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Searching for up to 100 curated homologs for RR42_RS34085 FitnessBrowser__Cup4G11:RR42_RS34085 (210 a.a.)

Found high-coverage hits (≥70%) to 83 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

YfcF / b2301 glutathione S-transferase YfcF (EC 2.5.1.18) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
yfcF / P77544 glutathione S-transferase YfcF (EC 2.5.1.18) from Escherichia coli (strain K12) (see 2 papers)
YFCF_ECOLI / P77544 Glutathione S-transferase YfcF; EC 2.5.1.18 from Escherichia coli (strain K12) (see paper)
    58% identity, 98% coverage of query (231 bits)

4jbbA / A6TBY7 Crystal structure of glutathione s-transferase a6tby7(target efi- 507184) from klebsiella pneumoniae mgh 78578, gsh complex
    59% identity, 96% coverage of query (226 bits)

3bbyA / P77544 Crystal structure of glutathione s-transferase (np_416804.1) from escherichia coli k12 at 1.85 a resolution
    57% identity, 96% coverage of query (214 bits)

4isdA / C5A7Z5 Crystal structure of glutathione transferase homolog from burkholderia gl bgr1, target efi-501803, with bound glutathione
    49% identity, 96% coverage of query (183 bits)

4hojA / O33374 Crystal structure of glutathione transferase homolog from neisseria gonorrhoeae, target efi-501841, with bound glutathione
    32% identity, 87% coverage of query (70.5 bits)

4qq7A / B4E6Q3 Crystal structure of putative stringent starvation protein a from burkholderia cenocepacia with bound glutathione
    30% identity, 87% coverage of query (65.9 bits)

A0A4Y5QZX2 glutathione transferase (EC 2.5.1.18) from Salix babylonica (see paper)
    30% identity, 75% coverage of query (63.2 bits)

Build an alignment

Build an alignment for RR42_RS34085 and 7 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

7zvpA Crystal structure of poplar glutathione transferase u19 in complex with glutathione
    29% identity, 74% coverage of query (62.0 bits)

7dweA / A0A4Y5R087 Crystal structure of a glutathione s-transferase sbgstu7 from salix babylonica in complex with glutathione
    28% identity, 71% coverage of query (60.8 bits)

A0A4Y5R087 glutathione transferase (EC 2.5.1.18) from Salix babylonica (see paper)
    28% identity, 72% coverage of query (60.8 bits)

A0A4Y5QZW9 glutathione transferase (EC 2.5.1.18) from Salix babylonica (see paper)
    28% identity, 75% coverage of query (60.1 bits)

A0A4Y5R0C1 glutathione transferase (EC 2.5.1.18) from Salix babylonica (see paper)
    29% identity, 74% coverage of query (59.3 bits)

8a0pA / D2X9R3 Crystal structure of poplar glutathione transferase u20 in complex with morin (see paper)
    28% identity, 73% coverage of query (58.5 bits)

8a0rA Crystal structure of poplar glutathione transferase u20 in complex with pinocembrin
    28% identity, 73% coverage of query (58.5 bits)

8a0qA Crystal structure of poplar glutathione transferase u20 in complex with baicalein
    28% identity, 73% coverage of query (58.5 bits)

8a0oA Crystal structure of poplar glutathione transferase u20 in complex with galangin
    28% identity, 73% coverage of query (58.5 bits)

8a0iA Crystal structure of poplar glutathione transferase u20 in complex with glutathionylphenylacetophenone
    28% identity, 73% coverage of query (58.5 bits)

8a08A Crystal structure of poplar glutathione transferase u20 in complex with glutathione
    28% identity, 73% coverage of query (58.5 bits)

D2WL57 glutathione transferase (EC 2.5.1.18) from Populus trichocarpa (see paper)
    25% identity, 70% coverage of query (57.8 bits)

6gibB / A0A452CSY5 Crystal structure of glutathione transferase omega 2s from trametes versicolor
    28% identity, 82% coverage of query (57.4 bits)

6gicB Crystal structure of glutathione transferase omega 2s from trametes versicolor in complex with oxyresveratrol
    28% identity, 82% coverage of query (57.4 bits)

GSTZ1_ARATH / Q9ZVQ3 Glutathione S-transferase Z1; AtGSTZ1; GST class-zeta member 1; Glutathione S-transferase 18; Maleylacetone isomerase; MAI; EC 2.5.1.18; EC 5.2.1.- from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    28% identity, 70% coverage of query (57.0 bits)

Q8DMB4 glutathione transferase (EC 2.5.1.18) from Thermosynechococcus vestitus (see paper)
    30% identity, 84% coverage of query (56.6 bits)

GSTO1_PIG / Q9N1F5 Glutathione S-transferase omega-1; GSTO-1; Glutathione S-transferase omega 1-1; GSTO 1-1; Glutathione-dependent dehydroascorbate reductase; Monomethylarsonic acid reductase; MMA(V) reductase; S-(Phenacyl)glutathione reductase; SPG-R; EC 2.5.1.18; EC 1.8.5.1; EC 1.20.4.2 from Sus scrofa (Pig) (see paper)
    28% identity, 80% coverage of query (54.3 bits)

desD / Q2G4C2 4-carboxy-2-hydroxyhexa-2,4-dienedioate cis-trans isomerase from Novosphingobium aromaticivorans (strain ATCC 700278 / DSM 12444 / CCUG 56034 / CIP 105152 / NBRC 16084 / F199) (see paper)
    24% identity, 81% coverage of query (53.9 bits)

GSTL2_ARATH / Q9M2W2 Glutathione S-transferase L2, chloroplastic; AtGSTL2; GST class-lambda member 2; EC 2.5.1.18 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
    28% identity, 85% coverage of query (53.5 bits)

A0A4Y5QZX0 glutathione transferase (EC 2.5.1.18) from Salix babylonica (see paper)
    26% identity, 91% coverage of query (53.5 bits)

6ht6A Crystal structure of glutathione transferase omega 2s from trametes versicolor in complex with 2,4-dihydroxybenzophenone
    28% identity, 82% coverage of query (53.5 bits)

6gicA Crystal structure of glutathione transferase omega 2s from trametes versicolor in complex with oxyresveratrol
    28% identity, 82% coverage of query (53.5 bits)

GSTT3_MOUSE / Q99L20 Glutathione S-transferase theta-3; EC 2.5.1.18 from Mus musculus (Mouse) (see paper)
    29% identity, 70% coverage of query (52.8 bits)

Q9FQE8 glutathione transferase (EC 2.5.1.18) from Glycine max (see paper)
    30% identity, 74% coverage of query (52.0 bits)

4chsA Crystal structure of a tau class glutathione transferase 10 from glycine max
    30% identity, 74% coverage of query (52.0 bits)

8ax1A Crystal structure of trametes versicolor glutathione transferase omega 3s in complex with hydroxy-tetranitro-nitrosyl-ruthenate
    27% identity, 76% coverage of query (51.6 bits)

6f51A Crystal structure of glutathione transferase omega 3s from trametes versicolor in complex with glutathionyl-phenylacetophenone
    27% identity, 76% coverage of query (51.6 bits)

4is0A Structural insights into omega-class glutathione transferases: a snapshot of enzyme reduction and identification of the non-catalytic ligandin site.
    27% identity, 80% coverage of query (51.6 bits)

8ax0A Crystal structure of trametes versicolor glutathione transferase omega 3s in complex with sodium nitroprusside
    27% identity, 76% coverage of query (51.2 bits)

8awzA / A0A384E145 Crystal structure of trametes versicolor glutathione transferase omega 3s in complex with dinitrosyl glutathionyl iron complex (dngic) (see paper)
    27% identity, 76% coverage of query (51.2 bits)

6hpeA Crystal structure of glutathione transferase omega 3s from trametes versicolor in complex with the glutathione adduct of phenethyl- isothiocyanate
    27% identity, 76% coverage of query (51.2 bits)

6f6aA Crystal structure of glutathione transferase omega 3s from trametes versicolor in complex with dihydrowogonin from wild-cherry extract
    27% identity, 76% coverage of query (51.2 bits)

6f69A Crystal structure of glutathione transferase omega 3s from trametes versicolor in complex with 2,3,4-trihydroxybenzophenone
    27% identity, 76% coverage of query (51.2 bits)

6f68A Crystal structure glutathione transferase omega 3s from trametes versicolor in complex with 2,4,4'-trihydroxybenzophenone
    27% identity, 76% coverage of query (51.2 bits)

6f67A Crystal structure of glutathione transferase omega 3s from trametes versicolor in complex with 3,4-dihydroxybenzophenone
    27% identity, 76% coverage of query (51.2 bits)

6f66A Crystal structure of glutathione transferase omega 3s from trametes versicolor in complex with 2,4-dihydroxybenzophenone
    27% identity, 76% coverage of query (51.2 bits)

6f4kA Crystal structure of glutathione transferase omega 3s from trametes versicolor in complex with hexyl-glutathione
    27% identity, 76% coverage of query (51.2 bits)

6f4fA Crystal structure of glutathione transferase omega 3s from trametes versicolor in complex with glutathionyl-s-dinitrobenzene
    27% identity, 76% coverage of query (51.2 bits)

GSTO2_HUMAN / Q9H4Y5 Glutathione S-transferase omega-2; GSTO-2; Glutathione S-transferase omega 2-2; GSTO 2-2; Glutathione-dependent dehydroascorbate reductase; Monomethylarsonic acid reductase; MMA(V) reductase; EC 2.5.1.18; EC 1.8.5.1; EC 1.20.4.2 from Homo sapiens (Human) (see 3 papers)
Q9H4Y5 glutathione dehydrogenase (ascorbate) (EC 1.8.5.1); glutathione transferase (EC 2.5.1.18) from Homo sapiens (see 3 papers)
    27% identity, 81% coverage of query (51.2 bits)

3vlnA Human glutathione transferase o1-1 c32s mutant in complex with ascorbic acid
    27% identity, 80% coverage of query (51.2 bits)

2cz2A / Q9WVL0 Crystal structure of glutathione transferase zeta 1-1 (maleylacetoacetate isomerase) from mus musculus (form-1 crystal)
    27% identity, 72% coverage of query (50.1 bits)

Q9WVL0 Maleylacetoacetate isomerase; MAAI; GSTZ1-1; Glutathione S-transferase zeta 1; EC 5.2.1.2; EC 2.5.1.18 from Mus musculus (Mouse)
    27% identity, 72% coverage of query (50.1 bits)

6pnoA Human gsto1-1 complexed with 2-chloro-n-(4-chloro-3-(n- isopropylsulfamoyl)phenyl)acetamide
    27% identity, 80% coverage of query (50.1 bits)

6pnmA Human gsto1-1 complexed with 2-chloro-n-(4-chloro-3- (morpholinosulfonyl)phenyl)acetamide
    27% identity, 80% coverage of query (50.1 bits)

5v3qA Human gsto1-1 complexed with ml175
    27% identity, 80% coverage of query (50.1 bits)

5uehA Structure of gsto1 covalently conjugated to quinolinic acid fluorosulfate
    27% identity, 80% coverage of query (50.1 bits)

6pnnA Human gsto1-1 complexed with 2-chloro-n-(4-chloro-3-(n-(2- methoxyethyl)-n-methylsulfamoyl)phenyl)acetamide
    27% identity, 80% coverage of query (50.1 bits)

4yqvA Glutathione s-transferase omega 1 bound to covalent inhibitor c4-10
    27% identity, 80% coverage of query (50.1 bits)

4yqmA Glutathione s-transferase omega 1 bound to covalent inhibitor c1-27
    27% identity, 80% coverage of query (50.1 bits)

1eemA Glutathione transferase from homo sapiens
    27% identity, 80% coverage of query (50.1 bits)

GSTO1 / P78417 glutathione transferase, Ω class subunit (EC 2.5.1.18; EC 1.8.5.1; EC 1.20.4.2) from Homo sapiens (see 2 papers)
GSTO1_HUMAN / P78417 Glutathione S-transferase omega-1; GSTO-1; Glutathione S-transferase omega 1-1; GSTO 1-1; Glutathione-dependent dehydroascorbate reductase; Monomethylarsonic acid reductase; MMA(V) reductase; S-(Phenacyl)glutathione reductase; SPG-R; EC 2.5.1.18; EC 1.8.5.1; EC 1.20.4.2 from Homo sapiens (Human) (see 5 papers)
P78417 methylarsonate reductase (EC 1.20.4.2); glutathione dehydrogenase (ascorbate) (EC 1.8.5.1); glutathione transferase (EC 2.5.1.18) from Homo sapiens (see 7 papers)
    27% identity, 80% coverage of query (50.1 bits)

5g5aA / Q9SHH7 Glutathione transferase u25 from arabidopsis thaliana in complex with glutathione disulfide
    28% identity, 74% coverage of query (50.1 bits)

6mhdA Glutathione s-transferase omega 1 bound to covalent inhibitor 44
    27% identity, 80% coverage of query (49.7 bits)

6mhcA / P78417 Glutathione s-transferase omega 1 bound to covalent inhibitor 37 (see paper)
    27% identity, 80% coverage of query (49.7 bits)

5g5fA Crystallographic structure of the tau class glutathione s-transferase migstu in complex with reduced glutathione.
    28% identity, 74% coverage of query (49.3 bits)

5kejA / A0A1P8NWC2 Crystallographic structure of the tau class glutathione s-transferase migstu in complex with s-hexyl-glutathione (see paper)
    28% identity, 74% coverage of query (49.3 bits)

4pqhA / B9HM14 Crystal structure of glutathione transferase lambda1 from populus trichocarpa (see paper)
    26% identity, 80% coverage of query (48.9 bits)

3pr8A / Q88RE7 Structure of glutathione s-transferase(pp0183) from pseudomonas putida in complex with gsh
    29% identity, 88% coverage of query (48.1 bits)

1fw1A / O43708 Glutathione transferase zeta/maleylacetoacetate isomerase (see paper)
    26% identity, 75% coverage of query (47.8 bits)

GSTZ1 / O43708 maleylacetoacetate isomerase/glutathione transferase ζ monomer (EC 2.5.1.18; EC 5.2.1.2) from Homo sapiens (see 11 papers)
MAAI_HUMAN / O43708 Maleylacetoacetate isomerase; MAAI; GSTZ1-1; Glutathione S-transferase zeta 1; EC 5.2.1.2; EC 2.5.1.18 from Homo sapiens (Human) (see 3 papers)
O43708 glutathione transferase (EC 2.5.1.18); maleylacetoacetate isomerase (EC 5.2.1.2) from Homo sapiens (see 8 papers)
    26% identity, 72% coverage of query (47.4 bits)

6m1tA / O30347 Bacterial beta class sphingomonas chungbukensis glutathione s- transferase
    29% identity, 89% coverage of query (47.4 bits)

3qagA / Q9H4Y5 Human glutathione transferase o2 with glutathione -new crystal form (see paper)
    27% identity, 81% coverage of query (47.0 bits)

4kdxA / B1FZ96 Crystal structure of a glutathione transferase family member from burkholderia graminis, target efi-507264, bound gsh, ordered domains, space group p21, form(1)
    29% identity, 71% coverage of query (46.6 bits)

2dsaA Ternary complex of bphk, a bacterial gst
    27% identity, 74% coverage of query (46.2 bits)

2gdrA / Q59721 Crystal structure of a bacterial glutathione transferase (see paper)
    27% identity, 74% coverage of query (46.2 bits)

7zznA Crystal structure of poplar glutathione transferase u20
    26% identity, 71% coverage of query (46.2 bits)

8ai8A / Q55139 Crystal structure of glutathione transferase chi 1 from synechocystis sp. Pcc 6803 in complex with glutathione (see paper)
    29% identity, 83% coverage of query (45.8 bits)

7pkaA Synechocystis sp. Pcc6803 glutathione transferase chi 1, gsoh bound
    29% identity, 83% coverage of query (45.8 bits)

GSTFC_ARATH / Q9FE46 Glutathione S-transferase F12; AtGSTF12; GST class-phi member 12; Glutathione S-transferase 26; Protein TRANSPARENT TESTA 19; EC 2.5.1.18 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
    26% identity, 70% coverage of query (45.8 bits)

6wegD Structure of ft (mgla-sspa)-ppgpp-pigr peptide complex
    24% identity, 88% coverage of query (45.8 bits)

6wmtS F. Tularensis rnaps70-(mgla-sspa)-ppgpp-pigr-igla DNA complex (see paper)
    24% identity, 88% coverage of query (45.4 bits)

6tahB 6tahB
    27% identity, 92% coverage of query (45.4 bits)

4ielB / Q0B681 Crystal structure of a glutathione s-transferase family protein from burkholderia ambifaria, target efi-507141, with bound glutathione
    29% identity, 70% coverage of query (45.4 bits)

4ecjA Crystal structure of glutathione s-transferase prk13972 (target efi- 501853) from pseudomonas aeruginosa pacs2 complexed with glutathione
    26% identity, 92% coverage of query (45.4 bits)

4zbbA Crystal structure of the glutathione transferase ure2p8 from phanerochaete chrysosporium complexed with glutathionyl-s- dinitrobenzene.
    25% identity, 91% coverage of query (43.1 bits)

4zbaA / A0A0R4I985 Crystal structure of the glutathione transferase ure2p8 from phanerochaete chrysosporium with oxidized glutathione. (see paper)
    24% identity, 91% coverage of query (43.1 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory