Searching for up to 100 curated homologs for RR42_RS12540 FitnessBrowser__Cup4G11:RR42_RS12540 (436 a.a.)

Found high-coverage hits (≥70%) to 20 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

hom / AAF21129.1 homoserine dehydrogenase from Methylobacillus flagellatus (see paper)
    73% identity, 100% coverage of query (648 bits)

DHOM_NEIG1 / Q5F8J4 NAD(+)-dependent homoserine dehydrogenase; NAD(+)-dependent HSD; NgHSD; EC 1.1.1.3 from Neisseria gonorrhoeae (strain ATCC 700825 / FA 1090) (see paper)
    61% identity, 100% coverage of query (509 bits)

Ga0059261_2711 homoserine dehydrogenase (EC 1.1.1.3) from Sphingomonas koreensis DSMZ 15582
    44% identity, 97% coverage of query (318 bits)

DvMF_1412 homoserine dehydrogenase (EC 1.1.1.3) from Desulfovibrio vulgaris Miyazaki F
    44% identity, 98% coverage of query (318 bits)

D8WXQ1 homoserine dehydrogenase (EC 1.1.1.3) from Bacillus methanolicus (see paper)
    39% identity, 99% coverage of query (316 bits)

DHOM_BACSU / P19582 Homoserine dehydrogenase; HDH; EC 1.1.1.3 from Bacillus subtilis (strain 168) (see paper)
P19582 homoserine dehydrogenase (EC 1.1.1.3) from Bacillus subtilis (see paper)
    37% identity, 99% coverage of query (288 bits)

Q56R01 homoserine dehydrogenase (EC 1.1.1.3) from Streptomyces clavuligerus (see paper)
    39% identity, 99% coverage of query (285 bits)

DHOM_CORGL / P08499 Homoserine dehydrogenase; HDH; EC 1.1.1.3 from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see 2 papers)
P08499 homoserine dehydrogenase (EC 1.1.1.3) from Corynebacterium glutamicum (see 2 papers)
    39% identity, 99% coverage of query (284 bits)

6dzsA / K5BJC9 Mycobacterial homoserine dehydrogenase thra in complex with NADP
    39% identity, 99% coverage of query (265 bits)

A0A0H2WVX4 homoserine dehydrogenase (EC 1.1.1.3) from Staphylococcus aureus (see 2 papers)
    40% identity, 78% coverage of query (263 bits)

DHOM_LACLC / P52985 Homoserine dehydrogenase; HDH; EC 1.1.1.3 from Lactococcus lactis subsp. cremoris (Streptococcus cremoris) (see paper)
    35% identity, 88% coverage of query (249 bits)

P46806 homoserine dehydrogenase (EC 1.1.1.3) from Mycobacterium leprae (see paper)
    37% identity, 99% coverage of query (242 bits)

4pg7A / A0A0M3KKV6 Crystal structure of s. Aureus homoserine dehydrogenase at ph7.5 (see paper)
    38% identity, 78% coverage of query (233 bits)

D8WXQ2 homoserine dehydrogenase (EC 1.1.1.3) from Bacillus methanolicus (see paper)
    37% identity, 78% coverage of query (227 bits)

Q9WZ17 homoserine dehydrogenase (EC 1.1.1.3); aspartate kinase (EC 2.7.2.4) from Thermotoga maritima (see paper)
    40% identity, 72% coverage of query (203 bits)

Q5SL04 homoserine dehydrogenase (EC 1.1.1.3) from Thermus thermophilus (see paper)
6a0tB / Q5SL04 Homoserine dehydrogenase k99a mutant from thermus thermophilus hb8 complexed with hse and NADP+ (see paper)
    35% identity, 75% coverage of query (134 bits)

6a0sA Homoserine dehydrogenase from thermus thermophilus hb8 complexed with hse and NADPH
    35% identity, 75% coverage of query (133 bits)

2ejwA Homoserine dehydrogenase from thermus thermophilus hb8
    35% identity, 75% coverage of query (133 bits)

Build an alignment

Build an alignment for RR42_RS12540 and 18 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

O58802 homoserine dehydrogenase (EC 1.1.1.3) from Pyrococcus horikoshii (see paper)
4xb1A / O58802 Hyperthermophilic archaeal homoserine dehydrogenase in complex with NADPH (see paper)
    26% identity, 72% coverage of query (103 bits)

4xb2A Hyperthermophilic archaeal homoserine dehydrogenase mutant in complex with NADPH
    26% identity, 72% coverage of query (103 bits)

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