Searching for up to 100 curated homologs for RR42_RS23435 FitnessBrowser__Cup4G11:RR42_RS23435 (317 a.a.)

Found high-coverage hits (≥70%) to 34 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

dhaL / Q0K7D4 L-dehydro-ascorbate lactonase from Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337) (see 2 papers)
    43% identity, 88% coverage of query (219 bits)

3dr2A / B0RN69 Structural and functional analyses of xc5397 from xanthomonas campestris: a gluconolactonase important in glucose secondary metabolic pathways (see paper)
    42% identity, 83% coverage of query (179 bits)

3e5zA / Q9RXN3 X-ray structure of the putative gluconolactonase in protein family pf08450. Northeast structural genomics consortium target drr130.
    37% identity, 93% coverage of query (170 bits)

gnl / Q01578 gluconolactonase subunit (EC 3.1.1.17) from Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) (see paper)
GNL_ZYMMO / Q01578 Gluconolactonase; D-glucono-delta-lactone lactonohydrolase; EC 3.1.1.17 from Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) (see paper)
Q01578 gluconolactonase (EC 3.1.1.17) from Zymomonas mobilis subsp. mobilis (see paper)
    33% identity, 94% coverage of query (140 bits)

B2LYJ5 1,4-lactonase (EC 3.1.1.25) from Fusarium proliferatum (see paper)
    30% identity, 72% coverage of query (94.0 bits)

uxuL / B2UIY8 D-galactaro-1,5-lactonase/D-glucaro-1,5-lactonase from Ralstonia pickettii (strain 12J) (see paper)
    30% identity, 80% coverage of query (85.5 bits)

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Build an alignment for RR42_RS23435 and 6 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

PP_1170 D-glucaro-1,5-lactonase UxuL from Pseudomonas putida KT2440
    28% identity, 80% coverage of query (76.3 bits)

xacC / D4GP31 D-xylono/L-arabinono-1,4-lactonase (EC 3.1.1.15; EC 3.1.1.68) from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (see 5 papers)
XACC_HALVD / D4GP31 Pentonolactonase XacC; L-arabinonolactonase; Xylono-1,4-lactonase; EC 3.1.1.15; EC 3.1.1.68 from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see paper)
D4GP31 L-arabinonolactonase (EC 3.1.1.15); xylono-1,4-lactonase (EC 3.1.1.68) from Haloferax volcanii (see 2 papers)
    28% identity, 83% coverage of query (75.5 bits)

ORYL_ASPOR / Q2TXF9 Lactonohydrolase oryL; Oryzines biosynthesis cluster protein L; EC 3.1.1.- from Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold) (see paper)
    24% identity, 79% coverage of query (72.0 bits)

PS417_17365 galactaro-1,5-lactonase from Pseudomonas simiae WCS417
    28% identity, 80% coverage of query (69.7 bits)

xylC / A0A0H3C6P8 xylono-1,5-lactonase (EC 3.1.1.110) from Caulobacter vibrioides (strain NA1000 / CB15N) (see 2 papers)
XYLC_CAUVC / Q9A9Z1 D-xylonolactone lactonase; Xylono-1,5-lactonase; EC 3.1.1.110 from Caulobacter vibrioides (strain ATCC 19089 / CB15) (Caulobacter crescentus) (see 4 papers)
Q9A9Z1 xylono-1,5-lactonase (EC 3.1.1.110) from Caulobacter vibrioides (see 4 papers)
    29% identity, 81% coverage of query (67.4 bits)

7plbB / Q9A9Z1 Caulobacter crescentus xylonolactonase with d-xylose (see paper)
    29% identity, 81% coverage of query (67.4 bits)

7pldB Caulobacter crescentus xylonolactonase with (r)-4-hydroxy-2- pyrrolidone
    29% identity, 81% coverage of query (67.4 bits)

8dk0A Crystal structure of rpa3624, a beta-propeller lactonase from rhodopseudomonas palustris, with active-site bound (s)gamma- valerolactone
    26% identity, 80% coverage of query (64.7 bits)

8djzA Crystal structure of rpa3624, a beta-propeller lactonase from rhodopseudomonas palustris, with active-site bound product
    26% identity, 80% coverage of query (64.7 bits)

8djfA Crystal structure of rpa3624, a beta-propeller lactonase from rhodopseudomonas palustris, with active-site bound tetrahedral intermediate
    26% identity, 80% coverage of query (64.7 bits)

Ga0059261_1893 Xylonolactonase (EC 3.1.1.68) from Sphingomonas koreensis DSMZ 15582
    29% identity, 83% coverage of query (63.5 bits)

Rgn / Q03336 gluconolactonase (EC 3.1.1.17) from Rattus norvegicus (see 3 papers)
RGN_RAT / Q03336 Regucalcin; RC; Gluconolactonase; GNL; Senescence marker protein 30; SMP-30; EC 3.1.1.17 from Rattus norvegicus (Rat) (see 4 papers)
Q03336 diisopropyl-fluorophosphatase (EC 3.1.8.2) from Rattus norvegicus (see paper)
    25% identity, 81% coverage of query (62.8 bits)

7risA Crystal structure of rpa3624, a beta-propeller lactonase from rhodopseudomonas palustris, with active-site bound phosphate
    25% identity, 80% coverage of query (61.2 bits)

7rizA / Q6N3R9 Crystal structure of rpa3624, a beta-propeller lactonase from rhodopseudomonas palustris, with active-site bound 2-hydroxyquinoline (see paper)
    26% identity, 80% coverage of query (59.7 bits)

4gncA / Q15493 Human smp30/gnl-1,5-ag complex (see paper)
    25% identity, 81% coverage of query (59.3 bits)

RGN_HUMAN / Q15493 Regucalcin; RC; Gluconolactonase; GNL; Senescence marker protein 30; SMP-30; EC 3.1.1.17 from Homo sapiens (Human) (see 2 papers)
Q15493 gluconolactonase (EC 3.1.1.17) from Homo sapiens (see paper)
    25% identity, 81% coverage of query (59.3 bits)

3g4hA Crystal structure of human senescence marker protein-30 (zinc bound)
    25% identity, 81% coverage of query (59.3 bits)

4gnaA Mouse smp30/gnl-xylitol complex
    24% identity, 81% coverage of query (58.5 bits)

4gn9A Mouse smp30/gnl-glucose complex
    24% identity, 81% coverage of query (58.5 bits)

4gn8A Mouse smp30/gnl-1,5-ag complex
    24% identity, 81% coverage of query (58.5 bits)

4gn7A / Q64374 Mouse smp30/gnl (see paper)
    24% identity, 81% coverage of query (58.5 bits)

SGL_PSEPU / P0DOV6 6-deoxy-6-sulfogluconolactonase; 6-deoxy-6-sulfogluconolactone lactonase; SGL lactonase; EC 3.1.1.99 from Pseudomonas putida (Arthrobacter siderocapsulatus) (see paper)
    26% identity, 80% coverage of query (58.2 bits)

RGN_XENLA / Q9I922 Regucalcin; RC; Gluconolactonase; GNL; Senescence marker protein 30; SMP-30; xSMP-30; EC 3.1.1.17 from Xenopus laevis (African clawed frog) (see paper)
    26% identity, 80% coverage of query (57.8 bits)

HSERO_RS05225 L-arabinolactonase (EC 3.1.1.15) from Herbaspirillum seropedicae SmR1
    25% identity, 80% coverage of query (53.9 bits)

2dsoC / Q99QV3 Crystal structure of d138n mutant of drp35, a 35kda drug responsive protein from staphylococcus aureus (see paper)
    26% identity, 71% coverage of query (48.5 bits)

DRP35_STAAU / Q9S0S3 Lactonase drp35; EC 3.1.1.- from Staphylococcus aureus (see paper)
    26% identity, 71% coverage of query (47.8 bits)

Pf1N1B4_413 L-arabinolactonase (EC 3.1.1.15) from Pseudomonas fluorescens FW300-N1B4
    25% identity, 81% coverage of query (47.4 bits)

DRP35_STAAN / Q7A338 Lactonase drp35; EC 3.1.1.- from Staphylococcus aureus (strain N315) (see paper)
DRP35_STAAM / Q99QV3 Lactonase drp35; EC 3.1.1.- from Staphylococcus aureus (strain Mu50 / ATCC 700699) (see paper)
    26% identity, 71% coverage of query (46.6 bits)

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