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Searching for up to 100 curated homologs for SM_b20499 FitnessBrowser__Smeli:SM_b20499 (577 a.a.)

Found high-coverage hits (≥70%) to 23 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

GlyD / b3426 aerobic glycerol 3-phosphate dehydrogenase (EC 1.1.5.3) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
glpD / P13035 aerobic glycerol 3-phosphate dehydrogenase (EC 1.1.5.3) from Escherichia coli (strain K12) (see 10 papers)
P13035 glycerol-3-phosphate dehydrogenase (EC 1.1.5.3) from Escherichia coli (see paper)
2qcuB / P13035 Crystal structure of glycerol-3-phosphate dehydrogenase from escherichia coli (see paper)
glpD glycerol-3-phosphate dehydrogenase; EC 1.1.5.3 from Escherichia coli K12 (see 6 papers)
glpD / AAA24636.1 glycerophosphate dehydrogenase from Escherichia coli (see paper)
    30% identity, 81% coverage of query (167 bits)

2r46A Crystal structure of escherichia coli glycerol-3-phosphate dehydrogenase in complex with 2-phosphopyruvic acid.
    30% identity, 81% coverage of query (167 bits)

2r45A Crystal structure of escherichia coli glycerol-3-phosphate dehydrogenase in complex with 2-phospho-d-glyceric acid
    30% identity, 81% coverage of query (167 bits)

Build an alignment

Build an alignment for SM_b20499 and 3 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

eryB / Q2YIQ2 D-erythritol 1-phosphate dehydrogenase (EC 1.1.1.402) from Brucella abortus (strain 2308) (see 3 papers)
ERYB_BRUA2 / Q2YIQ2 D-erythritol 1-phosphate dehydrogenase; EC 1.1.1.402 from Brucella abortus (strain 2308) (see 3 papers)
    29% identity, 85% coverage of query (165 bits)

AT3g10370 / Q9SS48 glycerol-3-phosphate dehydrogenase (EC 1.1.5.3) from Arabidopsis thaliana (see paper)
SDP6_ARATH / Q9SS48 Glycerol-3-phosphate dehydrogenase SDP6, mitochondrial; Protein SUGAR-DEPENDENT 6; EC 1.1.5.3 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
    26% identity, 93% coverage of query (161 bits)

Q06B39 glycerol-3-phosphate dehydrogenase (EC 1.1.5.3) from Dunaliella salina (see paper)
    27% identity, 91% coverage of query (160 bits)

glpD glycerol-3-phosphate dehydrogenase; EC 1.1.5.3 from Pseudomonas aeruginosa (see paper)
    29% identity, 83% coverage of query (157 bits)

glpD / Q88NY0 aerobic glycerol-3-phosphate dehydrogenase (EC 1.1.5.3) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see 5 papers)
    30% identity, 83% coverage of query (157 bits)

SMc02520 glycerol-3-phosphate dehydrogenase (EC 1.1.5.3) from Sinorhizobium meliloti 1021
    30% identity, 86% coverage of query (150 bits)

glpD / Q5HPP0 aerobic glycerol-3-phosphate dehydrogenase (EC 1.1.5.3) from Staphylococcus epidermidis (strain ATCC 35984 / RP62A) (see paper)
    26% identity, 98% coverage of query (147 bits)

GPDH_ENCCU / Q8SR40 Probable glycerol-3-phosphate dehydrogenase; GPDH; EC 1.1.5.3 from Encephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite) (see paper)
    25% identity, 96% coverage of query (147 bits)

GUT2 / P32191 glycerol-3-phosphate dehydrogenase (EC 1.1.1.8; EC 1.1.1.94; EC 1.1.5.3) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 23 papers)
GPDM_YEAST / P32191 Glycerol-3-phosphate dehydrogenase, mitochondrial; GPD-M; GPDH-M; EC 1.1.5.3 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 3 papers)
    25% identity, 96% coverage of query (142 bits)

GLPD_BACSU / P18158 Aerobic glycerol-3-phosphate dehydrogenase; EC 1.1.5.3 from Bacillus subtilis (strain 168) (see paper)
    25% identity, 90% coverage of query (140 bits)

glpD / CAA74430.1 glycerol-3-phosphate dehydrogenase from Bacillus subtilis (see 3 papers)
    25% identity, 90% coverage of query (139 bits)

GPD2 / P43304 mitochondrial glycerol-3-phosphate dehydrogenase subunit (EC 1.1.5.3) from Homo sapiens (see 8 papers)
GPDM_HUMAN / P43304 Glycerol-3-phosphate dehydrogenase, mitochondrial; GPD-M; GPDH-M; mitohondrial glycerophosphate dehydrogenase gene; mGDH; mtGPD; EC 1.1.5.3 from Homo sapiens (Human) (see paper)
P43304 glycerol-3-phosphate dehydrogenase (EC 1.1.5.3) from Homo sapiens (see 2 papers)
    25% identity, 94% coverage of query (134 bits)

GUT2 glycerol-3-phosphate dehydrogenase, mitochondrial from Candida albicans (see paper)
    24% identity, 93% coverage of query (132 bits)

Q64521 glycerol-3-phosphate dehydrogenase (EC 1.1.5.3) from Mus musculus (see 3 papers)
    25% identity, 94% coverage of query (129 bits)

P35571 glycerol-3-phosphate dehydrogenase (EC 1.1.5.3) from Rattus norvegicus (see 4 papers)
    26% identity, 94% coverage of query (125 bits)

2rgoA / D0VWP7 Structure of alpha-glycerophosphate oxidase from streptococcus sp.: A template for the mitochondrial alpha-glycerophosphate dehydrogenase (see paper)
    24% identity, 89% coverage of query (110 bits)

3da1A / Q9KDW6 X-ray structure of the glycerol-3-phosphate dehydrogenase from bacillus halodurans complexed with fad. Northeast structural genomics consortium target bhr167.
    22% identity, 90% coverage of query (105 bits)

2rgoB / D0VWP7 Structure of alpha-glycerophosphate oxidase from streptococcus sp.: A template for the mitochondrial alpha-glycerophosphate dehydrogenase (see paper)
    23% identity, 89% coverage of query (104 bits)

Q833L7 glycerol-3-phosphate oxidase (EC 1.1.3.21) from Enterococcus faecalis (see paper)
    23% identity, 88% coverage of query (93.2 bits)

GlpA / b2241 anaerobic glycerol-3-phosphate dehydrogenase subunit A (EC 1.1.5.3) from Escherichia coli K-12 substr. MG1655 (see 10 papers)
glpA / P0A9C0 anaerobic glycerol-3-phosphate dehydrogenase subunit A (EC 1.1.5.3) from Escherichia coli (strain K12) (see 8 papers)
    26% identity, 88% coverage of query (80.9 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory