Searching for up to 100 curated homologs for SM_b20904 FitnessBrowser__Smeli:SM_b20904 (261 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
PGA1_262p00450 glucose transporter, ATPase component from Phaeobacter inhibens BS107
72% identity, 94% coverage of query (360 bits)
TC 3.A.1.2.24 / O50504 Probable ABC-transport system ATP binding protein, component of XylFGH downstream of characterized transcriptional regulator, ROK7B7 (Sco6008); XylF (Sco6009); XylG (Sco6010); XylH (Sco6011)) from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
44% identity, 91% coverage of query (211 bits)
FRCA_RHIML / Q9F9B0 Fructose import ATP-binding protein FrcA; EC 7.5.2.- from Rhizobium meliloti (Ensifer meliloti) (Sinorhizobium meliloti) (see paper)
TC 3.A.1.2.7 / Q9F9B0 FrcA, component of Fructose/mannose/ribose porter from Rhizobium meliloti (Sinorhizobium meliloti) (see paper)
41% identity, 93% coverage of query (202 bits)
HSERO_RS03640 D-mannose ABC transporter, ATPase component from Herbaspirillum seropedicae SmR1
42% identity, 92% coverage of query (199 bits)
HSERO_RS05250 ABC transporter for L-fucose, ATPase component from Herbaspirillum seropedicae SmR1
40% identity, 91% coverage of query (192 bits)
TC 3.A.1.2.19 / Q9X051 Ribose import ATP-binding protein RbsA 2, component of D-ribose porter (Nanavati et al., 2006). Induced by ribose from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
40% identity, 92% coverage of query (189 bits)
FRUK_BIFLO / Q8G847 Fructose import ATP-binding protein FruK; EC 7.5.2.- from Bifidobacterium longum (strain NCC 2705) (see paper)
37% identity, 92% coverage of query (188 bits)
TC 3.A.1.2.13 / A6VKS8 RbsA, component of The probable autoinducer-2 (AI-2;, a furanosyl borate diester: 3aS,6S,6aR)-2,2,6,6a-tetrahydroxy-3a-methyltetrahydrofuro[3,2-d][1,3,2]dioxaborolan-2-uide) uptake porter (Shao et al., 2007) (50-70% identical to RbsABC of E. coli; TC# 3.A.1.2.1) from Actinobacillus succinogenes (strain ATCC 55618 / 130Z)
39% identity, 90% coverage of query (188 bits)
XYLG_SULAC / P0DTT6 Xylose/arabinose import ATP-binding protein XylG; EC 7.5.2.13 from Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770) (see paper)
41% identity, 93% coverage of query (186 bits)
RR42_RS03360 fructose ABC transporter, ATPase component (FrcA) from Cupriavidus basilensis FW507-4G11
42% identity, 93% coverage of query (179 bits)
RbsA / b3749 ribose ABC transporter ATP binding subunit from Escherichia coli K-12 substr. MG1655 (see 5 papers)
RbsA / P04983 ribose ABC transporter ATP binding subunit from Escherichia coli (strain K12) (see 2 papers)
RBSA_ECOLI / P04983 Ribose import ATP-binding protein RbsA; EC 7.5.2.7 from Escherichia coli (strain K12) (see 3 papers)
TC 3.A.1.2.1 / P04983 RbsA aka B3749, component of Ribose porter from Escherichia coli (see 6 papers)
rbsA / GB|AAC76772.1 ribose transport, ATP-binding protein RbsA; EC 3.6.3.17 from Escherichia coli K12 (see 7 papers)
36% identity, 97% coverage of query (177 bits)
PGA1_c07320 Inositol transport system ATP-binding protein from Phaeobacter inhibens BS107
38% identity, 92% coverage of query (177 bits)
TC 3.A.1.2.20 / G4FGN3 Monosaccharide-transporting ATPase, component of Glucose porter. Also bind xylose (Boucher and Noll 2011). Induced by glucose (Frock et al. 2012). Directly regulated by glucose-responsive regulator GluR from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
38% identity, 91% coverage of query (177 bits)
Shewana3_2074 L-arabinose ABC transporter, ATPase component AraV from Shewanella sp. ANA-3
39% identity, 89% coverage of query (175 bits)
