Searching for up to 100 curated homologs for RR42_RS25025 FitnessBrowser__Cup4G11:RR42_RS25025 (256 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
HSERO_RS00895 L-proline ABC transporter, ATPase component 1 from Herbaspirillum seropedicae SmR1
44% identity, 97% coverage of query (215 bits)
TC 3.A.1.4.10 / Q8DQH8 ABC transporter ATP-binding protein-branched chain amino acid transport, component of The branched chain hydrophobic amino acid transporter, LivJFGHM from Streptococcus pneumoniae (strain ATCC BAA-255 / R6)
41% identity, 97% coverage of query (197 bits)
Ac3H11_1693 ABC transporter for glutamine/isoleucine/leucine/phenylalanine/proline/serine/tyrosine, ATPase component 1 from Acidovorax sp. GW101-3H11
40% identity, 97% coverage of query (197 bits)
Pf6N2E2_2925 ABC transporter for L-leucine/L-isoleucine/L-phenylalanine/D-alanine, ATPase component 1 LivG from Pseudomonas fluorescens FW300-N2E2
38% identity, 97% coverage of query (189 bits)
TC 3.A.1.4.11 / Q6N8W1 Putative branched-chain amino acid transport system ATP-binding protein, component of The phenylpropeneoid uptake porter, CouPSTW from Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009)
40% identity, 98% coverage of query (188 bits)
TC 3.A.1.4.8 / P21629 High-affinity branched-chain amino acid transport ATP-binding protein BraF, component of Branched chain amino acid uptake transporter. Transports alanine from Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
38% identity, 97% coverage of query (187 bits)
TC 3.A.1.4.2 / Q55164 NatA aka BRAF aka SLR0467, component of Leucine/proline/alanine/serine/glycine (and possibly histidine) porter, NatABCDE (see paper)
40% identity, 95% coverage of query (181 bits)
LivG / b3455 branched chain amino acid/phenylalanine ABC transporter ATP binding subunit LivG (EC 7.4.2.2) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
LivG / P0A9S7 branched chain amino acid/phenylalanine ABC transporter ATP binding subunit LivG (EC 7.4.2.2) from Escherichia coli (strain K12) (see 3 papers)
TC 3.A.1.4.1 / P0A9S7 High-affinity branched-chain amino acid transport ATP-binding protein LivG aka B3455, component of Leucine; leucine/isoleucine/valine porter from Escherichia coli (see 4 papers)
37% identity, 97% coverage of query (181 bits)
TC 3.A.1.4.6 / Q7A2H0 NatA, component of The neutral amino acid permease, N-1 (transports pro, phe, leu, gly, ala, ser, gln and his, but gln and his are not transported via NatB) (see paper)
38% identity, 97% coverage of query (179 bits)
braF / CAB75551.1 ATPase from Rhizobium leguminosarum bv. viciae (see 2 papers)
38% identity, 100% coverage of query (169 bits)
AZOBR_RS08245 L-proline and D-alanine ABC transporter, ATPase component 1 from Azospirillum brasilense Sp245
40% identity, 98% coverage of query (169 bits)
TC 3.A.1.4.9 / Q0S719 ABC amino acid transporter, ATP-binding, component of Uptake transporter, CamABCD of cholate (steroid) metabolites, 1β(2'-propanoate)-3aα-H-4α(3"(R)-hydroxy-3"-propanoate)-7aβ-methylhexahydro-5-indanone and a desaturated analog from Rhodococcus sp. (strain RHA1)
36% identity, 100% coverage of query (160 bits)
1g9xB Characterization of the twinning structure of mj1267, an atp-binding cassette of an abc transporter
33% identity, 97% coverage of query (157 bits)
1g6hA / Q58663 Crystal structure of the adp conformation of mj1267, an atp-binding cassette of an abc transporter (see paper)
33% identity, 97% coverage of query (156 bits)
TC 3.A.1.4.7 / Q92TN3 ABC transporter, ATP-binding protein, component of The protocatechuate (3,4-dihydroxybenzoate) uptake porter, PcaMNVWX from Rhizobium meliloti (strain 1021)
42% identity, 94% coverage of query (155 bits)
PGA1_c12640 D-lactate transporter, ATP-binding component from Phaeobacter inhibens BS107
32% identity, 97% coverage of query (140 bits)
6mjpA / O30650 Lptb(e163q)fgc from vibrio cholerae (see paper)
32% identity, 97% coverage of query (140 bits)
A0A071L2Z5 ABC-type lipopolysaccharide transporter (EC 7.5.2.5) from Pseudomonas aeruginosa (see paper)
TC 3.A.1.152.1 / Q9HVV6 Probable ATP-binding component of ABC transporter, component of LPS export system, LptF (M), LptG (M) and LptB (C) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
32% identity, 96% coverage of query (140 bits)
TC 3.A.1.4.3 / Q8VM83 BraF aka Bra2F, component of General L- (and D-)amino acid uptake porter (transports acidic, basic, polar, semipolar and hydrophobic amino acids). The amino and carboxyl groups do not need to be α since γ-aminobutyric acid (GABA) is a substrate. The system may function with additional binding proteins since L-alanine uptake is not dependent on BraC from Rhizobium leguminosarum (biovar viciae) (see paper)
35% identity, 97% coverage of query (140 bits)
lptB / Q7CPN9 LPS export ABC transporter ATP-binding protein (EC 7.5.2.5) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 9 papers)
33% identity, 95% coverage of query (140 bits)
ARGV_CORGL / Q8NQU4 Arginine transport ATP-binding protein ArgV; EC 7.4.2.1 from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see paper)
31% identity, 94% coverage of query (132 bits)
TC 3.A.1.4.5 / Q8NRV8 UrtD, component of The high affinity urea/thiourea/hydroxyurea porter from Corynebacterium glutamicum (see paper)
34% identity, 97% coverage of query (129 bits)
GlnQ / b0809 L-glutamine ABC transporter ATP binding subunit (EC 7.4.2.1) from Escherichia coli K-12 substr. MG1655 (see 2 papers)
GlnQ / P10346 L-glutamine ABC transporter ATP binding subunit (EC 7.4.2.1) from Escherichia coli (strain K12) (see paper)
GLNQ_ECOLI / P10346 Glutamine transport ATP-binding protein GlnQ from Escherichia coli (strain K12) (see paper)
TC 3.A.1.3.2 / P10346 GlnQ aka B0809, component of Three component ABC L-glutamine porter. The basal ATPase activity (ATP hydrolysis in the absence of substrate) is mainly caused by the docking of the closed-unliganded state of GlnH onto the transporter domain of GlnPQ. Unlike glutamine, arginine binds both GlnH domains, but does not trigger their closing. Comparison of the ATPase activity in nanodiscs with glutamine transport in proteoliposomes suggested that the stoichiometry of ATP per substrate is close to two from Escherichia coli (see 5 papers)
glnQ / GB|ABB65374.1 glutamine ABC transporter, ATP-binding protein GlnQ from Escherichia coli K12 (see 5 papers)
31% identity, 94% coverage of query (129 bits)
lptB / Q2YP14 lipopolysaccharide transport system ATP-binding protein (EC 7.5.2.5) from Brucella abortus (strain 2308) (see paper)
31% identity, 95% coverage of query (128 bits)
Build an alignment for RR42_RS25025 and 24 homologs with ≥ 30% identity
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RbsA / b3749 ribose ABC transporter ATP binding subunit from Escherichia coli K-12 substr. MG1655 (see 5 papers)
RbsA / P04983 ribose ABC transporter ATP binding subunit from Escherichia coli (strain K12) (see 2 papers)
RBSA_ECOLI / P04983 Ribose import ATP-binding protein RbsA; EC 7.5.2.7 from Escherichia coli (strain K12) (see 3 papers)
TC 3.A.1.2.1 / P04983 RbsA aka B3749, component of Ribose porter from Escherichia coli (see 6 papers)
rbsA / GB|AAC76772.1 ribose transport, ATP-binding protein RbsA; EC 3.6.3.17 from Escherichia coli K12 (see 7 papers)
28% identity, 95% coverage of query (128 bits)
LptB / b3201 lipopolysaccharide transport system ATP binding protein LptB (EC 7.5.2.5) from Escherichia coli K-12 substr. MG1655 (see 12 papers)
LptB / P0A9V1 lipopolysaccharide transport system ATP binding protein LptB (EC 7.5.2.5) from Escherichia coli (strain K12) (see 10 papers)
LPTB_ECOLI / P0A9V1 Lipopolysaccharide export system ATP-binding protein LptB; EC 7.5.2.- from Escherichia coli (strain K12) (see 5 papers)
P0A9V1 ABC-type lipopolysaccharide transporter (EC 7.5.2.5) from Escherichia coli (see 3 papers)
TC 1.B.42.1.2 / P0A9V1 Lipopolysaccharide export system ATP-binding protein LptB, component of LPS export porin complex, LptBCFG-A-DE, consists of LptD (Omp; OmpA; 784 aas)-LptE (RlpB; 193 aas; O.M. lipoprotein)-LptA (KdsD; YhbN; OstA small; 185 aas periplasmic chaparone protein)-LptB (KdsC; YhbG; 241 aas cytoplasmic ABC-type ATPase)-LptC (YrbK, 199aas;1 N-terminal TMS)- LptFG, part of the ABC transporter. LptDE (1:1 stoichiometry) comprise a two-protein β-barrel-lipoprotein complex in the outer membrane that assembles and exports LPS from Escherichia coli (strain K12)
lptB lipopolysaccharide ABC transporter, ATP-binding protein LptB; EC 3.6.3.- from Escherichia coli K12 (see 9 papers)
33% identity, 95% coverage of query (128 bits)
6s8nB Cryo-em structure of lptb2fgc in complex with lipopolysaccharide
33% identity, 95% coverage of query (128 bits)
6s8gA Cryo-em structure of lptb2fgc in complex with amp-pnp
33% identity, 95% coverage of query (128 bits)
6mhzA Vanadate trapped cryo-em structure of e.Coli lptb2fg transporter
33% identity, 95% coverage of query (128 bits)
4u00A / Q5SJ55 Crystal structure of ttha1159 in complex with adp (see paper)
30% identity, 94% coverage of query (127 bits)
6mbnA / P0A9V1 Lptb e163q in complex with atp (see paper)
33% identity, 95% coverage of query (126 bits)
E6MYT4 ABC-type lipopolysaccharide transporter (EC 7.5.2.5) from Neisseria meningitidis serogroup B / serotype 15 (see 2 papers)
31% identity, 94% coverage of query (126 bits)
6b89A E. Coli lptb in complex with adp and novobiocin
33% identity, 94% coverage of query (125 bits)
4p31A Crystal structure of a selenomethionine derivative of e. Coli lptb in complex with adp-magensium
33% identity, 94% coverage of query (125 bits)
6b8bA E. Coli lptb in complex with adp and a novobiocin derivative
33% identity, 94% coverage of query (124 bits)
1ji0A / Q9X0M3 Crystal structure analysis of the abc transporter from thermotoga maritima
30% identity, 93% coverage of query (123 bits)
TC 3.A.1.2.20 / G4FGN3 Monosaccharide-transporting ATPase, component of Glucose porter. Also bind xylose (Boucher and Noll 2011). Induced by glucose (Frock et al. 2012). Directly regulated by glucose-responsive regulator GluR from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
26% identity, 96% coverage of query (120 bits)
3c4jA Abc protein artp in complex with atp-gamma-s
27% identity, 94% coverage of query (114 bits)
3c41J / D0VWX4 Abc protein artp in complex with amp-pnp/mg2+
27% identity, 94% coverage of query (114 bits)
2olkA Abc protein artp in complex with adp-beta-s
27% identity, 94% coverage of query (114 bits)
2oljA Abc protein artp in complex with adp/mg2+
27% identity, 94% coverage of query (114 bits)
4ymuJ / Q8RCC2 Crystal structure of an amino acid abc transporter complex with arginines and atps (see paper)
25% identity, 93% coverage of query (106 bits)
6z5uK Cryo-em structure of the a. Baumannii mlabdef complex bound to appnhp
32% identity, 90% coverage of query (105 bits)
7d0aB Acinetobacter mlafedb complex in adp-vanadate trapped vclose conformation
32% identity, 91% coverage of query (105 bits)
7d08B / A0A086HZU3 Acinetobacter mlafedb complex in atp-bound vtrans1 conformation (see paper)
32% identity, 91% coverage of query (105 bits)
PotA / b1126 spermidine preferential ABC transporter ATP binding subunit (EC 7.6.2.11; EC 7.6.2.16) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
PotA / P69874 spermidine preferential ABC transporter ATP binding subunit (EC 7.6.2.11) from Escherichia coli (strain K12) (see 5 papers)
POTA_ECOLI / P69874 Spermidine/putrescine import ATP-binding protein PotA; EC 7.6.2.11 from Escherichia coli (strain K12) (see 6 papers)
TC 3.A.1.11.1 / P69874 Spermidine/putrescine import ATP-binding protein PotA aka B1126, component of Polyamine (putrescine/spermidine) uptake porter from Escherichia coli (see 9 papers)
potA / MB|P69874 spermidine/putrescine ABC transporter, ATP-binding protein PotA; EC 3.6.3.31 from Escherichia coli K12 (see 10 papers)
27% identity, 95% coverage of query (103 bits)
P9WQK5 Uncharacterized ABC transporter ATP-binding protein Rv0073 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
33% identity, 77% coverage of query (102 bits)
FtsE / b3463 cell division protein FtsE from Escherichia coli K-12 substr. MG1655 (see 9 papers)
FTSE_ECOLI / P0A9R7 Cell division ATP-binding protein FtsE from Escherichia coli (strain K12) (see 4 papers)
ftsE cell division ATP-binding protein ftsE from Escherichia coli K12 (see 3 papers)
29% identity, 88% coverage of query (100 bits)
8w6iD / P0A9R7 Cryo-em structure of escherichia coli str k12 ftsex complex with atp- gamma-s in peptidisc
29% identity, 88% coverage of query (100 bits)
MetN / b0199 L-methionine/D-methionine ABC transporter ATP binding subunit (EC 7.4.2.11) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
MetN / P30750 L-methionine/D-methionine ABC transporter ATP binding subunit (EC 7.4.2.11) from Escherichia coli (strain K12) (see 3 papers)
METN_ECOLI / P30750 Methionine import ATP-binding protein MetN; EC 7.4.2.11 from Escherichia coli (strain K12) (see 7 papers)
P30750 ABC-type methionine transporter (subunit 2/2) (EC 7.4.2.11) from Escherichia coli (see 3 papers)
TC 3.A.1.24.1 / P30750 MetN, D-methionine transport ATP-binding protein, component of The L- and D-methionine porter (also transports formyl-L-methionine and other methionine derivatives) (Zhang et al., 2003). The 3.7A structure of MetNI has been solved. An allosteric regulatory mechanism operates at the level of transport activity, so increased intracellular levels of the transported ligand stabilize an inward-facing, ATPase-inactive state of MetNI to inhibit further ligand translocation into the cell from Escherichia coli (see 5 papers)
28% identity, 94% coverage of query (99.0 bits)
8hd0A Cell divisome spg hydrolysis machinery ftsex-envc
29% identity, 88% coverage of query (99.0 bits)
3tuzC Inward facing conformations of the metni methionine abc transporter: cy5 semet soak crystal form
28% identity, 94% coverage of query (97.8 bits)
3tuiC Inward facing conformations of the metni methionine abc transporter: cy5 native crystal form
28% identity, 94% coverage of query (97.8 bits)
6cvlD / P30750 Crystal structure of the escherichia coli atpgs-bound metni methionine abc transporter in complex with its metq binding protein (see paper)
28% identity, 94% coverage of query (97.4 bits)
1b0uA / P02915 Atp-binding subunit of the histidine permease from salmonella typhimurium (see paper)
30% identity, 93% coverage of query (97.1 bits)
HISP_SALTY / P02915 Histidine/lysine/arginine/ornithine transport ATP-binding protein HisP; EC 7.4.2.1 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 4 papers)
TC 3.A.1.3.1 / P02915 HisP aka STM2351, component of Histidine/arginine/lysine/ornithine porter (Heuveling et al. 2014). In contrast to some homologous homodimeric systems, the heterodimeric histidine transporter of Salmonella enterica Typhimurium from Salmonella typhimurium (see 3 papers)
RF|NP_461293.1 histidine transport atp-binding protein hisp from Salmonella enterica subsp. enterica serovar Typhimurium (see 4 papers)
30% identity, 93% coverage of query (97.1 bits)
ABC1_MYCTU / O65934 ABC transporter ATP-binding/permease protein Rv1747; EC 7.-.-.- from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 4 papers)
32% identity, 85% coverage of query (97.1 bits)
7lkpA Structure of atp-free human abca4
29% identity, 88% coverage of query (96.3 bits)
8f5bA / P78363 Human abca4 structure in complex with amp-pnp
