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Searching for up to 100 curated homologs for SM_b20099 FitnessBrowser__Smeli:SM_b20099 (544 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

Q1J0Z5 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Deinococcus geothermalis (see paper)
    43% identity, 98% coverage of query (436 bits)

Q9RST7 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Deinococcus radiodurans (see 2 papers)
    43% identity, 98% coverage of query (424 bits)

I3NX86 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Deinococcus radiodurans (see 4 papers)
    43% identity, 98% coverage of query (424 bits)

5gtwA / I3NX86 The n253r mutant structures of trehalose synthase from deinococcus radiodurans display two different active-site conformations
    43% identity, 98% coverage of query (417 bits)

5ykbD / I3NX86 The n253f mutant structure of trehalose synthase from deinococcus radiodurans reveals an open active-site conformation (see paper)
    42% identity, 98% coverage of query (406 bits)

D1ABU6 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Thermomonospora curvata (see 2 papers)
    42% identity, 91% coverage of query (399 bits)

Q47SE5 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Thermobifida fusca (see paper)
    41% identity, 91% coverage of query (398 bits)

8uzhB / P9WQ18,Q12306 Sumo fused trehalose synthase (tres) of mycobacterium tuberculosis (see paper)
    40% identity, 98% coverage of query (391 bits)

5x7uA / D1CE96 Trehalose synthase from thermobaculum terrenum (see paper)
    40% identity, 98% coverage of query (390 bits)

D1CE96 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Thermobaculum terrenum (see 4 papers)
    40% identity, 98% coverage of query (390 bits)

TRES_MYCTU / P9WQ19 Trehalose synthase/amylase TreS; Maltose alpha-D-glucosyltransferase; MTase; EC 3.2.1.1; EC 5.4.99.16 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 3 papers)
P9WQ19 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Mycobacterium tuberculosis (see paper)
    40% identity, 98% coverage of query (390 bits)

B6E9W1 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Enterobacter hormaechei (see paper)
    39% identity, 99% coverage of query (390 bits)

F5S1H2 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Enterobacter hormaechei (see paper)
    39% identity, 99% coverage of query (389 bits)

3zo9A The structure of trehalose synthase (tres) of mycobacterium smegmatis
    39% identity, 98% coverage of query (388 bits)

3zoaA The structure of trehalose synthase (tres) of mycobacterium smegmatis in complex with acarbose
    39% identity, 98% coverage of query (388 bits)

A8QX00 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Actinoplanes sp. (see paper)
    40% identity, 95% coverage of query (387 bits)

8uqvA Trehalose synthase (tres) of mycobacterium tuberculosis in complex with 6-treaz compound
    40% identity, 98% coverage of query (387 bits)

I3WCP4 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Pseudomonas sp. P8005 (see paper)
    39% identity, 99% coverage of query (384 bits)

Q88FN0 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Pseudomonas putida (see 2 papers)
    39% identity, 99% coverage of query (382 bits)

5jy7B / A0R6E0 Complex of mycobacterium smegmatis trehalose synthase with maltokinase (see paper)
    39% identity, 98% coverage of query (382 bits)

3zoaB The structure of trehalose synthase (tres) of mycobacterium smegmatis in complex with acarbose
    39% identity, 98% coverage of query (382 bits)

treS / A0R6E0 trehalose synthase subunit (EC 5.4.99.16) from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (see 4 papers)
TRES_MYCS2 / A0R6E0 Trehalose synthase/amylase TreS; Maltose alpha-D-glucosyltransferase; MTase; EC 3.2.1.1; EC 5.4.99.16 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see 6 papers)
A0R6E0 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Mycolicibacterium smegmatis (see 3 papers)
    39% identity, 98% coverage of query (381 bits)

B8YM30 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Paenarthrobacter aurescens (see 2 papers)
    39% identity, 98% coverage of query (381 bits)

B1PK99 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Meiothermus ruber (see 4 papers)
    43% identity, 90% coverage of query (380 bits)

Q6L2Z7 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Picrophilus torridus (see 2 papers)
    38% identity, 98% coverage of query (379 bits)

Q5SL15 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Thermus thermophilus (see paper)
    42% identity, 98% coverage of query (379 bits)

Q7WUI5 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Thermus thermophilus (see 2 papers)
    42% identity, 98% coverage of query (379 bits)

A0A2Z4RCL2 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Pseudomonas putida (see paper)
    38% identity, 99% coverage of query (375 bits)

A0A1I7MT66 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Micrococcus terreus (see paper)
    39% identity, 98% coverage of query (373 bits)

A0A4S2BJW1 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Pseudomonas stutzeri (see paper)
    38% identity, 99% coverage of query (371 bits)

M1PA89 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Rhodococcus opacus (see paper)
    37% identity, 98% coverage of query (371 bits)

4lxfB Crystal structure of m. Tuberculosis tres (see paper)
    39% identity, 98% coverage of query (363 bits)

O06458 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Thermus thermophilus (see 3 papers)
    40% identity, 98% coverage of query (361 bits)

A0A1R4FYB1 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Corynebacterium glutamicum (see 2 papers)
    35% identity, 100% coverage of query (357 bits)

2ze0A / Q33E90 Alpha-glucosidase gsj (see paper)
    33% identity, 90% coverage of query (254 bits)

AAP10934.1 oligo-α-1,6-glucosidase (BC4015) (EC 3.2.1.10) (see protein)
    30% identity, 90% coverage of query (248 bits)

Q33E90 alpha-glucosidase (EC 3.2.1.20) from Geobacillus sp. HTA-462 (see paper)
BAE48285.1 α-glucosidase (Gsj) (EC 3.2.1.20) (see protein)
    32% identity, 90% coverage of query (247 bits)

AAS80455.1 α,α-trehalase / α-glucosidase (TTC0107) (EC 3.2.1.20|3.2.1.28) (see protein)
    34% identity, 92% coverage of query (246 bits)

Build an alignment

Build an alignment for SM_b20099 and 38 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

CAA37583.1 oligo-α-1,6-glucosidase (MalL) (EC 3.2.1.10) (see protein)
    29% identity, 98% coverage of query (243 bits)

AKA95141.1 α-glucosidase (TtAG) (EC 3.2.1.20) (see protein)
    33% identity, 92% coverage of query (243 bits)

BAA12704.1 α-glucosidase / exo-α-1,4-glucosidase (EC 3.2.1.20) (see protein)
    31% identity, 90% coverage of query (241 bits)

O16G_PARTM / P29094 Oligo-1,6-glucosidase; Dextrin 6-alpha-D-glucanohydrolase; Oligosaccharide alpha-1,6-glucosidase; Sucrase-isomaltase; Isomaltase; EC 3.2.1.10 from Parageobacillus thermoglucosidasius (Geobacillus thermoglucosidasius) (see paper)
BAA01368.1 oligo-α-1,6-glucosidase (MalL) (EC 3.2.1.10) (see protein)
    30% identity, 94% coverage of query (239 bits)

A0A223KY92 alpha-amylase (EC 3.2.1.1) from Sutcliffiella cohnii (see paper)
    31% identity, 90% coverage of query (236 bits)

CAA55409.1 α-1,4-glucosidase (MalA) (EC 3.2.1.20) (see protein)
    30% identity, 90% coverage of query (235 bits)

Q5SL12 alpha-glucosidase (EC 3.2.1.20) from Thermus thermophilus HB8 (see paper)
BAD70304.1 α-glucosidase (TTHA0481) (EC 3.2.1.20) (see protein)
    32% identity, 92% coverage of query (234 bits)

BAB18518.1 oligo-α-1,6-glucosidase (EC 3.2.1.10) (see protein)
    32% identity, 92% coverage of query (234 bits)

AAD50603.1 α-glucosidase (EC 3.2.1.20) (see protein)
    33% identity, 82% coverage of query (233 bits)

BAA11354.1 oligo-α-1,6-glucosidase (MalL) (EC 3.2.1.10) (see protein)
    31% identity, 90% coverage of query (227 bits)

AAW32491.1 α-amylase (AmyA) (EC 3.2.1.1) (see protein)
    30% identity, 98% coverage of query (227 bits)

AAK27723.1 oligo α-glucosidase (AglA) (EC 3.2.1.10) (see protein)
    31% identity, 95% coverage of query (227 bits)

Q5FMB7 glucan 1,6-alpha-glucosidase (EC 3.2.1.70) from Lactobacillus acidophilus (see paper)
AAV42157.1 oligo-α-1,6-glucosidase (LBA0264) (EC 3.2.1.10) (see protein)
    30% identity, 91% coverage of query (226 bits)

4aieA / Q5FMB7 Structure of glucan-1,6-alpha-glucosidase from lactobacillus acidophilus ncfm (see paper)
    30% identity, 91% coverage of query (226 bits)

BAB38639.1 trehalose 6-P hydrolase (ECs5216) (EC 3.2.1.93) (see protein)
    30% identity, 98% coverage of query (221 bits)

C0JP82 oligo-1,6-glucosidase (EC 3.2.1.10) from Bifidobacterium breve (see paper)
ACM89182.1 α-1,6-glucosidase 1 (Agl1; Bbr_1855) (EC 3.2.1.10|3.2.1.20) (see protein)
    29% identity, 90% coverage of query (221 bits)

A1IHL0 alpha-glucosidase (EC 3.2.1.20) from Apis cerana japonica (see paper)
BAF44218.1 α-glucosidase I (JBgI) (EC 3.2.1.20) (see protein)
jbgI / BAF44218.1 alpha-glucosidase isozyme I from Apis cerana japonica (see paper)
    30% identity, 93% coverage of query (220 bits)

Q9ZAP8 neopullulanase (EC 3.2.1.135) from Paenibacillus polymyxa (see paper)
AAD05199.1 α-amylase (formerly neopullulanase) (EC 3.2.1.1) (see protein)
    32% identity, 89% coverage of query (220 bits)

C0JP83 oligo-1,6-glucosidase (EC 3.2.1.10) from Bifidobacterium breve (see paper)
ACM89183.1 α-1,6-glucosidase 2 (Agl2; Bbr_0559) (EC 3.2.1.10|3.2.1.20) (see protein)
    29% identity, 97% coverage of query (220 bits)

P20845 alpha-amylase (EC 3.2.1.1) from Priestia megaterium (see paper)
CAA30247.1 α-amylase (EC 3.2.1.1) (see protein)
    31% identity, 92% coverage of query (216 bits)

AAL07400.1 α-amylase / neopullulanase (Npl) (EC 3.2.1.1) (see protein)
    31% identity, 89% coverage of query (216 bits)

TreE / b4239 trehalose-6-phosphate hydrolase (EC 3.2.1.93) from Escherichia coli K-12 substr. MG1655 (see 7 papers)
treC / P28904 trehalose-6-phosphate hydrolase (EC 3.2.1.93) from Escherichia coli (strain K12) (see 4 papers)
TREC_ECOLI / P28904 Trehalose-6-phosphate hydrolase; Alpha,alpha-phosphotrehalase; EC 3.2.1.93 from Escherichia coli (strain K12) (see paper)
AAC77196.1 trehalose-6-phosphate hydrolase (TreC) (EC 3.2.1.93) (see protein)
    30% identity, 98% coverage of query (216 bits)

ABU54057.1 α-amylase (BMW-amylase) (EC 3.2.1.1) (see protein)
    31% identity, 92% coverage of query (216 bits)

Q65MI2 alpha,alpha-phosphotrehalase (EC 3.2.1.93) from Bacillus licheniformis (see 2 papers)
AAU39732.1 trehalose-6-P hydrolase (TreA;BlTreA;BLi00797;BL03069) (EC 3.2.1.93) (see protein)
    27% identity, 99% coverage of query (216 bits)

A0A0U4VEK2 alpha-amylase (EC 3.2.1.1) from Paenibacillus sp. SSG-1 (see paper)
    31% identity, 91% coverage of query (215 bits)

MAL2_DROME / P07191 Maltase A2; Larval visceral protein D; EC 3.2.1.20 from Drosophila melanogaster (Fruit fly) (see paper)
AAF59088.1 α-glucosidase D (LvpD) (EC 3.2.1.20) (see protein)
    30% identity, 81% coverage of query (215 bits)

AAX84031.1 α-amylase (AmyF) (EC 3.2.1.1) (see protein)
    31% identity, 92% coverage of query (215 bits)

Q99040 glucan 1,6-alpha-glucosidase (EC 3.2.1.70) from Streptococcus mutans serotype c (see paper)
    30% identity, 92% coverage of query (214 bits)

BAH14969.1 g-cyclodextrin-specific cyclodextrinase (Cda) (EC 3.2.1.54) (see protein)
    29% identity, 99% coverage of query (213 bits)

4wlcA / Q99040 Structure of dextran glucosidase with glucose (see paper)
    29% identity, 92% coverage of query (213 bits)

5wczA Crystal structure of wild-type mall from bacillus subtilis with ts analogue 1-deoxynojirimycin
    29% identity, 90% coverage of query (213 bits)

4m56A The structure of wild-type mall from bacillus subtilis
    29% identity, 90% coverage of query (213 bits)

2zidA Crystal structure of dextran glucosidase e236q complex with isomaltotriose
    29% identity, 92% coverage of query (213 bits)

O16G1_BACSU / O06994 Oligo-1,6-glucosidase 1; Dextrin 6-alpha-D-glucanohydrolase; Oligosaccharide alpha-1,6-glucosidase 1; Sucrase-isomaltase 1; Isomaltase 1; EC 3.2.1.10 from Bacillus subtilis (strain 168) (see 3 papers)
CAB15461.1 α-1,6-glucosidase (MalL;YvdL;BSU34560) (EC 3.2.1.10) (see protein)
    28% identity, 90% coverage of query (212 bits)

4mazA The structure of mall mutant enzyme v200s from bacillus subtilus
    29% identity, 90% coverage of query (212 bits)

AAA26939.1 dextran α-1,6-glucosidase (DexB) (EC 3.2.1.70) (see protein)
    29% identity, 92% coverage of query (211 bits)

7lv6B / O06994 The structure of mall mutant enzyme s536r from bacillus subtilis
    29% identity, 90% coverage of query (211 bits)

5brpA / Q65MI2 Crystal structure of bacillus licheniformis trehalose-6-phosphate hydrolase (trea), mutant r201q, in complex with png (see paper)
    27% identity, 99% coverage of query (211 bits)

CAA54266.1 α-glucosidase (EC 3.2.1.20) (see protein)
CAA54266.1 alpha-glucosidase from Bacillus sp. (see paper)
    28% identity, 92% coverage of query (211 bits)

BAE79634.1 dextran α-1,6-glucosidase (DexB;SmDG) (EC 3.2.1.70) (see protein)
    30% identity, 91% coverage of query (210 bits)

AAK28739.1 α-glucosidase (PalZ) (EC 3.2.1.20) (see protein)
    30% identity, 90% coverage of query (209 bits)

O16G2_BACSU / O34364 Probable oligo-1,6-glucosidase 2; Oligosaccharide alpha-1,6-glucosidase 2; Sucrase-isomaltase 2; Isomaltase 2; EC 3.2.1.10 from Bacillus subtilis (strain 168) (see paper)
    28% identity, 92% coverage of query (209 bits)

MAL1_DROME / P07190 Maltase A1; Larval visceral protein H; EC 3.2.1.20 from Drosophila melanogaster (Fruit fly) (see paper)
AAF59089.3 α-glucosidase H (LvpH; RE72980p) (EC 3.2.1.20) (see protein)
    29% identity, 91% coverage of query (209 bits)

CAA02858.1 palatinase / trehalulose hydrolase (MutA) (EC 3.2.1.10|3.2.1.-) (see protein)
    29% identity, 90% coverage of query (209 bits)

5do8B / Q8YAE6 1.8 angstrom crystal structure of listeria monocytogenes lmo0184 alpha-1,6-glucosidase (see paper)
    28% identity, 91% coverage of query (208 bits)

ACE77085.1 oligosaccharide-producing multifunctional amylase (OPMA) (EC 2.4.1.-) (see protein)
    28% identity, 90% coverage of query (208 bits)

3wy4A Crystal structure of alpha-glucosidase mutant e271q in complex with maltose
    31% identity, 92% coverage of query (208 bits)

BAL49684.1 α-glucosidase (AglA;HaG) (EC 3.2.1.20) (see protein)
    30% identity, 92% coverage of query (207 bits)

CAA60858.1 α-glucosidase (Agm2) (EC 3.2.1.20) (see protein)
    29% identity, 89% coverage of query (207 bits)

3wy1A / H3K096 Crystal structure of alpha-glucosidase (see paper)
    30% identity, 92% coverage of query (207 bits)

AAF71997.1 α-glucosidase (EC 3.2.1.20) (see protein)
    28% identity, 93% coverage of query (207 bits)

C1DMP8 isomaltulose synthase (EC 5.4.99.11) from Azotobacter vinelandii (see paper)
    30% identity, 90% coverage of query (207 bits)

3wy2A Crystal structure of alpha-glucosidase in complex with glucose
    30% identity, 92% coverage of query (207 bits)

1wzaA / Q8GPL8 Crystal structure of alpha-amylase from h.Orenii (see paper)
    32% identity, 88% coverage of query (206 bits)

AAN52525.1 α-amylase A (AmyA;Hore_14740) (EC 3.2.1.1) (see protein)
amyA / AAN52525.1 alpha-amylase A from Halothermothrix orenii (see paper)
    32% identity, 88% coverage of query (206 bits)

bsPTRE / BAE45038.1 trehalose-6-phosphate hydrolase from Geobacillus stearothermophilus (see paper)
    27% identity, 93% coverage of query (206 bits)

AAP49335.1 α-amylase (AmyA) (EC 3.2.1.1) (see protein)
    29% identity, 96% coverage of query (205 bits)

ABW98683.1 α-glucosidase / binding-toxin receptor (Agm3;AgAgm3) (EC 3.2.1.20) (see protein)
    31% identity, 92% coverage of query (205 bits)

Q9Z3R8 alpha-glucosidase (EC 3.2.1.20) from Sinorhizobium meliloti (see paper)
    32% identity, 94% coverage of query (204 bits)

Q9F4G4 oligo-1,6-glucosidase (EC 3.2.1.10) from Bacillus subtilis (see paper)
AAG23399.1 oligo-α-1,6-glucosidase (EC 3.2.1.10) (see protein)
    28% identity, 90% coverage of query (204 bits)

ADD81256.1 α-amylase (Aamy1) (EC 3.2.1.20) (see protein)
    32% identity, 82% coverage of query (204 bits)

M1E1F6 isomaltulose synthase (EC 5.4.99.11) from Rhizobium sp. MX-45 (see paper)
    29% identity, 91% coverage of query (204 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory