Searching for up to 100 curated homologs for RR42_RS36655 FitnessBrowser__Cup4G11:RR42_RS36655 (512 a.a.)
Found high-coverage hits (≥70%) to 58 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
ILVX_MYCTU / O53554 Putative acetolactate synthase large subunit IlvX; ALS; Acetohydroxy-acid synthase large subunit; AHAS; EC 2.2.1.6 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
O53554 acetolactate synthase (EC 2.2.1.6) from Mycobacterium tuberculosis (see paper)
48% identity, 100% coverage of query (401 bits)
Build an alignment for RR42_RS36655 and 1 homologs with ≥ 30% identity
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dpgB / A3RJV5 benzoylformate decarboxylase monomer (EC 4.1.1.7) from Stutzerimonas stutzeri (see paper)
28% identity, 100% coverage of query (139 bits)
bfd / CAK95977.1 benzoylformate decarboxylase from Pseudomonas putida (see paper)
29% identity, 97% coverage of query (138 bits)
6a50A Structure of benzoylformate decarboxylases in complex with cofactor tpp
29% identity, 97% coverage of query (137 bits)
bfd / CAK95976.1 benzoylformate decarboxylase from Pseudomonas putida (see paper)
29% identity, 94% coverage of query (136 bits)
mdlC / P20906 MdlC (EC 4.1.1.7) from Pseudomonas putida (see 2 papers)
P20906 benzoylformate decarboxylase (EC 4.1.1.7) from Pseudomonas putida (see 16 papers)
29% identity, 97% coverage of query (135 bits)
5deiA Benzoylformate decarboxylase from pseudomonas putida
29% identity, 97% coverage of query (135 bits)
3fsjX Crystal structure of benzoylformate decarboxylase in complex with the inhibitor mbp
29% identity, 97% coverage of query (135 bits)
1mczA Benzoylformate decarboxylase from pseudomonas putida complexed with an inhibitor, r-mandelate
29% identity, 97% coverage of query (135 bits)
3fznA Intermediate analogue in benzoylformate decarboxylase
29% identity, 97% coverage of query (135 bits)
1bfdA Benzoylformate decarboxylase from pseudomonas putida
29% identity, 97% coverage of query (135 bits)
3f6bX Crystal structure of benzoylformate decarboxylase in complex with the pyridyl inhibitor paa
29% identity, 97% coverage of query (135 bits)
1pi3A E28q mutant benzoylformate decarboxylase from pseudomonas putida
28% identity, 97% coverage of query (134 bits)
6qsiA / Q4KB02 Pseudomonas fluorescens pf-5 thiamine diphosphate-dependent 4- hydroxybenzoylformate decarboxylase (see paper)
29% identity, 97% coverage of query (132 bits)
7orxCCC / Q0SCE8 jostii RHA1 thiamine diphosphate-dependent 4-hydroxybenzoylformate decarboxylase
28% identity, 99% coverage of query (117 bits)
4q9dB / A0QSU7 X-ray structure of a putative thiamin diphosphate-dependent enzyme isolated from mycobacterium smegmatis (see paper)
29% identity, 97% coverage of query (115 bits)
4k9qA / A4SXU0 The crystal structure of benzoylformate decarboxylase from polynucleobacter necessarius
24% identity, 97% coverage of query (98.2 bits)
Q5SJ01 acetolactate synthase (EC 2.2.1.6); pyruvate decarboxylase (EC 4.1.1.1) from Thermus thermophilus (see paper)
27% identity, 100% coverage of query (86.7 bits)
ILVG_MYCTU / P9WG39 Acetolactate synthase large subunit IlvG; ALS; Acetohydroxy-acid synthase large subunit; AHAS; EC 2.2.1.6 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
P9WG39 acetolactate synthase (EC 2.2.1.6) from Mycobacterium tuberculosis (see 2 papers)
27% identity, 86% coverage of query (84.0 bits)
1y9dD / P37063 Pyruvate oxidase variant v265a from lactobacillus plantarum (see paper)
25% identity, 99% coverage of query (77.4 bits)
4feeA High-resolution structure of pyruvate oxidase in complex with reaction intermediate 2-hydroxyethyl-thiamin diphosphate carbanion-enamine, crystal b (see paper)
24% identity, 99% coverage of query (75.1 bits)
P37063 pyruvate oxidase (EC 1.2.3.3) from Lactiplantibacillus plantarum (see 2 papers)
24% identity, 99% coverage of query (74.7 bits)
ILVG_ECOLI / P0DP90 Acetolactate synthase isozyme 2 large subunit; AHAS-II; ALS-II; Acetohydroxy-acid synthase II large subunit; EC 2.2.1.6 from Escherichia coli (strain K12) (see 2 papers)
ilvG / GB|CAA28573.1 acetolactate synthase isozyme 2 large subunit; EC 2.2.1.6 from Escherichia coli K12 (see 8 papers)
24% identity, 100% coverage of query (74.7 bits)
1powA The refined structures of a stabilized mutant and of wild-type pyruvate oxidase from lactobacillus plantarum
24% identity, 99% coverage of query (74.7 bits)
ILVB1_MYCTU / P9WG41 Acetolactate synthase large subunit IlvB1; ALS; Acetohydroxy-acid synthase large subunit; AHAS; EC 2.2.1.6 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 4 papers)
P9WG41 acetolactate synthase (subunit 2/2) (EC 2.2.1.6) from Mycobacterium tuberculosis (see paper)
23% identity, 100% coverage of query (73.9 bits)
2ezuA Pyruvate oxidase variant f479w in complex with reaction intermediate 2-acetyl-thiamin diphosphate
24% identity, 99% coverage of query (73.9 bits)
2ez9A Pyruvate oxidase variant f479w in complex with reaction intermediate analogue 2-phosphonolactyl-thiamin diphosphate
24% identity, 99% coverage of query (73.9 bits)
2ez8A Pyruvate oxidase variant f479w in complex with reaction intermediate 2-lactyl-thiamin diphosphate
24% identity, 99% coverage of query (73.9 bits)
2ez4B Pyruvate oxidase variant f479w
24% identity, 99% coverage of query (73.9 bits)
Q2UKV4 phenylpyruvate decarboxylase (EC 4.1.1.43) from Aspergillus oryzae (see paper)
24% identity, 86% coverage of query (68.9 bits)
4rjkF Acetolactate synthase from bacillus subtilis bound to lthdp - crystal form ii
21% identity, 99% coverage of query (68.9 bits)
4rjkG Acetolactate synthase from bacillus subtilis bound to lthdp - crystal form ii
21% identity, 99% coverage of query (68.9 bits)
4rjiC Acetolactate synthase from bacillus subtilis bound to thdp - crystal form i (see paper)
21% identity, 99% coverage of query (68.6 bits)
Q04789 acetolactate synthase (EC 2.2.1.6); branched-chain-2-oxoacid decarboxylase (EC 4.1.1.72) from Bacillus subtilis (see 2 papers)
21% identity, 99% coverage of query (68.2 bits)
ipdC / P23234 indole-3-pyruvate decarboxylase subunit (EC 4.1.1.74) from Enterobacter cloacae (see 2 papers)
DCIP_ENTCL / P23234 Indole-3-pyruvate decarboxylase; Indolepyruvate decarboxylase; EC 4.1.1.74 from Enterobacter cloacae (see paper)
P23234 indolepyruvate decarboxylase (EC 4.1.1.74) from Enterobacter cloacae (see paper)
25% identity, 86% coverage of query (67.8 bits)
SYNPCC7002_A2770 / B1XMM5 2-oxoglutarate decarboxylase monomer (EC 4.1.1.71) from Synechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6) (see 2 papers)
B1XMM5 oxoglutarate dehydrogenase (succinyl-transferring) (EC 1.2.4.2) from Synechococcus sp. PCC 7002 (see paper)
22% identity, 95% coverage of query (67.8 bits)
xsc / Q84H44 sulfoacetaldehyde acetyltransferase monomer (EC 2.3.3.15) from Castellaniella defragrans (see paper)
XSC_CASDE / Q84H44 Sulfoacetaldehyde acetyltransferase; EC 2.3.3.15 from Castellaniella defragrans (Alcaligenes defragrans) (see paper)
Q84H44 sulfoacetaldehyde acetyltransferase (EC 2.3.3.15) from Castellaniella defragrans (see paper)
23% identity, 86% coverage of query (66.6 bits)
1ovmA / P23234 Crystal structure of indolepyruvate decarboxylase from enterobacter cloacae (see paper)
26% identity, 86% coverage of query (65.9 bits)
ilvB / AAB38426.1 acetolactate synthase from Mycobacterium avium (see paper)
23% identity, 100% coverage of query (63.2 bits)
Q836A5 acetolactate synthase (EC 2.2.1.6) from Enterococcus faecalis (see 2 papers)
21% identity, 99% coverage of query (60.8 bits)
C2E3B5 oxalyl-CoA decarboxylase (EC 4.1.1.8) from Lactobacillus johnsonii (see paper)
24% identity, 85% coverage of query (57.0 bits)
D4C4C5 oxalyl-CoA decarboxylase (EC 4.1.1.8) from Providencia rettgeri (see paper)
25% identity, 100% coverage of query (55.1 bits)
1ozfA The crystal structure of klebsiella pneumoniae acetolactate synthase with enzyme-bound cofactors
23% identity, 87% coverage of query (53.5 bits)
5dx6B / P27696 Acetolactate synthase from klebsiella pneumoniae soaked with beta- fluoropyruvate
22% identity, 87% coverage of query (53.1 bits)
6efgD / Q12629 Pyruvate decarboxylase from kluyveromyces lactis
22% identity, 92% coverage of query (52.4 bits)
1ozgA The crystal structure of klebsiella pneumoniae acetolactate synthase with enzyme-bound cofactor and with an unusual intermediate
23% identity, 87% coverage of query (51.2 bits)
5dx6A Acetolactate synthase from klebsiella pneumoniae soaked with beta- fluoropyruvate
23% identity, 87% coverage of query (50.4 bits)
8hp4A / C5MDS4 Ctpdc complex
22% identity, 85% coverage of query (50.1 bits)
8i07D Crystal structure of escherichia coli glyoxylate carboligase double mutant in complex with glycolaldehyde
23% identity, 100% coverage of query (49.7 bits)
8i07A Crystal structure of escherichia coli glyoxylate carboligase double mutant in complex with glycolaldehyde
23% identity, 100% coverage of query (49.7 bits)
5d6rB Acetolactate synthase from klebsiella pneumoniae in complex with mechanism-based inhibitor
23% identity, 87% coverage of query (49.3 bits)
8i01A / P0AEP7 Crystal structure of escherichia coli glyoxylate carboligase
23% identity, 100% coverage of query (48.9 bits)
8beoB Crystal structure of e. Coli glyoxylate carboligase mutant i393a with map
23% identity, 100% coverage of query (48.1 bits)
8beoA Crystal structure of e. Coli glyoxylate carboligase mutant i393a with map
23% identity, 100% coverage of query (48.1 bits)
2vbiA / Q8L388 Holostructure of pyruvate decarboxylase from acetobacter pasteurianus
24% identity, 85% coverage of query (47.8 bits)
5wdgA Acetolactate synthase from klebsiella pneumoniae in complex with a reaction intermediate
22% identity, 87% coverage of query (47.8 bits)
6efhA Pyruvate decarboxylase from kluyveromyces lactis soaked with pyruvamide
21% identity, 92% coverage of query (47.0 bits)
2vjyA / Q12629 Pyruvate decarboxylase from kluyveromyces lactis in complex with the substrate analogue methyl acetylphosphonate (see paper)
21% identity, 92% coverage of query (46.6 bits)
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Lawrence Berkeley National Laboratory