29% identity, 88% coverage of query (96.3 bits)
ABCA4_HUMAN / P78363 Retinal-specific phospholipid-transporting ATPase ABCA4; ATP-binding cassette sub-family A member 4; RIM ABC transporter; RIM proteinv; RmP; Retinal-specific ATP-binding cassette transporter; Stargardt disease protein; EC 7.6.2.1 from Homo sapiens (Human) (see 38 papers)
TC 3.A.1.211.2 / P78363 The retinal-specific ABC transporter (RIM protein, ABCR or ABCA4) (Stargardt's disease protein, involved in retinal/macular degeneration) in the rod outer segment. Changes in the oligomeric state of the nucleotide binding domains of ABCR are coupled to ATP hydrolysis and might represent a signal for the TMDs of ABCR to export the bound substrate (Biswas-Fiss 2006). The ABCA4 porter flips N-retinylidene-phosphatidylethanolamine, a product generated from the photobleaching of rhodopsin, from the lumen to the cytoplasmic side of disc membranes following the photobleaching of rhodopsin, insuring that retinoids do not accumulate in disc membranes (Molday, 2007; Molday et al. 2009; Tsybovsky et al. 2013). It also transports several vitamin A derivatives (Sun, 2011) and phosphatidylethanolamine in the same direction. Mutations, known to cause Stargardt disease, decrease N-retinylidene-phosphatidylethanolamine and phosphatidylethanolamine transport activities (Quazi et al. 2012). It functions as an inwardly directed retinoid flippase in the visual cycle from Homo sapiens (Human) (see 28 papers)
29% identity, 88% coverage of query (95.9 bits)
7e7oA / P78363 Cryo-em structure of human abca4 in nrpe-bound state (see paper)
29% identity, 88% coverage of query (95.9 bits)
7lkzA Structure of atp-bound human abca4
29% identity, 88% coverage of query (95.1 bits)
7e7qA / P78363 Cryo-em structure of human abca4 in atp-bound state (see paper)
29% identity, 88% coverage of query (94.4 bits)
ABCA4_BOVIN / F1MWM0 Retinal-specific phospholipid-transporting ATPase ABCA4; ATP-binding cassette sub-family A member 4; RIM ABC transporter; RIM protein; RmP; Retinal-specific ATP-binding cassette transporter; EC 7.6.2.1 from Bos taurus (Bovine) (see 11 papers)
28% identity, 88% coverage of query (94.0 bits)
5x40A / O68106 Structure of a cbio dimer bound with amppcp (see paper)
33% identity, 95% coverage of query (93.6 bits)
8i6rB / Q9I6C0 Cryo-em structure of pseudomonas aeruginosa ftse(e163q)x/envc complex with atp in peptidisc (see paper)
28% identity, 91% coverage of query (92.4 bits)
6tejB / A0A100XE85 Structure of apo irtab devoid sid in complex with sybody syb_nl5 (see paper)
34% identity, 74% coverage of query (90.5 bits)
Q8TTZ3 ABC-type molybdate transporter (EC 7.3.2.5) from Methanosarcina acetivorans (see paper)
3d31A / Q8TTZ3 Modbc from methanosarcina acetivorans (see paper)
26% identity, 94% coverage of query (86.7 bits)
ABCBA_MOUSE / Q9JI39 ATP-binding cassette sub-family B member 10, mitochondrial; ABC-mitochondrial erythroid protein; ABC-me protein; ATP-binding cassette transporter 10; ABC transporter 10 protein from Mus musculus (Mouse) (see 9 papers)
31% identity, 89% coverage of query (85.9 bits)
2pclA / O66646 Crystal structure of abc transporter with complex (aq_297) from aquifex aeolicus vf5
28% identity, 90% coverage of query (85.5 bits)
1f3oA / Q58206 Crystal structure of mj0796 atp-binding cassette (see paper)
28% identity, 82% coverage of query (85.5 bits)
ABCAC_MOUSE / E9Q876 Glucosylceramide transporter ABCA12; ATP-binding cassette sub-family A member 12; EC 7.6.2.1 from Mus musculus (Mouse) (see 9 papers)
27% identity, 82% coverage of query (84.3 bits)
ABCAD_MOUSE / Q5SSE9 ATP-binding cassette sub-family A member 13; EC 7.6.2.- from Mus musculus (Mouse) (see 3 papers)
29% identity, 88% coverage of query (84.3 bits)
1l2tA Dimeric structure of mj0796, a bacterial abc transporter cassette
28% identity, 82% coverage of query (84.0 bits)
