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Searching for up to 100 curated homologs for RR42_RS17795 FitnessBrowser__Cup4G11:RR42_RS17795 (277 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

5c7hA / Q92NR7 Crystal structure of aldo-keto reductase from sinorhizobium meliloti 1021 in complex with NADPH
    60% identity, 97% coverage of query (324 bits)

4pmjA Crystal structure of a putative oxidoreductase from sinorhizobium meliloti 1021 in complex with NADP
    60% identity, 97% coverage of query (324 bits)

YeaE / b1781 methylglyoxal reductase YeaE from Escherichia coli K-12 substr. MG1655 (see 4 papers)
yeaE / P76234 methylglyoxal reductase YeaE (EC 1.1.1.21) from Escherichia coli (strain K12) (see 3 papers)
    51% identity, 100% coverage of query (285 bits)

4wghA Crystal structure of aldo/keto reductase from klebsiella pneumoniae in complex with NADP and acetate at 1.8 a resolution
    51% identity, 100% coverage of query (281 bits)

6ciaA / A6T7Q7 Crystal structure of aldo-keto reductase from klebsiella pneumoniae in complex with NADPH.
    51% identity, 100% coverage of query (280 bits)

Q5JI09 alcohol dehydrogenase (EC 1.1.1.1) from Thermococcus kodakarensis (see paper)
    44% identity, 90% coverage of query (185 bits)

Q8TZM9 alcohol dehydrogenase (EC 1.1.1.1) from Pyrococcus furiosus (see 2 papers)
    43% identity, 90% coverage of query (184 bits)

6kikA / Q9X265 Crystal structure of a thermostable aldo-keto reductase tm1743 in complex with inhibitor tolrestat (see paper)
    41% identity, 92% coverage of query (176 bits)

Q9X265 carbonyl reductase (NADPH) (EC 1.1.1.184) from Thermotoga maritima (see 2 papers)
    41% identity, 92% coverage of query (176 bits)

6kiyA Crystal structure of a thermostable aldo-keto reductase tm1743 in complex with inhibitor epalrestat
    41% identity, 92% coverage of query (176 bits)

5danA Crystal structure of a novel aldo keto reductase tm1743 from thermotoga maritima in complex with NADP+
    41% identity, 92% coverage of query (176 bits)

PR / Q3L181 perakine reductase (EC 1.1.1.317) from Rauvolfia serpentina (see 2 papers)
PERR_RAUSE / Q3L181 Perakine reductase; EC 1.1.1.317 from Rauvolfia serpentina (Serpentine wood) (Ophioxylon serpentinum) (see 2 papers)
Q3L181 perakine reductase (EC 1.1.1.317) from Rauvolfia serpentina (see 3 papers)
    32% identity, 92% coverage of query (134 bits)

3v0sA / Q3L181 Crystal structure of perakine reductase, founder member of a novel akr subfamily with unique conformational changes during NADPH binding (see paper)
    33% identity, 92% coverage of query (133 bits)

A0QV10 Aldo-keto reductase MSMEG_2408/MSMEI_2347; EC 1.1.1.- from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis)
    33% identity, 93% coverage of query (132 bits)

4gieA / Q4DJ07 Crystal structure of prostaglandin f synthase from trypanosoma cruzi bound to NADP (see paper)
    30% identity, 94% coverage of query (128 bits)

Q4DJ07 prostaglandin-F synthase (EC 1.1.1.188) from Trypanosoma cruzi (see paper)
    30% identity, 94% coverage of query (128 bits)

4fziA Crystal structure of prostaglandin f synthase from trypanosoma cruzi
    30% identity, 94% coverage of query (128 bits)

A0A3P3ZE14 prostaglandin-F synthase (EC 1.1.1.188) from Leishmania braziliensis (see paper)
    32% identity, 94% coverage of query (123 bits)

F2YCN5 D-xylose reductase (EC 1.1.1.307) from Zymomonas mobilis subsp. mobilis (see paper)
    30% identity, 98% coverage of query (123 bits)

PGFS_LEIMA / P22045 9,11-endoperoxide prostaglandin H2 reductase; Prostaglandin F2-alpha synthase; EC 1.1.1.- from Leishmania major (see paper)
P22045 prostaglandin-F synthase (EC 1.1.1.188) from Leishmania major (see paper)
    32% identity, 94% coverage of query (120 bits)

4g5dA / P22045 X-ray crystal structure of prostaglandin f synthase from leishmania major friedlin bound to NADPH (see paper)
    32% identity, 94% coverage of query (120 bits)

YajO / b0419 1-deoxyxylulose-5-phosphate synthase YajO from Escherichia coli K-12 substr. MG1655 (see 7 papers)
yajO / P77735 1-deoxyxylulose-5-phosphate synthase YajO from Escherichia coli (strain K12) (see 6 papers)
YAJO_ECOLI / P77735 1-deoxyxylulose-5-phosphate synthase YajO; EC 1.1.-.- from Escherichia coli (strain K12) (see 2 papers)
P77735 1-deoxy-D-xylulose-5-phosphate synthase (EC 2.2.1.7) from Escherichia coli (see paper)
    31% identity, 87% coverage of query (120 bits)

1vbjA / Q9GV41 The crystal structure of prostaglandin f synthase from trypanosoma brucei
    30% identity, 94% coverage of query (119 bits)

PGFS_TRYBB / Q9GV41 9,11-endoperoxide prostaglandin H2 reductase; Prostaglandin F2-alpha synthase; EC 1.1.1.- from Trypanosoma brucei brucei (see paper)
    30% identity, 94% coverage of query (119 bits)

Build an alignment

Build an alignment for RR42_RS17795 and 24 homologs with ≥ 30% identity

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Change minimum %identity:

Additional hits (identity < 30%)

DkgB / b0207 methylglyoxal reductase DkgB (EC 1.1.1.91; EC 1.1.1.346) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
dkgB / P30863 methylglyoxal reductase DkgB (EC 1.1.1.21; EC 1.1.1.91; EC 1.1.1.346) from Escherichia coli (strain K12) (see 5 papers)
dkgB / MB|P30863 2,5-diketo-D-gluconic acid reductase B; EC 1.1.1.274 from Escherichia coli K12 (see 5 papers)
    29% identity, 95% coverage of query (117 bits)

GS69_BACSU / P80874 Aldo-keto reductase YhdN; AKR11B; General stress protein 69; GSP69; EC 1.1.1.- from Bacillus subtilis (strain 168) (see 3 papers)
    34% identity, 80% coverage of query (117 bits)

ALKR4_ARATH / Q93ZN2 Probable aldo-keto reductase 4; EC 1.1.1.- from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    30% identity, 94% coverage of query (114 bits)

AKR1_SOYBN / C6TBN2 Probable aldo-keto reductase 1; GmAKR1; EC 1.1.1.- from Glycine max (Soybean) (Glycine hispida) (see paper)
    29% identity, 91% coverage of query (114 bits)

akr5f1 organophosphate reductase from Klebsiella sp. F51-1-2 (see paper)
    34% identity, 95% coverage of query (114 bits)

1pz1A / P80874 Structure of NADPH-dependent family 11 aldo-keto reductase akr11b(holo) (see paper)
    33% identity, 80% coverage of query (114 bits)

3d3fA / O32210 Crystal structure of yvgn and cofactor NADPH from bacillus subtilis (see paper)
    34% identity, 99% coverage of query (114 bits)

yvgN / O32210 glyoxal/methylglyoxal reductase (EC 1.1.1.283; EC 1.1.1.91) from Bacillus subtilis (strain 168) (see 3 papers)
GR_BACSU / O32210 Glyoxal reductase; GR; Methylglyoxal reductase; EC 1.1.1.-; EC 1.1.1.283 from Bacillus subtilis (strain 168) (see paper)
    34% identity, 99% coverage of query (113 bits)

YAKC_SCHPO / Q09923 Aldo-keto reductase yakc [NADP(+)]; EC 1.1.1.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
yak3 aldose reductase YakC from Schizosaccharomyces pombe (see 3 papers)
    29% identity, 93% coverage of query (112 bits)

GCY1 putative uncharacterized protein from Candida albicans (see paper)
    30% identity, 89% coverage of query (110 bits)

5az1A Crystal structure of aldo-keto reductase (akr2e5) complexed with nadph (see paper)
    30% identity, 95% coverage of query (108 bits)

2wzmA / A0QV09 Crystal structure of a mycobacterium aldo-keto reductase in its apo and liganded form (see paper)
    29% identity, 95% coverage of query (107 bits)

Y2407_MYCS2 / A0QV09 Aldo-keto reductase MSMEG_2407/MSMEI_2346; AKR; AKR5H1; EC 1.1.1.- from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see paper)
    28% identity, 95% coverage of query (106 bits)

1pz0A / P46336 Structure of NADPH-dependent family 11 aldo-keto reductase akr11a(holo) (see paper)
    29% identity, 92% coverage of query (106 bits)

YPR1_YEAST / Q12458 Putative reductase 1; EC 1.1.1.- from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
    30% identity, 90% coverage of query (105 bits)

BN592_00768 / R7AF73 NAD(P)-dependent bile acid 3β-dehydrogenase (EC 1.1.1.391) from Eggerthella sp. CAG:298 (see 2 papers)
R7AF73 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific) (EC 1.1.1.213); 3beta-hydroxysteroid 3-dehydrogenase (EC 1.1.1.270) from Eggerthella sp. CAG:298 (see paper)
    29% identity, 96% coverage of query (105 bits)

DHB5_MOUSE / P70694 Estradiol 17 beta-dehydrogenase 5; 17-beta-HSD 5; EC 1.1.1.- from Mus musculus (Mouse) (see paper)
    29% identity, 94% coverage of query (105 bits)

GCY1_YEAST / P14065 Glycerol 2-dehydrogenase (NADP(+)); Galactose-inducible crystallin-like protein 1; EC 1.1.1.156 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 13 papers)
    29% identity, 90% coverage of query (105 bits)

IOLS_BACSU / P46336 Aldo-keto reductase IolS; AKR11A; Vegetative protein 147; VEG147; EC 1.1.1.- from Bacillus subtilis (strain 168) (see 4 papers)
    29% identity, 92% coverage of query (104 bits)

AKR1E2 / P82125 1,5-anhydro-D-fructose reductase (EC 1.1.1.263) from Sus scrofa (see paper)
AKCL2_PIG / P82125 1,5-anhydro-D-fructose reductase; AF reductase; Aldo-keto reductase family 1 member C-like protein 2; Aldo-keto reductase family 1 member CL2; Aldo-keto reductase family 1 member E2; EC 1.1.1.263 from Sus scrofa (Pig) (see paper)
    29% identity, 91% coverage of query (103 bits)

AK1C1_MACFU / Q95JH6 Aldo-keto reductase family 1 member C1; 20-alpha-hydroxysteroid dehydrogenase; 20-alpha-HSD; Dihydrodiol dehydrogenase 1; DD-1; DD1; EC 1.1.1.-; EC 1.1.1.112; EC 1.1.1.209; EC 1.1.1.210; EC 1.1.1.357; EC 1.1.1.51; EC 1.1.1.53; EC 1.1.1.62; EC 1.3.1.20; EC 1.1.1.149 from Macaca fuscata fuscata (Japanese macaque) (see paper)
    28% identity, 94% coverage of query (102 bits)

3wbwA / Q5FT75 Crystal structure of gox0644 in complex with NADPH
    28% identity, 94% coverage of query (102 bits)

Q5FT75 carbonyl reductase (NADPH) (EC 1.1.1.184) from Gluconobacter oxydans (see paper)
    28% identity, 94% coverage of query (102 bits)

AK1C1_MACFA / Q95JH7 Aldo-keto reductase family 1 member C1; 20-alpha-hydroxysteroid dehydrogenase; 20-alpha-HSD; Dihydrodiol dehydrogenase 1; DD-1; DD1; EC 1.1.1.-; EC 1.1.1.112; EC 1.1.1.209; EC 1.1.1.210; EC 1.1.1.357; EC 1.1.1.51; EC 1.1.1.53; EC 1.1.1.62; EC 1.3.1.20; EC 1.1.1.149 from Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) (see paper)
    27% identity, 94% coverage of query (101 bits)

eryBII / A4F7P4 dTDP-(2R,6S)-6-hydroxy-2-methyl-3-oxo-3,6-dihydro-2H-pyran-4-olate 3-ketoreductase (dTDP-4-dehydro-2,6-dideoxy-α-D-allose-forming) from Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 / NRRL 2338) (see 2 papers)
    31% identity, 91% coverage of query (101 bits)

AKR1C1 / Q04828 aldo-keto reductase family 1 member C1 (EC 1.1.1.149; EC 1.1.1.213; EC 1.1.1.112; EC 1.3.1.20) from Homo sapiens (see 13 papers)
AK1C1_HUMAN / Q04828 Aldo-keto reductase family 1 member C1; 20-alpha-hydroxysteroid dehydrogenase; 20-alpha-HSD; Chlordecone reductase homolog HAKRC; Dihydrodiol dehydrogenase 1; DD1; High-affinity hepatic bile acid-binding protein; HBAB; EC 1.1.1.-; EC 1.1.1.112; EC 1.1.1.209; EC 1.1.1.210; EC 1.1.1.357; EC 1.1.1.51; EC 1.1.1.53; EC 1.1.1.62; EC 1.3.1.20; EC 1.1.1.149 from Homo sapiens (Human) (see 8 papers)
Q04828 20alpha-hydroxysteroid dehydrogenase (EC 1.1.1.149); 3beta-hydroxysteroid 3-dehydrogenase (EC 1.1.1.270); 3alpha-hydroxysteroid 3-dehydrogenase (EC 1.1.1.357); 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific) (EC 1.1.1.50); trans-1,2-dihydrobenzene-1,2-diol dehydrogenase (EC 1.3.1.20) from Homo sapiens (see 13 papers)
    27% identity, 94% coverage of query (100 bits)

AKR1C2 / P52895 3α hydroxysteroid dehydrogenase III (EC 1.1.1.52; EC 1.1.1.395; EC 1.1.1.213; EC 1.1.1.357) from Homo sapiens (see 12 papers)
AK1C2_HUMAN / P52895 Aldo-keto reductase family 1 member C2; 3-alpha-HSD3; Chlordecone reductase homolog HAKRD; Dihydrodiol dehydrogenase 2; DD-2; DD2; Dihydrodiol dehydrogenase/bile acid-binding protein; DD/BABP; Type III 3-alpha-hydroxysteroid dehydrogenase; EC 1.-.-.-; EC 1.1.1.112; EC 1.1.1.209; EC 1.1.1.53; EC 1.1.1.62; EC 1.3.1.20; EC 1.1.1.357 from Homo sapiens (Human) (see 9 papers)
P52895 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific) (EC 1.1.1.213); 3alpha-hydroxysteroid 3-dehydrogenase (EC 1.1.1.357); 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific) (EC 1.1.1.50); trans-1,2-dihydrobenzene-1,2-diol dehydrogenase (EC 1.3.1.20) from Homo sapiens (see 9 papers)
    27% identity, 94% coverage of query (100 bits)

4l1wA / P52895 Crystal structuer of human 3-alpha hydroxysteroid dehydrogenase type 3 in complex with NADP+ and progesterone (see paper)
    28% identity, 94% coverage of query (100 bits)

Y2971_MYCTU / P9WQA5 Aldo-keto reductase Rv2971; AKR; EC 1.1.1.- from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 3 papers)
    29% identity, 94% coverage of query (100 bits)

1a80A / P06632 Native 2,5-diketo-d-gluconic acid reductase a from corynbacterium sp. Complexed with NADPH (see paper)
    30% identity, 97% coverage of query (100 bits)

6ijxA Crystal structure of akr1c1 complexed with meclofenamic acid
    27% identity, 94% coverage of query (100 bits)

6a7aA Akr1c1 complexed with new inhibitor with novel scaffold
    27% identity, 94% coverage of query (100 bits)

4yvpA Crystal structure of akr1c1 complexed with glibenclamide
    27% identity, 94% coverage of query (100 bits)

3ntyA Crystal structure of akr1c1 in complex with NADP and 5-phenyl,3- chlorosalicylic acid
    27% identity, 94% coverage of query (100 bits)

3c3uA Crystal structure of akr1c1 in complex with NADP and 3,5- dichlorosalicylic acid
    27% identity, 94% coverage of query (100 bits)

3gugA Crystal structure of akr1c1 l308v mutant in complex with NADP and 3,5- dichlorosalicylic acid
    27% identity, 94% coverage of query (100 bits)

1ihiA Crystal structure of human type iii 3-alpha-hydroxysteroid dehydrogenase/bile acid binding protein (akr1c2) complexed with NADP+ and ursodeoxycholate
    28% identity, 94% coverage of query (100 bits)

4jtrB Akr1c2 complex with ibuprofen
    28% identity, 94% coverage of query (100 bits)

4xo7A Crystal structure of human 3-alpha hydroxysteroid dehydrogenase type 3 in complex with NADP+, 5alpha-androstan-3,17-dione and (3beta, 5alpha)-3-hydroxyandrostan-17-one
    28% identity, 94% coverage of query (100 bits)

2hdjA Crystal structure of human type 3 3alpha-hydroxysteroid dehydrogenase in complex with NADP(h)
    28% identity, 94% coverage of query (100 bits)

4xo6B Crystal structure of human 3-alpha hydroxysteroid dehydrogenase type 3 in complex with NADP+, 5alpha-androstan-3,17-dione and (3beta, 5alpha)-3-hydroxyandrostan-17-one
    28% identity, 94% coverage of query (100 bits)

4xo6A Crystal structure of human 3-alpha hydroxysteroid dehydrogenase type 3 in complex with NADP+, 5alpha-androstan-3,17-dione and (3beta, 5alpha)-3-hydroxyandrostan-17-one
    28% identity, 94% coverage of query (100 bits)

1xjbA Crystal structure of human type 3 3alpha-hydroxysteroid dehydrogenase in complex with NADP(h), citrate and acetate molecules
    28% identity, 94% coverage of query (100 bits)

1j96A Human 3alpha-hsd type 3 in ternary complex with NADP and testosterone
    28% identity, 94% coverage of query (100 bits)

4jtrA Akr1c2 complex with ibuprofen
    27% identity, 94% coverage of query (100 bits)

4jtqA Akr1c2 complex with flurbiprofen
    27% identity, 94% coverage of query (100 bits)

4jqaA Akr1c2 complex with mefenamic acid
    27% identity, 94% coverage of query (100 bits)

4jq4A Akr1c2 complex with indomethacin
    27% identity, 94% coverage of query (100 bits)

4jq3A Akr1c2 complex with zomepirac
    27% identity, 94% coverage of query (100 bits)

4jq2A Akr1c2 complex with sulindac
    27% identity, 94% coverage of query (100 bits)

4jq1A Akr1c2 complex with naproxen
    27% identity, 94% coverage of query (100 bits)

dkgA / P06632 2,5-diketo-D-gluconate reductase A monomer (EC 1.1.1.346) from Corynebacterium sp. (strain ATCC 31090) (see 4 papers)
DKGA_CORSC / P06632 2,5-diketo-D-gluconic acid reductase A; 2,5-DKG reductase A; 2,5-DKGR A; 25DKGR-A; AKR5C; EC 1.1.1.346 from Corynebacterium sp. (strain ATCC 31090) (see 2 papers)
P06632 2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming) (EC 1.1.1.346) from Corynebacterium sp. (see paper)
    30% identity, 97% coverage of query (99.8 bits)

1vp5A / Q9X0A2 Crystal structure of 2,5-diketo-d-gluconic acid reductase (tm1009) from thermotoga maritima at 2.40 a resolution
    30% identity, 93% coverage of query (99.8 bits)

D0VDT4 20alpha-hydroxysteroid dehydrogenase (EC 1.1.1.149) from Bos taurus (see paper)
    26% identity, 94% coverage of query (99.8 bits)

5uxfA Crystal structure of mouse recon (akr1c13) in complex with cyclic di- amp
    27% identity, 94% coverage of query (99.0 bits)

3ufyA Akr1c3 complex with r-naproxen
    28% identity, 94% coverage of query (99.0 bits)

3r94A Akr1c3 complex with flurbiprofen
    28% identity, 94% coverage of query (99.0 bits)

3r8hA Akr1c3 complex with zomepirac
    28% identity, 94% coverage of query (99.0 bits)

3r8gA Akr1c3 complex with ibuprofen
    28% identity, 94% coverage of query (99.0 bits)

3r7mA Akr1c3 complex with sulindac
    28% identity, 94% coverage of query (99.0 bits)

3r6iA Akr1c3 complex with meclofenamic acid
    28% identity, 94% coverage of query (99.0 bits)

Y2996_MYCBO / Q7TXI6 Aldo-keto reductase BQ2027_MB2996; EC 1.1.1.- from Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) (see paper)
    29% identity, 94% coverage of query (98.6 bits)

3r58A Akr1c3 complex with naproxen
    28% identity, 94% coverage of query (98.6 bits)

4falA Crystal structure of human 17beta-hydroxysteroid dehydrogenase type 5 in complex with 3-((3,4-dihydroisoquinolin-2(1h)-yl)sulfonyl)-n- methylbenzamide (80)
    28% identity, 94% coverage of query (98.6 bits)

4fa3A Crystal structure of human 17beta-hydroxysteroid dehydrogenase type 5 in complex with (r)-1-(naphthalen-2-ylsulfonyl)piperidine-3- carboxylic acid (86)
    28% identity, 94% coverage of query (98.6 bits)

4hmnA Crystal structure of human 17beta-hydroxysteroid dehydrogenase type 5 in complex with (4-(4-chlorophenyl)piperazin-1-yl)(morpholino) methanone (24)
    28% identity, 94% coverage of query (98.2 bits)

4h7cA Crystal structure of human 17beta-hydroxysteroid dehydrogenase type 5 in complex with 1-{4-[(2-methyl-1-piperidinyl)sulfonyl]phenyl}-2- pyrrolidinone
    28% identity, 94% coverage of query (98.2 bits)

E3W861 carbonyl reductase (NADPH) (EC 1.1.1.184) from Bacillus sp. (in: Bacteria) (see paper)
3b3dA / O34678 B.Subtilis ytbe (see paper)
    32% identity, 94% coverage of query (97.8 bits)

YdjG / b1771 NADH-dependent methylglyoxal reductase from Escherichia coli K-12 substr. MG1655 (see 5 papers)
ydjG / P77256 NADH-dependent methylglyoxal reductase from Escherichia coli (strain K12) (see 4 papers)
AKRMG_ECOLI / P77256 NADH-specific methylglyoxal reductase; AKR11B2; EC 1.1.1.- from Escherichia coli (strain K12) (see 3 papers)
ydjG / RF|NP_416285 uncharacterized oxidoreductase ydjG from Escherichia coli K12 (see paper)
    28% identity, 92% coverage of query (97.8 bits)

2ipjA Crystal structure of h3alpha-hydroxysteroid dehydrogenase type 3 mutant y24a in complex with NADP+ and epi-testosterone
    28% identity, 94% coverage of query (97.8 bits)

7x3oA Crystal structure of aldo-keto reductase 1c3 complexed with compound s07054
    28% identity, 94% coverage of query (97.8 bits)

3cv6A / Q91WR5 The crystal structure of mouse 17-alpha hydroxysteroid dehydrogenase gg225.226pp mutant in complex with inhibitor and cofactor NADP+. (see paper)
    27% identity, 94% coverage of query (97.4 bits)

AK1CL_MOUSE / Q91WR5 Aldo-keto reductase family 1 member C21; 17-alpha-hydroxysteroid dehydrogenase; 17-alpha-HSD; 3(or 17)-alpha-hydroxysteroid dehydrogenase; 3-alpha-hydroxysteroid dehydrogenase; Dihydrodiol dehydrogenase type 1; DD1; Dihydrodiol dehydrogenase type 3; DD3; EC 1.1.1.-; EC 1.1.1.209 from Mus musculus (Mouse) (see 7 papers)
Q91WR5 estradiol 17alpha-dehydrogenase (EC 1.1.1.148); 3(or 17)alpha-hydroxysteroid dehydrogenase (EC 1.1.1.209); 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific) (EC 1.1.1.50) from Mus musculus (see 5 papers)
    27% identity, 94% coverage of query (97.1 bits)

4wdxA 17beta-hsd5 in complex with [4-(2-hydroxyethyl)piperidin-1-yl](5- methyl-1h-indol-2-yl)methanone
    28% identity, 94% coverage of query (97.1 bits)

2ipfA Crystal structure of 17alpha-hydroxysteroid dehydrogenase in complex with NADP+ and epi-testosterone
    27% identity, 94% coverage of query (97.1 bits)

2he5A Crystal structure of 17alpha-hydroxysteroid dehydrogenase in binary complex with NADP(h) in an open conformation
    27% identity, 94% coverage of query (97.1 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory