Searching for up to 100 curated homologs for SM_b20899 FitnessBrowser__Smeli:SM_b20899 (330 a.a.)
Found high-coverage hits (≥70%) to 83 curated proteins.
Removed hits that are identical to the query, leaving 82
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
Q9EZV8 inositol 2-dehydrogenase (EC 1.1.1.18) from Sinorhizobium fredii (see paper)
92% identity, 100% coverage of query (553 bits)
HSERO_RS12095 Myo-inositol 2-dehydrogenase (EC 1.1.1.18) from Herbaspirillum seropedicae SmR1
48% identity, 98% coverage of query (299 bits)
iolG / Q9WYP5 myo-inositol 2-dehydrogenase (EC 1.1.1.18) from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
IOLG_THEMA / Q9WYP5 Myo-inositol 2-dehydrogenase; EC 1.1.1.18 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
Q9WYP5 D-chiro-inositol 1-dehydrogenase (EC 1.1.1.369) from Thermotoga maritima (see paper)
43% identity, 99% coverage of query (271 bits)
iolX / P40332 scyllo-inositol 2-dehydrogenase (NAD+) (EC 1.1.1.370) from Bacillus subtilis (strain 168) (see paper)
IOLX_BACSU / P40332 scyllo-inositol 2-dehydrogenase (NAD(+)); EC 1.1.1.370 from Bacillus subtilis (strain 168) (see paper)
P40332 scyllo-inositol 2-dehydrogenase (NAD+) (EC 1.1.1.370) from Bacillus subtilis (see 2 papers)
38% identity, 96% coverage of query (193 bits)
4n54A / A0A0J9X1Y7 Crystal structure of scyllo-inositol dehydrogenase from lactobacillus casei with bound cofactor NAD(h) and scyllo-inositol
31% identity, 95% coverage of query (163 bits)
E1U888 inositol 2-dehydrogenase (EC 1.1.1.18) from Lacticaseibacillus casei (see paper)
31% identity, 95% coverage of query (161 bits)
mocA / GB|CAA55269.1 rhizopine catabolism protein MocA from Sinorhizobium meliloti (see paper)
31% identity, 95% coverage of query (145 bits)
Build an alignment for SM_b20899 and 7 homologs with ≥ 30% identity
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3ceaA / F9ULF9 Crystal structure of myo-inositol 2-dehydrogenase (np_786804.1) from lactobacillus plantarum at 2.40 a resolution
28% identity, 96% coverage of query (134 bits)
iolG / P26935 inositol 2-dehydrogenase monomer (EC 1.1.1.18; EC 1.1.1.369) from Bacillus subtilis (strain 168) (see 5 papers)
IOLG_BACSU / P26935 Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase; Myo-inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase; MI 2-dehydrogenase/DCI 3-dehydrogenase; EC 1.1.1.18; EC 1.1.1.369 from Bacillus subtilis (strain 168) (see 3 papers)
P26935 inositol 2-dehydrogenase (EC 1.1.1.18); D-chiro-inositol 1-dehydrogenase (EC 1.1.1.369) from Bacillus subtilis (see 7 papers)
28% identity, 97% coverage of query (119 bits)
AO356_23190 Inositol 2-dehydrogenase (EC 1.1.1.18) from Pseudomonas fluorescens FW300-N2C3
30% identity, 93% coverage of query (119 bits)
4l8vA / P26935 Crystal structure of a12k/d35s mutant myo-inositol dehydrogenase from bacillus subtilis with bound cofactor NADP (see paper)
28% identity, 97% coverage of query (119 bits)
3nt5A Crystal structure of myo-inositol dehydrogenase from bacillus subtilis with bound cofactor and product inosose
28% identity, 97% coverage of query (119 bits)
3nt4A Crystal structure of myo-inositol dehydrogenase from bacillus subtilis with bound cofactor nadh and inositol
28% identity, 97% coverage of query (119 bits)
3nt2B Crystal structure of myo-inositol dehydrogenase from bacillus subtilis with bound cofactor
28% identity, 97% coverage of query (119 bits)
3nt2A Crystal structure of myo-inositol dehydrogenase from bacillus subtilis with bound cofactor
28% identity, 97% coverage of query (119 bits)
AO353_21365 Inositol 2-dehydrogenase (EC 1.1.1.18) from Pseudomonas fluorescens FW300-N2E3
30% identity, 93% coverage of query (116 bits)
iolG / A0A0H3FQ94 myo-inositol 2-dehydrogenase (EC 1.1.1.18) from Klebsiella aerogenes (strain ATCC 13048 / DSM 30053 / CCUG 1429 / JCM 1235 / KCTC 2190 / NBRC 13534 / NCIMB 10102 / NCTC 10006 / CDC 819-56) (see 2 papers)
30% identity, 97% coverage of query (115 bits)
PS417_11875 Inositol 2-dehydrogenase (EC 1.1.1.18) from Pseudomonas simiae WCS417
28% identity, 93% coverage of query (114 bits)
BWI76_RS03095 Inositol 2-dehydrogenase (EC 1.1.1.18) from Klebsiella michiganensis M5al
30% identity, 97% coverage of query (114 bits)
3ec7A / Q8ZK57 Crystal structure of putative dehydrogenase from salmonella typhimurium lt2
29% identity, 97% coverage of query (105 bits)
Q92KZ3 1,5-anhydro-D-fructose reductase (EC 1.1.1.263); 1,5-anhydro-D-fructose reductase (1,5-anhydro-D-mannitol-forming) (EC 1.1.1.292) from Sinorhizobium meliloti (see paper)
4koaA / Q92KZ3 Crystal structure analysis of 1,5-anhydro-d-fructose reductase from sinorhizobium meliloti (see paper)
28% identity, 99% coverage of query (101 bits)
8qc8D Crystal structure of NAD-dependent glycoside hydrolase from flavobacterium sp. (Strain k172) in complex with co-factor NAD+ (see paper)
27% identity, 73% coverage of query (100 bits)
6a3iA Levoglucosan dehydrogenase, complex with nadh and levoglucosan
28% identity, 99% coverage of query (100 bits)
8qc2A Crystal structure of NAD-dependent glycoside hydrolase from flavobacterium sp. (Strain k172) in complex with co-factor NAD+ and sulfoquinovose (sq)
27% identity, 73% coverage of query (99.4 bits)
8qc8B Crystal structure of NAD-dependent glycoside hydrolase from flavobacterium sp. (Strain k172) in complex with co-factor NAD+ (see paper)
27% identity, 73% coverage of query (99.0 bits)
5a03C / Q9A8X3 Crystal structure of aldose-aldose oxidoreductase from caulobacter crescentus complexed with xylose (see paper)
26% identity, 92% coverage of query (99.0 bits)
5a06A Crystal structure of aldose-aldose oxidoreductase from caulobacter crescentus complexed with sorbitol
26% identity, 92% coverage of query (99.0 bits)
5a05A Crystal structure of aldose-aldose oxidoreductase from caulobacter crescentus complexed with maltotriose
26% identity, 92% coverage of query (99.0 bits)
5a04A Crystal structure of aldose-aldose oxidoreductase from caulobacter crescentus complexed with glucose
26% identity, 92% coverage of query (99.0 bits)
5a03E Crystal structure of aldose-aldose oxidoreductase from caulobacter crescentus complexed with xylose
26% identity, 92% coverage of query (99.0 bits)
5a02A Crystal structure of aldose-aldose oxidoreductase from caulobacter crescentus complexed with glycerol
26% identity, 92% coverage of query (99.0 bits)
6a3jC / F0M433 Levoglucosan dehydrogenase, complex with nadh and l-sorbose (see paper)
27% identity, 99% coverage of query (98.2 bits)
2glxA / Q2I8V6 Crystal structure analysis of bacterial 1,5-af reductase (see paper)
28% identity, 97% coverage of query (97.8 bits)
APSD_PARG4 / B1G894 D-apiose dehydrogenase; EC 1.1.1.420 from Paraburkholderia graminis (strain ATCC 700544 / DSM 17151 / LMG 18924 / NCIMB 13744 / C4D1M) (see paper)
31% identity, 98% coverage of query (97.8 bits)
A0A064C3N0 1,5-anhydro-D-fructose reductase (1,5-anhydro-D-mannitol-forming) (EC 1.1.1.292) from Streptococcus pneumoniae (see paper)
27% identity, 75% coverage of query (97.4 bits)
afr / Q2I8V6 1,5-anhydro-D-fructose reductase (EC 1.1.1.292) from Ensifer adhaerens (see 3 papers)
AFR_ENSAD / Q2I8V6 1,5-anhydro-D-fructose reductase; Anhydrofructose reductase; 1,5-anhydro-D-fructose reductase (1,5-anhydro-D-mannitol-forming); EC 1.1.1.292 from Ensifer adhaerens (Sinorhizobium morelense) (see 2 papers)
Q2I8V6 1,5-anhydro-D-fructose reductase (1,5-anhydro-D-mannitol-forming) (EC 1.1.1.292) from Ensifer adhaerens (see 2 papers)
28% identity, 97% coverage of query (94.0 bits)
Asphe3_10730 / F0M433 levoglucosan dehydrogenase monomer (EC 1.1.1.425) from Pseudarthrobacter phenanthrenivorans (strain DSM 18606 / JCM 16027 / LMG 23796 / Sphe3) (see 2 papers)
LGDH_PSEPM / F0M433 Levoglucosan dehydrogenase; LGDH; 1,6-anhydro-beta-D-glucose dehydrogenase; PpLGDH; EC 1.1.1.425 from Pseudarthrobacter phenanthrenivorans (strain DSM 18606 / JCM 16027 / LMG 23796 / Sphe3) (Arthrobacter phenanthrenivorans) (see paper)
F0M433 levoglucosan dehydrogenase (EC 1.1.1.425) from Pseudarthrobacter phenanthrenivorans (see paper)
27% identity, 99% coverage of query (93.2 bits)
6o15A / P39353 Crystal structure of a putative oxidoreductase yjhc from escherichia coli in complex with NAD(h) (see paper)
24% identity, 99% coverage of query (92.4 bits)
6z3cAAA / A0A2N5NNS3 6z3cAAA (see paper)
27% identity, 75% coverage of query (91.7 bits)
NanY / b4280 KpLE2 phage-like element; 2,7-anhydro-N-acetylneuraminate hydratase from Escherichia coli K-12 substr. MG1655 (see 4 papers)
nanY / P39353 KpLE2 phage-like element; 2,7-anhydro-N-acetylneuraminate hydratase from Escherichia coli (strain K12) (see 6 papers)
YJHC_ECOLI / P39353 Uncharacterized oxidoreductase YjhC; EC 1.-.-.- from Escherichia coli (strain K12) (see paper)
26% identity, 76% coverage of query (91.3 bits)
Q8NTY7 inositol 2-dehydrogenase (EC 1.1.1.18) from Corynebacterium glutamicum (see paper)
27% identity, 77% coverage of query (90.1 bits)
8qc6A / A0A1C9WRL0 Crystal structure of NAD-dependent glycoside hydrolase from arthrobacter sp. U41 in complex with NAD+ and sulfoquinovose (sq) (see paper)
27% identity, 73% coverage of query (89.4 bits)
orf19.6899 putative uncharacterized protein CaJ7.0133 from Candida albicans (see paper)
24% identity, 98% coverage of query (87.8 bits)
E1U887 inositol 2-dehydrogenase (EC 1.1.1.18) from Lacticaseibacillus casei (see paper)
26% identity, 100% coverage of query (87.4 bits)
4minA / A0A0J9X1Y2 Crystal structure of myo-inositol dehydrogenase from lactobacillus casei with bound cofactor NAD
26% identity, 100% coverage of query (87.0 bits)
4mjlD Crystal structure of myo-inositol dehydrogenase from lactobacillus casei in complex with NAD and d-chiro-inositol
26% identity, 100% coverage of query (87.0 bits)
4mioD Crystal structure of myo-inositol dehydrogenase from lactobacillus casei in complex with NAD(h) and myo-inositol
26% identity, 100% coverage of query (87.0 bits)
4mioA Crystal structure of myo-inositol dehydrogenase from lactobacillus casei in complex with NAD(h) and myo-inositol
26% identity, 100% coverage of query (87.0 bits)
3q2kK / Q79H45 Crystal structure of the wlba dehydrogenase from bordetella pertussis in complex with nadh and udp-glcnaca (see paper)
27% identity, 99% coverage of query (85.9 bits)
6jw7A / Q6L737 The crystal structure of kand2 in complex with nadh and 3"-deamino-3"- hydroxykanamycin a (see paper)
26% identity, 99% coverage of query (84.3 bits)
6jw8A The crystal structure of kand2 in complex with nadh and 3"-deamino-3"- hydroxykanamycin b
26% identity, 99% coverage of query (84.3 bits)
6jw6A The crystal structure of kand2 in complex with NAD
26% identity, 99% coverage of query (84.0 bits)
Q5KYQ3 inositol 2-dehydrogenase (EC 1.1.1.18) from Geobacillus kaustophilus (see paper)
25% identity, 99% coverage of query (80.9 bits)
apsD / B9JK80 D-apiose dehydrogenase (EC 1.1.1.420) from Agrobacterium radiobacter (strain K84 / ATCC BAA-868) (see paper)
APSD_RHIR8 / B9JK80 D-apiose dehydrogenase; EC 1.1.1.420 from Rhizobium rhizogenes (strain K84 / ATCC BAA-868) (Agrobacterium radiobacter) (see paper)
B9JK80 D-apiose dehydrogenase (EC 1.1.1.420) from Agrobacterium tumefaciens (see paper)
26% identity, 98% coverage of query (77.8 bits)
5uhwA / B9JK80 Crystal structure of an oxidoreductase from agrobacterium radiobacter in complex with NAD+ and magnesium
26% identity, 98% coverage of query (77.8 bits)
5uiaA Crystal structure of an oxidoreductase from agrobacterium radiobacter in complex with NAD+, r-2,3-dihydroxyisovalerate and magnesium
26% identity, 98% coverage of query (77.8 bits)
5ui9A Crystal structure of an oxidoreductase from agrobacterium radiobacter in complex with NAD+, 2 -hydroxy-2-hydroxymethyl propanoic acid and magnesium
26% identity, 98% coverage of query (77.8 bits)
5uhzA Crystal structure of an oxidoreductase from agrobacterium radiobacter in complex with NAD+, d-apionate and magnesium
26% identity, 98% coverage of query (77.8 bits)
xacA / D4GP29 D-xylose dehydrogenase subunit (EC 1.1.1.424) from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (see 4 papers)
XDH1_HALVD / D4GP29 D-xylose 1-dehydrogenase [NADP(+)] 1; XDH 1; EC 1.1.1.424 from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see 3 papers)
D4GP29 D-xylose 1-dehydrogenase (NADP+, D-xylono-1,5-lactone-forming) (EC 1.1.1.179); D-xylose 1-dehydrogenase (NADP+, D-xylono-1,4-lactone-forming) (EC 1.1.1.424) from Haloferax volcanii (see 2 papers)
27% identity, 78% coverage of query (74.7 bits)
6norA / Q70KD1 Crystal structure of gend2 from gentamicin a biosynthesis in complex with NAD (see paper)
24% identity, 95% coverage of query (73.2 bits)
UGNO_METMP / Q6M0B9 UDP-N-acetylglucosamine 3-dehydrogenase; UDP-GlcNAc oxidoreductase; UDP-N-acetyl-alpha-D-glucosamine:NAD(+) 3-oxidoreductase; EC 1.1.1.374 from Methanococcus maripaludis (strain S2 / LL) (see paper)
Q6M0B9 UDP-N-acetylglucosamine 3-dehydrogenase (EC 1.1.1.374) from Methanococcus maripaludis (see paper)
23% identity, 96% coverage of query (70.9 bits)
D4GR07 L-arabinose 1-dehydrogenase [NAD(P)+] (EC 1.1.1.376) from Haloferax volcanii (see paper)
26% identity, 86% coverage of query (70.5 bits)
7x2yA / A0A076PYH9 Crystal structure of cis-4,5-dihydrodiol phthalate dehydrogenase in complex with NAD+ and 3-hydroxybenzoate (see paper)
23% identity, 79% coverage of query (68.6 bits)
3q2iA / Q7NQL0 Crystal structure of the wlba dehydrognase from chromobactrium violaceum in complex with nadh and udp-glcnaca at 1.50 a resolution (see paper)
25% identity, 99% coverage of query (67.4 bits)
YdgJ / b1624 putative oxidoreductase YdgJ from Escherichia coli K-12 substr. MG1655 (see 3 papers)
ydgJ / RF|NP_416141 uncharacterized oxidoreductase ydgJ from Escherichia coli K12 (see 2 papers)
27% identity, 83% coverage of query (66.2 bits)
YhhX / b3440 putative oxidoreductase YhhX from Escherichia coli K-12 substr. MG1655 (see 6 papers)
yhhX / RF|NP_417897 uncharacterized oxidoreductase yhhX from Escherichia coli K12 (see 2 papers)
28% identity, 75% coverage of query (65.1 bits)
spnN / Q9ALN5 dTDP-3,4-diketo-2,6-dideoxy-D-glucose 3-ketoreductase (EC 1.1.1.384) from Saccharopolyspora spinosa (see paper)
SPNN_SACSN / Q9ALN5 dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose 3-reductase; dTDP-3,4-diketo-2,6-dideoxy-D-glucose 3-ketoreductase; EC 1.1.1.384 from Saccharopolyspora spinosa (see 2 papers)
Q9ALN5 dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose 3-reductase (EC 1.1.1.384) from Saccharopolyspora spinosa (see paper)
29% identity, 75% coverage of query (64.7 bits)
6ktkC / K7ZP76 Crystal structure of scyllo-inositol dehydrogenase r178a mutant, complexed with nadh and l-glucono-1,5-lactone, from paracoccus laeviglucosivorans (see paper)
28% identity, 75% coverage of query (63.9 bits)
5yaqB Crystal structure of scyllo-inositol dehydrogenase with l-glucose dehydrogenase activity complexed with scyllo-inosose
29% identity, 75% coverage of query (63.9 bits)
5ya8A Crystal structure of scyllo-inositol dehydrogenase with l-glucose dehydrogenase activity complexed with myo-inositol
29% identity, 75% coverage of query (63.9 bits)
slgS4 / CBA11563.1 NDP-hexose-3-ketoreductase from Streptomyces lydicus (see paper)
29% identity, 76% coverage of query (63.5 bits)
1zh8A / Q9WYE8 Crystal structure of oxidoreductase (tm0312) from thermotoga maritima at 2.50 a resolution
24% identity, 99% coverage of query (63.5 bits)
K7ZP76 scyllo-inositol 2-dehydrogenase (NAD+) (EC 1.1.1.370) from Paracoccus laeviglucosivorans (see paper)
lgdA / BAM68195.1 scyllo-inositol dehydrogenase with L-glucose dehydrogenase activity from Paracoccus laeviglucosivorans (see 2 papers)
29% identity, 75% coverage of query (63.2 bits)
3rc1A / B3TMR8 Crystal structure of kijd10, a 3-ketoreductase from actinomadura kijaniata incomplex with NADP and tdp-benzene (see paper)
24% identity, 95% coverage of query (62.4 bits)
KIJDR_ACTKI / B3TMR8 dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose 3-reductase; 3-ketoreductase; NADPH-dependent C3-ketoreductase; EC 1.1.1.384 from Actinomadura kijaniata (see paper)
B3TMR8 dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose 3-reductase (EC 1.1.1.384) from Actinomadura kijaniata (see paper)
24% identity, 95% coverage of query (62.4 bits)
Q9DBB8 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase (EC 1.3.1.20) from Mus musculus (see paper)
25% identity, 82% coverage of query (61.6 bits)
SM_b20330 glucoside 3-dehydrogenase; active on raffinose or trehalose (thuB) (EC 1.1.99.13) from Sinorhizobium meliloti 1021
25% identity, 75% coverage of query (61.2 bits)
XDH_SCHPO / Q9UT60 Probable D-xylose 1-dehydrogenase (NADP(+)); XDH; D-xylose-NADP dehydrogenase; Dimeric dihydrodiol dehydrogenase homolog; NADP(+)-dependent D-xylose dehydrogenase; EC 1.1.1.179 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
22% identity, 80% coverage of query (60.8 bits)
Echvi_3375 predicted 3-ketohexose reductase from Echinicola vietnamensis KMM 6221, DSM 17526
23% identity, 78% coverage of query (58.9 bits)
YgjR / b3087 putative oxidoreductase YgjR from Escherichia coli K-12 substr. MG1655
25% identity, 75% coverage of query (58.9 bits)
3dtyA / Q880Y1 Crystal structure of an oxidoreductase from pseudomonas syringae
25% identity, 81% coverage of query (50.1 bits)
7d5nA Crystal structure of inositol dehydrogenase homolog complexed with nadh and myo-inositol from azotobacter vinelandii
23% identity, 81% coverage of query (48.5 bits)
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Lawrence Berkeley National Laboratory