Searching for up to 100 curated homologs for RR42_RS06495 FitnessBrowser__Cup4G11:RR42_RS06495 (368 a.a.)

Found high-coverage hits (≥70%) to 13 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

L2HDH_ACHAE / A0A0M7LBC1 L-2-hydroxyglutarate dehydrogenase; EC 1.1.99.2 from Achromobacter aegrifaciens (see paper)
    65% identity, 99% coverage of query (470 bits)

3dmeA / Q7VU70 Crystal structure of conserved exported protein from bordetella pertussis. Northeast structural genomics target ber141
    63% identity, 99% coverage of query (456 bits)

L2HDH_ACCRE / A0A011QK89 L-2-hydroxyglutarate dehydrogenase; EC 1.1.99.2 from Accumulibacter regalis (see paper)
    63% identity, 97% coverage of query (452 bits)

L2HDH_ARATH / Q9LES4 L-2-hydroxyglutarate dehydrogenase, mitochondrial; EC 1.1.99.2 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
    50% identity, 99% coverage of query (393 bits)

LHGD_SALHO / A0A5Y6MCT2 L-2-hydroxyglutarate dehydrogenase; L2HG dehydrogenase; L2HG:quinone oxidoreductase; EC 1.1.5.13 from Salmonella houtenae (see paper)
    30% identity, 92% coverage of query (127 bits)

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Build an alignment for RR42_RS06495 and 5 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

GLPDH_CALMK / A0A0R3K2G2 Glycerol 3-phosphate dehydrogenase; EC 1.1.99.- from Caloramator mitchellensis (see paper)
    27% identity, 99% coverage of query (123 bits)

L2HDH_HUMAN / Q9H9P8 L-2-hydroxyglutarate dehydrogenase, mitochondrial; Duranin; EC 1.1.99.2 from Homo sapiens (Human) (see 4 papers)
Q9H9P8 L-2-hydroxyglutarate dehydrogenase (EC 1.1.99.2) from Homo sapiens (see 2 papers)
    32% identity, 70% coverage of query (120 bits)

8w7fB / Q9VJ28 Structure of drosophila melanogaster l-2-hydroxyglutarate dehydrogenase bound with fad and a sulfate ion (see paper)
    29% identity, 95% coverage of query (118 bits)

LhgD / b2660 L-2-hydroxyglutarate dehydrogenase (EC 1.1.5.13) from Escherichia coli K-12 substr. MG1655 (see 9 papers)
lhgD / P37339 L-2-hydroxyglutarate dehydrogenase (EC 1.1.5.13) from Escherichia coli (strain K12) (see 7 papers)
LHGD_ECOLI / P37339 L-2-hydroxyglutarate dehydrogenase; L2HG dehydrogenase; L2HG:quinone oxidoreductase; EC 1.1.5.13 from Escherichia coli (strain K12) (see 3 papers)
ygaF / RF|NP_417146 uncharacterized protein ygaF from Escherichia coli K12 (see 2 papers)
    28% identity, 92% coverage of query (117 bits)

8w78A Structure of drosophila melanogaster l-2-hydroxyglutarate dehydrogenase in complex with fad and 2-oxoglutarate
    29% identity, 95% coverage of query (117 bits)

LHGD_ECOLU / B7N6P4 L-2-hydroxyglutarate dehydrogenase; L2HG dehydrogenase; L2HG:quinone oxidoreductase; EC 1.1.5.13 from Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC) (see paper)
    28% identity, 92% coverage of query (116 bits)

lhgO / Q88IT9 (S)-2-hydroxyglutarate oxidase from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see 2 papers)
    27% identity, 92% coverage of query (103 bits)

Q70GP9 glycerol-3-phosphate oxidase (EC 1.1.3.21) from Mycoplasma mycoides subsp. mycoides (see paper)
glpO glycerol-3-phosphate oxidase; EC 1.1.3.21 from Mycoplasma mycoides subsp. mycoides SC (see paper)
    27% identity, 74% coverage of query (70.1 bits)

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