PS417_11890 Inositol transport system ATP-binding protein from Pseudomonas simiae WCS417
39% identity, 90% coverage of query (174 bits)
AO353_21385 m-Inositol ABC transporter, ATPase component (itaA) from Pseudomonas fluorescens FW300-N2E3
38% identity, 90% coverage of query (170 bits)
YtfR / b4485 galactofuranose ABC transporter putative ATP binding subunit (EC 7.5.2.9) from Escherichia coli K-12 substr. MG1655 (see paper)
ytfR / Q6BEX0 galactofuranose ABC transporter putative ATP binding subunit (EC 7.5.2.9) from Escherichia coli (strain K12) (see paper)
37% identity, 93% coverage of query (168 bits)
Q6VMN4 ABC-type D-xylose transporter (EC 7.5.2.10) from Thermoanaerobacter ethanolicus (see paper)
35% identity, 95% coverage of query (162 bits)
TC 3.A.1.2.9 / Q7BSH4 RhaT, component of Rhamnose porter (Richardson et al., 2004) (Transport activity is dependent on rhamnokinase (RhaK; AAQ92412) activity (Richardson and Oresnik, 2007) This could be an example of group translocation!) from Rhizobium leguminosarum (biovar trifolii)
37% identity, 95% coverage of query (160 bits)
AlsA / b4087 D-allose ABC transporter ATP binding subunit (EC 7.5.2.8) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
AlsA / P32721 D-allose ABC transporter ATP binding subunit (EC 7.5.2.8) from Escherichia coli (strain K12) (see 2 papers)
ALSA_ECOLI / P32721 D-allose import ATP-binding protein AlsA; EC 7.5.2.8 from Escherichia coli (strain K12) (see paper)
TC 3.A.1.2.6 / P32721 AlsA aka B4087, component of D-allose porter from Escherichia coli (see 5 papers)
alsA / GB|AAC77048.1 D-allose import ATP-binding protein AlsA; EC 3.6.3.17 from Escherichia coli K12 (see 5 papers)
36% identity, 91% coverage of query (156 bits)
eryE / Q2YIY4 putative erythritol ABC transporter ATP-binding protein from Brucella abortus (strain 2308) (see 3 papers)
37% identity, 85% coverage of query (155 bits)
XylG / b3567 xylose ABC transporter ATP binding subunit (EC 7.5.2.13; EC 7.5.2.10) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
XylG / P37388 xylose ABC transporter ATP binding subunit (EC 7.5.2.13) from Escherichia coli (strain K12) (see 2 papers)
XYLG_ECOLI / P37388 Xylose import ATP-binding protein XylG; EC 7.5.2.10 from Escherichia coli (strain K12) (see paper)
TC 3.A.1.2.4 / P37388 XylG aka B3567, component of Xylose porter from Escherichia coli (see 4 papers)
xylG / GB|AAC76591.1 D-xylose ABC transporter, ATP-binding protein; EC 3.6.3.17 from Escherichia coli K12 (see 2 papers)
35% identity, 90% coverage of query (155 bits)
TC 3.A.1.2.10 / O83341 Ribose/galactose ABC transporter, ATP-binding protein aka RbsA-2, component of The purine nucleoside permease (probably transports guanosine, adenosine, 2'-deoxyguanosine, inosine and xanthosine with decreasing affinity in this order) from Treponema pallidum (see paper)
34% identity, 94% coverage of query (155 bits)
Q73KK2 ABC-type D-galactose transporter (EC 7.5.2.11) from Treponema denticola (see paper)
32% identity, 94% coverage of query (153 bits)
PS417_12065 xylitol ABC transporter, ATPase component from Pseudomonas simiae WCS417
36% identity, 92% coverage of query (152 bits)
TC 3.A.1.2.11 / Q92WK2 EryE aka RB0337, component of The erythritol permease, EryEFG (Geddes et al., 2010) (probably orthologous to 3.A.1.2.16) from Rhizobium meliloti (Sinorhizobium meliloti) (see paper)
37% identity, 90% coverage of query (152 bits)
TC 3.A.1.2.16 / Q1M4Q7 ATP binding component of erythritol ABC transporter, component of The erythritol uptake permease, EryEFG (Yost et al., 2006) (probably orthologous to 3.A.1.2.11) from Rhizobium leguminosarum bv. viciae (strain 3841) (see paper)
37% identity, 85% coverage of query (149 bits)
MglA / b2149 D-galactose/methyl-galactoside ABC transporter ATP binding subunit from Escherichia coli K-12 substr. MG1655 (see 6 papers)
MglA / P0AAG8 D-galactose/methyl-galactoside ABC transporter ATP binding subunit from Escherichia coli (strain K12) (see 4 papers)
TC 3.A.1.2.3 / P0AAG8 Galactose/methyl galactoside import ATP-binding protein MglA aka B2149, component of Galactose/glucose (methyl galactoside) porter from Escherichia coli (see 7 papers)
33% identity, 93% coverage of query (149 bits)
MGLA_SALTY / P23924 Galactose/methyl galactoside import ATP-binding protein MglA; EC 7.5.2.11 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 2 papers)
33% identity, 90% coverage of query (149 bits)
TC 3.A.1.2.21 / B8H229 Inositol transport ATP-binding protein IatA, component of The myoinositol (high affinity)/ D-ribose (low affinity) transporter IatP/IatA/IbpA. The structure of IbpA with myoinositol bound has been solved from Caulobacter crescentus (strain NA1000 / CB15N)
37% identity, 90% coverage of query (147 bits)
AraG / b1900 arabinose ABC transporter ATP binding subunit (EC 7.5.2.13; EC 7.5.2.12) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
AraG / P0AAF3 arabinose ABC transporter ATP binding subunit (EC 7.5.2.13) from Escherichia coli (strain K12) (see paper)
ARAG_ECOLI / P0AAF3 Arabinose import ATP-binding protein AraG; EC 7.5.2.12 from Escherichia coli (strain K12) (see 2 papers)
TC 3.A.1.2.2 / P0AAF3 Arabinose import ATP-binding protein AraG aka B1900, component of Arabinose porter from Escherichia coli (see 6 papers)
araG / RF|NP_416413.1 L-arabinose ABC transporter, ATP-binding protein AraG; EC 3.6.3.17 from Escherichia coli K12 (see paper)
37% identity, 85% coverage of query (145 bits)
NUPO_BACSU / O05253 Guanosine import ATP-binding protein NupO; EC 7.6.2.- from Bacillus subtilis (strain 168) (see paper)
34% identity, 97% coverage of query (141 bits)
TSGDD_HALVD / D4GPW3 Glucose import ATP-binding protein TsgD13; EC 7.5.2.- from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see paper)
34% identity, 92% coverage of query (135 bits)
BPHYT_RS34245 ABC transporter for L-rhamnose/L-fucose/xylitol, ATPase component from Burkholderia phytofirmans PsJN
36% identity, 83% coverage of query (134 bits)
LSRA_SALTY / Q8ZKQ4 Autoinducer 2 import ATP-binding protein LsrA; AI-2 import ATP-binding protein LsrA; EC 7.6.2.13 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
34% identity, 91% coverage of query (130 bits)
TC 3.A.1.2.26 / A6LW11 Xylose import ATP-binding protein XylG, component of Xylose transporter, XylFGH (XylF (R), 359 aas; XylG (C), 525 aas; XylH (M), 389 aas from Clostridium beijerinckii (strain ATCC 51743 / NCIMB 8052)
31% identity, 90% coverage of query (129 bits)
Build an alignment for SM_b20904 and 36 homologs with ≥ 30% identity
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4u00A / Q5SJ55 Crystal structure of ttha1159 in complex with adp (see paper)
29% identity, 87% coverage of query (112 bits)
1g6hA / Q58663 Crystal structure of the adp conformation of mj1267, an atp-binding cassette of an abc transporter (see paper)
29% identity, 88% coverage of query (107 bits)
1g9xB Characterization of the twinning structure of mj1267, an atp-binding cassette of an abc transporter
29% identity, 88% coverage of query (106 bits)
3c4jA Abc protein artp in complex with atp-gamma-s
29% identity, 87% coverage of query (106 bits)
3c41J / D0VWX4 Abc protein artp in complex with amp-pnp/mg2+
29% identity, 87% coverage of query (106 bits)
