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Searching for up to 100 curated homologs for SM_b20316 FitnessBrowser__Smeli:SM_b20316 (333 a.a.)

Found high-coverage hits (≥70%) to 24 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

H281DRAFT_01114 deoxynucleoside transporter, substrate-binding component from Paraburkholderia bryophila 376MFSha3.1
    63% identity, 96% coverage of query (421 bits)

TC 3.A.1.2.9 / Q7BSH5 RhaS, component of Rhamnose porter (Richardson et al., 2004) (Transport activity is dependent on rhamnokinase (RhaK; AAQ92412) activity (Richardson and Oresnik, 2007) This could be an example of group translocation!) from Rhizobium leguminosarum (biovar trifolii) (see paper)
    31% identity, 85% coverage of query (119 bits)

Build an alignment

Build an alignment for SM_b20316 and 2 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

4pz0A / A0A6H3AKG3 The crystal structure of a solute binding protein from bacillus anthracis str. Ames in complex with quorum-sensing signal autoinducer-2 (ai-2)
    28% identity, 90% coverage of query (99.8 bits)

3c6qC Apo and ligand-bound form of a thermophilic glucose/xylose binding protein
    31% identity, 71% coverage of query (99.0 bits)

2h3hA / Q9WXW9 Crystal structure of the liganded form of thermotoga maritima glucose binding protein (see paper)
    31% identity, 71% coverage of query (97.8 bits)

LSRB_SALTY / Q8ZKQ1 Autoinducer 2-binding protein LsrB; AI-2-binding protein LsrB from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
    26% identity, 98% coverage of query (94.0 bits)

LsrB / b1516 Autoinducer-2 ABC transporter periplasmic binding protein (EC 7.6.2.13) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
LsrB / P76142 Autoinducer-2 ABC transporter periplasmic binding protein (EC 7.6.2.13) from Escherichia coli (strain K12) (see 5 papers)
LSRB_ECOLI / P76142 Autoinducer 2-binding protein LsrB; AI-2-binding protein LsrB from Escherichia coli (strain K12) (see 2 papers)
TC 3.A.1.2.8 / P76142 LsrB(R), component of Autoinducer-2 (AI-2, a furanosyl borate diester: (3aS,6S,6aR)-2,2,6,6a-tetrahydroxy-3a-methyltetrahydrofuro[3,2-d][1,3,2]dioxaborolan-2-uide) uptake porter (Taga et al., 2001, 2003) from Escherichia coli (see 4 papers)
lsrB autoinducer 2 ABC transporter, periplasmic substrate-binding protein LsrB from Escherichia coli K12 (see paper)
    27% identity, 100% coverage of query (89.4 bits)

1tjyA / Q8ZKQ1 Crystal structure of salmonella typhimurium ai-2 receptor lsrb in complex with r-thmf (see paper)
    26% identity, 92% coverage of query (88.6 bits)

6guqA Crystal structure of ganp, a glucose-galactose binding protein from geobacillus stearothermophilus, in complex with glucose
    27% identity, 75% coverage of query (87.0 bits)

6gt9A / W8QN64 Crystal structure of ganp, a glucose-galactose binding protein from geobacillus stearothermophilus, in complex with galactose
    27% identity, 75% coverage of query (86.3 bits)

3t95A / Q74PW2 Crystal structure of lsrb from yersinia pestis complexed with autoinducer-2 (see paper)
    26% identity, 92% coverage of query (84.0 bits)

3ejwA / Q926H7 Crystal structure of the sinorhizobium meliloti ai-2 receptor, smlsrb (see paper)
    26% identity, 91% coverage of query (81.3 bits)

5dteB / A6VKG5 Crystal structure of an abc transporter periplasmic solute binding protein (ipr025997) from actinobacillus succinogenes 130z(asuc_0081, target efi-511065) with bound d-allose
    28% identity, 73% coverage of query (80.5 bits)

AlsB / b4088 D-allose ABC transporter periplasmic binding protein (EC 7.5.2.8) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
AlsB / P39265 D-allose ABC transporter periplasmic binding protein (EC 7.5.2.8) from Escherichia coli (strain K12) (see 5 papers)
ALSB_ECOLI / P39265 D-allose-binding periplasmic protein; ALBP from Escherichia coli (strain K12) (see paper)
P39265 ABC-type D-allose transporter (EC 7.5.2.8) from Escherichia coli (see paper)
TC 3.A.1.2.6 / P39265 AlsB aka B4088, component of D-allose porter from Escherichia coli (see 6 papers)
alsB / GB|AAC77049.1 D-allose-binding periplasmic protein; EC 3.6.3.17 from Escherichia coli K12 (see 6 papers)
    28% identity, 82% coverage of query (79.0 bits)

RALBP_PSEAE / Q9I2F8 D-ribose/D-allose-binding protein from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
    26% identity, 72% coverage of query (69.3 bits)

HSERO_RS05260 ABC transporter for L-fucose, substrate-binding component from Herbaspirillum seropedicae SmR1
    24% identity, 91% coverage of query (67.8 bits)

HSERO_RS11480 D-ribose ABC transporter, substrate-binding component RbsB from Herbaspirillum seropedicae SmR1
    25% identity, 72% coverage of query (62.8 bits)

7e7mC / Q8E283 Crystal structure analysis of the streptococcus agalactiae ribose binding protein rbsb
    24% identity, 77% coverage of query (62.0 bits)

APIBP_ACTSZ / A6VKQ8 D-apiose import binding protein; D-apiose binding SBP from Actinobacillus succinogenes (strain ATCC 55618 / DSM 22257 / CCUG 43843 / 130Z) (see paper)
    24% identity, 73% coverage of query (50.4 bits)

5xssA / A6LW07 Xylfii molecule (see paper)
    21% identity, 78% coverage of query (50.4 bits)

4rxtA / B9JKX8 Crystal structure of carbohydrate transporter solute binding protein arad_9553 from agrobacterium radiobacter, target efi-511541, in complex with d-arabinose
    25% identity, 80% coverage of query (48.5 bits)

THPA_MYCS2 / A0QYB5 D-threitol-binding protein from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see paper)
    24% identity, 76% coverage of query (48.1 bits)

APIBP_RHIR8 / B9JK76 D-apiose import binding protein; D-apiose binding SBP from Rhizobium rhizogenes (strain K84 / ATCC BAA-868) (Agrobacterium radiobacter) (see paper)
    23% identity, 74% coverage of query (46.2 bits)

1dbpA / P02925 Identical mutations at corresponding positions in two homologous proteins with non-identical effects (see paper)
    22% identity, 78% coverage of query (43.1 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory