Searching for up to 100 curated homologs for RR42_RS32055 FitnessBrowser__Cup4G11:RR42_RS32055 (442 a.a.)
Found high-coverage hits (≥70%) to 37 curated proteins.
Removed hits that are identical to the query, leaving 36
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
pcaB / AAC37149.1 beta-carboxy-cis,cis-muconate cycloisomerase from Acinetobacter baylyi (see 11 papers)
48% identity, 99% coverage of query (392 bits)
YBN5_SCHPO / O42889 Uncharacterized protein C8E4.05c from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
40% identity, 99% coverage of query (316 bits)
TAD1 / A0A0U2UYC4 trans-aconitate decarboxylase (EC 4.1.1.113) from Ustilago maydis (see paper)
TAD1_USTMD / A0A0U2UYC4 Trans-aconitate decarboxylase 1; Itaconic acid/2-hydroxyparaconate biosynthesis cluster protein TAD1; EC 4.1.1.113 from Ustilago maydis (Corn smut fungus) (see 2 papers)
A0A0U2UYC4 trans-aconitate decarboxylase (EC 4.1.1.113) from Ustilago maydis (see paper)
41% identity, 99% coverage of query (312 bits)
pcaB2 / Q2HNY9 3-carboxymuconate lactonizing enzyme type 2 (EC 5.5.1.2) from Hydrogenophaga intermedia (see 2 papers)
42% identity, 90% coverage of query (293 bits)
2SL_DICD3 / E0SKP1 N-acetyl-S-(2-succino)cysteine lyase; S-(2-succino) lyase; 2SL; EC 4.3.2.- from Dickeya dadantii (strain 3937) (Erwinia chrysanthemi (strain 3937)) (see paper)
37% identity, 99% coverage of query (276 bits)
2SL_ENTI1 / E6LDH5 N-acetyl-S-(2-succino)cysteine lyase; S-(2-succino) lyase; 2SL; EC 4.3.2.- from Enterococcus italicus (strain DSM 15952 / CCUG 50447 / LMG 22039 / TP 1.5) (see paper)
38% identity, 100% coverage of query (265 bits)
creD / A0A0K2JL82 nitrosuccinate lyase (EC 4.3.99.5) from Streptomyces cremeus (see paper)
CRED_STRCM / A0A0K2JL82 Nitrosuccinate lyase; EC 4.3.99.5 from Streptomyces cremeus (see 3 papers)
A0A0K2JL82 nitrosuccinate lyase (EC 4.3.99.5) from Streptomyces cremeus (see paper)
45% identity, 98% coverage of query (257 bits)
CREDH_STRDJ / K4R6W4 Nitrosuccinate lyase; EC 4.3.99.5 from Streptomyces davaonensis (strain DSM 101723 / JCM 4913 / KCC S-0913 / 768) (see paper)
43% identity, 97% coverage of query (255 bits)
5xnzA / A0A0K2JL82 Crystal structure of cred complex with fumarate (see paper)
44% identity, 98% coverage of query (244 bits)
MJ0929 / Q58339 adenylosuccinate lyase (EC 4.3.2.2) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (see 2 papers)
30% identity, 100% coverage of query (201 bits)
Q2HNZ1 3-Carboxy-cis,cis-muconate cycloisomerase (EC 5.5.1.2) from Agrobacterium tumefaciens (see paper)
40% identity, 73% coverage of query (200 bits)
pcaB / AAF34266.1 3-carboxy-cis,cis-muconate cycloisomerase from Agrobacterium tumefaciens (see 2 papers)
39% identity, 73% coverage of query (185 bits)
Build an alignment for RR42_RS32055 and 12 homologs with ≥ 30% identity
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PUR8_THEMA / Q9X0I0 Adenylosuccinate lyase; ASL; Adenylosuccinase; ASase; EC 4.3.2.2 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
28% identity, 94% coverage of query (165 bits)
PUR8_STAAW / Q7A0G9 Adenylosuccinate lyase; ASL; Adenylosuccinase; ASase; EC 4.3.2.2 from Staphylococcus aureus (strain MW2) (see paper)
Q7A0G9 adenylosuccinate lyase (EC 4.3.2.2) from Staphylococcus aureus (see paper)
29% identity, 82% coverage of query (160 bits)
toyF / B6CWI9 succinylo-toyocamycin phosphate lyase from Streptomyces rimosus (see paper)
36% identity, 90% coverage of query (158 bits)
2x75A / Q7A0G9 Staphylococcus aureus adenylosuccinate lyase (see paper)
28% identity, 82% coverage of query (156 bits)
PUR8_BACSU / P12047 Adenylosuccinate lyase; ASL; Adenylosuccinase; ASase; Glutamyl--tRNA ligase regulatory factor; EC 4.3.2.2 from Bacillus subtilis (strain 168) (see 2 papers)
P12047 adenylosuccinate lyase (EC 4.3.2.2) from Bacillus subtilis (see paper)
purB / GI|143366 (glutamyl-trna synthetase regulatory factor); EC 4.3.2.2 from Bacillus subtilis (see 4 papers)
29% identity, 81% coverage of query (144 bits)
Q8ZY28 adenylosuccinate lyase (EC 4.3.2.2) from Pyrobaculum aerophilum (see paper)
29% identity, 82% coverage of query (110 bits)
ade13 / Q05911 Ade13 (EC 4.3.2.2) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see paper)
25% identity, 79% coverage of query (82.4 bits)
Q05911 Adenylosuccinate lyase; ASL; Adenylosuccinase; ASase; EC 4.3.2.2 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
25% identity, 79% coverage of query (82.4 bits)
ADE13 enzyme of adenine biosynthesis from Candida albicans (see paper)
27% identity, 78% coverage of query (79.3 bits)
PUR8_CHICK / P21265 Adenylosuccinate lyase; ADSL; ASL; Adenylosuccinase; ASase; EC 4.3.2.2 from Gallus gallus (Chicken) (see paper)
27% identity, 78% coverage of query (72.0 bits)
B2LS18 adenylosuccinate lyase (EC 4.3.2.2) from Ctenopharyngodon idella (see paper)
26% identity, 99% coverage of query (70.5 bits)
5vkwB / A0A1D8PT56 Crystal structure of adenylosuccinate lyase ade13 from candida albicans
26% identity, 78% coverage of query (68.6 bits)
ADSL / P30566 adenylosuccinate lyase (EC 4.3.2.2) from Homo sapiens (see 3 papers)
PUR8_HUMAN / P30566 Adenylosuccinate lyase; ADSL; ASL; Adenylosuccinase; ASase; EC 4.3.2.2 from Homo sapiens (Human) (see 14 papers)
P30566 adenylosuccinate lyase (EC 4.3.2.2) from Homo sapiens (see 5 papers)
26% identity, 80% coverage of query (67.4 bits)
5nx9D / A0A384E0N4 Crystal structure of neanderthal adenylosuccinate lyase (adsl) in complex with its products amp and fumarate (see paper)
26% identity, 80% coverage of query (67.4 bits)
5eytA / G4VQX9 Crystal structure of adenylosuccinate lyase from schistosoma mansoni in complex with amp (see paper)
24% identity, 80% coverage of query (67.0 bits)
FUMC_SACS2 / P39461 Fumarate hydratase class II; Fumarase C; Aerobic fumarase; Iron-independent fumarase; EC 4.2.1.2 from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see 2 papers)
P39461 fumarate hydratase (EC 4.2.1.2) from Saccharolobus solfataricus (see paper)
25% identity, 74% coverage of query (66.6 bits)
5nxaB Crystal structure of neanderthal adenylosuccinate lyase (adsl)in complex with its products aicar and fumarate
25% identity, 78% coverage of query (62.8 bits)
FUMH_YEAST / P08417 Fumarate hydratase, mitochondrial; Fumarase; EC 4.2.1.2 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 7 papers)
P08417 fumarate hydratase (EC 4.2.1.2) from Saccharomyces cerevisiae (see 2 papers)
23% identity, 80% coverage of query (57.8 bits)
7c18B / Q65UJ3 Crystal structure of fumarasec from mannheimia succiniciproducens in complex with fumarate
26% identity, 76% coverage of query (53.5 bits)
6g3hA Crystal structure of edds lyase in complex with ss-edds
26% identity, 71% coverage of query (50.4 bits)
6g3gA Crystal structure of edds lyase in complex with succinate
26% identity, 71% coverage of query (50.4 bits)
6g3fA / Q11KV9 Crystal structure of edds lyase in complex with fumarate (see paper)
26% identity, 71% coverage of query (50.4 bits)
6g3iA Crystal structure of edds lyase in complex with n-(2-aminoethyl) aspartic acid (aeaa)
26% identity, 71% coverage of query (50.4 bits)
2e9fB / Q5SLL0 Crystal structure of t.Th.Hb8 argininosuccinate lyase complexed with l-arginine
27% identity, 74% coverage of query (45.1 bits)
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