapiens (Human) (see 4 papers)
    36% identity, 87% coverage of query (390 bits)

7v2cM Active state complex i from q10 dataset
    35% identity, 87% coverage of query (389 bits)

TC 3.D.1.6.4 / Q6UKY6 75 (NuoG), component of The green algal H+ translocating NADH dehydrogenase (NDH) complex (42 subunits; 33 included here) from Chlamydomonas reinhardtii
    36% identity, 89% coverage of query (387 bits)

5gupG structure of mammalian respiratory supercomplex I1III2IV1
    36% identity, 87% coverage of query (387 bits)

TC 3.D.1.6.2 / P24918 78 (NuoG), component of The fungal H+ translocating NADH dehydrogenase (NDH) complex (38 subunits; 35 included here) from Neurospora crassa (see 3 papers)
    38% identity, 83% coverage of query (386 bits)

nuam / CAB65519.1 NUAM protein from Yarrowia lipolytica (see paper)
    35% identity, 83% coverage of query (385 bits)

7b0nG / Q9UUU3 3.7-angstrom structure of Yarrowia lipolytica complex I with an R121M mutation in NUCM. (see paper)
    35% identity, 83% coverage of query (385 bits)

NDUS1_CANAL / A0A1D8PU51 NADH-ubiquinone oxidoreductase 78 kDa subunit, mitochondrial; EC 7.1.1.2 from Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) (see 2 papers)
    35% identity, 83% coverage of query (375 bits)

8gyms1 / Q23KA9 8gyms1 (see paper)
    35% identity, 83% coverage of query (374 bits)

8eszS1 / Q94511 8eszS1 (see paper)
    37% identity, 83% coverage of query (370 bits)

NQO3_PARDE / P29915 NADH-quinone oxidoreductase chain 3; NADH dehydrogenase I, chain 3; NDH-1, chain 3; EC 7.1.1.- from Paracoccus denitrificans (see 2 papers)
TC 3.D.1.2.1 / P29915 NQO3, component of NADH dehydrogenase I from Paracoccus denitrificans (see 4 papers)
NQO3 / AAA25587.1 NADH dehydrogenase from Paracoccus denitrificans (see paper)
    37% identity, 79% coverage of query (367 bits)

8e9hG / A0QU30 Mycobacterial respiratory complex i, fully-inserted quinone (see paper)
    33% identity, 97% coverage of query (294 bits)

NUOG_MYCTU / P9WIV9 NADH-quinone oxidoreductase subunit G; NADH dehydrogenase I subunit G; NDH-1 subunit G; EC 7.1.1.- from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 3 papers)
    32% identity, 94% coverage of query (290 bits)

SFRA_GEOSK / D7AF63 NADPH-Fe(3+) oxidoreductase subunit alpha; Soluble Fe(3+) reductase alpha subunit; EC 1.-.-.- from Geobacter sulfurreducens (strain DL-1 / KN400) (see paper)
SFRA_GEOSL / Q74FU6 NADPH-Fe(3+) oxidoreductase subunit alpha; Soluble Fe(3+) reductase alpha subunit; EC 1.-.-.- from Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA) (see 2 papers)
    32% identity, 80% coverage of query (285 bits)

Build an alignment

Build an alignment for RR42_RS05540 and 22 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

fdhA-II / CAC39239.1 FdhA-II protein from Peptoclostridium acidaminophilum (see paper)
    29% identity, 83% coverage of query (268 bits)

TC 3.D.1.5.1 / Q746S9 NuoG aka GSU3439, component of Proton-translocating NADH dehydrogenase I from Geobacter sulfurreducens (see paper)
    32% identity, 77% coverage of query (258 bits)

NUOG_PSEFL / Q9KGW3 NADH-quinone oxidoreductase subunit G; NADH dehydrogenase I subunit G; NDH-1 subunit G; EC 7.1.1.- from Pseudomonas fluorescens (see paper)
    30% identity, 88% coverage of query (245 bits)

7nyrG Respiratory complex i from escherichia coli - conformation 1
    28% identity, 88% coverage of query (235 bits)

NuoG / b2283 NADH:quinone oxidoreductase subunit G from Escherichia coli K-12 substr. MG1655 (see 15 papers)
nuoG / P33602 NADH:quinone oxidoreductase subunit G from Escherichia coli (strain K12) (see 14 papers)
NUOG_ECOLI / P33602 NADH-quinone oxidoreductase subunit G; NADH dehydrogenase I subunit G; NDH-1 subunit G; NUO7; EC 7.1.1.- from Escherichia coli (strain K12) (see paper)
TC 3.D.1.1.1 / P33602 NUOG aka B2283, component of NADH dehydrogenase I, NuoA-N from Escherichia coli (see 7 papers)
    28% identity, 88% coverage of query (234 bits)

7awtG / P33602 E. Coli nadh quinone oxidoreductase hydrophilic arm (see paper)
    28% identity, 87% coverage of query (233 bits)

4hea3 / Q56223 Crystal structure of the entire respiratory complex i from thermus thermophilus (see paper)
    31% identity, 77% coverage of query (231 bits)

3i9vC Crystal structure of the hydrophilic domain of respiratory complex i from thermus thermophilus, oxidized, 2 mol/asu
    31% identity, 77% coverage of query (231 bits)

3i9v3 Crystal structure of the hydrophilic domain of respiratory complex i from thermus thermophilus, oxidized, 2 mol/asu
    31% identity, 77% coverage of query (231 bits)

2ybb3 Fitted model for bovine mitochondrial supercomplex i1iii2iv1 by single particle cryo-em (emd-1876)
    31% identity, 77% coverage of query (231 bits)

NQO3_THET8 / Q56223 NADH-quinone oxidoreductase subunit 3; NADH dehydrogenase I chain 3; NDH-1 subunit 3; EC 7.1.1.- from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see 2 papers)
TC 3.D.1.3.1 / Q56223 Nqo3, component of NADH Dehydrogenase, NDH (Baradaran et al. 2013).  The x-ray structures of various complexes have been solved, and a coupling mechanism involving long range conformational changes has been proposed from Thermus thermophilus (see 4 papers)
    30% identity, 77% coverage of query (227 bits)

Q84FW1 formate dehydrogenase (EC 1.17.1.9) from Methylorubrum extorquens (see paper)
    25% identity, 82% coverage of query (199 bits)

7t30A / I4BYB4 Structure of electron bifurcating ni-fe hydrogenase complex hydabcsl in fmn/NAD(h) bound state (see paper)
    26% identity, 78% coverage of query (171 bits)

8oh5C / A0A0U1KYI6 Cryo-em structure of the electron bifurcating transhydrogenase stnabc complex from sporomusa ovata (state 2) (see paper)
    26% identity, 75% coverage of query (125 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory