Searching for up to 100 curated homologs for RR42_RS29350 FitnessBrowser__Cup4G11:RR42_RS29350 (241 a.a.)
Found high-coverage hits (≥70%) to 18 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
aqpS / Q92R43 aquaglyceroporin from Rhizobium meliloti (strain 1021) (see 2 papers)
AQPS_RHIME / Q92R43 Aquaglyceroporin AqpS from Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti) (see 2 papers)
TC 1.A.8.12.10 / Q92R43 Arsenite export pore, AqpS (see paper)
54% identity, 87% coverage of query (209 bits)
Build an alignment for RR42_RS29350 and 1 homologs with ≥ 30% identity
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AQP10_MILTA / G5CTG7 Aquaporin-10; AQP-10 from Milnesium tardigradum (Water bear) (Tardigrade) (see 2 papers)
26% identity, 96% coverage of query (59.3 bits)
AQP1_RHIO9 / I1CR68 Aquaporin-1 from Rhizopus delemar (strain RA 99-880 / ATCC MYA-4621 / FGSC 9543 / NRRL 43880) (Mucormycosis agent) (Rhizopus arrhizus var. delemar) (see paper)
30% identity, 73% coverage of query (55.5 bits)
AQP2_RHIO9 / I1CS06 Aquaporin-2 from Rhizopus delemar (strain RA 99-880 / ATCC MYA-4621 / FGSC 9543 / NRRL 43880) (Mucormycosis agent) (Rhizopus arrhizus var. delemar) (see paper)
30% identity, 73% coverage of query (55.1 bits)
TC 1.A.8.8.18 / B6ZHB9 Aqp-x2 water channel in the luminal epithelium of urinary bladder cells and lungs from Xenopus laevis
30% identity, 71% coverage of query (53.5 bits)
NIP2-1 / Q6Z2T3 aquaporin NIP2-1 from Oryza sativa subsp. japonica (see 7 papers)
NIP21_ORYSJ / Q6Z2T3 Aquaporin NIP2-1; Low silicon protein 1; NOD26-like intrinsic protein 2-1; OsNIP2;1; Silicon influx transporter LSI1 from Oryza sativa subsp. japonica (Rice) (see 6 papers)
TC 1.A.8.12.2 / Q6Z2T3 The silicon (silicic acid) (undissociated form) transporter, Lsi1 (Ma et al., 2007a, b; Mitani et al., 2008). The barley orthologue Lsi1 (also called NIP2-1) is also a silicon (silicic acid) uptake channel (Chiba et al., 2009). Rice Lsi1 also transports arsenite and pentavalent mono and dimethyl arsenite (Li et al., 2009). In addition to silicon (Si), selenite (Se) uptake is mediated by Lsi1, also called NIP2;1 from Oryza sativa (Rice) (see 6 papers)
NIP2-1 / GI|90855460 aquaporin NIP2-1 from Oryza sativa (japonica cultivar-group) (see paper)
30% identity, 76% coverage of query (51.2 bits)
AQP1_MOUSE / Q02013 Aquaporin-1; AQP-1; Aquaporin-CHIP; Delayed early response protein 2; DER2; Water channel protein for red blood cells and kidney proximal tubule from Mus musculus (Mouse) (see 3 papers)
25% identity, 98% coverage of query (48.9 bits)
AQP3_HUMAN / Q92482 Aquaporin-3; AQP-3; Aquaglyceroporin-3 from Homo sapiens (Human) (see 3 papers)
25% identity, 93% coverage of query (48.1 bits)
AQP3_RAT / P47862 Aquaporin-3; AQP-3; 31.4 kDa water channel protein; Aquaglyceroporin-3 from Rattus norvegicus (Rat) (see 2 papers)
TC 1.A.8.9.1 / P47862 Aquaporin 3. 95% identical to the human orthologue. Poorly permeable to water, but more permeable to glycerol and arsenic trioxide from Rattus norvegicus (Rat) (see 3 papers)
27% identity, 73% coverage of query (47.4 bits)
AQP6_LACBI / I1Z8E8 Aquaporine-6 from Laccaria bicolor (Bicoloured deceiver) (Laccaria laccata var. bicolor) (see 5 papers)
26% identity, 89% coverage of query (47.4 bits)
TC 1.A.8.9.12 / Q6IRR9 Basolateral Aqp3 of 292 aas and 6 TMSs in the frog urinary bladder from Xenopus laevis
25% identity, 95% coverage of query (47.0 bits)
TC 1.A.8.8.15 / B5L019 Mercury-sensitive whitefly aquaporin-1 of the specialized filter chamber of the alimentary tract from Bemisia tabaci
29% identity, 73% coverage of query (47.0 bits)
AQP1_HUMAN / P29972 Aquaporin-1; AQP-1; Aquaporin-CHIP; Urine water channel; Water channel protein for red blood cells and kidney proximal tubule from Homo sapiens (Human) (see 5 papers)
TC 1.A.8.8.1 / P29972 Aquaporin 1 (CO2-, O2- and nitrous oxide-permeable and water-selective) (Zwiazek et al. 2017). Aquaporin-1 tunes pain perception by interacting with Na(v)1.8 Na+ channels in dorsal root ganglion neurons (Zhang and Verkman, 2010). It is upregulated in skeletal muscle in muscular dystrophy (Au et al. 2008). AQP1 has been reported to first insert as a four-helical intermediate, where helices 2 and 4 are not inserted into the membrane. In a second step this intermediate is folded into a six-helical topology. During this process, the orientation of the third helix is inverted, and it can shift out the membrane core from Homo sapiens (Human) (see 19 papers)
25% identity, 95% coverage of query (46.6 bits)
AQP5_MOUSE / Q9WTY4 Aquaporin-5; AQP-5 from Mus musculus (Mouse) (see 7 papers)
27% identity, 77% coverage of query (46.6 bits)
AQP3_PIG / A9Y006 Aquaporin-3; Aquaglyceroporin-3 from Sus scrofa (Pig) (see paper)
27% identity, 73% coverage of query (46.2 bits)
AQP3_MOUSE / Q8R2N1 Aquaporin-3; AQP-3; Aquaglyceroporin-3 from Mus musculus (Mouse) (see 3 papers)
25% identity, 93% coverage of query (46.2 bits)
AQP71_LACBI / I1Z8E9 Aquaporin-7-1 from Laccaria bicolor (Bicoloured deceiver) (Laccaria laccata var. bicolor) (see 4 papers)
29% identity, 72% coverage of query (45.4 bits)
8ct2D / P29972 Local refinement of aqp1 tetramer (c1; refinement mask included d1 of protein 4.2 and ankyrin-1 ar1-5) in class 2 of erythrocyte ankyrin-1 complex (see paper)
25% identity, 93% coverage of query (44.3 bits)
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