Searching for up to 100 curated homologs for RR42_RS18515 FitnessBrowser__Cup4G11:RR42_RS18515 (269 a.a.)

Found high-coverage hits (≥70%) to 22 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

Q3MFY8 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Trichormus variabilis (see paper)
    34% identity, 99% coverage of query (134 bits)

dapB / P9WP23 dihydropicolinate reductase subunit (EC 1.17.1.8) from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
DAPB_MYCTU / P9WP23 4-hydroxy-tetrahydrodipicolinate reductase; HTPA reductase; EC 1.17.1.8 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 3 papers)
P9WP23 4-hydroxy-tetrahydrodipicolinate reductase (EC 1.17.1.8) from Mycobacterium tuberculosis (see 3 papers)
    34% identity, 98% coverage of query (131 bits)

1yl5A / P9WP23 Crystal structure of mycobacterium tuberculosis dihydrodipicolinate reductase (rv2773c) (crystal form a) (see paper)
    34% identity, 97% coverage of query (130 bits)

5ugvA Dapb from mycobacterium tuberculosis
    34% identity, 98% coverage of query (130 bits)

5tjzA Structure of 4-hydroxytetrahydrodipicolinate reductase from mycobacterium tuberculosis with NADPH and 2,6 pyridine dicarboxylic acid
    34% identity, 98% coverage of query (130 bits)

1p9lA Structure of m. Tuberculosis dihydrodipicolinate reductase in complex with nadh and 2,6 pdc
    34% identity, 98% coverage of query (130 bits)

1c3vA Dihydrodipicolinate reductase from mycobacterium tuberculosis complexed with NADPH and pdc
    34% identity, 98% coverage of query (130 bits)

dapB / P42976 dihydrodipicolinate reductase subunit (EC 1.17.1.8) from Bacillus subtilis (strain 168) (see 3 papers)
    32% identity, 99% coverage of query (129 bits)

5z2eA / A0A3B6UER2 Dipicolinate bound dihydrodipicolinate reductase from paenisporosarcina sp. Tg-14 (see paper)
    32% identity, 97% coverage of query (126 bits)

5z2fA NADPH/pda bound dihydrodipicolinate reductase from paenisporosarcina sp. Tg-14
    32% identity, 97% coverage of query (126 bits)

5wolA / P24703 Crystal structure of dihydrodipicolinate reductase dapb from coxiella burnetii
    30% identity, 97% coverage of query (115 bits)

5eerA / P40110 Crystal structure of dapb from corynebacterium glutamicum (see paper)
    31% identity, 97% coverage of query (103 bits)

dapB / P40110 dihydropicolinate reductase subunit (EC 1.17.1.8) from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see 2 papers)
P40110 4-hydroxy-tetrahydrodipicolinate reductase (EC 1.17.1.8) from Corynebacterium glutamicum (see paper)
    31% identity, 97% coverage of query (103 bits)

5eesA Crystal structure of dapb in complex with NADP+ from corynebacterium glutamicum
    31% identity, 97% coverage of query (103 bits)

dapB / CAA79712.1 dihydrodipicolinate reductase from Corynebacterium glutamicum (see paper)
    31% identity, 97% coverage of query (102 bits)

Build an alignment

Build an alignment for RR42_RS18515 and 15 homologs with ≥ 30% identity

Or download the sequences

Additional hits (identity < 30%)

DAPB3_ARATH / Q9FJ82 Dihydrodipicolinate reductase-like protein CRR1, chloroplastic; 4-hydroxy-tetrahydrodipicolinate reductase 3; HTPA reductase 3; Protein CHLORORESPIRATORY REDUCTION 1 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
    27% identity, 98% coverage of query (80.1 bits)

Q9K1F1 4-hydroxy-tetrahydrodipicolinate reductase (EC 1.17.1.8) from Neisseria meningitidis (see paper)
    26% identity, 94% coverage of query (68.2 bits)

DAPB_THEMA / Q9X1K8 4-hydroxy-tetrahydrodipicolinate reductase; HTPA reductase; EC 1.17.1.8 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
    25% identity, 72% coverage of query (50.8 bits)

1vm6B / Q9X1K8 Crystal structure of dihydrodipicolinate reductase (tm1520) from thermotoga maritima at 2.27 a resolution
    25% identity, 72% coverage of query (50.1 bits)

Q6G2G3 4-hydroxy-tetrahydrodipicolinate reductase (EC 1.17.1.8) from Bartonella henselae (see paper)
    27% identity, 91% coverage of query (45.8 bits)

3ijpB / Q6G2G3 Crystal structure of dihydrodipicolinate reductase from bartonella henselae at 2.0a resolution (see paper)
    27% identity, 91% coverage of query (45.8 bits)

3ijpA Crystal structure of dihydrodipicolinate reductase from bartonella henselae at 2.0a resolution
    27% identity, 91% coverage of query (45.8 bits)

Or start over