Searching for up to 100 curated homologs for SM_b20453 FitnessBrowser__Smeli:SM_b20453 (303 a.a.)

Found high-coverage hits (≥70%) to 30 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

dhaL / Q0K7D4 L-dehydro-ascorbate lactonase from Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337) (see 2 papers)
    47% identity, 94% coverage of query (260 bits)

3dr2A / B0RN69 Structural and functional analyses of xc5397 from xanthomonas campestris: a gluconolactonase important in glucose secondary metabolic pathways (see paper)
    42% identity, 91% coverage of query (213 bits)

3e5zA / Q9RXN3 X-ray structure of the putative gluconolactonase in protein family pf08450. Northeast structural genomics consortium target drr130.
    39% identity, 96% coverage of query (205 bits)

gnl / Q01578 gluconolactonase subunit (EC 3.1.1.17) from Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) (see paper)
GNL_ZYMMO / Q01578 Gluconolactonase; D-glucono-delta-lactone lactonohydrolase; EC 3.1.1.17 from Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) (see paper)
Q01578 gluconolactonase (EC 3.1.1.17) from Zymomonas mobilis subsp. mobilis (see paper)
    33% identity, 95% coverage of query (147 bits)

xacC / D4GP31 D-xylono/L-arabinono-1,4-lactonase (EC 3.1.1.15; EC 3.1.1.68) from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (see 5 papers)
XACC_HALVD / D4GP31 Pentonolactonase XacC; L-arabinonolactonase; Xylono-1,4-lactonase; EC 3.1.1.15; EC 3.1.1.68 from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see paper)
D4GP31 L-arabinonolactonase (EC 3.1.1.15); xylono-1,4-lactonase (EC 3.1.1.68) from Haloferax volcanii (see 2 papers)
    30% identity, 84% coverage of query (88.6 bits)

Build an alignment

Build an alignment for SM_b20453 and 5 homologs with ≥ 30% identity

Or download the sequences

Additional hits (identity < 30%)

uxuL / B2UIY8 D-galactaro-1,5-lactonase/D-glucaro-1,5-lactonase from Ralstonia pickettii (strain 12J) (see paper)
    27% identity, 85% coverage of query (77.8 bits)

PS417_17365 galactaro-1,5-lactonase from Pseudomonas simiae WCS417
    28% identity, 88% coverage of query (77.0 bits)

xylC / A0A0H3C6P8 xylono-1,5-lactonase (EC 3.1.1.110) from Caulobacter vibrioides (strain NA1000 / CB15N) (see 2 papers)
XYLC_CAUVC / Q9A9Z1 D-xylonolactone lactonase; Xylono-1,5-lactonase; EC 3.1.1.110 from Caulobacter vibrioides (strain ATCC 19089 / CB15) (Caulobacter crescentus) (see 4 papers)
Q9A9Z1 xylono-1,5-lactonase (EC 3.1.1.110) from Caulobacter vibrioides (see 4 papers)
    28% identity, 90% coverage of query (75.5 bits)

7plbB / Q9A9Z1 Caulobacter crescentus xylonolactonase with d-xylose (see paper)
    28% identity, 90% coverage of query (75.5 bits)

7pldB Caulobacter crescentus xylonolactonase with (r)-4-hydroxy-2- pyrrolidone
    28% identity, 90% coverage of query (75.5 bits)

ORYL_ASPOR / Q2TXF9 Lactonohydrolase oryL; Oryzines biosynthesis cluster protein L; EC 3.1.1.- from Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold) (see paper)
    26% identity, 71% coverage of query (70.9 bits)

PP_1170 D-glucaro-1,5-lactonase UxuL from Pseudomonas putida KT2440
    26% identity, 84% coverage of query (65.9 bits)

8dk0A Crystal structure of rpa3624, a beta-propeller lactonase from rhodopseudomonas palustris, with active-site bound (s)gamma- valerolactone
    25% identity, 84% coverage of query (64.3 bits)

8djzA Crystal structure of rpa3624, a beta-propeller lactonase from rhodopseudomonas palustris, with active-site bound product
    25% identity, 84% coverage of query (64.3 bits)

8djfA Crystal structure of rpa3624, a beta-propeller lactonase from rhodopseudomonas palustris, with active-site bound tetrahedral intermediate
    25% identity, 84% coverage of query (64.3 bits)

Ga0059261_1893 Xylonolactonase (EC 3.1.1.68) from Sphingomonas koreensis DSMZ 15582
    27% identity, 84% coverage of query (62.8 bits)

7risA Crystal structure of rpa3624, a beta-propeller lactonase from rhodopseudomonas palustris, with active-site bound phosphate
    24% identity, 84% coverage of query (62.4 bits)

SGL_PSEPU / P0DOV6 6-deoxy-6-sulfogluconolactonase; 6-deoxy-6-sulfogluconolactone lactonase; SGL lactonase; EC 3.1.1.99 from Pseudomonas putida (Arthrobacter siderocapsulatus) (see paper)
    28% identity, 84% coverage of query (62.0 bits)

7rizA / Q6N3R9 Crystal structure of rpa3624, a beta-propeller lactonase from rhodopseudomonas palustris, with active-site bound 2-hydroxyquinoline (see paper)
    24% identity, 84% coverage of query (60.8 bits)

RGN_XENLA / Q9I922 Regucalcin; RC; Gluconolactonase; GNL; Senescence marker protein 30; SMP-30; xSMP-30; EC 3.1.1.17 from Xenopus laevis (African clawed frog) (see paper)
    25% identity, 84% coverage of query (56.2 bits)

PS417_07255 Deoxyribonolactonase from Pseudomonas simiae WCS417
PS417_07255 / A0A1N7TX40 2-deoxy-ribono-1,5-lactonase from Pseudomonas simiae (see paper)
    25% identity, 83% coverage of query (55.5 bits)

Rgn / Q03336 gluconolactonase (EC 3.1.1.17) from Rattus norvegicus (see 3 papers)
RGN_RAT / Q03336 Regucalcin; RC; Gluconolactonase; GNL; Senescence marker protein 30; SMP-30; EC 3.1.1.17 from Rattus norvegicus (Rat) (see 4 papers)
Q03336 diisopropyl-fluorophosphatase (EC 3.1.8.2) from Rattus norvegicus (see paper)
    25% identity, 85% coverage of query (53.9 bits)

Pf1N1B4_413 L-arabinolactonase (EC 3.1.1.15) from Pseudomonas fluorescens FW300-N1B4
    24% identity, 84% coverage of query (52.8 bits)

BPHYT_RS16915 L-arabinono-1,4-lactonase; galactonolactonase from Burkholderia phytofirmans PsJN
    25% identity, 89% coverage of query (52.4 bits)

AO356_20235 L-arabinolactonase (EC 3.1.1.15) / D-galactonolactonase (EC 3.1.1.25) from Pseudomonas fluorescens FW300-N2C3
    23% identity, 85% coverage of query (49.7 bits)

PS417_11020 L-arabinolactonase (EC 3.1.1.15) from Pseudomonas simiae WCS417
    24% identity, 84% coverage of query (49.3 bits)

Pf6N2E2_5966 L-arabinolactonase (EC 3.1.1.15) from Pseudomonas fluorescens FW300-N2E2
    24% identity, 84% coverage of query (49.3 bits)

RGN_HUMAN / Q15493 Regucalcin; RC; Gluconolactonase; GNL; Senescence marker protein 30; SMP-30; EC 3.1.1.17 from Homo sapiens (Human) (see 2 papers)
Q15493 gluconolactonase (EC 3.1.1.17) from Homo sapiens (see paper)
    24% identity, 86% coverage of query (45.8 bits)

4gncA / Q15493 Human smp30/gnl-1,5-ag complex (see paper)
    24% identity, 86% coverage of query (45.8 bits)

3g4hA Crystal structure of human senescence marker protein-30 (zinc bound)
    24% identity, 86% coverage of query (45.8 bits)

Or start over