7qkrA / F2QQK6 Cryo-em structure of abc transporter ste6-2p from pichia pastoris with verapamil at 3.2 a resolution (see paper)
30% identity, 88% coverage of query (84.0 bits)
1oxvD Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus
27% identity, 93% coverage of query (84.0 bits)
1oxvA Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus
27% identity, 93% coverage of query (84.0 bits)
GLCV_SACS2 / Q97UY8 Glucose import ATP-binding protein GlcV; EC 7.5.2.- from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see 3 papers)
TC 3.A.1.1.13 / Q97UY8 GlcV, component of Glucose, mannose, galactose porter from Sulfolobus solfataricus (see 3 papers)
1oxuA / Q97UY8 Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus (see paper)
27% identity, 93% coverage of query (84.0 bits)
7chaI / Q9HVW1 Cryo-em structure of p.Aeruginosa mlafebd with amppnp (see paper)
25% identity, 87% coverage of query (83.2 bits)
ECFA2_STRT2 / Q5M244 Energy-coupling factor transporter ATP-binding protein EcfA2; ECF transporter A component EcfA2; EC 3.6.3.- from Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311) (see paper)
TC 3.A.1.25.6 / Q5M244 Energy-coupling factor transporter ATP-binding protein EcfA 1, component of Riboflavin ECF transport system, EcfAA'T/RibU from Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311)
27% identity, 93% coverage of query (82.8 bits)
7m1qA / P78363 Human abca4 structure in complex with n-ret-pe (see paper)
29% identity, 77% coverage of query (82.8 bits)
MacB / b0879 ABC-type tripartite efflux pump ATP binding/membrane subunit from Escherichia coli K-12 substr. MG1655 (see 14 papers)
MacB / P75831 ABC-type tripartite efflux pump ATP binding/membrane subunit from Escherichia coli (strain K12) (see 16 papers)
MACB_ECOLI / P75831 Macrolide export ATP-binding/permease protein MacB; EC 7.6.2.- from Escherichia coli (strain K12) (see 5 papers)
TC 3.A.1.122.1 / P75831 MacB aka B0879, component of Macrolide (14- and 15- but not 16-membered lactone macrolides including erythromycin) exporter, MacAB (formerly YbjYZ). Both MacA and MacB are required for activity (Tikhonova et al., 2007). MacAB functions with TolC to export multiple drugs and heat-stable enterotoxin II (enterotoxin STII) (Yamanaka et al., 2008). The crystal structure of MacA is available (Yum et al., 2009). MacB is a dimer whose ATPase activity and macrolide-binding capacity are regulated by the membrane fusion protein MacA (Lin et al., 2009). Xu et al. (2009) have reported the crystal structure of the periplasmic region of MacB which they claim resembles the periplasmic domain of RND-type transporters such as AcrB (TC# 2.A.6.2.2). Also exports L-cysteine (Yamada et al., 2006). The periplasmic membrane proximal domain of MacA acts as a switch in stimulation of ATP hydrolysis by the MacB transporter from Escherichia coli (see 5 papers)
macB / BAB64542.1 macrolide-specific ABC-type efflux carrier from Escherichia coli (see paper)
28% identity, 85% coverage of query (82.8 bits)
2d62A / O57933 Crystal structure of multiple sugar binding transport atp- binding protein
25% identity, 94% coverage of query (82.8 bits)
8iddA Cryo-em structure of mycobacterium tuberculosis atp bound ftsex/ripc complex in peptidisc
27% identity, 91% coverage of query (82.8 bits)
8igqA / O05779 Cryo-em structure of mycobacterium tuberculosis adp bound ftsex/ripc complex in peptidisc (see paper)
27% identity, 91% coverage of query (82.4 bits)
7mdyC Lolcde nucleotide-bound
27% identity, 90% coverage of query (82.4 bits)
LolD / b1117 lipoprotein release complex - ATP binding subunit from Escherichia coli K-12 substr. MG1655 (see 2 papers)
LolD / P75957 lipoprotein release complex - ATP binding subunit from Escherichia coli (strain K12) (see paper)
LOLD_ECOLI / P75957 Lipoprotein-releasing system ATP-binding protein LolD; EC 7.6.2.- from Escherichia coli (strain K12) (see paper)
TC 3.A.1.125.1 / P75957 LolD aka B1117, component of Lipoprotein translocation system (translocates lipoproteins from the inner membrane to periplasmic chaperone, LolA, which transfers the lipoproteins to an outer membrane receptor, LolB, which anchors the lipoprotein to the outer membrane of the Gram-negative bacterial cell envelope) (see 1.B.46; Narita et al., 2003; Ito et al., 2006; Watanabe et al., 2007). The structure of ligand-bound LolCDE has been solved (Ito et al., 2006). LolC and LolE each have 4 TMSs (1+3). Unlike most ATP binding cassette transporters mediating the transmembrane flux of substrates, the LolCDE complex catalyzes the extrusion of lipoproteins anchored to the outer leaflet of the inner membrane. The LolCDE complex is unusual in that it can be purified as a liganded form, which is an intermediate of the lipoprotein release reaction (Taniguchi and Tokuda, 2008). LolCDE has been reconstituted from separated subunits from Escherichia coli (see 5 papers)
lolD / GB|BAA35937.2 lipoprotein releasing system, ATP-binding protein; EC 3.6.3.- from Escherichia coli K12 (see 5 papers)
27% identity, 90% coverage of query (82.4 bits)
FTSE_MYCTA / A5U7B7 Cell division ATP-binding protein FtsE from Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra) (see 2 papers)
27% identity, 91% coverage of query (82.4 bits)
7wixB / P9WQJ7 Cryo-em structure of mycobacterium tuberculosis irtab in complex with adp
33% identity, 72% coverage of query (82.4 bits)
6z4wA / Q8DQH4 Ftse structure from streptococcus pneumoniae in complex with adp (space group p 1) (see paper)
23% identity, 88% coverage of query (82.4 bits)
6z67B Ftse structure of streptococcus pneumoniae in complex with amppnp at 2.4 a resolution
23% identity, 88% coverage of query (82.0 bits)
P0AAH0 Phosphate import ATP-binding protein PstB; ABC phosphate transporter; Phosphate-transporting ATPase; EC 7.3.2.1 from Escherichia coli (strain K12)
25% identity, 92% coverage of query (82.0 bits)
ABCA1_HUMAN / O95477 Phospholipid-transporting ATPase ABCA1; ATP-binding cassette sub-family A member 1; ATP-binding cassette transporter 1; ABC-1; ATP-binding cassette 1; Cholesterol efflux regulatory protein; EC 7.6.2.1 from Homo sapiens (Human) (see 34 papers)
TC 3.A.1.211.14 / O95477 cAMP-dependent and sulfonylurea-sensitive anion transporter, ABCA1 of 2261 aas. Key gatekeeper influencing and possibly catalyzing intracellular phospholipid and cholesterol transport from Homo sapiens
25% identity, 89% coverage of query (81.6 bits)
4ayxA / Q9NRK6 Structure of the human mitochondrial abc transporter, abcb10 (rod form b) (see paper)
29% identity, 89% coverage of query (81.6 bits)
ABCBA_HUMAN / Q9NRK6 ATP-binding cassette sub-family B member 10, mitochondrial; ABC-mitochondrial erythroid protein; ABC-me protein; ATP-binding cassette transporter 10; ABC transporter 10 protein; Mitochondrial ATP-binding cassette 2; M-ABC2 from Homo sapiens (Human) (see 7 papers)
Q9NRK6 bacterial ABC-type protein transporter (EC 7.4.2.5) from Homo sapiens (see paper)
29% identity, 89% coverage of query (81.3 bits)
7arlD Lolcde in complex with lipoprotein and adp
26% identity, 86% coverage of query (81.3 bits)
7v8iD / P75957 Lolcd(e171q)e with bound amppnp in nanodiscs (see paper)
26% identity, 90% coverage of query (81.3 bits)
8bmpB / Q1GBI9 Cryo-em structure of the folate-specific ecf transporter complex in msp2n2 lipid nanodiscs bound to atp and adp (see paper)
27% identity, 90% coverage of query (81.3 bits)
5d3mB Folate ecf transporter: amppnp bound state
27% identity, 90% coverage of query (81.3 bits)
8tzjA / A0A085R4L6 Cryo-em structure of vibrio cholerae ftse/ftsx complex (see paper)
25% identity, 86% coverage of query (81.3 bits)
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Lawrence Berkeley National Laboratory