Searching for up to 100 curated homologs for RR42_RS28300 FitnessBrowser__Cup4G11:RR42_RS28300 (324 a.a.)
Found high-coverage hits (≥70%) to 51 curated proteins.
Removed hits that are identical to the query, leaving 50
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
E5RQ20 L-threonine 3-dehydrogenase (EC 1.1.1.103) from Cupriavidus necator (see paper)
74% identity, 95% coverage of query (500 bits)
7epsA Partial consensus l-threonine 3-dehydrogenase (e-change) (see paper)
73% identity, 94% coverage of query (492 bits)
7eprB Partial consensus l-threonine 3-dehydrogenase (c-change) (see paper)
70% identity, 94% coverage of query (459 bits)
5z75A Artificial l-threonine 3-dehydrogenase designed by ancestral sequence reconstruction. (see paper)
65% identity, 94% coverage of query (425 bits)
3wmwB / Q0K312 Gale-like l-threonine dehydrogenase from cupriavidus necator (apo form) (see paper)
66% identity, 94% coverage of query (421 bits)
7cgvA Full consensus l-threonine 3-dehydrogenase, fctdh-iiym (NAD+ bound form) (see paper)
61% identity, 94% coverage of query (402 bits)
2yy7A / Q8KZM4 Crystal structure of thermolabile l-threonine dehydrogenase from flavobacterium frigidimaris kuc-1 (see paper)
55% identity, 95% coverage of query (357 bits)
E3PS87 L-threonine 3-dehydrogenase (EC 1.1.1.103) from Acetoanaerobium sticklandii (see paper)
48% identity, 95% coverage of query (321 bits)
6jygD / D0N3N0 Crystal structure of l-threonine dehydrogenase from phytophthora infestans (see paper)
48% identity, 95% coverage of query (308 bits)
3a1nA / Q97BK3 Crystal structure of l-threonine dehydrogenase from hyperthermophilic archaeon thermoplasma volcanium (see paper)
45% identity, 94% coverage of query (308 bits)
Q97BK3 L-threonine 3-dehydrogenase (EC 1.1.1.103) from Thermoplasma volcanium (see paper)
45% identity, 94% coverage of query (308 bits)
3a4vA Crystal structure of pyruvate bound l-threonine dehydrogenase from hyperthermophilic archaeon thermoplasma volcanium
45% identity, 94% coverage of query (308 bits)
3ajrA Crystal structure of l-3-hydroxynorvaline bound l-threonine dehydrogenase (y137f) from hyperthermophilic archaeon thermoplasma volcanium
44% identity, 94% coverage of query (307 bits)
3a9wA Crystal structure of l-threonine bound l-threonine dehydrogenase (y137f) from hyperthermophilic archaeon thermoplasma volcanium
44% identity, 94% coverage of query (307 bits)
D6PBM7 L-threonine 3-dehydrogenase (EC 1.1.1.103) from uncultured archaeon (see paper)
46% identity, 96% coverage of query (302 bits)
5y1fA / D6PBM7 Monomeric l-threonine 3-dehydrogenase from metagenome database (NAD+ bound form) (see paper)
46% identity, 96% coverage of query (302 bits)
5y1eA Monomeric l-threonine 3-dehydrogenase from metagenome database (l-ser and NAD+ bound form)
46% identity, 96% coverage of query (302 bits)
5y1gA Monomeric l-threonine 3-dehydrogenase from metagenome database (akb and nadh bound form)
46% identity, 96% coverage of query (302 bits)
TDH_PIG / Q8MIR0 L-threonine 3-dehydrogenase, mitochondrial; EC 1.1.1.103 from Sus scrofa (Pig) (see paper)
45% identity, 94% coverage of query (261 bits)
TDH_MOUSE / Q8K3F7 L-threonine 3-dehydrogenase, mitochondrial; EC 1.1.1.103 from Mus musculus (Mouse) (see paper)
45% identity, 95% coverage of query (259 bits)
D3ZN15 L-threonine 3-dehydrogenase (EC 1.1.1.103) from Rattus norvegicus (see paper)
44% identity, 94% coverage of query (256 bits)
4yr9A / Q8K3F7 Mouse tdh with NAD+ bound (see paper)
45% identity, 94% coverage of query (253 bits)
Q7YW97 L-threonine 3-dehydrogenase (EC 1.1.1.103) from Trypanosoma brucei (see paper)
41% identity, 96% coverage of query (233 bits)
5k4wC / Q7YW97 Three-dimensional structure of l-threonine 3-dehydrogenase from trypanosoma brucei bound to nadh and l-threonine refined to 1.72 angstroms (see paper)
41% identity, 96% coverage of query (232 bits)
5lc1A L-threonine dehydrogenase from trypanosoma brucei with NAD and the inhibitor pyruvate bound.
41% identity, 96% coverage of query (232 bits)
5k4qA Three-dimensional structure of l-threonine 3-dehydrogenase from trypanosoma brucei bound to NAD+ refined to 2.3 angstroms
41% identity, 96% coverage of query (232 bits)
5k50C Three-dimensional structure of l-threonine 3-dehydrogenase from trypanosoma brucei bound to NAD+ and l-allo-threonine refined to 2.23 angstroms
41% identity, 96% coverage of query (232 bits)
4yrbC / Q8K3F7 Mouse tdh mutant r180k with NAD+ bound (see paper)
36% identity, 94% coverage of query (169 bits)
4yrbB / Q8K3F7 Mouse tdh mutant r180k with NAD+ bound (see paper)
31% identity, 94% coverage of query (126 bits)
Build an alignment for RR42_RS28300 and 29 homologs with ≥ 30% identity
Or download the sequences
DEND_CUPNH / Q0KBD2 D-erythronate dehydrogenase; EC 1.1.1.410 from Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337) (Ralstonia eutropha) (see paper)
Q0KBD2 D-erythronate 2-dehydrogenase (EC 1.1.1.410) from Cupriavidus necator (see paper)
28% identity, 70% coverage of query (73.2 bits)
Q9WYX9 UDP-glucose 4-epimerase (EC 5.1.3.2); UDP-N-acetylglucosamine 4-epimerase (EC 5.1.3.7) from Thermotoga maritima (see paper)
4zrnA / Q9WYX9 Crystal structure of udp-glucose 4-epimerase (tm0509) with udp-glucose from hyperthermophilic eubacterium thermotoga maritima (see paper)
23% identity, 91% coverage of query (69.3 bits)
F2NQX6 UDP-glucose 4-epimerase (EC 5.1.3.2) from Marinithermus hydrothermalis (see paper)
25% identity, 92% coverage of query (67.4 bits)
denD / P44094 D-erythronate 2-dehydrogenase (EC 1.1.1.410) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) (see paper)
DEND_HAEIN / P44094 D-erythronate dehydrogenase; EC 1.1.1.410 from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) (see paper)
24% identity, 87% coverage of query (65.9 bits)
6zllA Crystal structure of udp-glucuronic acid 4-epimerase from bacillus cereus in complex with udp-galacturonic acid and NAD (see paper)
22% identity, 71% coverage of query (57.0 bits)
6zldA Crystal structure of udp-glucuronic acid 4-epimerase from bacillus cereus in complex with udp-glucuronic acid and NAD
22% identity, 71% coverage of query (57.0 bits)
6zl6A Crystal structure of udp-glucuronic acid 4-epimerase from bacillus cereus in complex with udp and NAD
22% identity, 71% coverage of query (57.0 bits)
6zljA Crystal structure of udp-glucuronic acid 4-epimerase y149f mutant from bacillus cereus in complex with udp-4-deoxy-4-fluoro-glucuronic acid and NAD
22% identity, 71% coverage of query (55.5 bits)
8vr2B / Q1QD53 Crystal structure of the pcryo_0617 oxidoreductase/decarboxylase from psychrobacter cryohalolentis k5 in the presence of NAD and udp
25% identity, 84% coverage of query (53.5 bits)
UGA4E_THEGP / F8C4X8 UDP-glucuronate 4-epimerase; UGA4E; TgUGAE; EC 5.1.3.6 from Thermodesulfobacterium geofontis (strain OPF15)
22% identity, 77% coverage of query (53.1 bits)
2ggsA / Q96Z61 Crystal structure of hypothetical dtdp-4-dehydrorhamnose reductase from sulfolobus tokodaii
26% identity, 88% coverage of query (51.2 bits)
1udaA Structure of udp-galactose-4-epimerase complexed with udp-4-deoxy-4- fluoro-alpha-d-galactose
24% identity, 93% coverage of query (50.8 bits)
1naiA Udp-galactose 4-epimerase from escherichia coli, oxidized
24% identity, 93% coverage of query (50.8 bits)
1lrjA Crystal structure of e. Coli udp-galactose 4-epimerase complexed with udp-n-acetylglucosamine
24% identity, 93% coverage of query (50.8 bits)
GalD / b0759 UDP-glucose 4-epimerase (EC 5.1.3.2) from Escherichia coli K-12 substr. MG1655 (see 42 papers)
galE / P09147 UDP-glucose 4-epimerase (EC 5.1.3.2) from Escherichia coli (strain K12) (see 38 papers)
GALE_ECOLI / P09147 UDP-glucose 4-epimerase; Galactowaldenase; UDP-galactose 4-epimerase; EC 5.1.3.2 from Escherichia coli (strain K12) (see 13 papers)
24% identity, 93% coverage of query (50.4 bits)
2udpA Udp-galactose 4-epimerase complexed with udp-phenol
24% identity, 93% coverage of query (50.4 bits)
1udcA Structure of udp-galactose-4-epimerase complexed with udp-mannose
24% identity, 93% coverage of query (50.4 bits)
1kvrA Udp-galactose 4-epimerase complexed with udp-phenol
24% identity, 93% coverage of query (49.3 bits)
GAE6_ARATH / Q9LIS3 UDP-glucuronate 4-epimerase 6; UDP-glucuronic acid epimerase 6; AtUGlcAE2; EC 5.1.3.6 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
Q9LIS3 UDP-glucuronate 4-epimerase (EC 5.1.3.6) from Arabidopsis thaliana (see 3 papers)
23% identity, 75% coverage of query (48.9 bits)
GAE5_ARATH / Q9STI6 UDP-glucuronate 4-epimerase 5; UDP-glucuronic acid epimerase 5; EC 5.1.3.6 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q9STI6 UDP-glucuronate 4-epimerase (EC 5.1.3.6) from Arabidopsis thaliana (see 2 papers)
23% identity, 75% coverage of query (48.9 bits)
1a9yA / P09147 Udp-galactose 4-epimerase mutant s124a/y149f complexed with udp- glucose (see paper)
25% identity, 93% coverage of query (48.1 bits)
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Lawrence Berkeley National Laboratory