Sites on a Tree

 

Searching for up to 100 curated homologs for RR42_RS22775 FitnessBrowser__Cup4G11:RR42_RS22775 (208 a.a.)

Found high-coverage hits (≥70%) to 17 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

LEUD_RHIJ3 / Q1MA52 3-isopropylmalate dehydratase small subunit; Alpha-IPM isomerase; IPMI; Isopropylmalate isomerase; EC 4.2.1.33 from Rhizobium johnstonii (strain DSM 114642 / LMG 32736 / 3841) (Rhizobium leguminosarum bv. viciae) (see paper)
    47% identity, 96% coverage of query (197 bits)

O14289 3-isopropylmalate dehydratase; Alpha-IPM isomerase; IPMI; Isopropylmalate isomerase; EC 4.2.1.33 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
    47% identity, 98% coverage of query (178 bits)

leuD / Q8F4E5 isopropylmalate isomerase small subunit (EC 4.2.1.35) from Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601) (see paper)
    43% identity, 97% coverage of query (176 bits)

leuD / BAC65258.1 3-isopropylmalate dehydratase small subunit from Burkholderia multivorans (see paper)
    42% identity, 95% coverage of query (170 bits)

AN5886 alpha isopropylmalate isomerase (Eurofung) from Emericella nidulans (see paper)
    44% identity, 94% coverage of query (167 bits)

hbzJ / Q0QFQ6 maleate hydratase small subunit (EC 4.2.1.31) from Pseudomonas alcaligenes (see 3 papers)
Q0QFQ6 maleate hydratase (subunit 1/2) (EC 4.2.1.31) from Pseudomonas alcaligenes (see paper)
    41% identity, 97% coverage of query (164 bits)

LEUD1_SALTY / P04787 3-isopropylmalate dehydratase small subunit 1; Alpha-IPM isomerase 1; IPMI 1; Isopropylmalate isomerase 1; EC 4.2.1.33 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
    42% identity, 91% coverage of query (145 bits)

LeuD / b0071 3-isopropylmalate dehydratase subunit LeuD (EC 4.2.1.33) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
leuD / P30126 3-isopropylmalate dehydratase subunit LeuD (EC 4.2.1.33) from Escherichia coli (strain K12) (see 4 papers)
    42% identity, 90% coverage of query (141 bits)

LEUC_YEAST / P07264 3-isopropylmalate dehydratase; Alpha-IPM isomerase; IPMI; Isopropylmalate isomerase; EC 4.2.1.33 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
    40% identity, 94% coverage of query (141 bits)

leu1 / CAB99455.1 3-isopropylmalate dehydratase, partial from Yarrowia lipolytica (see paper)
    42% identity, 82% coverage of query (122 bits)

LEUD_CORGL / Q8NQV7 3-isopropylmalate dehydratase small subunit; Alpha-IPM isomerase; IPMI; Isopropylmalate isomerase; EC 4.2.1.33 from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / BCRC 11384 / CCUG 27702 / LMG 3730 / NBRC 12168 / NCIMB 10025 / NRRL B-2784 / 534) (see paper)
    37% identity, 87% coverage of query (109 bits)

LEUD_MYCBO / P65278 3-isopropylmalate dehydratase small subunit; Alpha-IPM isomerase; IPMI; Isopropylmalate isomerase; EC 4.2.1.33 from Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) (see paper)
P9WK95 3-isopropylmalate dehydratase (EC 4.2.1.33) from Mycobacterium tuberculosis (see paper)
    37% identity, 92% coverage of query (100 bits)

P9WK95 3-isopropylmalate dehydratase small subunit; Alpha-IPM isomerase; IPMI; Isopropylmalate isomerase; EC 4.2.1.33 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
    37% identity, 92% coverage of query (100 bits)

ACON3_ASPFU / Q4WBR0 Putative aconitate hydratase; Aconitase 3; EC 4.2.1.- from Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata) (see paper)
    32% identity, 81% coverage of query (78.2 bits)

DVU2983 3-isopropylmalate dehydratase / (R)-citramalate isomerase, small subunit LeuD (EC 4.2.1.33; EC 4.2.1.35) from Desulfovibrio vulgaris Hildenborough JW710
    33% identity, 73% coverage of query (66.6 bits)

LEUD2_ARATH / Q9LYT7 3-isopropylmalate dehydratase small subunit 3; 2-(omega-methylthio)alkylmalate dehydratase small subunit 3; AtLEUD2; Isopropylmalate isomerase 1; Isopropylmalate isomerase small subunit 3; IPMI SSU3; Methylthioalkylmalate isomerase small subunit; MAM-IS; EC 4.2.1.33; EC 4.2.1.170 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
Q9LYT7 2-(omega-methylthio)alkylmalate dehydratase (subunit 1/2) (EC 4.2.1.170); 3-isopropylmalate dehydratase (EC 4.2.1.33) from Arabidopsis thaliana (see paper)
    33% identity, 78% coverage of query (64.3 bits)

AMT8_ALTAL / C9K7B9 Aconitase AMT8; AM-toxin biosynthesis protein 8; EC 4.2.1.- from Alternaria alternata (Alternaria rot fungus) (Torula alternata) (see 3 papers)
    36% identity, 70% coverage of query (63.9 bits)

Build an alignment

Build an alignment for RR42_RS22775 and 17 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

No additional hits (below 30% identity) were found

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory