Searching for up to 100 curated homologs for RR42_RS20415 RR42_RS20415 ABC transporter substrate-binding protein (377 a.a.)
Found high-coverage hits (≥70%) to 18 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
TC 2.A.56.3.4 / D5ALT6 TRAP dicarboxylate transporter, DctP-2 subunit, component of The 2-ketomonocarboxylate transporter (presented in order of affinity - 2-oxovalerate [highest affinity, KD=0.1 μM], 2-oxoisovalerate, 2-oxobutyrate, 2-oxoisocaproate, 2-oxo-3-methylvalerate, pyruvate [lowest affinity, KD=3 μM]) from Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003) (see paper)
60% identity, 87% coverage of query (414 bits)
2hzlB / Q3J1R2 Crystal structures of a sodium-alpha-keto acid binding subunit from a trap transporter in its closed forms (see paper)
59% identity, 86% coverage of query (414 bits)
TAKP_CERS4 / Q3J1R2 Alpha-keto acid-binding periplasmic protein TakP; Extracytoplasmic solute receptor protein TakP; TRAP transporter alpha-keto acid-binding subunit P; TRAP-T family sorbitol/mannitol transporter, periplasmic binding protein, SmoM from Cereibacter sphaeroides (strain ATCC 17023 / DSM 158 / JCM 6121 / CCUG 31486 / LMG 2827 / NBRC 12203 / NCIMB 8253 / ATH 2.4.1.) (Rhodobacter sphaeroides) (see paper)
59% identity, 86% coverage of query (412 bits)
4yicA / A0A0J9X284 Crystal structure of a trap transporter solute binding protein (ipr025997) from bordetella bronchiseptica rb50 (bb0280, target efi- 500035) with bound picolinic acid
55% identity, 88% coverage of query (392 bits)
TMBP_NOSS1 / Q8YSQ6 Monocarboxylate 2-oxoacid-binding periplasmic protein all3028; Extracellular solute-binding protein; Extracytoplasmic solute receptor protein all3028; TRAP transporter monocarboxylate 2-oxoacid-binding subunit P from Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576) (see paper)
TC 2.A.56.3.3 / Q8YSQ6 Extracellular solute-binding protein, component of The 2-oxo monocarboxylate transporter (Pernil et al., 2010). Transports pyruvate which is inhibited by various 2-ketoacids from Nostoc sp. (strain PCC 7120 / UTEX 2576) (see paper)
48% identity, 100% coverage of query (367 bits)
7ug8B / Q0I6F8 Crystal structure of a solute receptor from synechococcus cc9311 in complex with alpha-ketovaleric and calcium
47% identity, 87% coverage of query (326 bits)
5cm6A Crystal structure of a trap periplasmic solute binding protein from pseudoalteromonas atlantica t6c(patl_2292, target efi-510180) with bound sodium and pyruvate
41% identity, 85% coverage of query (246 bits)
4petA / Q48AL6 Crystal structure of a trap periplasmic solute binding protein from colwellia psychrerythraea (cps_0129, target efi-510097) with bound calcium and pyruvate (see paper)
38% identity, 85% coverage of query (240 bits)
Build an alignment for RR42_RS20415 and 8 homologs with ≥ 30% identity
Or download the sequences
TLBP_THET8 / Q5SK82 Lactate-binding periplasmic protein TTHA0766; ABC transporter, solute-binding protein; Extracytoplasmic solute receptor protein TTHA0766; TRAP transporter lactate-binding subunit P from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see paper)
26% identity, 81% coverage of query (99.8 bits)
2zzvA / Q5SK82 Crystal structure of a periplasmic substrate binding protein in complex with calcium and lactate (see paper)
27% identity, 71% coverage of query (95.1 bits)
2zzwA Crystal structure of a periplasmic substrate binding protein in complex with zinc and lactate
27% identity, 71% coverage of query (95.1 bits)
TC 2.A.56.3.2 / Q9RBR1 FcbT1, component of Tripartite 4-chlorobenzoate symporter (also binds and may transport 4-bromo-, 4-iodo-, and 4-fluorobenzoate and with a lower affinity, 3-chlorobenzoate, 2-chlorobenzoate, 4-hydroxybenzoate, 3-hydroxybenzoate, and benzoate) (see paper)
24% identity, 72% coverage of query (57.0 bits)
4nhbB / B8J100 Crystal structure of a trap periplasmic solute binding protein from desulfovibrio desulfuricans (ddes_1525), target efi-510107, with bound sn-glycerol-3-phosphate (see paper)
22% identity, 78% coverage of query (52.8 bits)
4p8bA / Q0KC03 Crystal structure of a trap periplasmic solute binding protein from ralstonia eutropha h16 (h16_a1328), target efi-510189, with bound (s)-2-hydroxy-2-methyl-3-oxobutanoate ((s)-2-acetolactate) (see paper)
22% identity, 76% coverage of query (50.8 bits)
4x04A / A8AR30 Crystal structure of a trap periplasmic solute binding protein from citrobacter koseri (cko_04899, target efi-510094) with bound d- glucuronate
23% identity, 74% coverage of query (47.4 bits)
DCTP1_POLSJ / Q128M1 Solute-binding protein Bpro_3107 from Polaromonas sp. (strain JS666 / ATCC BAA-500) (see paper)
24% identity, 75% coverage of query (45.4 bits)
4mhfA Crystal structure of a trap periplasmic solute binding protein from polaromonas sp. Js666 (bpro_3107), target efi-510173, with bound alpha/beta d-glucuronate, space group p21
24% identity, 75% coverage of query (45.4 bits)
4mijA / Q128M1 Crystal structure of a trap periplasmic solute binding protein from polaromonas sp. Js666 (bpro_3107), target efi-510173, with bound alpha/beta d-galacturonate, space group p21 (see paper)
24% identity, 75% coverage of query (45.4 bits)
Or start over
Lawrence Berkeley National Laboratory