Searching for up to 100 curated homologs for RR42_RS14485 FitnessBrowser__Cup4G11:RR42_RS14485 (483 a.a.)
Found high-coverage hits (≥70%) to 16 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
PRPD_CUPNE / Q937N6 2-methylcitrate dehydratase; 2-MC dehydratase; Aconitate hydratase; ACN; Aconitase; EC 4.2.1.79; EC 4.2.1.3 from Cupriavidus necator (Alcaligenes eutrophus) (Ralstonia eutropha) (see paper)
86% identity, 99% coverage of query (869 bits)
prpD / P74840 2-methylcitrate dehydratase (EC 4.2.1.79) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
PRPD_SALTY / P74840 2-methylcitrate dehydratase; 2-MC dehydratase; Aconitate hydratase; ACN; Aconitase; EC 4.2.1.79; EC 4.2.1.3 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 2 papers)
P74840 2-methylcitrate dehydratase (EC 4.2.1.79) from Salmonella enterica (see paper)
81% identity, 100% coverage of query (828 bits)
AcnC / b0334 2-methylcitrate dehydratase (EC 4.2.1.79) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
prpD / P77243 2-methylcitrate dehydratase (EC 4.2.1.79) from Escherichia coli (strain K12) (see 5 papers)
PRPD_ECOLI / P77243 2-methylcitrate dehydratase; 2-MC dehydratase; (2S,3S)-2-methylcitrate dehydratase; Aconitate hydratase; ACN; Aconitase; EC 4.2.1.79; EC 4.2.1.3 from Escherichia coli (strain K12) (see 4 papers)
P77243 2-methylcitrate dehydratase (EC 4.2.1.79) from Escherichia coli (see 3 papers)
prpD / PDB|1SZQ 2-methylcitrate dehydratase; EC 4.2.1.79 from Escherichia coli K12 (see 4 papers)
81% identity, 100% coverage of query (828 bits)
PRPD_YARLI / Q6C354 2-methylcitrate dehydratase, mitochondrial; EC 4.2.1.79 from Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica) (see 2 papers)
65% identity, 99% coverage of query (667 bits)
MMGE_BACSU / P45859 Citrate/2-methylcitrate dehydratase; EC 4.2.1.- from Bacillus subtilis (strain 168) (see 2 papers)
P45859 2-methylcitrate dehydratase (EC 4.2.1.79) from Bacillus subtilis (see 2 papers)
61% identity, 98% coverage of query (608 bits)
PRPD_YEAST / Q12428 Probable 2-methylcitrate dehydratase; 2-MC dehydratase; (2S,3S)-2-methylcitrate dehydratase; EC 4.2.1.79 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
60% identity, 99% coverage of query (599 bits)
ORYR_ASPOR / Q2TXG4 2-methylcitrate dehydratase-like protein oryR; Oryzines biosynthesis cluster protein R; EC 4.2.1.- from Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold) (see paper)
50% identity, 99% coverage of query (449 bits)
PHII_FUNX7 / A0A348HAY4 Alkylcitrate dehydratase phiI; ACDH; Phomoidride biosynthesis cluster protein I; EC 4.2.1.- from Fungal sp. (strain ATCC 74256) (see 2 papers)
43% identity, 97% coverage of query (374 bits)
TSTI_TALSN / B8MKZ4 Alkylcitrate dehydratase phiI; ACDH; Phomoidride biosynthesis cluster protein I; EC 4.2.1.- from Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006) (Penicillium stipitatum) (see 3 papers)
39% identity, 97% coverage of query (315 bits)
Build an alignment for RR42_RS14485 and 9 homologs with ≥ 30% identity
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PRPD1_CORGL / Q8NSH9 2-methylcitrate dehydratase 1; 2-MC dehydratase; EC 4.2.1.79 from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see paper)
29% identity, 77% coverage of query (112 bits)
PRPD2_CORGL / Q8NSL3 2-methylcitrate dehydratase 2; 2-MC dehydratase; Aconitate hydratase; ACN; Aconitase; EC 4.2.1.79; EC 4.2.1.3 from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see paper)
28% identity, 77% coverage of query (95.9 bits)
PRPD_MYCTU / O06582 2-methylcitrate dehydratase; 2-MC dehydratase; Aconitate hydratase; ACN; Aconitase; EC 4.2.1.79; EC 4.2.1.3 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 3 papers)
28% identity, 84% coverage of query (89.0 bits)
PRPD_MYCTE / H8F0D6 2-methylcitrate dehydratase; 2-MC dehydratase; Aconitate hydratase; ACN; Aconitase; EC 4.2.1.79; EC 4.2.1.3 from Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman) (see paper)
28% identity, 84% coverage of query (89.0 bits)
Q2L8W4 2-methylcitrate dehydratase (EC 4.2.1.79) from Toxoplasma gondii (see paper)
22% identity, 85% coverage of query (60.1 bits)
ACOD1 / A6NK06 cis-aconitate decarboxylase (EC 4.1.1.6) from Homo sapiens (see 6 papers)
IRG1_HUMAN / A6NK06 Cis-aconitate decarboxylase; CAD; Aconitate decarboxylase; Aconitate decarboxylase 1; Cis-aconitic acid decarboxylase; Immune-responsive gene 1 protein; EC 4.1.1.6 from Homo sapiens (Human) (see 4 papers)
A6NK06 cis-aconitate decarboxylase (EC 4.1.1.6) from Homo sapiens (see paper)
25% identity, 81% coverage of query (55.5 bits)
6r6uA / A6NK06 Crystal structure of human cis-aconitate decarboxylase (see paper)
25% identity, 81% coverage of query (55.5 bits)
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