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Searching for up to 100 curated homologs for SM_b20745 FitnessBrowser__Smeli:SM_b20745 (344 a.a.)

Found high-coverage hits (≥70%) to 86 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

GLNA2_RHILP / Q02154 Glutamine synthetase; GS; Glutamate--ammonia ligase; Glutamine synthetase II; GSII; EC 6.3.1.2 from Rhizobium leguminosarum bv. phaseoli (see 2 papers)
    87% identity, 95% coverage of query (603 bits)

GLNA2_STRVR / P19432 Glutamine synthetase; GS; Glutamate--ammonia ligase; Glutamine synthetase II; GSII; EC 6.3.1.2 from Streptomyces viridochromogenes (see paper)
    48% identity, 99% coverage of query (307 bits)

gln1 / RF|NP_593400.1 glutamate-ammonia ligase Gln1; EC 6.3.1.2 from Schizosaccharomyces pombe (see 2 papers)
    48% identity, 96% coverage of query (290 bits)

Q09179 Glutamine synthetase; GS; Glutamate--ammonia ligase; EC 6.3.1.2 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
    48% identity, 96% coverage of query (290 bits)

Q86ZU6 glutamine synthetase (EC 6.3.1.2) from Tuber borchii (see paper)
    48% identity, 95% coverage of query (289 bits)

GLN1 / P32288 glutamine synthetase subunit (EC 6.3.1.2) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 4 papers)
GLNA_YEAST / P32288 Glutamine synthetase; GS; Glutamate--ammonia ligase; EC 6.3.1.2 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
    46% identity, 95% coverage of query (285 bits)

glnA glutamine synthetase; EC 6.3.1.2 from Emericella nidulans (see paper)
    46% identity, 95% coverage of query (277 bits)

7cprA / P20478 Glutamine synthetase from drosophila (see paper)
    47% identity, 95% coverage of query (276 bits)

CH_124280 putative Glutamine synthetase (Glomerella cingulata) from Magnaporthe grisea 70-15 (see paper)
    47% identity, 95% coverage of query (271 bits)

GLN11_ORYSJ / P14656 Glutamine synthetase cytosolic isozyme 1-1; Glutamate--ammonia ligase GLN1;1; OsGLN1;1; Glutamine synthetase shoot isozyme; OsGS1;1; EC 6.3.1.2 from Oryza sativa subsp. japonica (Rice) (see 9 papers)
P14656 glutamine synthetase (EC 6.3.1.2) from Oryza sativa Japonica Group (see 3 papers)
    44% identity, 96% coverage of query (259 bits)

2d3aA / P38561 Crystal structure of the maize glutamine synthetase complexed with adp and methionine sulfoximine phosphate (see paper)
    44% identity, 96% coverage of query (258 bits)

O04998 glutamine synthetase (EC 6.3.1.2) from Medicago truncatula (see 2 papers)
    44% identity, 96% coverage of query (258 bits)

2d3cA Crystal structure of the maize glutamine synthetase complexed with adp and phosphinothricin phosphate
    44% identity, 96% coverage of query (258 bits)

2d3bA Crystal structure of the maize glutamine synthetase complexed with amppnp and methionine sulfoximine
    44% identity, 96% coverage of query (258 bits)

GLN2 / Q43127 glutamine synthetase, type II (EC 6.3.1.2) from Arabidopsis thaliana (see paper)
GLNA2_ARATH / Q43127 Glutamine synthetase, chloroplastic/mitochondrial; GS2; Glutamate--ammonia ligase; EC 6.3.1.2 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q43127 glutamine synthetase (EC 6.3.1.2) from Arabidopsis thaliana (see 2 papers)
    44% identity, 95% coverage of query (257 bits)

C5IW59 glutamine synthetase (EC 6.3.1.2) from Lolium perenne (see paper)
    45% identity, 96% coverage of query (257 bits)

Q7ZVF2 glutamine synthetase (EC 6.3.1.2) from Danio rerio (see paper)
    43% identity, 96% coverage of query (256 bits)

GLN13_ARATH / Q9LVI8 Glutamine synthetase cytosolic isozyme 1-3; GS1; Glutamate--ammonia ligase GLN1;3; GLN1;3; EC 6.3.1.2 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q9LVI8 glutamine synthetase (EC 6.3.1.2) from Arabidopsis thaliana (see 2 papers)
    44% identity, 96% coverage of query (254 bits)

Q45NB5 glutamine synthetase (EC 6.3.1.2) from Triticum aestivum (see paper)
    44% identity, 96% coverage of query (254 bits)

Q45NB6 glutamine synthetase (EC 6.3.1.2) from Triticum aestivum (see paper)
    45% identity, 96% coverage of query (254 bits)

P38562 glutamine synthetase (EC 6.3.1.2) from Zea mays (see paper)
    43% identity, 96% coverage of query (254 bits)

Q45NB7 glutamine synthetase (EC 6.3.1.2) from Triticum aestivum (see paper)
    45% identity, 96% coverage of query (254 bits)

Q9AXD8 glutamine synthetase (EC 6.3.1.2) from Avicennia marina (see paper)
    45% identity, 96% coverage of query (254 bits)

A8WCU3 glutamine synthetase (EC 6.3.1.2) from Gossypium hirsutum (see paper)
    44% identity, 96% coverage of query (253 bits)

GLN11_ARATH / Q56WN1 Glutamine synthetase cytosolic isozyme 1-1; Glutamate--ammonia ligase GLN1;1; GLN1;1; EC 6.3.1.2 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
Q56WN1 glutamine synthetase (EC 6.3.1.2) from Arabidopsis thaliana (see 3 papers)
    44% identity, 96% coverage of query (253 bits)

Q7T2P7 glutamine synthetase (EC 6.3.1.2) from Danio rerio (see paper)
    43% identity, 95% coverage of query (253 bits)

Q6RUJ2 glutamine synthetase (EC 6.3.1.2) from Triticum aestivum (see paper)
    43% identity, 96% coverage of query (252 bits)

C5IW60 glutamine synthetase (EC 6.3.1.2) from Lolium perenne (see paper)
    44% identity, 96% coverage of query (252 bits)

GLNA_MOUSE / P15105 Glutamine synthetase; GS; Glutamate--ammonia ligase; Palmitoyltransferase GLUL; EC 6.3.1.2; EC 2.3.1.225 from Mus musculus (Mouse) (see 5 papers)
P15105 glutamine synthetase (EC 6.3.1.2) from Mus musculus (see paper)
    43% identity, 96% coverage of query (251 bits)

GLN15_ARATH / Q8GXW5 Glutamine synthetase cytosolic isozyme 1-5; Glutamate--ammonia ligase GLN1;5; GLN1;5; EC 6.3.1.2 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    44% identity, 96% coverage of query (251 bits)

Q6RUJ1 glutamine synthetase (EC 6.3.1.2) from Triticum aestivum (see paper)
    43% identity, 96% coverage of query (251 bits)

P04771 glutamine synthetase (EC 6.3.1.2) from Phaseolus vulgaris (see paper)
    45% identity, 96% coverage of query (251 bits)

Q6RUI9 glutamine synthetase (EC 6.3.1.2) from Triticum aestivum (see paper)
    43% identity, 96% coverage of query (251 bits)

8ecyA / P15103 Cryoem structure of bovine bestrophin-2 and glutamine synthetase complex (see paper)
    43% identity, 96% coverage of query (251 bits)

GLNA_RAT / P09606 Glutamine synthetase; GS; Glutamate--ammonia ligase; Palmitoyltransferase GLUL; EC 6.3.1.2; EC 2.3.1.225 from Rattus norvegicus (Rat) (see 5 papers)
P09606 glutamine synthetase (EC 6.3.1.2) from Rattus norvegicus (see paper)
    43% identity, 96% coverage of query (251 bits)

GLNA_CANLF / Q8HZM5 Glutamine synthetase; GS; Glutamate--ammonia ligase; Palmitoyltransferase GLUL; EC 6.3.1.2; EC 2.3.1.225 from Canis lupus familiaris (Dog) (Canis familiaris) (see paper)
Q8HZM5 glutamine synthetase (EC 6.3.1.2) from Canis lupus familiaris (see paper)
    43% identity, 96% coverage of query (251 bits)

GLNA_CHICK / P16580 Glutamine synthetase; GS; Glutamate decarboxylase; Glutamate--ammonia ligase; p42; EC 6.3.1.2; EC 4.1.1.15 from Gallus gallus (Chicken) (see 4 papers)
    42% identity, 96% coverage of query (251 bits)

Q3L0T9 glutamine synthetase (EC 6.3.1.2) from Cucumis melo (see paper)
    43% identity, 96% coverage of query (251 bits)

GLN1;4 / Q9FMD9 glutamine synthetase (EC 6.3.1.2) from Arabidopsis thaliana (see paper)
GLN14_ARATH / Q9FMD9 Glutamine synthetase cytosolic isozyme 1-4; Glutamate--ammonia ligase GLN1;4; GLN1;4; EC 6.3.1.2 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
Q9FMD9 glutamine synthetase (EC 6.3.1.2) from Arabidopsis thaliana (see paper)
    44% identity, 95% coverage of query (251 bits)

Q1MXG4 glutamine synthetase (EC 6.3.1.2) from Enchytraeus japonensis (see paper)
    43% identity, 96% coverage of query (251 bits)

GLUL / P15104 glutamine synthetase subunit (EC 6.3.1.2) from Homo sapiens (see paper)
GLNA_HUMAN / P15104 Glutamine synthetase; GS; Glutamate--ammonia ligase; Palmitoyltransferase GLUL; EC 6.3.1.2; EC 2.3.1.225 from Homo sapiens (Human) (see 6 papers)
P15104 glutamine synthetase (EC 6.3.1.2) from Homo sapiens (see 3 papers)
    42% identity, 96% coverage of query (251 bits)

2uu7A Crystal structure of apo glutamine synthetase from dog (canis familiaris)
    43% identity, 96% coverage of query (251 bits)

GLN12_ORYSJ / P14654 Glutamine synthetase cytosolic isozyme 1-2; Glutamate--ammonia ligase GLN1;2; OsGLN1;2; Glutamine synthetase root isozyme; OsGS1;2; EC 6.3.1.2 from Oryza sativa subsp. japonica (Rice) (see 7 papers)
P14654 glutamine synthetase (EC 6.3.1.2) from Oryza sativa Japonica Group (see 2 papers)
    43% identity, 96% coverage of query (250 bits)

2qc8A Crystal structure of human glutamine synthetase in complex with adp and methionine sulfoximine phosphate
    42% identity, 96% coverage of query (250 bits)

Q6RUJ0 glutamine synthetase (EC 6.3.1.2) from Triticum aestivum (see paper)
    43% identity, 96% coverage of query (249 bits)

GLNA4_PHAVU / P15102 Glutamine synthetase leaf isozyme, chloroplastic; Glutamate--ammonia ligase; Isozyme delta; EC 6.3.1.2 from Phaseolus vulgaris (Kidney bean) (French bean)
    43% identity, 96% coverage of query (249 bits)

gln1b / CAA06383.1 glutamine synthetase from Pinus sylvestris (see paper)
    44% identity, 96% coverage of query (249 bits)

GLNA_SQUAC / P41320 Glutamine synthetase, mitochondrial; Glutamate--ammonia ligase; EC 6.3.1.2 from Squalus acanthias (Spiny dogfish) (see paper)
    42% identity, 96% coverage of query (249 bits)

O04999 glutamine synthetase (EC 6.3.1.2) from Medicago truncatula (see paper)
    44% identity, 96% coverage of query (248 bits)

GLN13_ORYSJ / Q4W8D0 Glutamine synthetase cytosolic isozyme 1-3; Glutamate--ammonia ligase GLN1;3; OsGLN1;3; OsGS1;3; EC 6.3.1.2 from Oryza sativa subsp. japonica (Rice) (see paper)
Q4W8D0 glutamine synthetase (EC 6.3.1.2) from Oryza sativa Japonica Group (see paper)
    43% identity, 96% coverage of query (248 bits)

GLNA2_ORYSJ / P14655 Glutamine synthetase, chloroplastic; Glutamate--ammonia ligase GLN2; OsGLN2; OsGS2; GS2; EC 6.3.1.2 from Oryza sativa subsp. japonica (Rice) (see paper)
P14655 glutamine synthetase (EC 6.3.1.2) from Oryza sativa (see paper)
    43% identity, 99% coverage of query (248 bits)

P46410 glutamine synthetase (EC 6.3.1.2) from Sus scrofa (see paper)
    42% identity, 96% coverage of query (248 bits)

GLN12_ARATH / Q8LCE1 Glutamine synthetase cytosolic isozyme 1-2; Glutamate--ammonia ligase GLN1;2; GLN1;2; EC 6.3.1.2 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
Q8LCE1 glutamine synthetase (EC 6.3.1.2) from Arabidopsis thaliana (see paper)
    43% identity, 96% coverage of query (248 bits)

Q84UC1 glutamine synthetase (EC 6.3.1.2) from Medicago truncatula (see paper)
    42% identity, 95% coverage of query (244 bits)

P25462 glutamine synthetase (EC 6.3.1.2) from Zea mays (see paper)
    42% identity, 96% coverage of query (243 bits)

Q86EI1 glutamine synthetase (EC 6.3.1.2) from Schistosoma japonicum (see paper)
    44% identity, 96% coverage of query (243 bits)

2ojwA Crystal structure of human glutamine synthetase in complex with adp and phosphate
    41% identity, 96% coverage of query (241 bits)

Q45NB2 glutamine synthetase (EC 6.3.1.2) from Triticum aestivum (see paper)
    42% identity, 96% coverage of query (240 bits)

P13564 glutamine synthetase (EC 6.3.1.2) from Hordeum vulgare (see 2 papers)
    42% identity, 96% coverage of query (239 bits)

Q45NB3 glutamine synthetase (EC 6.3.1.2) from Triticum aestivum (see paper)
    42% identity, 96% coverage of query (238 bits)

Q4CN04 glutamine synthetase (EC 6.3.1.2) from Trypanosoma cruzi (see paper)
    38% identity, 97% coverage of query (232 bits)

Q45NB4 glutamine synthetase (EC 6.3.1.2) from Triticum aestivum (see paper)
    42% identity, 96% coverage of query (232 bits)

E9B8P8 glutamine synthetase (EC 6.3.1.2) from Leishmania donovani (see paper)
    38% identity, 99% coverage of query (231 bits)

Q08CT3 glutamine synthetase (EC 6.3.1.2) from Danio rerio (see paper)
    40% identity, 96% coverage of query (231 bits)

7u5nA / P15103 Cryo-em structure of glutamine synthetase (see paper)
    39% identity, 96% coverage of query (217 bits)

Build an alignment

Build an alignment for SM_b20745 and 65 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

8oozA Glutamine synthetase
    27% identity, 84% coverage of query (67.4 bits)

8ooxB / A0A832VZP6 8ooxB (see paper)
    26% identity, 84% coverage of query (66.6 bits)

7tfaB / A0A0F0G8G2 7tfaB (see paper)
    25% identity, 84% coverage of query (62.8 bits)

7tdpA Structure of paenibacillus polymyxa gs bound to met-sox-p-adp (transition state complex) to 1.98 angstom
    26% identity, 84% coverage of query (61.2 bits)

GLNA_METJA / Q60182 Glutamine synthetase; GS; Glutamate--ammonia ligase; Glutamine synthetase I alpha; GSI alpha; EC 6.3.1.2 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see paper)
Q60182 glutamine synthetase (EC 6.3.1.2) from Methanocaldococcus jannaschii (see paper)
    27% identity, 84% coverage of query (60.8 bits)

GLNA_THET8 / Q5SIP0 Glutamine synthetase; GS; Glutamate--ammonia ligase; EC 6.3.1.2 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see paper)
    25% identity, 82% coverage of query (60.1 bits)

P9WN37 Glutamine synthetase; GS; Glutamate--ammonia ligase; Glutamine synthetase I alpha; GSI alpha; EC 6.3.1.2 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
    28% identity, 84% coverage of query (58.5 bits)

4s0rD / P12425 Structure of gs-tnra complex (see paper)
    26% identity, 84% coverage of query (58.2 bits)

GLN1A_BACSU / P12425 Glutamine synthetase; GS; Glutamate--ammonia ligase; Glutamine synthetase I alpha; GSI alpha; EC 6.3.1.2 from Bacillus subtilis (strain 168) (see 9 papers)
P12425 glutamine synthetase (EC 6.3.1.2) from Bacillus subtilis (see 2 papers)
    25% identity, 84% coverage of query (58.2 bits)

4lnkA B. Subtilis glutamine synthetase structures reveal large active site conformational changes and basis for isoenzyme specific regulation: structure of gs-glutamate-amppcp complex
    25% identity, 84% coverage of query (58.2 bits)

4lniA B. Subtilis glutamine synthetase structures reveal large active site conformational changes and basis for isoenzyme specific regulation: structure of the transition state complex
    25% identity, 84% coverage of query (58.2 bits)

P36687 glutamine synthetase (EC 6.3.1.2) from Pyrococcus woesei (see paper)
    28% identity, 84% coverage of query (56.6 bits)

7tenA Glutamine synthetase
    27% identity, 84% coverage of query (56.6 bits)

7tf9S / A0A5D5GA79 L. Monocytogenes gs(14)-q-glnr peptide (see paper)
    27% identity, 84% coverage of query (56.2 bits)

3ng0A / P77961 Crystal structure of glutamine synthetase from synechocystis sp. Pcc 6803
    27% identity, 84% coverage of query (51.6 bits)

GLN1B_SALTY / P0A1P6 Glutamine synthetase; GS; Glutamate--ammonia ligase; Glutamine synthetase I beta; GSI beta; EC 6.3.1.2 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 4 papers)
P0A1P6 glutamine synthetase (EC 6.3.1.2) from Salmonella enterica subsp. enterica serovar Typhimurium (see paper)
glnA glutamate--ammonia ligase; EC 6.3.1.2 from Salmonella enterica subsp. enterica serovar Typhimurium (see paper)
    26% identity, 84% coverage of query (50.8 bits)

1fpyA Crystal structure of glutamine synthetase from salmonella typhimurium with inhibitor phosphinothricin
    26% identity, 84% coverage of query (50.8 bits)

1f1hA / P0A1P6 Crystal structure of glutamine synthetase from salmonella typhimurium with thallium ions (see paper)
    26% identity, 84% coverage of query (50.8 bits)

7tdvC / E3VXC2 7tdvC (see paper)
    26% identity, 84% coverage of query (50.8 bits)

7tf6A Glutamine synthetase
    26% identity, 84% coverage of query (50.4 bits)

A0R079 Glutamine synthetase; GS; Glutamate--ammonia ligase; Glutamine synthetase I beta; GSI beta; EC 6.3.1.2 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis)
    27% identity, 70% coverage of query (47.4 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory