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Searching for up to 100 curated homologs for RR42_RS25375 FitnessBrowser__Cup4G11:RR42_RS25375 (252 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

4xgnA / Q2T0K5 Crystal structure of 3-hydroxyacyl-coa dehydrogenase in complex with NAD from burkholderia thailandensis
    61% identity, 100% coverage of query (301 bits)

4o5oB / A0A0H3G6B0 X-ray crystal structure of a 3-hydroxyacyl-coa dehydrogenase from brucella suis
    60% identity, 100% coverage of query (279 bits)

fadB2x / Q88KS5 3-hydroxy-2-methylbutyryl-CoA dehydrogenase subunit (EC 1.1.1.178) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see 3 papers)
    57% identity, 100% coverage of query (265 bits)

HCD2_DROME / O18404 3-hydroxyacyl-CoA dehydrogenase type-2; 17-beta-hydroxysteroid dehydrogenase 10; 17-beta-HSD 10; 3-hydroxyacyl-CoA dehydrogenase type II; Hydroxysteroid dehydrogenase; Mitochondrial ribonuclease P protein 2; Mitochondrial RNase P protein 2; Scully protein; Type II HADH; EC 1.1.1.35; EC 1.1.1.51; EC 1.1.1.62; EC 1.1.1.-; EC 1.1.1.53 from Drosophila melanogaster (Fruit fly) (see 4 papers)
    51% identity, 98% coverage of query (244 bits)

6ujkA / P9WGQ7 Crystal structure of a probable short-chain type dehydrogenase/reductase (rv1144) from mycobacterium tuberculosis with bound NAD
    51% identity, 100% coverage of query (235 bits)

1u7tA Crystal structure of abad/hsd10 with a bound inhibitor
    52% identity, 96% coverage of query (232 bits)

HSD17B10 / Q99714 3-hydroxy-2-methylbutyryl-CoA dehydrogenase subunit (EC 1.1.1.35; EC 1.1.1.178; EC 1.1.1.239) from Homo sapiens (see 3 papers)
HCD2_HUMAN / Q99714 3-hydroxyacyl-CoA dehydrogenase type-2; 17-beta-estradiol 17-dehydrogenase; 2-methyl-3-hydroxybutyryl-CoA dehydrogenase; MHBD; 3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+)); 3-hydroxy-2-methylbutyryl-CoA dehydrogenase; 3-hydroxyacyl-CoA dehydrogenase type II; 3alpha(or 20beta)-hydroxysteroid dehydrogenase; 7-alpha-hydroxysteroid dehydrogenase; Endoplasmic reticulum-associated amyloid beta-peptide-binding protein; Mitochondrial ribonuclease P protein 2; Mitochondrial RNase P protein 2; Short chain dehydrogenase/reductase family 5C member 1; Short-chain type dehydrogenase/reductase XH98G2; Type II HADH; EC 1.1.1.35; EC 1.1.1.62; EC 1.1.1.239; EC 1.1.1.178; EC 1.1.1.53; EC 1.1.1.159 from Homo sapiens (Human) (see 22 papers)
Q99714 3-hydroxy-2-methylbutyryl-CoA dehydrogenase (EC 1.1.1.178) from Homo sapiens (see 2 papers)
    52% identity, 96% coverage of query (231 bits)

7onuC Structure of human mitochondrial rnase p in complex with mitochondrial pre-tRNA-tyr
    52% identity, 96% coverage of query (231 bits)

1e3wD / O70351 Rat brain 3-hydroxyacyl-coa dehydrogenase binary complex with nadh and 3-keto butyrate (see paper)
    50% identity, 96% coverage of query (228 bits)

O70351 3-hydroxyacyl-CoA dehydrogenase type-2; 17-beta-estradiol 17-dehydrogenase; 2-methyl-3-hydroxybutyryl-CoA dehydrogenase; MHBD; 3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+)); 3-hydroxy-2-methylbutyryl-CoA dehydrogenase; 3-hydroxyacyl-CoA dehydrogenase type II; 3alpha(or 20beta)-hydroxysteroid dehydrogenase; 7-alpha-hydroxysteroid dehydrogenase; Endoplasmic reticulum-associated amyloid beta-peptide-binding protein; Mitochondrial ribonuclease P protein 2; Mitochondrial RNase P protein 2; Short chain dehydrogenase/reductase family 5C member 1; Short-chain type dehydrogenase/reductase XH98G2; Type II HADH; EC 1.1.1.35; EC 1.1.1.62; EC 1.1.1.239; EC 1.1.1.178; EC 1.1.1.53; EC 1.1.1.159 from Rattus norvegicus (Rat)
    50% identity, 96% coverage of query (228 bits)

1uayA / Q7SIA1 Crystal structure of type ii 3-hydroxyacyl-coa dehydrogenase from thermus thermophilus hb8
    52% identity, 97% coverage of query (226 bits)

2o23B / Q99714 The structure of wild-type human hadh2 (17beta-hydroxysteroid dehydrogenase type 10) bound to NAD+ at 1.2 a
    51% identity, 96% coverage of query (220 bits)

HCD2_MOUSE / O08756 3-hydroxyacyl-CoA dehydrogenase type-2; 17-beta-estradiol 17-dehydrogenase; 2-methyl-3-hydroxybutyryl-CoA dehydrogenase; MHBD; 3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+)); 3-hydroxy-2-methylbutyryl-CoA dehydrogenase; 3-hydroxyacyl-CoA dehydrogenase type II; 3alpha(or 20beta)-hydroxysteroid dehydrogenase; 7-alpha-hydroxysteroid dehydrogenase; Endoplasmic reticulum-associated amyloid beta-peptide-binding protein; Mitochondrial ribonuclease P protein 2; Mitochondrial RNase P protein 2; Short chain dehydrogenase/reductase family 5C member 1; Short-chain type dehydrogenase/reductase XH98G2; Type II HADH; EC 1.1.1.35; EC 1.1.1.62; EC 1.1.1.239; EC 1.1.1.178; EC 1.1.1.53; EC 1.1.1.159 from Mus musculus (Mouse) (see paper)
    49% identity, 96% coverage of query (218 bits)

1e6wC Rat brain 3-hydroxyacyl-coa dehydrogenase binary complex with nadh and estradiol
    49% identity, 96% coverage of query (217 bits)

7n09A / F1L0H2 Structural basis for branched substrate selectivity in a ketoreductase from ascaris suum
    50% identity, 97% coverage of query (213 bits)

3ppiA / A0A0H3A4S5 Crystal structure of 3-hydroxyacyl-coa dehydrogenase type-2 from mycobacterium avium (see paper)
    44% identity, 100% coverage of query (189 bits)

IDOLDH / G5DGA8 ipsdienol dehydrogenase (EC 1.1.1.386) from Ips pini (see paper)
IDLDH_IPSPI / G5DGA8 Ipsdienol dehydrogenase; EC 1.1.1.386 from Ips pini (Pine engraver beetle) (see paper)
G5DGA8 ipsdienol dehydrogenase (EC 1.1.1.386) from Ips pini (see 2 papers)
    36% identity, 98% coverage of query (144 bits)

4nbuB Crystal structure of fabg from bacillus sp (see paper)
    37% identity, 98% coverage of query (139 bits)

SO1683 3-hydroxy-2-methylbutyryl-CoA dehydrogenase IvdG (EC:1.1.1.178) from Shewanella oneidensis MR-1
    36% identity, 99% coverage of query (120 bits)

PHAB_SYNY3 / P73826 Acetoacetyl-CoA reductase; EC 1.1.1.36 from Synechocystis sp. (strain PCC 6803 / Kazusa) (see paper)
    35% identity, 97% coverage of query (117 bits)

fabG / D4YGY5 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Aerococcus viridans (strain ATCC 11563 / DSM 20340 / CCUG 4311 / JCM 20461 / NBRC 12219 / NCTC 8251 / M1) (see paper)
    30% identity, 96% coverage of query (113 bits)

BWI76_RS23705 2-deoxy-D-ribonyl-CoA 3-dehydrogenase from Klebsiella michiganensis M5al
    33% identity, 97% coverage of query (110 bits)

G3XRE5 gluconate 5-dehydrogenase (EC 1.1.1.69) from Aspergillus niger (see paper)
    32% identity, 94% coverage of query (109 bits)

4cqlI / Q92506 Crystal structure of heterotetrameric human ketoacyl reductase complexed with NAD (see paper)
    32% identity, 96% coverage of query (108 bits)

7tzpG / A0A332H2K8 Crystal structure of putataive short-chain dehydrogenase/reductase (fabg) from klebsiella pneumoniae subsp. Pneumoniae ntuh-k2044 in complex with nadh (see paper)
    32% identity, 97% coverage of query (107 bits)

5itvA / P39640 Crystal structure of bacillus subtilis bacc dihydroanticapsin 7- dehydrogenase in complex with nadh (see paper)
    32% identity, 97% coverage of query (106 bits)

bacC / P39640 dihydroanticapsin dehydrogenase (EC 1.1.1.385) from Bacillus subtilis (strain 168) (see paper)
BACC_BACSU / P39640 Dihydroanticapsin 7-dehydrogenase; Bacilysin biosynthesis oxidoreductase BacC; EC 1.1.1.385 from Bacillus subtilis (strain 168) (see 3 papers)
P39640 dihydroanticapsin dehydrogenase (EC 1.1.1.385) from Bacillus subtilis (see paper)
    32% identity, 97% coverage of query (106 bits)

gutD / CAA05517.1 glucitol-6-phosphate dehydrogenase from Clostridium beijerinckii (see paper)
    30% identity, 91% coverage of query (106 bits)

HSD17B8 / Q92506 estradiol 17β-dehydrogenase 8 (EC 1.1.1.100) from Homo sapiens (see 4 papers)
DHB8_HUMAN / Q92506 (3R)-3-hydroxyacyl-CoA dehydrogenase; 17-beta-hydroxysteroid dehydrogenase 8; 17-beta-HSD 8; HSD17B8; 3-ketoacyl-[acyl-carrier-protein] reductase alpha subunit; KAR alpha subunit; 3-oxoacyl-[acyl-carrier-protein] reductase; Estradiol 17-beta-dehydrogenase 8; Protein Ke6; Ke6; Short chain dehydrogenase/reductase family 30C member 1; Testosterone 17-beta-dehydrogenase 8; EC 1.1.1.n12; EC 1.1.1.62; EC 1.1.1.239 from Homo sapiens (Human) (see 5 papers)
Q92506 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Homo sapiens (see paper)
    30% identity, 98% coverage of query (105 bits)

6ixmC / X2D0L0 Crystal structure of the ketone reductase chkred20 from the genome of chryseobacterium sp. Ca49 complexed with NAD (see paper)
    31% identity, 96% coverage of query (105 bits)

4cqmA Crystal structure of heterotetrameric human ketoacyl reductase complexed with NAD and NADP
    32% identity, 96% coverage of query (104 bits)

LINC_SPHIU / D4YYG1 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase; 2,5-DDOL dehydrogenase; EC 1.1.1.- from Sphingobium indicum (strain DSM 16413 / CCM 7287 / MTCC 6362 / UT26 / NBRC 101211 / UT26S) (Sphingobium japonicum) (see paper)
    34% identity, 97% coverage of query (103 bits)

lvr / Q9LBG2 levodione reductase monomer from Leifsonia aquatica (see 3 papers)
lvr / BAA95121.1 levodione reductase from Leifsonia aquatica (see paper)
    34% identity, 97% coverage of query (103 bits)

Q9LBG2 Levodione reductase; (6R)-2,2,6-trimethyl-1,4-cyclohexanedione reductase; EC 1.1.1.- from Leifsonia aquatica (Corynebacterium aquaticum)
    34% identity, 97% coverage of query (103 bits)

1iy8A / Q9LBG2 Crystal structure of levodione reductase (see paper)
    34% identity, 97% coverage of query (102 bits)

6qheA / A0A545BBS8 Alcohol dehydrogenase from arthrobacter sp. Ts-15 in complex with NAD+
    34% identity, 99% coverage of query (102 bits)

A0A545BBS8 pseudoephedrine dehydrogenase (EC 1.1.1.422) from Arthrobacter sp. TS-15 (see paper)
    34% identity, 99% coverage of query (102 bits)

Build an alignment

Build an alignment for RR42_RS25375 and 37 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

FABG_AQUAE / O67610 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Aquifex aeolicus (strain VF5)
    29% identity, 97% coverage of query (102 bits)

baiA3 / P07914 3α-hydroxysteroyl-CoA 3-dehydrogenase monomer (EC 1.1.1.395) from Clostridium scindens (strain JCM 10418 / VPI 12708) (see 8 papers)
BAIA1_CLOSV / P07914 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 1/3; 3alpha-hydroxysteroid dehydrogenase 1/3; 3alpha-HSDH 1/3; Bile acid-inducible protein BaiA1; Bile acid-inducible protein BaiA3; EC 1.1.1.395 from Clostridium scindens (strain JCM 10418 / VPI 12708) (see paper)
    32% identity, 98% coverage of query (102 bits)

4wecA / A0QVJ7 Crystal structure of a short chain dehydrogenase from mycobacterium smegmatis
    32% identity, 97% coverage of query (101 bits)

RUMGNA_02133 / A7B3K3 chenodeoxycholate 3α-dehydrogenase (EC 1.1.1.392) from Ruminococcus gnavus (strain ATCC 29149 / VPI C7-9) (see 4 papers)
3AHDP_RUMGV / A7B3K3 3alpha-hydroxysteroid dehydrogenase; 3alpha-HSDH; 3alpha-hydroxycholanate dehydrogenase (NADP(+)); NADP-dependent bile acid 3alpha-dehydrogenase; EC 1.1.1.-; EC 1.1.1.392 from Ruminococcus gnavus (strain ATCC 29149 / VPI C7-9) (see paper)
    32% identity, 98% coverage of query (100 bits)

baiA2 / P19337 3α-hydroxysteroid dehydrogenase 2 (EC 1.1.1.395) from Clostridium scindens (strain JCM 10418 / VPI 12708) (see 4 papers)
BAIA2_CLOSV / P19337 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2; 3alpha-hydroxysteroid dehydrogenase 2; 3alpha-HSDH 2; Bile acid-inducible protein BaiA2; EC 1.1.1.395 from Clostridium scindens (strain JCM 10418 / VPI 12708) (see paper)
P19337 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase (EC 1.1.1.395) from [Clostridium] scindens (see paper)
    31% identity, 98% coverage of query (99.8 bits)

4is3C / P19337 Crystal structure of a 3alpha-hydroxysteroid dehydrogenase (baia2) associated with secondary bile acid synthesis from clostridium scindens vpi12708 in complex with a putative NAD(+)-oh- adduct at 2.0 a resolution
    31% identity, 98% coverage of query (99.8 bits)

4cqmF / Q8N4T8 Crystal structure of heterotetrameric human ketoacyl reductase complexed with NAD and NADP (see paper)
    30% identity, 97% coverage of query (99.0 bits)

CBR4 / Q8N4T8 carbonyl reductase family member 4 (EC 1.1.1.100) from Homo sapiens (see 2 papers)
CBR4_HUMAN / Q8N4T8 3-oxoacyl-[acyl-carrier-protein] reductase; 3-ketoacyl-[acyl-carrier-protein] reductase beta subunit; KAR beta subunit; Carbonyl reductase family member 4; CBR4; Quinone reductase CBR4; Short chain dehydrogenase/reductase family 45C member 1; EC 1.1.1.100; EC 1.6.5.10 from Homo sapiens (Human) (see 3 papers)
    30% identity, 97% coverage of query (98.6 bits)

BN592_00769 / R7B6R4 3α-hydroxysteroid dehydrogenase (EC 1.1.1.52) from Eggerthella sp. CAG:298 (see paper)
R7B6R4 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific) (EC 1.1.1.213) from Eggerthella sp. CAG:298 (see paper)
    31% identity, 98% coverage of query (97.8 bits)

DHB8_RAT / Q6MGB5 (3R)-3-hydroxyacyl-CoA dehydrogenase; 17-beta-hydroxysteroid dehydrogenase 8; 17-beta-HSD 8; 3-ketoacyl-[acyl-carrier-protein] reductase alpha subunit; KAR alpha subunit; 3-oxoacyl-[acyl-carrier-protein] reductase; Estradiol 17-beta-dehydrogenase 8; Testosterone 17-beta-dehydrogenase 8; EC 1.1.1.n12; EC 1.1.1.62; EC 1.1.1.239 from Rattus norvegicus (Rat) (see paper)
    30% identity, 99% coverage of query (97.4 bits)

EASD_CLAFS / A8C7R7 Chanoclavine-I dehydrogenase easD; ChaDH; Ergot alkaloid synthesis protein D; EC 1.1.1.332 from Claviceps fusiformis (Ergot fungus) (see paper)
    34% identity, 89% coverage of query (97.4 bits)

5itvD / P39640 Crystal structure of bacillus subtilis bacc dihydroanticapsin 7- dehydrogenase in complex with nadh (see paper)
    30% identity, 97% coverage of query (97.4 bits)

Q1J2J0 L-iditol 2-dehydrogenase (EC 1.1.1.14) from Deinococcus geothermalis (see paper)
    33% identity, 94% coverage of query (96.7 bits)

5ts3A / C0RKU3 Crystal structure of a 3-oxoacyl-[acyl-carrier protein] reductase with bound NAD from brucella melitensis
    32% identity, 98% coverage of query (96.3 bits)

Q9SCU0 xanthoxin dehydrogenase (EC 1.1.1.288) from Arabidopsis thaliana (see paper)
    37% identity, 78% coverage of query (95.9 bits)

3ijrF / A0A6L8PL20 2.05 angstrom resolution crystal structure of a short chain dehydrogenase from bacillus anthracis str. 'Ames ancestor' in complex with NAD+
    33% identity, 95% coverage of query (95.9 bits)

3i3oA 2.06 angstrom resolution crystal structure of a short chain dehydrogenase from bacillus anthracis str. 'Ames ancestor' in complex with NAD-acetone
    33% identity, 95% coverage of query (95.9 bits)

5t5qC / Q2YL80 Crystal structure of short-chain dehydrogenase/reductase sdr:glucose/ribitol dehydrogenase from brucella melitensis
    29% identity, 99% coverage of query (95.5 bits)

srlD / Q9X671 sorbitol-6-phosphate dehydrogenase subunit (EC 1.1.1.140) from Streptococcus mutans (see 2 papers)
    31% identity, 94% coverage of query (95.5 bits)

GDH_RHIJ3 / Q1MLL4 Galactitol 2-dehydrogenase; GDH; RlGDH; EC 1.1.1.16 from Rhizobium johnstonii (strain DSM 114642 / LMG 32736 / 3841) (Rhizobium leguminosarum bv. viciae) (see paper)
Q1MLL4 galactitol 2-dehydrogenase (EC 1.1.1.16) from Rhizobium leguminosarum bv. viciae (see paper)
    35% identity, 94% coverage of query (94.7 bits)

cpnA / Q8GAV9 cyclopentanol dehydrogenase (EC 1.1.1.163) from Comamonas sp. (strain NCIMB 9872) (see 2 papers)
CPNA_COMS9 / Q8GAV9 Cyclopentanol dehydrogenase; Cyclohexanol dehydrogenase; EC 1.1.1.163; EC 1.1.1.245 from Comamonas sp. (strain NCIMB 9872) (see paper)
CPNA_COMTE / Q937L4 Cyclopentanol dehydrogenase; Cyclohexanol dehydrogenase; EC 1.1.1.163; EC 1.1.1.245 from Comamonas testosteroni (Pseudomonas testosteroni) (see paper)
cpmB / CAD10799.1 cyclohexanol dehydrogenase from Comamonas testosteroni (see paper)
    33% identity, 97% coverage of query (94.4 bits)

BWI76_RS01745 Sorbitol-6-phosphate 2-dehydrogenase (EC 1.1.1.140) from Klebsiella michiganensis M5al
    30% identity, 94% coverage of query (94.0 bits)

Q7XZH5 xanthoxin dehydrogenase (EC 1.1.1.288) from Oryza sativa (see paper)
    33% identity, 79% coverage of query (94.0 bits)

4nbtA / A9NFJ2 Crystal structure of fabg from acholeplasma laidlawii (see paper)
    29% identity, 98% coverage of query (93.6 bits)

Q4UN54 acetoacetyl-CoA reductase (EC 1.1.1.36) from Rickettsia felis (see paper)
    31% identity, 96% coverage of query (93.2 bits)

Q31QF3 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Synechococcus elongatus PCC 7942 = FACHB-805 (see paper)
    31% identity, 99% coverage of query (92.4 bits)

easD / M1VVW5 chanoclavine-I dehydrogenase monomer (EC 1.1.1.332) from Claviceps purpurea (strain 20.1) (see 2 papers)
EASD_CLAP2 / M1VVW5 Chanoclavine-I dehydrogenase easD; ChaDH; Ergot alkaloid synthesis protein D; Oxidoreductase 2; EC 1.1.1.332 from Claviceps purpurea (strain 20.1) (Ergot fungus) (Sphacelia segetum) (see 12 papers)
    34% identity, 89% coverage of query (92.4 bits)

BBSD_THAAR / Q9KJF1 (2S)-[(R)-hydroxy(phenyl)methyl]succinyl-CoA dehydrogenase subunit BbsD; (S,R)-2-(alpha-hydroxybenzyl)succinyl-CoA dehydrogenase subunit BbsD; EC 1.1.1.429 from Thauera aromatica (see 2 papers)
    33% identity, 97% coverage of query (92.4 bits)

uxaD / Q9WYS2 fructuronate reductase from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
    30% identity, 97% coverage of query (92.0 bits)

1vl8B / Q9WYS2 Crystal structure of gluconate 5-dehydrogenase (tm0441) from thermotoga maritima at 2.07 a resolution
    30% identity, 97% coverage of query (92.0 bits)

fabG / P51831 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Bacillus subtilis (strain 168) (see 3 papers)
    28% identity, 98% coverage of query (91.7 bits)

3op4A Crystal structure of putative 3-ketoacyl-(acyl-carrier-protein) reductase from vibrio cholerae o1 biovar eltor str. N16961 in complex with NADP+ (see paper)
    30% identity, 99% coverage of query (91.3 bits)

7pcsB / Q9KJF1 Structure of the heterotetrameric sdr family member bbscd (see paper)
    33% identity, 96% coverage of query (91.3 bits)

5t2uA / A0R723 Short chain dehydrogenase/reductase family protein (see paper)
    31% identity, 97% coverage of query (91.3 bits)

A0R723 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); acetoacetyl-CoA reductase (EC 1.1.1.36) from Mycolicibacterium smegmatis (see paper)
    31% identity, 97% coverage of query (91.3 bits)

1zk1A Structure of r-specific alcohol dehydrogenase (mutant g37d) from lactobacillus brevis in complex with phenylethanol and NAD
    29% identity, 97% coverage of query (90.1 bits)

1zjzA Structure of r-specific alcohol dehydrogenase (mutant g37d) from lactobacillus brevis in complex with phenylethanol and NAD
    29% identity, 97% coverage of query (90.1 bits)

1zjyA Structure of r-specific alcohol dehydrogenase (mutant g37d) from lactobacillus brevis in complex with phenylethanol and nadh
    29% identity, 97% coverage of query (90.1 bits)

3ak4A / G1K3P5 Crystal structure of nadh-dependent quinuclidinone reductase from agrobacterium tumefaciens
    34% identity, 96% coverage of query (90.1 bits)

SDR / F1SWA0 zerumbone synthase (EC 1.1.1.326) from Zingiber zerumbet (see paper)
ZERSY_ZINZE / F1SWA0 Zerumbone synthase; EC 1.1.1.326 from Zingiber zerumbet (Shampoo ginger) (Amomum zerumbet) (see paper)
F1SWA0 zerumbone synthase (EC 1.1.1.326) from Zingiber zerumbet (see 2 papers)
    30% identity, 99% coverage of query (90.1 bits)

5ha5D Crystal structure of an NAD-bound oxidoreductase from brucella ovis
    34% identity, 96% coverage of query (89.7 bits)

4dmmB / Q31QF3 3-oxoacyl-[acyl-carrier-protein] reductase from synechococcus elongatus pcc 7942 in complex with NADP
    30% identity, 99% coverage of query (89.4 bits)

7ejiB Crystal structure of kred f147l/l153q/y190p/l199a/m205f/m206f variant and methyl methacrylate complex
    32% identity, 87% coverage of query (89.4 bits)

7ejhA / Q6WVP7 Crystal structure of kred mutant-f147l/l153q/y190p/l199a/m205f/m206f and 2-hydroxyisoindoline-1,3-dione complex
    32% identity, 87% coverage of query (89.4 bits)

1nfqA Rv2002 gene product from mycobacterium tuberculosis
    33% identity, 97% coverage of query (88.6 bits)

1nffA / P9WGT1 Crystal structure of rv2002 gene product from mycobacterium tuberculosis (see paper)
    33% identity, 97% coverage of query (88.6 bits)

5h5xC / Q9KYM4 Crystal structure of nadh bound carbonyl reductase from streptomyces coelicolor
    35% identity, 94% coverage of query (88.6 bits)

4b79A / Q9HWT0 The aeropath project and pseudomonas aeruginosa high-throughput crystallographic studies for assessment of potential targets in early stage drug discovery. (see paper)
    31% identity, 97% coverage of query (88.6 bits)

budC / H9XP47 meso-butanediol dehydrogenase [(R)-acetoin-forming] (EC 1.1.1.304; EC 1.1.1.76) from Serratia marcescens (see paper)
MBDH_SERMA / H9XP47 Meso-2,3-butanediol dehydrogenase; BDH; meso-2,3-BDH; (R,S)-butane-2,3-diol dehydrogenase; NAD(H)-dependent meso-2,3-BDH; SmBdh; EC 1.1.1.- from Serratia marcescens (see 3 papers)
    29% identity, 97% coverage of query (88.6 bits)

HSD_MYCTU / P9WGT1 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase; NADH-dependent 3alpha, 20beta-hydroxysteroid dehydrogenase; EC 1.1.1.53 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
GI|3261591 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase; EC 1.1.1.53 from Mycobacterium tuberculosis H37Rv (see paper)
    33% identity, 95% coverage of query (87.8 bits)

xecD / Q56840 2-(R)-hydroxypropyl-CoM dehydrogenase subunit (EC 1.1.1.268) from Xanthobacter autotrophicus (strain ATCC BAA-1158 / Py2) (see 5 papers)
HCDR1_XANP2 / Q56840 2-(R)-hydroxypropyl-CoM dehydrogenase; R-HPCDH; 2-[(R)-2-hydroxypropylthio]ethanesulfonate dehydrogenase; Aliphatic epoxide carboxylation component III; Epoxide carboxylase component III; RHPCDH1; EC 1.1.1.268 from Xanthobacter autotrophicus (strain ATCC BAA-1158 / Py2) (see 7 papers)
Q56840 2-(R)-hydroxypropyl-CoM dehydrogenase (EC 1.1.1.268) from Xanthobacter autotrophicus (see 4 papers)
2cfcA / Q56840 Structural basis for stereo selectivity in the (r)- and (s)-hydroxypropylethane thiosulfonate dehydrogenases (see paper)
    33% identity, 95% coverage of query (87.8 bits)

RADH_LENKE / Q6WVP7 NADP-dependent (R)-specific alcohol dehydrogenase; (R)-specific ADH; Ketoreductase; KRED; EC 1.1.1.- from Lentilactobacillus kefiri (Lactobacillus kefiri)
    29% identity, 97% coverage of query (87.8 bits)

NEPS1_NEPRA / A0A3Q8GL18 (+)-cis,trans-nepetalactol synthase NEPS1; Nepetalactol-related short-chain dehydrogenase; Nepetalactol dehydrogenase; Nepetalactol-related short-chain reductase 1; Nepetalactol-related SDR1; NmNEPS1; EC 5.5.1.34; EC 1.1.1.419 from Nepeta racemosa (Catmint) (Raceme catnip) (see 2 papers)
A0A3Q8GL18 nepetalactol dehydrogenase (EC 1.1.1.419); (+)-cis,trans-nepetalactol synthase (EC 5.5.1.34) from Nepeta racemosa (see 2 papers)
    29% identity, 98% coverage of query (87.4 bits)

5iz4A / Q13GL4 Crystal structure of a putative short-chain dehydrogenase/reductase from burkholderia xenovorans
    30% identity, 93% coverage of query (87.0 bits)

2bgmA X-ray structure of ternary-secoisolariciresinol dehydrogenase
    32% identity, 97% coverage of query (87.0 bits)

2bglA / Q94KL8 X-ray structure of binary-secoisolariciresinol dehydrogenase (see paper)
    32% identity, 97% coverage of query (87.0 bits)

5o6xA 17beta-hydroxysteroid dehydrogenase 14 variant t205 in complex with a non-steroidal quinoline based inhibitor
    29% identity, 80% coverage of query (87.0 bits)

5o43A 17beta-hydroxysteroid dehydrogenase 14 variant t205 in complex with a non-steroidal 2,6-pyridinketone inhibitor.
    29% identity, 80% coverage of query (86.7 bits)

SILD_PODPE / Q94KL8 Secoisolariciresinol dehydrogenase; EC 1.1.1.331 from Podophyllum peltatum (American mandrake) (see 3 papers)
    32% identity, 97% coverage of query (86.7 bits)

5o6oA 17beta-hydroxysteroid dehydrogenase 14 variant t205 in complex with a non-steroidal 2,6-pyridinketone inhibitor
    29% identity, 80% coverage of query (86.7 bits)

5o42A 17beta-hydroxysteroid dehydrogenase 14 variant t205 in complex with a non-steroidal 2,6-pyridinketone inhibitor.
    29% identity, 80% coverage of query (86.7 bits)

5icmA 17beta-hydroxysteroid dehydrogenase type 14 in complex with a non- steroidal inhibitor
    29% identity, 80% coverage of query (86.7 bits)

5l7yA 17beta-hydroxysteroid dehydrogenase 14 variant t205 in complex with a non-steroidal inhibitor.
    29% identity, 80% coverage of query (86.7 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory