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Searching for up to 100 curated homologs for RR42_RS32635 FitnessBrowser__Cup4G11:RR42_RS32635 (63 a.a.)

Found high-coverage hits (≥70%) to 14 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

P49172 2-hydroxymuconate tautomerase (EC 5.3.2.6) from Pseudomonas sp. (see paper)
dmpI / CAA43229.1 4-oxalocrotonate from Pseudomonas sp. CF600 (see paper)
    51% identity, 100% coverage of query (72.0 bits)

nahJ / BAE92174.1 4-oxalocrotonate tautomerase NahJ from Pseudomonas putida (see 2 papers)
    49% identity, 100% coverage of query (72.0 bits)

cnbG / Q38M36 2-hydroxymuconate tautomerase (EC 5.3.2.6) from Comamonas testosteroni CNB-1 (see paper)
    46% identity, 100% coverage of query (64.7 bits)

xylH / Q01468 4-oxalocrotonate tautomerase subunit (EC 5.3.2.6) from Pseudomonas putida (see 4 papers)
4OT1_PSEPU / Q01468 2-hydroxymuconate tautomerase; 4-oxalocrotonate tautomerase; 4-OT; EC 5.3.2.6 from Pseudomonas putida (Arthrobacter siderocapsulatus) (see 2 papers)
Q01468 2-hydroxymuconate tautomerase (EC 5.3.2.6) from Pseudomonas putida (see 3 papers)
xylH / AAA25694.1 4-oxalocrotonate tautomerase from Pseudomonas putida (see paper)
    46% identity, 100% coverage of query (62.8 bits)

1bjpA / Q01468 Crystal structure of 4-oxalocrotonate tautomerase inactivated by 2- oxo-3-pentynoate at 2.4 angstroms resolution (see paper)
    45% identity, 98% coverage of query (60.5 bits)

5tigA Crystal structure of 4-oxalocrotonate tautomerase inactivated by brhpd
    45% identity, 98% coverage of query (60.5 bits)

6bgnA Crystal structure of 4-oxalocrotonate tautomerase after incubation with 5-fluoro-2-hydroxy-2,4-pentadienoate
    46% identity, 94% coverage of query (58.9 bits)

6ghwC Substituting the prolines of 4-oxalocrotonate tautomerase with non- canonical analogue (2s)-3,4-dehydroproline
    47% identity, 90% coverage of query (58.9 bits)

praC / C4TP07 4-oxalocrotonate tautomerase (EC 5.3.2.6) from Paenibacillus sp. JJ-1b (see paper)
C4TP07 2-hydroxymuconate tautomerase (EC 5.3.2.6) from Paenibacillus sp. (see paper)
praC / BAH79105.1 4-oxalocrotonate tautomerase from Paenibacillus sp. JJ-1b (see paper)
    43% identity, 95% coverage of query (58.5 bits)

5cloM Crystal structure of a 4-oxalocrotonate tautomerase mutant in complex with nitrostyrene at 2.3 angstrom
    46% identity, 90% coverage of query (55.1 bits)

A2SL37 2-hydroxymuconate tautomerase (EC 5.3.2.6) from Methylibium petroleiphilum (see paper)
    40% identity, 90% coverage of query (49.3 bits)

ywhB / P70994 4-oxalocrotonate tautomerase homolog (EC 5.3.2.1) from Bacillus subtilis (strain 168) (see 5 papers)
4OT_BACSU / P70994 2-hydroxymuconate tautomerase; (2Z,4E)-2-hydroxyhexa-2,4-dienedioate keto-enol isomerase; 4-oxalocrotonate tautomerase; 4-OT; EC 5.3.2.6 from Bacillus subtilis (strain 168) (see paper)
    39% identity, 89% coverage of query (48.9 bits)

Q6GH41 2-hydroxymuconate tautomerase (EC 5.3.2.6) from Staphylococcus aureus (see paper)
    38% identity, 87% coverage of query (48.5 bits)

2opaA / P70994 Ywhb binary complex with 2-fluoro-p-hydroxycinnamate
    38% identity, 87% coverage of query (47.0 bits)

Build an alignment

Build an alignment for RR42_RS32635 and 14 homologs with ≥ 30% identity

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory