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Searching for up to 100 curated homologs for SM_b20902 FitnessBrowser__Smeli:SM_b20902 (345 a.a.)

Found high-coverage hits (≥70%) to 42 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

PGA1_262p00430 glucose transporter, periplasmic substrate-binding component from Phaeobacter inhibens BS107
    66% identity, 99% coverage of query (444 bits)

4ywhA / A6VLM7 Crystal structure of an abc transporter solute binding protein (ipr025997) from actinobacillus succinogenes 130z (asuc_0499, target efi-511068) with bound d-xylose
    45% identity, 89% coverage of query (247 bits)

XylT / b3566 xylose ABC transporter periplasmic binding protein (EC 7.5.2.13; EC 7.5.2.10) from Escherichia coli K-12 substr. MG1655 (see 8 papers)
xylF / P37387 xylose ABC transporter periplasmic binding protein (EC 7.5.2.13) from Escherichia coli (strain K12) (see 6 papers)
TC 3.A.1.2.4 / P37387 XylF aka XYLT aka B3566, component of Xylose porter from Escherichia coli (see 5 papers)
xylF / GB|AAC76590.1 D-xylose ABC transporter, periplasmic D-xylose-binding protein from Escherichia coli K12 (see 7 papers)
    44% identity, 91% coverage of query (244 bits)

3ma0A / P37387 Closed liganded crystal structure of xylose binding protein from escherichia coli (see paper)
    43% identity, 90% coverage of query (241 bits)

TC 3.A.1.2.26 / A6LW10 D-xylose ABC transporter, periplasmic substrate-binding protein, component of Xylose transporter, XylFGH (XylF (R), 359 aas; XylG (C), 525 aas; XylH (M), 389 aas from Clostridium beijerinckii (strain ATCC 51743 / NCIMB 8052)
    43% identity, 88% coverage of query (234 bits)

TC 3.A.1.2.24 / O50503 Solute-binding protein, component of XylFGH downstream of characterized transcriptional regulator, ROK7B7 (Sco6008); XylF (Sco6009); XylG (Sco6010); XylH (Sco6011)) from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
    36% identity, 90% coverage of query (163 bits)

TC 3.A.1.2.5 / P25548 CVE1 aka ChvE aka ATU2348 aka AGR_C_4267, component of Multiple sugar (arabinose, xylose, galactose, glucose, fucose) putative porter from Agrobacterium tumefaciens (see 4 papers)
    34% identity, 96% coverage of query (153 bits)

3urmA / P25548 Crystal structure of the periplasmic sugar binding protein chve (see paper)
    33% identity, 88% coverage of query (147 bits)

TC 3.A.1.2.22 / Q8G3R1 Probable sugar binding protein of ABC transporter for pentoses, component of ABC sugar transporter that plays a role in the probiotic benefits through acetate production from Bifidobacterium longum (strain NCC 2705)
    32% identity, 96% coverage of query (147 bits)

3uugA Crystal structure of the periplasmic sugar binding protein chve
    33% identity, 88% coverage of query (147 bits)

chvE / CAC67776.1 sugar-binding protein from Brucella suis (see paper)
    33% identity, 96% coverage of query (145 bits)

4wwhA / A0QT42 Crystal structure of an abc transporter solute binding protein (ipr025997) from mycobacterium smegmatis (msmeg_1704, target efi- 510967) with bound d-galactose
    32% identity, 88% coverage of query (137 bits)

SBPA_AZOBR / P54083 Multiple sugar-binding periplasmic protein SbpA; Sugar-binding protein A from Azospirillum brasilense (see paper)
    30% identity, 94% coverage of query (132 bits)

4ys6A / A9KQP6 Crystal structure of an abc transporter solute binding protein (ipr025997) from clostridium phytofermentans (cphy_1585, target efi- 511156) with bound beta-d-glucose
    31% identity, 89% coverage of query (132 bits)

4rxuA / A9WDY0 Crystal structure of carbohydrate transporter solute binding protein caur_1924 from chloroflexus aurantiacus, target efi-511158, in complex with d-glucose
    33% identity, 89% coverage of query (117 bits)

MglB / b2150 D-galactose/methyl-galactoside ABC transporter periplasmic binding protein from Escherichia coli K-12 substr. MG1655 (see 43 papers)
MglB / P0AEE5 D-galactose/methyl-galactoside ABC transporter periplasmic binding protein from Escherichia coli (strain K12) (see 42 papers)
MGLB_ECOLI / P0AEE5 D-galactose/methyl-galactoside binding periplasmic protein MglB; D-galactose-binding periplasmic protein; GBP; D-galactose/D-glucose-binding protein; GGBP from Escherichia coli (strain K12) (see 3 papers)
TC 3.A.1.2.3 / P0AEE5 D-galactose-binding periplasmic protein DGAL aka MglB aka B2150, component of Galactose/glucose (methyl galactoside) porter from Escherichia coli (see 10 papers)
    31% identity, 81% coverage of query (94.7 bits)

P23905 D-galactose/methyl-galactoside binding periplasmic protein MglB; D-galactose-binding periplasmic protein; GBP; D-galactose/D-glucose-binding protein; GGBP from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
    30% identity, 81% coverage of query (88.2 bits)

2gbpA / P0AEE5 Sugar and signal-transducer binding sites of the escherichia coli galactose chemoreceptor protein (see paper)
    30% identity, 75% coverage of query (87.4 bits)

2qw1A Glucose/galactose binding protein bound to 3-o-methyl d-glucose
    30% identity, 75% coverage of query (87.0 bits)

Build an alignment

Build an alignment for SM_b20902 and 19 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

5kwsA / Q8D072 Crystal structure of galactose binding protein from yersinia pestis in the complex with beta d glucose
    29% identity, 85% coverage of query (84.7 bits)

1gcaA The 1.7 angstroms refined x-ray structure of the periplasmic glucose(slash)galactose receptor from salmonella typhimurium
    30% identity, 75% coverage of query (83.6 bits)

4yo7A / Q9KAG4 Crystal structure of an abc transporter solute binding protein (ipr025997) from bacillus halodurans c-125 (bh2323, target efi- 511484) with bound myo-inositol
    29% identity, 76% coverage of query (82.4 bits)

8fxtA Escherichia coli periplasmic glucose-binding protein glucose complex: acrylodan conjugate attached at w183c
    30% identity, 74% coverage of query (81.6 bits)

4ry9A / A1WJM2 Crystal structure of carbohydrate transporter solute binding protein veis_2079 from verminephrobacter eiseniae ef01-2, target efi-511009, a complex with d-talitol
    26% identity, 85% coverage of query (79.0 bits)

4ry9B Crystal structure of carbohydrate transporter solute binding protein veis_2079 from verminephrobacter eiseniae ef01-2, target efi-511009, a complex with d-talitol
    26% identity, 85% coverage of query (79.0 bits)

PS417_11885 Inositol transport system sugar-binding protein from Pseudomonas simiae WCS417
    29% identity, 83% coverage of query (75.1 bits)

8fxuA / D9TSJ1 Thermoanaerobacter thermosaccharolyticum periplasmic glucose-binding protein glucose complex: badan conjugate attached at f17c (see paper)
    29% identity, 86% coverage of query (74.7 bits)

XYPA_MYCS2 / A0QYB3 Xylitol-binding protein from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see paper)
    28% identity, 76% coverage of query (71.6 bits)

4rs3A / A0QYB3 Crystal structure of carbohydrate transporter a0qyb3 from mycobacterium smegmatis str. Mc2 155, target efi-510969, in complex with xylitol (see paper)
    28% identity, 79% coverage of query (71.6 bits)

5hkoA Crystal structure of abc transporter solute binding protein msmeg_3598 from mycobacterium smegmatis str. Mc2 155, target efi-510969, in complex with l-sorbitol
    28% identity, 79% coverage of query (71.2 bits)

RBSB_BACSU / P36949 Ribose import binding protein RbsB from Bacillus subtilis (strain 168) (see 2 papers)
    29% identity, 76% coverage of query (70.9 bits)

2ioyA / Q8RD41 Crystal structure of thermoanaerobacter tengcongensis ribose binding protein (see paper)
    30% identity, 72% coverage of query (68.2 bits)

TC 3.A.1.2.21 / B8H228 Inositol ABC transporter, periplasmic inositol-binding protein IbpA, component of The myoinositol (high affinity)/ D-ribose (low affinity) transporter IatP/IatA/IbpA. The structure of IbpA with myoinositol bound has been solved from Caulobacter crescentus (strain NA1000 / CB15N)
    29% identity, 75% coverage of query (67.4 bits)

4irxA / A0A0H3C834 Crystal structure of caulobacter myo-inositol binding protein bound to myo-inositol (see paper)
    29% identity, 77% coverage of query (67.0 bits)

THPA_MYCS2 / A0QYB5 D-threitol-binding protein from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see paper)
    28% identity, 78% coverage of query (65.5 bits)

4rsmA / A0QYB5 Crystal structure of carbohydrate transporter msmeg_3599 from mycobacterium smegmatis str. Mc2 155, target efi-510970, in complex with d-threitol (see paper)
    27% identity, 79% coverage of query (65.5 bits)

TC 3.A.1.2.9 / Q7BSH5 RhaS, component of Rhamnose porter (Richardson et al., 2004) (Transport activity is dependent on rhamnokinase (RhaK; AAQ92412) activity (Richardson and Oresnik, 2007) This could be an example of group translocation!) from Rhizobium leguminosarum (biovar trifolii) (see paper)
    28% identity, 83% coverage of query (63.9 bits)

7e7mC / Q8E283 Crystal structure analysis of the streptococcus agalactiae ribose binding protein rbsb
    28% identity, 77% coverage of query (55.1 bits)

BglR / VIMSS6937230 BglR regulator of Beta-glucosides utilization, effector Beta-glucoside (repressor) from Shewanella amazonensis SB2B
    25% identity, 72% coverage of query (54.7 bits)

TC 3.A.1.2.16 / Q1M4Q9 Periplasmic erythritol binding protein, component of The erythritol uptake permease, EryEFG (Yost et al., 2006) (probably orthologous to 3.A.1.2.11) from Rhizobium leguminosarum bv. viciae (strain 3841) (see paper)
    28% identity, 72% coverage of query (46.6 bits)

4y9tA / B9K0Q5 Crystal structure of an abc transporter solute binding protein (ipr025997) from agrobacterium vitis s4 (avi_5305, target efi-511224) with bound alpha-d-glucosamine (see paper)
    28% identity, 73% coverage of query (43.9 bits)

5br1A Crystal structure of an abc transporter solute binding protein (ipr025997) from agrobacterium vitis s4 (avi_5305, target efi-511224) with bound alpha-d-galactosamine
    28% identity, 73% coverage of query (43.9 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory