Searching for up to 100 curated homologs for RR42_RS11100 FitnessBrowser__Cup4G11:RR42_RS11100 (509 a.a.)
Found high-coverage hits (≥70%) to 67 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
CadR / b2156 lysine:H+ symporter from Escherichia coli K-12 substr. MG1655 (see 15 papers)
lysP / P25737 lysine:H+ symporter from Escherichia coli (strain K12) (see 13 papers)
LYSP_ECOLI / P25737 Lysine-specific permease LysP; Lysine transporter LysP; Trigger transporter LysP from Escherichia coli (strain K12) (see 7 papers)
TC 2.A.3.1.2 / P25737 Lysine:H+ symporter. Forms a stable complex with CadC to allow lysine-dependent adaptation to acidic stress (Rauschmeier et al. 2013). The Salmonella orthologue is 95% identical to the E. coli protein and is highly specific for Lysine. Residues involved in lysine binding have been identified from Escherichia coli (see 5 papers)
lysP lysine-specific permease from Escherichia coli K12 (see 5 papers)
66% identity, 95% coverage of query (662 bits)
HISP_LACLM / A2RI97 Histidine permease HisP from Lactococcus lactis subsp. cremoris (strain MG1363) (see paper)
48% identity, 94% coverage of query (461 bits)
LYSP_LACLM / A2RNZ6 Lysine-specific permease LysP; Lysine transporter LysP from Lactococcus lactis subsp. cremoris (strain MG1363) (see paper)
47% identity, 94% coverage of query (453 bits)
TC 2.A.3.1.18 / K7VV21 The lysine specific transporter, LysP of 488 aas and 12 TMSs from Lactococcus lactis subsp. cremoris UC509.9
47% identity, 94% coverage of query (453 bits)
ROCE_BACSU / P39137 Amino-acid permease RocE from Bacillus subtilis (strain 168) (see paper)
TC 2.A.3.1.11 / P39137 L-Arginine permease, RocE from Bacillus subtilis (see 3 papers)
42% identity, 91% coverage of query (357 bits)
CAN1_YEAST / P04817 Arginine permease CAN1; Canavanine resistance protein 1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 12 papers)
TC 2.A.3.10.4 / P04817 Arginine permease from Saccharomyces cerevisiae (Baker's yeast) (see 6 papers)
CAN1 / RF|NP_010851.1 arginine permease from Saccharomyces cerevisiae
37% identity, 92% coverage of query (330 bits)
GAP2_CANAL / A0A1D8PK89 General amino-acid permease GAP2 from Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) (see 6 papers)
TC 2.A.3.10.24 / Q59YT0 General amino and permease and transceptor, GAP2. Transports all amino acids including citruline and eight tested toxic amino acid derivatives from Candida albicans (see paper)
37% identity, 96% coverage of query (318 bits)
CAN1_CANGA / Q6FNY1 Arginine permease CAN1 from Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus) (see paper)
37% identity, 94% coverage of query (314 bits)
LYP1_YEAST / P32487 Lysine-specific permease from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
TC 2.A.3.10.10 / P32487 Lysine permease of 611 aas and 13 putative TMSs, Lyp1 from Saccharomyces cerevisiae (Baker's yeast) (see 9 papers)
LYP1 / GI|1302328 lysine-specific permease from Saccharomyces cerevisiae
36% identity, 94% coverage of query (314 bits)
agtA amino acid transporter from Emericella nidulans (see 2 papers)
34% identity, 98% coverage of query (314 bits)
YQD2_SCHPO / Q9C0V0 Probable amino-acid permease PB1C11.02 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
36% identity, 93% coverage of query (309 bits)
MmuP / b0260 CP4-6 prophage; S-methyl-L-methionine transporter from Escherichia coli K-12 substr. MG1655 (see 3 papers)
mmuP / Q47689 CP4-6 prophage; S-methyl-L-methionine transporter from Escherichia coli (strain K12) (see 2 papers)
TC 2.A.3.1.10 / Q47689 S-Methylmethionine permease, MmuP from Escherichia coli (see 3 papers)
39% identity, 84% coverage of query (302 bits)
CAN2_CANAL / Q59WU0 Probable lysine/arginine permease CAN2; Basic amino acids permease CAN2 from Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) (see 7 papers)
38% identity, 89% coverage of query (295 bits)
TC 2.A.3.10.17 / Q8J266 General amino acid uptake permease, GAP1 from Hebeloma cylindrosporum (see paper)
35% identity, 95% coverage of query (294 bits)
TC 2.A.3.10.28 / O60170 Probable amino-acid permease Meu22 (Meiotic expression up-regulated protein 22) from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (see 2 papers)
32% identity, 95% coverage of query (293 bits)
GAP3_CANAL / A0A1D8PN88 Amino-acid permease GAP3 from Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) (see 5 papers)
32% identity, 95% coverage of query (292 bits)
ALP1_YEAST / P38971 Basic amino-acid permease from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
TC 2.A.3.10.11 / P38971 Basic amino acid permease from Saccharomyces cerevisiae (Baker's yeast) (see 5 papers)
ALP1 / RF|NP_014129.1 basic amino-acid permease from Saccharomyces cerevisiae
36% identity, 94% coverage of query (291 bits)
CAN1_CANAL / A0A1D8PPI5 Lysine/arginine permease CAN1; Basic amino acids permease CAN1 from Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) (see 7 papers)
37% identity, 90% coverage of query (291 bits)
GAP1_CANAL / Q5AG77 Amino-acid permease GAP1 from Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) (see 9 papers)
TC 2.A.3.10.23 / Q5AG77 Amino acid permease, GAP1. Transports Arg, Met, Leu and Phe from Candida albicans (see 2 papers)
GAP1 general amino acid permease from Candida albicans (see 3 papers)
34% identity, 94% coverage of query (290 bits)
TC 2.A.3.10.20 / P43059 The high affinity basic amino acid (Arg, Lys, His) transporter, Can1 from Candida albicans (Yeast) (see paper)
37% identity, 90% coverage of query (289 bits)
GAP4_CANAL / Q59WB3 S-adenosylmethionine permease GAP4; SAM permease; Amino-acid permease GAP4 from Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) (see 6 papers)
TC 2.A.3.10.25 / Q59WB3 Arginine transporter, GAP4 from Candida albicans (see paper)
GAP4 potential general amino acid permease from Candida albicans (see paper)
36% identity, 95% coverage of query (287 bits)
CH_124074 putative amino-acid permease inda1 (T. harzianum) from Magnaporthe grisea 70-15 (see paper)
34% identity, 94% coverage of query (287 bits)
CAN3_CANAL / A0A1D8PPG4 Probable lysine/arginine permease CAN3; Basic amino acids permease CAN3 from Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) (see 2 papers)
36% identity, 90% coverage of query (287 bits)
YI26_SCHPO / Q9P768 Uncharacterized amino-acid permease P7G5.06 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
per1 plasma membrane amino acid permease Per1 from Schizosaccharomyces pombe (see 2 papers)
33% identity, 91% coverage of query (286 bits)
DIP5_YEAST / P53388 Dicarboxylic amino acid permease from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
TC 2.A.3.10.13 / P53388 Dicarboxylic amino acid permease from Saccharomyces cerevisiae (Baker's yeast) (see 7 papers)
DIP5 / RF|NP_015058.1 dicarboxylic amino acid permease from Saccharomyces cerevisiae
33% identity, 93% coverage of query (285 bits)
GABP_BACSU / P46349 Gamma-aminobutyric acid permease; GABA permease; 4-aminobutyrate permease; Gamma-aminobutyrate permease; Proline transporter GabP from Bacillus subtilis (strain 168) (see 3 papers)
TC 2.A.3.1.5 / P46349 β-alanine/γ-aminobutyrate/proline/3,4-dehydroproline:H+ symporter, GabP from Bacillus subtilis (see 4 papers)
gabP / AAC44641.1 gamma-aminobutyrate permease from Bacillus subtilis (see 2 papers)
37% identity, 91% coverage of query (280 bits)
gabP / AAB62306.1 GabP from Bacillus subtilis (see 4 papers)
37% identity, 91% coverage of query (279 bits)
CAT1_SCHPO / Q9URZ4 Cationic amino acid transporter 1 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
31% identity, 95% coverage of query (274 bits)
TC 2.A.3.10.21 / Q9URZ4 The basic amino acid (canavanine sensitivity) transporter, Cat1 from Schizosaccharomyces pombe (Fission yeast) (see 2 papers)
cat1 / RF|NP_595008.2 uncharacterized amino-acid permease C869.11 from Schizosaccharomyces pombe (see 3 papers)
31% identity, 95% coverage of query (274 bits)
GAP5_CANAL / A0A1D8PMB1 Amino-acid permease GAP5 from Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) (see 2 papers)
33% identity, 92% coverage of query (274 bits)
AAT1_SCHPO / Q9P5N2 Amino acid transporter 1 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
32% identity, 91% coverage of query (274 bits)
GAP1_YEAST / P19145 General amino-acid permease GAP1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 19 papers)
TC 2.A.3.10.2 / P19145 General amino acid permease (all L-amino acids and some D-amino acids as well as β-alanine, polyamines and GABA) from Saccharomyces cerevisiae (Baker's yeast) (see 8 papers)
GAP1 / RF|NP_012965.1 general amino-acid permease GAP1 from Saccharomyces cerevisiae
34% identity, 94% coverage of query (273 bits)
YHE1_SCHPO / Q9HDV2 Uncharacterized amino-acid permease PB2B2.01 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
33% identity, 97% coverage of query (268 bits)
RR42_RS28305 L-threonine:H+ symporter from Cupriavidus basilensis FW507-4G11
35% identity, 93% coverage of query (265 bits)
prnB / GB|CAA56191.1 proline-specific permease (proline transport protein) from Emericella nidulans (see 5 papers)
34% identity, 93% coverage of query (264 bits)
AAS52655.3 AEL030Wp from Eremothecium gossypii ATCC 10895 (see paper)
32% identity, 91% coverage of query (264 bits)
PUT4_YEAST / P15380 Proline-specific permease from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
TC 2.A.3.10.3 / P15380 Proline permease from Saccharomyces cerevisiae (Baker's yeast) (see 4 papers)
PUT4 / RF|NP_014993.1 proline-specific permease from Saccharomyces cerevisiae
32% identity, 93% coverage of query (264 bits)
PUT4_SCHPO / Q9URZ3 Probable proline-specific permease put4 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
32% identity, 91% coverage of query (257 bits)
GAP6_CANAL / A0A1D8PNP3 Amino-acid permease GAP6 from Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) (see 5 papers)
32% identity, 94% coverage of query (253 bits)
TC 2.A.3.10.26 / Q59NZ6 General amino acid porter, GAP6. Transports almost all amino acids tested except arginine and citruline from Candida albicans (see paper)
32% identity, 94% coverage of query (253 bits)
PheP / b0576 phenylalanine:H+ symporter PheP from Escherichia coli K-12 substr. MG1655 (see 3 papers)
pheP / P24207 phenylalanine:H+ symporter PheP from Escherichia coli (strain K12) (see 3 papers)
PHEP_ECOLI / P24207 Phenylalanine-specific permease; Phenylalanine:H(+) symporter PheP from Escherichia coli (strain K12) (see 6 papers)
TC 2.A.3.1.1 / P24207 Phenylalanine:H+ symporter, PheP of 458 aas and 12 established TMSs from Escherichia coli (see 6 papers)
35% identity, 86% coverage of query (252 bits)
AO356_17670 L-alanine and D-alanine permease from Pseudomonas fluorescens FW300-N2C3
36% identity, 91% coverage of query (252 bits)
TAT2_YEAST / P38967 Tryptophan permease; Tryptophan amino acid transporter from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 3 papers)
TC 2.A.3.10.8 / P38967 Tryptophan permease, Tat2. Regulated via endocytosis by ATP-binding Cassette Transporters, Pdr5 (3.A.1.205.1) and Yor1 (3.A.208.3) as well as a seven-transmembrane protein, RSB1 (9.A.27.1.2) from Saccharomyces cerevisiae (Baker's yeast) (see 7 papers)
TAT2 / RF|NP_014622.1 tryptophan permease from Saccharomyces cerevisiae
34% identity, 84% coverage of query (249 bits)
AO353_16120 D-alanine and L-alanine transporter from Pseudomonas fluorescens FW300-N2E3
36% identity, 92% coverage of query (248 bits)
TC 2.A.3.10.22 / Q2VQZ4 Arbuscular mycorrhizal fungal proline:H+ symporter, AAP1 (binds and probably transports nonpolar, hydrophobic amino acids) from Glomus mosseae (see paper)
32% identity, 94% coverage of query (248 bits)
MMP1_YEAST / Q12372 S-methylmethionine permease 1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
TC 2.A.3.10.16 / Q12372 S-methylmethionine uptake permease, Mmp1 from Saccharomyces cerevisiae (Baker's yeast) (see 4 papers)
MMP1 / RF|NP_013039.1 S-methylmethionine permease 1 from Saccharomyces cerevisiae
32% identity, 90% coverage of query (247 bits)
AroR / b0112 aromatic amino acid:H+ symporter AroP from Escherichia coli K-12 substr. MG1655 (see 5 papers)
aroP / P15993 aromatic amino acid:H+ symporter AroP from Escherichia coli (strain K12) (see 6 papers)
AROP_ECOLI / P15993 Aromatic amino acid transport protein AroP; Aromatic amino acid:H(+) symporter AroP; General aromatic amino acid permease; General aromatic transport system from Escherichia coli (strain K12) (see 8 papers)
TC 2.A.3.1.3 / P15993 Aromatic amino acid:H+ symporter, AroP of 457 aas and 12 TMSs (Cosgriff and Pittard 1997). Transports phenylalanine, tyrosine and tryptophan from Escherichia coli (see 6 papers)
36% identity, 81% coverage of query (246 bits)
PS417_05405 L-alanine and D-alanine permease from Pseudomonas simiae WCS417
36% identity, 82% coverage of query (245 bits)
AO353_05930 L-tryptophan transporter from Pseudomonas fluorescens FW300-N2E3
33% identity, 92% coverage of query (245 bits)
YifK / b3795 putative transporter YifK from Escherichia coli K-12 substr. MG1655 (see 5 papers)
thrP / P27837 threonine/serine:H+ symporter ThrP from Escherichia coli (strain K12) (see 5 papers)
36% identity, 86% coverage of query (244 bits)
Build an alignment for RR42_RS11100 and 50 homologs with ≥ 30% identity
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HIP1_YEAST / P06775 Histidine permease from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
TC 2.A.3.10.1 / P06775 High affinity histidine permease (also implicated in Mn2+ efflux; Co2+, Ni2+, Zn2+ and Cu2+ uptake) from Saccharomyces cerevisiae (Baker's yeast) (see 5 papers)
HIP1 / GI|1323339 histidine permease from Saccharomyces cerevisiae
29% identity, 95% coverage of query (243 bits)
AGP1_YEAST / P25376 General amino acid permease AGP1; Asparagine/glutamine permease from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 8 papers)
TC 2.A.3.10.7 / P25376 Asn/Gln permease from Saccharomyces cerevisiae (Baker's yeast) (see 13 papers)
AGP1 / RF|NP_009905.3 general amino acid permease AGP1 from Saccharomyces cerevisiae
29% identity, 91% coverage of query (243 bits)
PfGW456L13_4291 L-tryptophan transporter from Pseudomonas fluorescens GW456-L13
36% identity, 84% coverage of query (242 bits)
RR42_RS33495 L-phenylalanine:H+ symporter AroP from Cupriavidus basilensis FW507-4G11
35% identity, 91% coverage of query (239 bits)
AO353_12275 histidine permease from Pseudomonas fluorescens FW300-N2E3
36% identity, 82% coverage of query (238 bits)
GNP1_YEAST / P48813 High-affinity glutamine permease from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 5 papers)
TC 2.A.3.10.5 / P48813 High affinity glutamine permease from Saccharomyces cerevisiae (Baker's yeast) (see 12 papers)
GNP1 / GI|927778 high-affinity glutamine permease from Saccharomyces cerevisiae
29% identity, 92% coverage of query (237 bits)
SAM3_YEAST / Q08986 S-adenosylmethionine permease SAM3; S-adenosylmethionine metabolism protein 3 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 3 papers)
TC 2.A.3.10.15 / Q08986 S-adenosylmethionine uptake permease, SAM3 (also takes up polyamines, glutamate, lysine and the toxic S-adenosylmethionine analogue sinefungin) from Saccharomyces cerevisiae (Baker's yeast) (see 6 papers)
SAM3 / RF|NP_015049.1 S-adenosylmethionine permease SAM3 from Saccharomyces cerevisiae
34% identity, 90% coverage of query (230 bits)
AO356_18530 L-tyrosine transporter from Pseudomonas fluorescens FW300-N2C3
35% identity, 83% coverage of query (229 bits)
H281DRAFT_04042 phenylacetate transporter from Paraburkholderia bryophila 376MFSha3.1
35% identity, 81% coverage of query (229 bits)
isp5 / RF|NP_595000.1 amino acid permease Isp5 from Schizosaccharomyces pombe (see 2 papers)
30% identity, 93% coverage of query (228 bits)
TC 2.A.3.1.6 / P37460 Proline-specific permease (ProY) from Salmonella typhimurium (see 2 papers)
35% identity, 80% coverage of query (225 bits)
SSY1_YEAST / Q03770 SPS-sensor component SSY1; Amino-acid permease homolog SSY1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 9 papers)
TC 2.A.3.10.12 / Q03770 Leucine sensor/transcription factor. Mutants hyper- and hyposensitive to inducer (Poulsen et al., 2008) suggest a sensor mechanism involving outward and inward facing conformations from Saccharomyces cerevisiae (Baker's yeast) (see 12 papers)
SSY1 / RF|NP_010444.1 amino-acid permease SSY1 from Saccharomyces cerevisiae (see paper)
28% identity, 92% coverage of query (179 bits)
6f34A / Q5L1G5 Crystal structure of a bacterial cationic amino acid transporter (cat) homologue bound to arginine. (see paper)
27% identity, 83% coverage of query (64.7 bits)
5oqtA Crystal structure of a bacterial cationic amino acid transporter (cat) homologue
27% identity, 83% coverage of query (62.4 bits)
6f2wA / A8UCQ5 Bacterial asc transporter crystal structure in open to in conformation (see paper)
21% identity, 86% coverage of query (56.2 bits)
LAT2_MOUSE / Q9QXW9 Large neutral amino acids transporter small subunit 2; L-type amino acid transporter 2; mLAT2; Solute carrier family 7 member 8 from Mus musculus (Mouse) (see 6 papers)
24% identity, 77% coverage of query (53.5 bits)
STET_BACSU / O34739 Serine/threonine exchanger SteT from Bacillus subtilis (strain 168) (see paper)
TC 2.A.3.8.12 / O34739 The Ser/Thr exchange transporter (SteT) (also transports aromatic amino acids with lower efficiency) (Reig et al., 2007). The substrate-bound state of SteT shows increased conformational flexibility and kinetic stability, enabling transport of substrate across the cell membrane (Bippes et al. 2009). TMS8 sculpts the substrate-binding site and undergoes conformational changes during the transport cycle of SteT (Bartoccioni et al., 2010). Mutations allow substrate binding but not translocation. Other mutations stabilize the protein and result in higher production levels from Bacillus subtilis (see 2 papers)
22% identity, 82% coverage of query (45.1 bits)
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