Sites on a Tree

 

Searching for up to 100 curated homologs for RR42_RS31980 FitnessBrowser__Cup4G11:RR42_RS31980 (342 a.a.)

Found high-coverage hits (≥70%) to 32 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

ORF17 / Q7WSH4 3-ketosteroid 9α-hydroxylase reductase component (EC 1.14.15.30) from Comamonas testosteroni (see paper)
    52% identity, 99% coverage of query (377 bits)

KSHB_RHORH / B6V6V6 3-ketosteroid-9-alpha-monooxygenase, ferredoxin reductase component; 3-ketosteroid-9-alpha-hydroxylase, ferredoxin reductase component; KSH; Androsta-1,4-diene-3,17-dione 9-alpha-hydroxylase; Rieske-type oxygenase; RO; EC 1.14.15.30 from Rhodococcus rhodochrous (see paper)
    51% identity, 97% coverage of query (342 bits)

Q8KQH9 3-ketosteroid 9alpha-monooxygenase (EC 1.14.15.30) from Rhodococcus erythropolis (see paper)
    50% identity, 94% coverage of query (325 bits)

kshB / P9WJ93 NADH-ferredoxin reductase (EC 1.18.1.3) from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
KSHB_MYCTU / P9WJ93 3-ketosteroid-9-alpha-monooxygenase, ferredoxin reductase component; 3-ketosteroid-9-alpha-hydroxylase, ferredoxin reductase component; KSH; Androsta-1,4-diene-3,17-dione 9-alpha-hydroxylase; Rieske-type oxygenase; RO; EC 1.14.15.30 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 3 papers)
P9WJ93 3-ketosteroid 9alpha-monooxygenase (EC 1.14.15.30) from Mycobacterium tuberculosis (see paper)
    50% identity, 97% coverage of query (311 bits)

F1CMX3 3-ketosteroid 9alpha-monooxygenase (EC 1.14.15.30) from Rhodococcus rhodochrous (see 2 papers)
    48% identity, 97% coverage of query (310 bits)

D2Y640 3-ketosteroid 9alpha-monooxygenase (subunit 1/2) (EC 1.14.15.30) from Mycolicibacterium neoaurum (see paper)
    47% identity, 97% coverage of query (279 bits)

tdnB / BAC82528.1 reductase component in aniline dioxygenase from Frateuria sp. ANA-18 (see 3 papers)
    41% identity, 98% coverage of query (249 bits)

atdA5 / Q44253 N-glutamylanilide dioxygenase ferredoxin reductase component from Acinetobacter sp. YAA (see paper)
    37% identity, 97% coverage of query (226 bits)

YdbR / b1392 phenylacetyl-CoA 1,2-epoxidase, reductase subunit (EC 1.14.13.149) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
paaE / P76081 phenylacetyl-CoA 1,2-epoxidase, reductase subunit (EC 1.14.13.149) from Escherichia coli (strain K12) (see 2 papers)
PAAE_ECOLI / P76081 1,2-phenylacetyl-CoA epoxidase, subunit E; 1,2-phenylacetyl-CoA epoxidase, reductase subunit; 1,2-phenylacetyl-CoA monooxygenase, subunit E; EC 1.-.-.- from Escherichia coli (strain K12) (see 5 papers)
    34% identity, 98% coverage of query (194 bits)

paaE / Q845J2 ring 1,2-phenylacetyl-CoA epoxidase PaaE subunit (EC 1.14.13.149) from Pseudomonas sp. Y2 (see paper)
    35% identity, 99% coverage of query (186 bits)

gbcB / Q9HTF3 glycine betaine monooxygenase ferredoxin reductase subunit (EC 1.14.13.251) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 5 papers)
GBMOR_PSEAB / A0A0H2ZJB2 Glycine betaine monooxygenase reductase subunit; Glycine betaine catabolism B; EC 1.14.13.251 from Pseudomonas aeruginosa (strain UCBPP-PA14) (see paper)
GBMOR_PSEAE / Q9HTF3 Glycine betaine monooxygenase reductase subunit; Glycine betaine catabolism B; EC 1.14.13.251 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
    31% identity, 94% coverage of query (157 bits)

GBMOR_CHRSD / Q1QYU6 Glycine betaine monooxygenase reductase subunit; BMO reductase subunit; GB monooxygenase reductase subunit; BMO NADH-dependent flavine reductase component; EC 1.14.13.251 from Chromohalobacter salexigens (strain ATCC BAA-138 / DSM 3043 / CIP 106854 / NCIMB 13768 / 1H11) (see paper)
    30% identity, 94% coverage of query (151 bits)

antL / A3KI24 anthraniloyl-[acp] 1,2-epoxidase subunit L from Streptomyces ambofaciens (strain ATCC 23877 / 3486 / DSM 40053 / JCM 4204 / NBRC 12836 / NRRL B-2516) (see 2 papers)
    33% identity, 94% coverage of query (147 bits)

stc4 / Q92ZP8 stachydrine N-demethylase reductase subunit (EC 1.14.13.247) from Rhizobium meliloti (strain 1021) (see paper)
    32% identity, 93% coverage of query (135 bits)

Build an alignment

Build an alignment for RR42_RS31980 and 14 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

YbjV / b0872 NADH oxidoreductase from Escherichia coli K-12 substr. MG1655 (see paper)
hcr / P75824 NADH oxidoreductase from Escherichia coli (strain K12) (see paper)
    27% identity, 88% coverage of query (103 bits)

2piaA / P33164 Phthalate dioxygenase reductase: a modular structure for electron transfer from pyridine nucleotides to [2fe-2s] (see paper)
    30% identity, 88% coverage of query (96.7 bits)

PDR_BURCE / P33164 Phthalate dioxygenase reductase; PDR; EC 1.-.-.- from Burkholderia cepacia (Pseudomonas cepacia) (see paper)
ophA1 / GB|AAD03550.1 phthalate dioxygenase reductase; EC 1.-.-.- from Burkholderia cepacia (see 2 papers)
    30% identity, 88% coverage of query (96.7 bits)

P9WNE9 stearoyl-CoA 9-desaturase electron-transfer subunit from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 3 papers)
DESET_MYCTU / P9WNE9 NADPH oxidoreductase; Stearoyl-CoA 9-desaturase electron transfer partner; EC 1.-.-.- from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
    28% identity, 87% coverage of query (95.1 bits)

ndmD / H9N291 FMN reductase [NAD(P)H] (EC 1.5.1.39) from Pseudomonas putida (see 2 papers)
NDMD_PSEPU / H9N291 Oxidoreductase NdmD; EC 1.-.-.- from Pseudomonas putida (Arthrobacter siderocapsulatus) (see 2 papers)
    29% identity, 89% coverage of query (92.4 bits)

6laaA / A0A0K6ITW2 Crystal structure of full-length cyp116b46 from tepidiphilus thermophilus (see paper)
    28% identity, 84% coverage of query (90.5 bits)

6kbhA / C7SFP5 Crystal structure of an intact type iv self-sufficient cytochrome p450 monooxygenase
    30% identity, 86% coverage of query (90.1 bits)

7ylrA / C5CSP5 Structure of a bacteria protein
    29% identity, 88% coverage of query (87.4 bits)

iphD / BAH70272.1 reductase component of isophthalate dioxygenase from Comamonas sp. E6 (see 2 papers)
    31% identity, 72% coverage of query (87.0 bits)

Q2KQ78 vanillate monooxygenase (EC 1.14.13.82) from Comamonas testosteroni (see paper)
ivaB / AAW33717.1 IvaB from Comamonas testosteroni (see paper)
    28% identity, 83% coverage of query (86.3 bits)

tsaB / P94680 4-toluene-sulfonate monooxygenase reductase subunit from Comamonas testosteroni (see paper)
TSAB1_COMTE / P94680 Toluene-4-sulfonate monooxygenase system reductase subunit TsaB1; TS methylmonooxygenase system, reductase B; Toluenesulfonate methyl-monooxygenase reductase component TsaB1; EC 1.5.1.- from Comamonas testosteroni (Pseudomonas testosteroni) (see paper)
    31% identity, 92% coverage of query (86.3 bits)

yeaX / F0KFI7 carnitine monooxygenase β subunit (EC 1.14.13.239) from Acinetobacter calcoaceticus (strain PHEA-2) (see 2 papers)
CNTB_ACICP / F0KFI7 Carnitine monooxygenase reductase subunit; Carnitine monooxygenase beta subunit; EC 1.14.13.239 from Acinetobacter calcoaceticus (strain PHEA-2) (see paper)
    26% identity, 82% coverage of query (85.9 bits)

cntB / D0C9N8 carnitine monooxygenase reductase component (EC 1.14.13.239) from Acinetobacter baumannii (strain ATCC 19606 / DSM 30007 / JCM 6841 / CCUG 19606 / CIP 70.34 / NBRC 109757 / NCIMB 12457 / NCTC 12156 / 81) (see paper)
CNTB_ACIB2 / D0C9N8 Carnitine monooxygenase reductase subunit; Carnitine monooxygenase beta subunit; EC 1.14.13.239 from Acinetobacter baumannii (strain ATCC 19606 / DSM 30007 / JCM 6841 / CCUG 19606 / CIP 70.34 / NBRC 109757 / NCIMB 12457 / NCTC 12156 / 81) (see paper)
D0C9N8 carnitine monooxygenase (subunit 1/2) (EC 1.14.13.239) from Acinetobacter baumannii (see paper)
    27% identity, 82% coverage of query (85.5 bits)

M9WIZ7 tetrachlorobenzoquinone reductase (EC 1.1.1.404) from Sphingobium chlorophenolicum (see paper)
    28% identity, 82% coverage of query (82.8 bits)

Q8FRX3 vanillate monooxygenase (subunit 1/2) (EC 1.14.13.82) from Corynebacterium efficiens (see paper)
    25% identity, 96% coverage of query (81.6 bits)

PCPD_SPHCR / Q47914 Tetrachlorobenzoquinone reductase; TCBQ reductase; EC 1.1.1.404 from Sphingobium chlorophenolicum (see 2 papers)
Q47914 tetrachlorobenzoquinone reductase (EC 1.1.1.404) from Sphingobium chlorophenolicum (see paper)
    28% identity, 82% coverage of query (80.9 bits)

pcpD / A0A081RAW0 tetrachlorobenzoquinone reductase monomer (EC 1.1.1.404) from Sphingobium chlorophenolicum (see 2 papers)
    28% identity, 82% coverage of query (80.1 bits)

M9WLE1 tetrachlorobenzoquinone reductase (EC 1.1.1.404) from Sphingobium chlorophenolicum (see 3 papers)
    28% identity, 82% coverage of query (80.1 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory