Searching for up to 100 curated homologs for RR42_RS36985 FitnessBrowser__Cup4G11:RR42_RS36985 (270 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
4zv1A An ancestral arginine-binding protein bound to arginine (see paper)
40% identity, 82% coverage of query (145 bits)
4zv2A An ancestral arginine-binding protein bound to glutamine
39% identity, 82% coverage of query (145 bits)
TcyJ / b1920 cystine ABC transporter periplasmic binding protein (EC 7.4.2.12) from Escherichia coli K-12 substr. MG1655 (see 12 papers)
tcyJ / P0AEM9 cystine ABC transporter periplasmic binding protein (EC 7.4.2.12) from Escherichia coli (strain K12) (see 13 papers)
TCYJ_ECOLI / P0AEM9 L-cystine-binding protein TcyJ; CBP; Protein FliY; Sulfate starvation-induced protein 7; SSI7 from Escherichia coli (strain K12) (see 6 papers)
TC 3.A.1.3.10 / P0AEM9 Cystine-binding periplasmic protein FLIY aka CysX aka B1920, component of Cystine/cysteine/diaminopimelate transporter, CysXYZ; these proteins are also designated FliY/YecS/YecC from Escherichia coli (see 7 papers)
36% identity, 93% coverage of query (142 bits)
5eyfB / Q3XZW5 Crystal structure of solute-binding protein from enterococcus faecium with bound glutamate
35% identity, 79% coverage of query (119 bits)
2yjpA / Q5F5B5 Crystal structure of the solute receptors for l-cysteine of neisseria gonorrhoeae (see paper)
34% identity, 84% coverage of query (114 bits)
cjaA / CAJ20048.1 glutamine-binding protein from Campylobacter jejuni (see paper)
32% identity, 92% coverage of query (114 bits)
1xt8B / Q0P9S0 Crystal structure of cysteine-binding protein from campylobacter jejuni at 2.0 a resolution (see paper)
32% identity, 84% coverage of query (111 bits)
6svfA / Q9WZ62 Crystal structure of the p235gk mutant of argbp from t. Maritima (see paper)
36% identity, 84% coverage of query (110 bits)
5t0wA Crystal structure of the ancestral amino acid-binding protein anccdt- 1, a precursor of cyclohexadienyl dehydratase
32% identity, 84% coverage of query (109 bits)
3vvdA / Q72JG5 Crystal structure of ttc0807 complexed with ornithine (see paper)
33% identity, 84% coverage of query (107 bits)
GLNH_BACSU / O34563 ABC transporter glutamine-binding protein GlnH from Bacillus subtilis (strain 168) (see paper)
31% identity, 87% coverage of query (107 bits)
3vvfA Crystal structure of ttc0807 complexed with arginine
33% identity, 84% coverage of query (107 bits)
3vveA Crystal structure of ttc0807 complexed with lysine
33% identity, 84% coverage of query (107 bits)
3vv5A Crystal structure of ttc0807 complexed with (s)-2-aminoethyl-l- cysteine (aec)
33% identity, 84% coverage of query (107 bits)
ArtJ / b0860 L-arginine ABC transporter periplasmic binding protein (EC 7.4.2.1) from Escherichia coli K-12 substr. MG1655 (see paper)
ArtJ / P30860 L-arginine ABC transporter periplasmic binding protein (EC 7.4.2.1) from Escherichia coli (strain K12) (see paper)
ARTJ_ECOLI / P30860 ABC transporter arginine-binding protein 1 from Escherichia coli (strain K12) (see paper)
TC 3.A.1.3.3 / P30860 ArtJ aka B0860, component of Arginine porter from Escherichia coli (see 7 papers)
artJ / GB|BAA35574.1 arginine ABC transporter, periplasmic arginine-binding protein ArtJ from Escherichia coli K12 (see 8 papers)
30% identity, 81% coverage of query (103 bits)
Build an alignment for RR42_RS36985 and 15 homologs with ≥ 30% identity
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ArtI / b0863 putative ABC transporter periplasmic binding protein ArtI from Escherichia coli K-12 substr. MG1655 (see 3 papers)
ARTI_ECOLI / P30859 Putative ABC transporter arginine-binding protein 2 from Escherichia coli (strain K12) (see paper)
TC 3.A.1.3.3 / P30859 ArtI aka B0863, component of Arginine porter from Escherichia coli (see 7 papers)
29% identity, 82% coverage of query (100 bits)
ArgT / b2310 lysine/arginine/ornithine ABC transporter periplasmic binding protein (EC 7.4.2.1) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
TC 3.A.1.3.1 / TC 3.A.1.3.29 / P09551 ArgT aka B2310, component of Histidine/Arginine/Lysine (basic amino acid) uptake porter, HisJ/ArgT/HisP/HisM/HisQ [R, R, C, M, M, respectively] (Gilson et al. 1982). HisJ binds L-His (preferred), but 1-methyl-L-His and 3-methyl-L-His also bind, while the dipeptide carnosine binds weakly; D-histidine and the histidine degradation products, histamine, urocanic acid and imidazole do not bind. L-Arg, homo-L-Arg, and post-translationally modified methylated Arg-analogs also bind with the exception of symmetric dimethylated-L-Arg. L-Lys and L-Orn show weaker interactions with HisJ and methylated and acetylated Lys variants show poor binding.The carboxylate groups of these amino acids and their variants are essential from Escherichia coli (see 5 papers)
32% identity, 91% coverage of query (95.5 bits)
2pvuA Crystal structures of the arginine-, lysine-, histidine-binding protein artj from the thermophilic bacterium geobacillus stearothermophilus
31% identity, 80% coverage of query (91.7 bits)
2q2aA / D0VWX8 Crystal structures of the arginine-, lysine-, histidine-binding protein artj from the thermophilic bacterium geobacillus stearothermophilus (see paper)
31% identity, 80% coverage of query (91.3 bits)
2q2cA Crystal structures of the arginine-, lysine-, histidine-binding protein artj from the thermophilic bacterium geobacillus stearothermophilus
31% identity, 80% coverage of query (91.3 bits)
GASBP_PSEAE / Q9I402 L-glutamate/L-aspartate-binding protein from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
TC 3.A.1.3.22 / Q9I402 Probable binding protein component of ABC transporter, component of Amino acid transporter, AatJMQP. Probably transports L-glutamic acid, D-glutamine acid, L-glutamine and N-acetyl L-glutamic acid (Johnson et al. 2008). Very similar to 3.A.1.3.19 of P. putida from Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
28% identity, 95% coverage of query (90.5 bits)
ARGT_SALTY / P02911 Lysine/arginine/ornithine-binding periplasmic protein; LAO-binding protein from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 6 papers)
argT / RF|NP_461297.1 lysine/arginine/ornithine ABC transporter, periplasmic lysine/arginine/ornithine-binding protein ArgT from Salmonella enterica subsp. enterica serovar Typhimurium (see 4 papers)
29% identity, 91% coverage of query (87.8 bits)
2ia4B / A0A0H2UXX1 Crystal structure of novel amino acid binding protein from shigella flexneri
28% identity, 94% coverage of query (87.4 bits)
2vhaA Debp
28% identity, 94% coverage of query (87.0 bits)
6h2tA / P96257 Glnh bound to glu, mycobacterium tuberculosis (see paper)
30% identity, 87% coverage of query (86.7 bits)
AO353_16290 ABC transporter for L-aspartate, L-asparagine, L-glutamate, and L-glutamine, periplasmic substrate-binding component from Pseudomonas fluorescens FW300-N2E3
27% identity, 88% coverage of query (86.7 bits)
6h20A Glnh bound to asn, mycobacterium tuberculosis
30% identity, 87% coverage of query (86.7 bits)
6h1uA Glnh bound to asp, mycobacterium tuberculosis
30% identity, 87% coverage of query (86.7 bits)
Pf1N1B4_771 ABC transporter for L-asparagine and L-glutamate, periplasmic substrate-binding component from Pseudomonas fluorescens FW300-N1B4
27% identity, 84% coverage of query (85.9 bits)
2y7iA / Q8ZKA9 Structural basis for high arginine specificity in salmonella typhimurium periplasmic binding protein stm4351. (see paper)
29% identity, 82% coverage of query (84.7 bits)
4ymxA / Q8RCC4 Crystal structure of the substrate binding protein of an amino acid abc transporter (see paper)
28% identity, 81% coverage of query (84.7 bits)
5owfA Structure of a lao-binding protein mutant with glutamine
29% identity, 81% coverage of query (84.7 bits)
3k4uE / Q7MAG0 Crystal structure of putative binding component of abc transporter from wolinella succinogenes dsm 1740 complexed with lysine
29% identity, 81% coverage of query (84.0 bits)
GlnH / b0811 L-glutamine ABC transporter periplasmic binding protein (EC 7.4.2.1) from Escherichia coli K-12 substr. MG1655 (see 13 papers)
GlnH / P0AEQ3 L-glutamine ABC transporter periplasmic binding protein (EC 7.4.2.1) from Escherichia coli (strain K12) (see 13 papers)
GLNH_ECOLI / P0AEQ3 Glutamine-binding periplasmic protein; GlnBP from Escherichia coli (strain K12) (see paper)
TC 3.A.1.3.2 / P0AEQ3 Glutamine-binding periplasmic protein GlnH aka B0811 aka GlnBP, component of Three component ABC L-glutamine porter. The basal ATPase activity (ATP hydrolysis in the absence of substrate) is mainly caused by the docking of the closed-unliganded state of GlnH onto the transporter domain of GlnPQ. Unlike glutamine, arginine binds both GlnH domains, but does not trigger their closing. Comparison of the ATPase activity in nanodiscs with glutamine transport in proteoliposomes suggested that the stoichiometry of ATP per substrate is close to two from Escherichia coli (see 7 papers)
glnH / GB|AAN79369.1 glutamine ABC transporter, periplasmic glutamine-binding protein GlnH from Escherichia coli (see 7 papers)
31% identity, 77% coverage of query (84.0 bits)
1lafE / P02911 Structural bases for multiple ligand specificity of the periplasmic lysine-, arginine-, ornithine-binding protein (see paper)
29% identity, 81% coverage of query (83.6 bits)
HISJ_CAMJE / Q46125 Probable histidine-binding protein; HBP; p29 from Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168) (see paper)
31% identity, 76% coverage of query (83.6 bits)
1lstA Three-dimensional structures of the periplasmic lysine-, arginine-, ornithine-binding protein with and without a ligand
29% identity, 81% coverage of query (83.6 bits)
1lahE Structural bases for multiple ligand specificity of the periplasmic lysine-, arginine-, ornithine-binding protein
29% identity, 81% coverage of query (83.6 bits)
1lagE Structural bases for multiple ligand specificity of the periplasmic lysine-, arginine-, ornithine-binding protein
29% identity, 81% coverage of query (83.6 bits)
GltI / b0655 glutamate/aspartate ABC transporter periplasmic binding protein (EC 7.4.2.1) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
GltI / P37902 glutamate/aspartate ABC transporter periplasmic binding protein (EC 7.4.2.1) from Escherichia coli (strain K12) (see 3 papers)
GLTI_ECOLI / P37902 Glutamate/aspartate import solute-binding protein from Escherichia coli (strain K12) (see 3 papers)
TC 3.A.1.3.4 / P37902 YBEJ aka GltI aka B0655, component of Glutamate/aspartate porter from Escherichia coli (see 6 papers)
gltI / GB|BAA35307.2 glutamate-aspartate periplasmic-binding protein from Escherichia coli K12 (see 6 papers)
28% identity, 91% coverage of query (83.2 bits)
4h5fA Crystal structure of an amino acid abc transporter substrate-binding protein from streptococcus pneumoniae canada mdr_19a bound to l- arginine, form 1
28% identity, 80% coverage of query (82.8 bits)
TC 3.A.1.3.19 / Q88NY2 PP1071, component of Acidic amino acid uptake porter, AatJMQP from Pseudomonas putida (strain KT2440) (see paper)
28% identity, 94% coverage of query (82.8 bits)
8eyzA / P0AEQ3 Engineered glutamine binding protein bound to gln and a cobaloxime ligand (see paper)
31% identity, 77% coverage of query (82.4 bits)
TC 3.A.1.3.17 / Q8YSA2 Basic amino acid uptake transporter, BgtAB (see paper)
29% identity, 83% coverage of query (82.0 bits)
TC 3.A.1.3.21 / Q9I484 Amino acid ABC transporter periplasmic binding protein, component of Hydroxy L-proline uptake porter, HprABC from Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
31% identity, 89% coverage of query (81.3 bits)
TC 3.A.1.3.23 / Q9HU31 Amino acid (Lysine/arginine/ornithine/histidine/octopine) ABC transporter periplasmic binding protein, component of Amino acid transporter, PA5152-PA5155. Probably transports numerous amino acids including lysine, arginine, histidine, D-alanine and D-valine (Johnson et al. 2008). Regulated by ArgR from Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
30% identity, 82% coverage of query (81.3 bits)
5lomB / Q7D447 Crystal structure of the pbp soca from agrobacterium tumefaciens c58 in complex with dfg at 1.5 a resolution (see paper)
29% identity, 84% coverage of query (80.5 bits)
5l9oB Crystal structure of agrobacterium tumefaciens c58 strain pbp soca in complex with glucopine
29% identity, 84% coverage of query (80.1 bits)
5l9oA Crystal structure of agrobacterium tumefaciens c58 strain pbp soca in complex with glucopine
29% identity, 84% coverage of query (80.1 bits)
8ovoA / P37902,P42212 X-ray structure of the sf-iglusnfr-s72a in complex with l-aspartate
28% identity, 84% coverage of query (79.7 bits)
6detA / S3MDF0 The crystal structure of tv2483 bound to l-arginine (see paper)
28% identity, 83% coverage of query (75.1 bits)
2pyyB / D0VWX9 Crystal structure of the glur0 ligand-binding core from nostoc punctiforme in complex with (l)-glutamate (see paper)
29% identity, 79% coverage of query (73.9 bits)
4zefA / Q837S0 Crystal structure of substrate binding domain 2 (sbd2) of abc transporter glnpq from enterococcus faecalis
31% identity, 73% coverage of query (73.6 bits)
HisJ / b2309 histidine ABC transporter periplasmic binding protein (EC 7.4.2.1) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
HISJ_ECOLI / P0AEU0 Histidine-binding periplasmic protein; HBP from Escherichia coli (strain K12) (see paper)
TC 3.A.1.3.29 / P0AEU0 Histidine-binding periplasmic protein, component of Histidine/Arginine/Lysine (basic amino acid) uptake porter, HisJ/ArgT/HisP/HisM/HisQ [R, R, C, M, M, respectively] (Gilson et al. 1982). HisJ binds L-His (preferred), but 1-methyl-L-His and 3-methyl-L-His also bind, while the dipeptide carnosine binds weakly; D-histidine and the histidine degradation products, histamine, urocanic acid and imidazole do not bind. L-Arg, homo-L-Arg, and post-translationally modified methylated Arg-analogs also bind with the exception of symmetric dimethylated-L-Arg. L-Lys and L-Orn show weaker interactions with HisJ and methylated and acetylated Lys variants show poor binding.The carboxylate groups of these amino acids and their variants are essential from Escherichia coli (strain K12)
hisJ / GB|AAC75369.1 histidine ABC transporter, periplasmic histidine-binding protein HisJ from Escherichia coli (see 7 papers)
27% identity, 73% coverage of query (73.2 bits)
4g4pA / Q837S0 Crystal structure of glutamine-binding protein from enterococcus faecalis at 1.5 a (see paper)
29% identity, 77% coverage of query (72.4 bits)
4i62A / A0A0H2ZN67 1.05 angstrom crystal structure of an amino acid abc transporter substrate-binding protein abpa from streptococcus pneumoniae canada mdr_19a bound to l-arginine
26% identity, 83% coverage of query (71.2 bits)
8gu1A Crystal structure of putative amino acid binding periplasmic abc transporter protein from candidatus liberibacter asiaticus in complex with pimozide
26% identity, 81% coverage of query (71.2 bits)
6aalA Crystal structure of putative amino acid binding periplasmic abc transporter protein from candidatus liberibacter asiaticus in complex with arginine
26% identity, 81% coverage of query (71.2 bits)
6a80A Crystal structure of putative amino acid binding periplasmic abc transporter protein from candidatus liberibacter asiaticus in complex with cystine
26% identity, 81% coverage of query (71.2 bits)
HISJ_SALTY / P02910 Histidine-binding periplasmic protein; HBP from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 4 papers)
hisJ / GB|AAV76512.1 histidine ABC transporter, periplasmic histidine-binding protein HisJ from Salmonella enterica subsp. enterica serovar Typhimurium (see 5 papers)
27% identity, 81% coverage of query (70.9 bits)
8gtuA / C6XGT2 Crystal structure of putative amino acid binding periplasmic abc transporter protein from candidatus liberibacter asiaticus in complex with clidinium (see paper)
26% identity, 81% coverage of query (70.9 bits)
1hslA / P0AEU0 Refined 1.89 angstroms structure of the histidine-binding protein complexed with histidine and its relationship with many other active transport(slash)chemosensory receptors (see paper)
27% identity, 81% coverage of query (70.9 bits)
8b5dA Exploring the ligand binding and conformational dynamics of receptor domain 1 of the abc transporter glnpq
30% identity, 77% coverage of query (63.2 bits)
6fxgB / Q9CES5 Crystal structure of substrate binding domain 1 (sbd1) of abc transporter glnpq in complex with asparagine
30% identity, 77% coverage of query (62.8 bits)
8b5eA Exploring the ligand binding and conformational dynamics of receptor domain 1 of the abc transporter glnpq
30% identity, 77% coverage of query (62.8 bits)
5otcA Structure of the periplasmic binding protein (pbp) noct from agrobacterium tumefaciens c58 in complex with noroctopinic acid.
24% identity, 77% coverage of query (62.0 bits)
5otaA Structure of the periplasmic binding protein (pbp) noct from agrobacterium tumefaciens c58 in complex with octopinic acid
24% identity, 77% coverage of query (62.0 bits)
5ot9A Structure of the periplasmic binding protein (pbp) noct from a.Tumefaciens c58 in complex with histopine.
24% identity, 77% coverage of query (62.0 bits)
4powA Structure of the pbp noct in complex with pyronopaline
24% identity, 77% coverage of query (62.0 bits)
5ovzA / P35120 High resolution structure of the pbp noct in complex with nopaline (see paper)
24% identity, 77% coverage of query (62.0 bits)
5itoA Structure of the periplasmic binding protein m117n-noct from a. Tumefaciens in complex with octopine
24% identity, 77% coverage of query (59.7 bits)
4ohnA / A0A0H2UKY8 Crystal structure of an abc uptake transporter substrate binding protein from streptococcus pneumoniae with bound histidine
22% identity, 78% coverage of query (58.9 bits)
2ylnA / Q5F9M1 Crystal structure of the l-cystine solute receptor of neisseria gonorrhoeae in the closed conformation (see paper)
26% identity, 84% coverage of query (54.7 bits)
3i6vA / Q5LTV6 Crystal structure of a periplasmic his/glu/gln/arg/opine family- binding protein from silicibacter pomeroyi in complex with lysine
24% identity, 81% coverage of query (53.9 bits)
4kqpA / Q9CES5 Crystal structure of lactococcus lactis glnp substrate binding domain 2 (sbd2) in complex with glutamine at 0.95 a resolution (see paper)
26% identity, 72% coverage of query (53.5 bits)
P16575 Virulence sensor protein BvgS; EC 2.7.13.3 from Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)
26% identity, 81% coverage of query (50.8 bits)
5kuhA / P42260 Gluk2em with ly466195 (see paper)
25% identity, 72% coverage of query (48.9 bits)
ARTJ_CHLPN / Q9Z869 Probable ABC transporter arginine-binding protein ArtJ from Chlamydia pneumoniae (Chlamydophila pneumoniae) (see 2 papers)
24% identity, 83% coverage of query (48.9 bits)
5ehsA Crystal structure of the drosophila cg3822 kair1d ligand binding domain complex with d-ap5
25% identity, 73% coverage of query (48.9 bits)
3qaxB / Q9Z869 Crystal structure analysis of the cpb0502
24% identity, 80% coverage of query (48.5 bits)
5dtbA / Q9VDH5 Crystal structure of the drosophila cg3822 kair1d ligand binding domain complex with glutamate (see paper)
25% identity, 73% coverage of query (48.5 bits)
5ehmA Crystal structure of the drosophila cg3822 kair1d ligand binding domain complex with nmda
25% identity, 73% coverage of query (48.5 bits)
3en3A Crystal structure of the glur4 ligand-binding domain in complex with kainate
25% identity, 72% coverage of query (47.8 bits)
3fasA / P19493 X-ray structure of iglur4 flip ligand-binding core (s1s2) in complex with (s)-glutamate at 1.40a resolution (see paper)
25% identity, 72% coverage of query (47.8 bits)
4f29A Quisqualate bound to the ligand binding domain of glua3i
25% identity, 72% coverage of query (47.0 bits)
3rt8A Chlorowillardiine bound to the ligand binding domain of glua3
25% identity, 72% coverage of query (47.0 bits)
3rt6B Fluorowillardiine bound to the ligand binding domain of glua3
25% identity, 72% coverage of query (47.0 bits)
3lswA Aniracetam bound to the ligand binding domain of glua3
25% identity, 72% coverage of query (47.0 bits)
3dp4A Crystal structure of the binding domain of the ampa subunit glur3 bound to ampa
25% identity, 72% coverage of query (47.0 bits)
3o28A Ligand-binding domain of glua2 (flip) ionotropic glutamate receptor in complex with an allosteric modulator
23% identity, 72% coverage of query (46.6 bits)
2xhdA Crystal structure of n-((2s)-5-(6-fluoro-3-pyridinyl)-2,3- dihydro-1h-inden-2-yl)-2-propanesulfonamide in complex with the ligand binding domain of the human glua2 receptor
23% identity, 72% coverage of query (46.6 bits)
4u1oA Glua2flip slbd complexed with kainate and (r,r)-2b crystal form c
23% identity, 72% coverage of query (46.2 bits)
4fatA Ligand-binding domain of glua2 (flip) ionotropic glutamate receptor in complex with an allosteric modulator
23% identity, 72% coverage of query (46.2 bits)
3pmxA Ligand-binding domain of glua2 (flip) ionotropic glutamate receptor in complex with an allosteric modulator
23% identity, 72% coverage of query (46.2 bits)
3pmvA Ligand-binding domain of glua2 (flip) ionotropic glutamate receptor in complex with an allosteric modulator
23% identity, 72% coverage of query (46.2 bits)
3o6iA Ligand-binding domain of glua2 (flip) ionotropic glutamate receptor in complex with an allosteric modulator
23% identity, 72% coverage of query (46.2 bits)
3o6gA Ligand-binding domain of glua2 (flip) ionotropic glutamate receptor in complex with an allosteric modulator
23% identity, 72% coverage of query (46.2 bits)
3o29A Ligand-binding domain of glua2 (flip) ionotropic glutamate receptor in complex with an allosteric modulator
23% identity, 72% coverage of query (46.2 bits)
8i0bA The crystal structure of human glutamate receptor 2 in complex with lt-102
23% identity, 72% coverage of query (46.2 bits)
3o2aA Ligand-binding domain of glua2 (flip) ionotropic glutamate receptor in complex with an allosteric modulator
23% identity, 72% coverage of query (46.2 bits)
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Lawrence Berkeley National Laboratory