Searching for up to 100 curated homologs for SM_b20101 FitnessBrowser__Smeli:SM_b20101 (426 a.a.)
Found high-coverage hits (≥70%) to 15 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
lhgO / Q88IT9 (S)-2-hydroxyglutarate oxidase from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see 2 papers)
53% identity, 92% coverage of query (405 bits)
LhgD / b2660 L-2-hydroxyglutarate dehydrogenase (EC 1.1.5.13) from Escherichia coli K-12 substr. MG1655 (see 9 papers)
lhgD / P37339 L-2-hydroxyglutarate dehydrogenase (EC 1.1.5.13) from Escherichia coli (strain K12) (see 7 papers)
LHGD_ECOLI / P37339 L-2-hydroxyglutarate dehydrogenase; L2HG dehydrogenase; L2HG:quinone oxidoreductase; EC 1.1.5.13 from Escherichia coli (strain K12) (see 3 papers)
ygaF / RF|NP_417146 uncharacterized protein ygaF from Escherichia coli K12 (see 2 papers)
52% identity, 92% coverage of query (382 bits)
LHGD_ECOLU / B7N6P4 L-2-hydroxyglutarate dehydrogenase; L2HG dehydrogenase; L2HG:quinone oxidoreductase; EC 1.1.5.13 from Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC) (see paper)
52% identity, 92% coverage of query (381 bits)
LHGD_SALHO / A0A5Y6MCT2 L-2-hydroxyglutarate dehydrogenase; L2HG dehydrogenase; L2HG:quinone oxidoreductase; EC 1.1.5.13 from Salmonella houtenae (see paper)
52% identity, 92% coverage of query (377 bits)
L2HDH_INDAL / S2DJ52 L-2-hydroxyglutarate dehydrogenase; EC 1.1.99.2 from Indibacter alkaliphilus (strain CCUG 57479 / KCTC 22604 / LW1) (see paper)
42% identity, 89% coverage of query (323 bits)
L2HDH_HUMAN / Q9H9P8 L-2-hydroxyglutarate dehydrogenase, mitochondrial; Duranin; EC 1.1.99.2 from Homo sapiens (Human) (see 4 papers)
Q9H9P8 L-2-hydroxyglutarate dehydrogenase (EC 1.1.99.2) from Homo sapiens (see 2 papers)
44% identity, 89% coverage of query (307 bits)
8w78A Structure of drosophila melanogaster l-2-hydroxyglutarate dehydrogenase in complex with fad and 2-oxoglutarate
40% identity, 92% coverage of query (281 bits)
8w7fB / Q9VJ28 Structure of drosophila melanogaster l-2-hydroxyglutarate dehydrogenase bound with fad and a sulfate ion (see paper)
40% identity, 92% coverage of query (276 bits)
L2HDH_ACCRE / A0A011QK89 L-2-hydroxyglutarate dehydrogenase; EC 1.1.99.2 from Accumulibacter regalis (see paper)
32% identity, 84% coverage of query (139 bits)
Build an alignment for SM_b20101 and 9 homologs with ≥ 30% identity
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L2HDH_ARATH / Q9LES4 L-2-hydroxyglutarate dehydrogenase, mitochondrial; EC 1.1.99.2 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
27% identity, 92% coverage of query (121 bits)
GLPO_MYCPN / P75063 Glycerol 3-phosphate oxidase; GlpO; L-alpha-glycerophosphate oxidase; EC 1.1.3.21 from Mycoplasma pneumoniae (strain ATCC 29342 / M129 / Subtype 1) (Mycoplasmoides pneumoniae) (see 3 papers)
4x9mA / P75063 Oxidized l-alpha-glycerophosphate oxidase from mycoplasma pneumoniae with fad bound (see paper)
26% identity, 73% coverage of query (85.1 bits)
mqo / O24913 malate:quinone oxidoreductase (EC 1.1.5.4) from Helicobacter pylori (strain ATCC 700392 / 26695) (see 4 papers)
O24913 malate dehydrogenase (quinone) (EC 1.1.5.4) from Helicobacter pylori (see paper)
24% identity, 89% coverage of query (75.9 bits)
Q5RKL4 dimethylglycine dehydrogenase (EC 1.5.8.4) from Rattus norvegicus (see paper)
25% identity, 73% coverage of query (60.8 bits)
Dmgdh / Q63342 dimethylglycine dehydrogenase, mitochondrial (EC 1.5.8.4) from Rattus norvegicus (see 9 papers)
M2GD_RAT / Q63342 Dimethylglycine dehydrogenase, mitochondrial; ME2GLYDH; EC 1.5.8.4 from Rattus norvegicus (Rat) (see 3 papers)
Q63342 dimethylglycine dehydrogenase (EC 1.5.8.4) from Rattus norvegicus (see 3 papers)
26% identity, 73% coverage of query (60.1 bits)
4pabB / Q63342 Crystal structure of the precursor form of rat dmgdh complexed with tetrahydrofolate (see paper)
26% identity, 73% coverage of query (60.1 bits)
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Lawrence Berkeley National Laboratory