Searching for up to 100 curated homologs for RR42_RS22885 FitnessBrowser__Cup4G11:RR42_RS22885 (288 a.a.)
Found high-coverage hits (≥70%) to 48 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
TC 3.A.1.1.41 / G4FGN6 ABC-type transporter, integral membrane subunit, component of Trehalose porter. Also binds sucrose (Boucher and Noll, 2011). Induced by glucose and trehalose. Directly regulated by trehalose-responsive regulator TreR from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
32% identity, 89% coverage of query (141 bits)
smoH / Q7CS31 ABC-type 3-(6-sulfo-α-D-quinovosyl)-sn-glycerol transporter permease subunit from Agrobacterium fabrum (strain C58 / ATCC 33970) (see paper)
36% identity, 89% coverage of query (137 bits)
Build an alignment for RR42_RS22885 and 2 homologs with ≥ 30% identity
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TC 3.A.1.1.44 / Q9KZ08 Putative maltose permease, component of MalEFG (K unknown), involved in maltose and maltodextrin uptake from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
29% identity, 97% coverage of query (135 bits)
YcjP / b1312 putative ABC transporter membrane subunit YcjP from Escherichia coli K-12 substr. MG1655 (see 2 papers)
TC 3.A.1.1.46 / P77716 Inner membrane ABC transporter permease protein YcjP, component of Probable glucoside uptake porter, YcjNOPV from Escherichia coli (strain K12)
32% identity, 96% coverage of query (135 bits)
Pf1N1B4_5114 sucrose ABC transporter, permease component 2 from Pseudomonas fluorescens FW300-N1B4
32% identity, 93% coverage of query (132 bits)
Dshi_0549 ABC transporter for Xylitol, permease component 2 from Dinoroseobacter shibae DFL-12
30% identity, 94% coverage of query (129 bits)
TC 3.A.1.1.25 / Q72H66 Maltose transport system permease protein malG aka TT_C1629, component of The trehalose/maltose/sucrose/palatinose porter (TTC1627-9) plus MalK1 (ABC protein, shared with 3.A.1.1.24) (Silva et al. 2005; Chevance et al., 2006). The receptor (TTC1627) binds disaccharide alpha-glycosides, namely trehalose (alpha-1,1), sucrose (alpha-1,2), maltose (alpha-1,4), palatinose (alpha-1,6) and glucose from Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) (see paper)
33% identity, 88% coverage of query (123 bits)
TC 3.A.1.1.12 / Q9AI66 PalG, component of Palatinose (isomaltulose; 6-O-α-D-glucopyranosyl-D-fructose) uptake porter from Erwinia rhapontici (see paper)
29% identity, 89% coverage of query (121 bits)
MALG_THELN / Q7LYX6 Trehalose/maltose transport system permease protein MalG from Thermococcus litoralis (strain ATCC 51850 / DSM 5473 / JCM 8560 / NS-C) (see 3 papers)
TC 3.A.1.1.7 / O51925 MalG aka PF1741, component of Maltose/trehalose porter (see paper)
29% identity, 89% coverage of query (118 bits)
PS417_12705 ABC transporter for D-Mannitol and D-Sorbitol, permease component 1 from Pseudomonas simiae WCS417
28% identity, 89% coverage of query (117 bits)
SM_b20327 ABC transporter for D-trehalose/D-maltose/sucrose, permease component 2 (ThuG) from Sinorhizobium meliloti 1021
TC 3.A.1.1.17 / Q9R9Q5 ThuG aka RB0313 aka SMB20327, component of Trehalose/maltose/sucrose porter (trehalose inducible) from Rhizobium meliloti (Sinorhizobium meliloti) (see 3 papers)
34% identity, 94% coverage of query (117 bits)
DASC_STRCO / Q9K489 Diacetylchitobiose uptake system permease protein DasC from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) (see paper)
28% identity, 95% coverage of query (117 bits)
Pf6N2E2_1961 ABC transporter for D-sorbitol, permease component 2 from Pseudomonas fluorescens FW300-N2E2
28% identity, 89% coverage of query (117 bits)
TC 3.A.1.1.49 / O30493 MtlG, component of The polyol (mannitol, glucitol (sorbitol), arabitol (arabinitol; lyxitol)) uptake porter, MtlEFGK from Pseudomonas fluorescens
27% identity, 89% coverage of query (117 bits)
AO356_00015 ABC transporter for D-Sorbitol, permease component 1 from Pseudomonas fluorescens FW300-N2C3
28% identity, 89% coverage of query (117 bits)
mtlG / Q4KC55 polyol ABC-type transporter permease component MtlG from Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5) (see paper)
28% identity, 89% coverage of query (115 bits)
BPHYT_RS16105 ABC transporter for D-Sorbitol, permease component 1 from Burkholderia phytofirmans PsJN
29% identity, 89% coverage of query (112 bits)
TC 3.A.1.1.33 / Q8KN17 Putative sugar transporter integral membrane protein, component of The N,N'-diacetylchitobiose uptake transporter, DasABC/MsiK (MsiK energizes several ABC transporters (see 3.A.1.1.23)) from Streptomyces sp. 139 (see 2 papers)
29% identity, 89% coverage of query (112 bits)
sugB / P9WG01 ABC-type trehalose transporter integral membrane protein from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
SUGB_MYCTU / P9WG01 Trehalose transport system permease protein SugB from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
TC 3.A.1.1.31 / O50453 PROBABLE SUGAR-TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER SUGB, component of The trehalose-recycling ABC transporter, LpqY-SugA-SugB-SugC (essential for virulence) from Mycobacterium tuberculosis (see 3 papers)
30% identity, 90% coverage of query (107 bits)
TC 3.A.1.1.26 / O06991 MalG aka yvdI, component of The maltose porter, MdxEFG and MsmX from Bacillus subtilis (see 2 papers)
29% identity, 82% coverage of query (107 bits)
Ac3H11_794 ABC transporter for Glycerol, permease component 2 from Acidovorax sp. GW101-3H11
28% identity, 89% coverage of query (106 bits)
SM_b21105 ABC transporter for L-Fucose, permease component 2 from Sinorhizobium meliloti 1021
28% identity, 100% coverage of query (105 bits)
HSERO_RS17010 ABC transporter for D-sorbitol/xylitol, permease component 2 from Herbaspirillum seropedicae SmR1
30% identity, 89% coverage of query (105 bits)
GANQ_BACSU / O07011 Galactooligosaccharides transport system permease protein GanQ from Bacillus subtilis (strain 168) (see 2 papers)
TC 3.A.1.1.2 / O07011 Putative arabinogalactan oligomer transport system permease protein ganQ, component of The galactooligosaccharide (transports the di, tri and tetrasaccharides) uptake porter GanOPQ (GanSPQ; MalEFG) functioning with the energizing ATPase MsmX (see 3.A.1.1.26) from Bacillus subtilis (see 2 papers)
29% identity, 92% coverage of query (104 bits)
TC 3.A.1.1.27 / Q8DT26 MalG, component of Maltose/Maltotriose/maltodextrin (up to 7 glucose units) transporters MalXFGK (MsmK (3.A.1.1.28) can probably substitute for MalK; Webb et al., 2008) from Streptococcus mutans (see paper)
30% identity, 89% coverage of query (103 bits)
Q9X2F5 ABC-type maltose transporter (subunit 1/2) (EC 7.5.2.1) from Thermotoga maritima (see paper)
TC 3.A.1.1.22 / Q9X2F5 MalG2; aka Maltose ABC transporter, permease protein, component of The maltose, maltotriose, mannotetraose (MalE1)/maltose, maltotriose, trehalose (MalE2) porter (Nanavati et al., 2005). For MalG1 (823aas) and MalG2 (833aas), the C-terminal transmembrane domain with 6 putative TMSs is preceded by a single N-terminal TMS and a large (600 residue) hydrophilic region showing sequence similarity to MLP1 and 2 (9.A.14; e-12 & e-7) as well as other proteins from Thermotoga maritima (see paper)
33% identity, 73% coverage of query (97.1 bits)
TC 3.A.1.1.18 / Q8RJU8 NgcG, component of N-Acetylglucosamine/N,N'-diacetyl chitobiose porter (NgcK (C) not identified) from Streptomyces olivaceoviridis (Streptomyces corchorusii) (see paper)
27% identity, 94% coverage of query (96.3 bits)
TC 3.A.1.1.38 / Q9WYQ1 Sugar ABC transporter, permease protein, component of Inositol phosphate porter (Rodionova et al. 2013). Binds inositol phosphate with low Kd and inositol with a lower affinity from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
29% identity, 88% coverage of query (95.5 bits)
TC 3.A.1.1.39 / Q9WYR1 Alpha-1,4-digalacturonate porter (Nanavati et al., 2006). Regulated by pectin utilization regulon UxaR from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
24% identity, 88% coverage of query (95.5 bits)
TC 3.A.1.1.6 / Q48397 CymG, component of Cyclodextrin porter from Klebsiella oxytoca (see paper)
23% identity, 88% coverage of query (94.4 bits)
PGA1_c13190 ABC transporter for D-Sorbitol, permease component 1 from Phaeobacter inhibens BS107
25% identity, 89% coverage of query (94.0 bits)
TC 3.A.1.1.5 / O30833 SmoG, component of Hexitol (glucitol; mannitol) porter from Rhodobacter sphaeroides (Rhodopseudomonas sphaeroides) (see paper)
27% identity, 89% coverage of query (91.3 bits)
TC 3.A.1.1.24 / Q72KX4 Sugar transport system permease protein aka TT_C0326, component of The glucose/mannose porter TTC0326-8 plus MalK1 (ABC protein, shared with 3.A.1.1.25) from Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) (see paper)
27% identity, 92% coverage of query (90.9 bits)
SMc02871 ABC transporter for N-Acetyl-D-glucosamine, permease protein 2 from Sinorhizobium meliloti 1021
25% identity, 93% coverage of query (90.1 bits)
PGA1_c27950 N-Acetyl-D-glucosamine ABC transport system, permease component 2 from Phaeobacter inhibens BS107
25% identity, 97% coverage of query (89.4 bits)
Ac3H11_2065 glucose ABC transporter, permease component 2 from Acidovorax sp. GW101-3H11
28% identity, 94% coverage of query (86.7 bits)
ARAQ_BACSU / P94530 Arabinooligosaccharides transport system permease protein AraQ from Bacillus subtilis (strain 168) (see 3 papers)
TC 3.A.1.1.34 / P94530 L-arabinose transport system permease protein AraQ, component of The arabinosaccharide transporter AraNPQMsmX. Transports α-1,5-arabinooligosaccharides, at least up to four L-arabinosyl units; the key transporter for α-1,5-arabinotriose and α-1,5-arabinotetraose, but not for α-1,5-arabinobiose which is transported by AraE. MsmX is also used by the MdxEFG-MsmX system (3.A.1.1.36) (Ferreira and Sá-Nogueira, 2010). Involved in the uptake of pectin oligosaccharides with either MsmX or YurJ as the ATPase from Bacillus subtilis (see 5 papers)
25% identity, 89% coverage of query (86.3 bits)
YTCP_BACSU / P53561 Polygalacturonan/rhamnogalacturonan transport system permease protein YtcP from Bacillus subtilis (strain 168) (see paper)
27% identity, 92% coverage of query (85.9 bits)
NGCG_STRCO / O50501 Diacetylchitobiose uptake system permease protein NgcG from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) (see paper)
25% identity, 88% coverage of query (84.0 bits)
TC 3.A.1.1.35 / G3LHZ1 GlpQ, component of Glycerol uptake porter, GlpSTPQV from Rhizobium leguminosarum bv. viciae
26% identity, 89% coverage of query (83.2 bits)
Q9X0S9 ABC-type maltose transporter (subunit 2/2) (EC 7.5.2.1) from Thermotoga maritima (see paper)
TC 3.A.1.1.22 / Q9X0S9 MalG1; aka Maltose ABC transporter, permease protein, component of The maltose, maltotriose, mannotetraose (MalE1)/maltose, maltotriose, trehalose (MalE2) porter (Nanavati et al., 2005). For MalG1 (823aas) and MalG2 (833aas), the C-terminal transmembrane domain with 6 putative TMSs is preceded by a single N-terminal TMS and a large (600 residue) hydrophilic region showing sequence similarity to MLP1 and 2 (9.A.14; e-12 & e-7) as well as other proteins from Thermotoga maritima (see paper)
30% identity, 72% coverage of query (82.0 bits)
TC 3.A.1.1.20 / Q7WWQ8 Transmembrane permease MsmG, component of The fructooligosaccharide porter, MsmEFGK from Lactobacillus acidophilus (see 2 papers)
msmG / GI|33149340 transmembrane permease MsmG from Lactobacillus acidophilus (see paper)
24% identity, 90% coverage of query (81.3 bits)
Ac3H11_2942 ABC transporter for D-Sorbitol, permease component 1 from Acidovorax sp. GW101-3H11
26% identity, 89% coverage of query (78.2 bits)
TC 3.A.1.1.16 / Q8TZQ0 MalG, component of Maltooligosaccharide porter (Maltose is not a substrate, but maltotriose is.) from Pyrococcus furiosus
28% identity, 75% coverage of query (77.8 bits)
TC 3.A.1.1.48 / D6ZW62 Permease of ABC transporter for sugars, component of The lacto-N-biose I (LNB; Gal β-1,3-GlcNAc)/galacto-N-biose (GNB; Gal β-1,3-GalNAc) transporter from Bifidobacterium longum subsp. longum (strain JDM301)
27% identity, 89% coverage of query (77.8 bits)
TC 3.A.1.1.11 / Q93KB9 TogN, component of Saturated and unsaturated oligogalacturonide transporter, TogMNAB (transports di- to tetrasaccharide pectin degradation products which consist of D-galacuronate, sometimes with 4-deoxy-L-threo-5-hexosulose uronate at the reducing end of the oligosaccharide) (Hugouvieux-Cotte-Pattat et al. 2001). Regulated by pectin utilization regulator KdgR from Erwinia chrysanthemi (see paper)
24% identity, 97% coverage of query (77.0 bits)
PfGW456L13_1896 ABC transporter for D-Galactose and D-Glucose, permease component 2 from Pseudomonas fluorescens GW456-L13
25% identity, 97% coverage of query (73.2 bits)
TC 3.A.1.1.28 / Q00751 MsmG aka SMU.880, component of The raffinose/stachyose transporter, MsmEFGK (MalK (3.A.1.1.27) can probably substitute for MsmK; Webb et al., 2008). This system may also transport melibiose, isomaltotriose and sucrose as well as isomaltosaccharides from Streptococcus mutans (see 2 papers)
27% identity, 86% coverage of query (73.2 bits)
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Lawrence Berkeley National Laboratory