2olkA Abc protein artp in complex with adp-beta-s
29% identity, 87% coverage of query (106 bits)
2oljA Abc protein artp in complex with adp/mg2+
29% identity, 87% coverage of query (106 bits)
PotA / b1126 spermidine preferential ABC transporter ATP binding subunit (EC 7.6.2.11; EC 7.6.2.16) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
PotA / P69874 spermidine preferential ABC transporter ATP binding subunit (EC 7.6.2.11) from Escherichia coli (strain K12) (see 5 papers)
POTA_ECOLI / P69874 Spermidine/putrescine import ATP-binding protein PotA; EC 7.6.2.11 from Escherichia coli (strain K12) (see 6 papers)
TC 3.A.1.11.1 / P69874 Spermidine/putrescine import ATP-binding protein PotA aka B1126, component of Polyamine (putrescine/spermidine) uptake porter from Escherichia coli (see 9 papers)
potA / MB|P69874 spermidine/putrescine ABC transporter, ATP-binding protein PotA; EC 3.6.3.31 from Escherichia coli K12 (see 10 papers)
31% identity, 84% coverage of query (104 bits)
5x40A / O68106 Structure of a cbio dimer bound with amppcp (see paper)
32% identity, 89% coverage of query (102 bits)
Q8TTZ3 ABC-type molybdate transporter (EC 7.3.2.5) from Methanosarcina acetivorans (see paper)
3d31A / Q8TTZ3 Modbc from methanosarcina acetivorans (see paper)
28% identity, 90% coverage of query (102 bits)
6s8nB Cryo-em structure of lptb2fgc in complex with lipopolysaccharide
27% identity, 90% coverage of query (101 bits)
6s8gA Cryo-em structure of lptb2fgc in complex with amp-pnp
27% identity, 90% coverage of query (101 bits)
6mhzA Vanadate trapped cryo-em structure of e.Coli lptb2fg transporter
27% identity, 90% coverage of query (101 bits)
6mbnA / P0A9V1 Lptb e163q in complex with atp (see paper)
26% identity, 90% coverage of query (100 bits)
4yerA / Q9X1C3 Crystal structure of an abc transporter atp-binding protein (tm_1403) from thermotoga maritima msb8 at 2.35 a resolution
30% identity, 84% coverage of query (100 bits)
6b8bA E. Coli lptb in complex with adp and a novobiocin derivative
27% identity, 87% coverage of query (99.8 bits)
6b89A E. Coli lptb in complex with adp and novobiocin
27% identity, 87% coverage of query (99.8 bits)
4p31A Crystal structure of a selenomethionine derivative of e. Coli lptb in complex with adp-magensium
27% identity, 87% coverage of query (99.8 bits)
1ji0A / Q9X0M3 Crystal structure analysis of the abc transporter from thermotoga maritima
27% identity, 89% coverage of query (98.6 bits)
1oxvD Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus
30% identity, 87% coverage of query (98.6 bits)
1oxvA Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus
30% identity, 87% coverage of query (98.6 bits)
GLCV_SACS2 / Q97UY8 Glucose import ATP-binding protein GlcV; EC 7.5.2.- from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see 3 papers)
TC 3.A.1.1.13 / Q97UY8 GlcV, component of Glucose, mannose, galactose porter from Sulfolobus solfataricus (see 3 papers)
1oxuA / Q97UY8 Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus (see paper)
30% identity, 87% coverage of query (98.6 bits)
FhuC / b0151 iron(III) hydroxamate ABC transporter ATP binding subunit (EC 7.2.2.16) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
FhuC / P07821 iron(III) hydroxamate ABC transporter ATP binding subunit (EC 7.2.2.16) from Escherichia coli (strain K12) (see paper)
FHUC_ECOLI / P07821 Iron(3+)-hydroxamate import ATP-binding protein FhuC; Ferric hydroxamate uptake protein C; Ferrichrome transport ATP-binding protein FhuC; Iron(III)-hydroxamate import ATP-binding protein FhuC; EC 7.2.2.16 from Escherichia coli (strain K12) (see 3 papers)
TC 3.A.1.14.3 / P07821 FhuC aka B0151, component of Iron (Fe3+)-hydroxamate (ferrichrome, coprogen, aerobactin, ferrioxamine B, schizakinen, rhodotorulic acid) porter, albomycin porter from Escherichia coli (see 6 papers)
fhuC / GB|BAB96727.2 ferrichrome transport ATP-binding protein FhuC; EC 3.6.3.34 from Escherichia coli K12 (see 8 papers)
31% identity, 94% coverage of query (98.2 bits)
4ymuJ / Q8RCC2 Crystal structure of an amino acid abc transporter complex with arginines and atps (see paper)
26% identity, 87% coverage of query (97.8 bits)
P0AAH0 Phosphate import ATP-binding protein PstB; ABC phosphate transporter; Phosphate-transporting ATPase; EC 7.3.2.1 from Escherichia coli (strain K12)
25% identity, 89% coverage of query (97.8 bits)
6mjpA / O30650 Lptb(e163q)fgc from vibrio cholerae (see paper)
24% identity, 92% coverage of query (97.1 bits)
MALK_SALTY / P19566 Maltose/maltodextrin import ATP-binding protein MalK; EC 7.5.2.1 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
31% identity, 83% coverage of query (97.1 bits)
4hluC / Q9X1Z1 Structure of the ecfa-a' heterodimer bound to adp (see paper)
28% identity, 88% coverage of query (94.4 bits)
2d62A / O57933 Crystal structure of multiple sugar binding transport atp- binding protein
29% identity, 83% coverage of query (94.0 bits)
4zirB Crystal structure of ecfaa' heterodimer bound to amppnp
28% identity, 88% coverage of query (94.0 bits)
5lilA / Q2EHL8 Structure of aggregatibacter actinomycetemcomitans macb bound to atpys (p21) (see paper)
28% identity, 87% coverage of query (93.6 bits)
5lj7A / Q2EHL8 Structure of aggregatibacter actinomycetemcomitans macb bound to atp (p21) (see paper)
28% identity, 87% coverage of query (93.2 bits)
MalK / b4035 maltose ABC transporter ATP binding subunit (EC 7.5.2.1) from Escherichia coli K-12 substr. MG1655 (see 31 papers)
MalK / P68187 maltose ABC transporter ATP binding subunit (EC 7.5.2.1) from Escherichia coli (strain K12) (see 29 papers)
MALK_ECOLI / P68187 Maltose/maltodextrin import ATP-binding protein MalK; EC 7.5.2.1 from Escherichia coli (strain K12) (see 6 papers)
P68187 ABC-type maltose transporter (subunit 3/3) (EC 7.5.2.1) from Escherichia coli (see paper)
TC 3.A.1.1.1 / P68187 Maltose/maltodextrin import ATP-binding protein MalK aka B4035, component of Maltooligosaccharide porter. The 3-D structure has been reported by Oldham et al. (2007). An altering access mechanism has been suggested for the maltose transporter resulting from rigid-body rotations (Khare et al., 2009). Bordignon et al. (2010) and Schneider et al. (2012) have reviewed the extensive knowledge available on MalEFGK2, its mode of action and its regulatory interactions from Escherichia coli (see 17 papers)
malK / RF|NP_418459 maltose/maltodextrin import ATP-binding protein malK; EC 3.6.3.19 from Escherichia coli K12 (see 18 papers)
30% identity, 83% coverage of query (92.4 bits)
2awnB / P68187 Crystal structure of the adp-mg-bound e. Coli malk (crystallized with atp-mg) (see paper)
30% identity, 83% coverage of query (92.4 bits)
3puyA Crystal structure of an outward-facing mbp-maltose transporter complex bound to amp-pnp after crystal soaking of the pretranslocation state
30% identity, 83% coverage of query (92.4 bits)
3puxA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-bef3
30% identity, 83% coverage of query (92.4 bits)
3puwA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-alf4
30% identity, 83% coverage of query (92.4 bits)
3puvA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-vo4
30% identity, 83% coverage of query (92.4 bits)
1q12A Crystal structure of the atp-bound e. Coli malk
30% identity, 83% coverage of query (92.4 bits)
MetN / b0199 L-methionine/D-methionine ABC transporter ATP binding subunit (EC 7.4.2.11) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
MetN / P30750 L-methionine/D-methionine ABC transporter ATP binding subunit (EC 7.4.2.11) from Escherichia coli (strain K12) (see 3 papers)
METN_ECOLI / P30750 Methionine import ATP-binding protein MetN; EC 7.4.2.11 from Escherichia coli (strain K12) (see 7 papers)
P30750 ABC-type methionine transporter (subunit 2/2) (EC 7.4.2.11) from Escherichia coli (see 3 papers)
TC 3.A.1.24.1 / P30750 MetN, D-methionine transport ATP-binding protein, component of The L- and D-methionine porter (also transports formyl-L-methionine and other methionine derivatives) (Zhang et al., 2003). The 3.7A structure of MetNI has been solved. An allosteric regulatory mechanism operates at the level of transport activity, so increased intracellular levels of the transported ligand stabilize an inward-facing, ATPase-inactive state of MetNI to inhibit further ligand translocation into the cell from Escherichia coli (see 5 papers)
30% identity, 84% coverage of query (92.0 bits)
6cvlD / P30750 Crystal structure of the escherichia coli atpgs-bound metni methionine abc transporter in complex with its metq binding protein (see paper)
30% identity, 84% coverage of query (90.9 bits)
3tuzC Inward facing conformations of the metni methionine abc transporter: cy5 semet soak crystal form
30% identity, 84% coverage of query (90.9 bits)
3tuiC Inward facing conformations of the metni methionine abc transporter: cy5 native crystal form
30% identity, 84% coverage of query (90.9 bits)
MacB / b0879 ABC-type tripartite efflux pump ATP binding/membrane subunit from Escherichia coli K-12 substr. MG1655 (see 14 papers)
MacB / P75831 ABC-type tripartite efflux pump ATP binding/membrane subunit from Escherichia coli (strain K12) (see 16 papers)
MACB_ECOLI / P75831 Macrolide export ATP-binding/permease protein MacB; EC 7.6.2.- from Escherichia coli (strain K12) (see 5 papers)
TC 3.A.1.122.1 / P75831 MacB aka B0879, component of Macrolide (14- and 15- but not 16-membered lactone macrolides including erythromycin) exporter, MacAB (formerly YbjYZ). Both MacA and MacB are required for activity (Tikhonova et al., 2007). MacAB functions with TolC to export multiple drugs and heat-stable enterotoxin II (enterotoxin STII) (Yamanaka et al., 2008). The crystal structure of MacA is available (Yum et al., 2009). MacB is a dimer whose ATPase activity and macrolide-binding capacity are regulated by the membrane fusion protein MacA (Lin et al., 2009). Xu et al. (2009) have reported the crystal structure of the periplasmic region of MacB which they claim resembles the periplasmic domain of RND-type transporters such as AcrB (TC# 2.A.6.2.2). Also exports L-cysteine (Yamada et al., 2006). The periplasmic membrane proximal domain of MacA acts as a switch in stimulation of ATP hydrolysis by the MacB transporter from Escherichia coli (see 5 papers)
macB / BAB64542.1 macrolide-specific ABC-type efflux carrier from Escherichia coli (see paper)
29% identity, 84% coverage of query (90.5 bits)
4zirA Crystal structure of ecfaa' heterodimer bound to amppnp
33% identity, 78% coverage of query (89.4 bits)
1vciA / O57758 Crystal structure of the atp-binding cassette of multisugar transporter from pyrococcus horikoshii ot3 complexed with atp (see paper)
27% identity, 83% coverage of query (89.0 bits)
7w78A / Q6NEF2 Heme exporter hrtba in complex with mg-amppnp (see paper)
29% identity, 84% coverage of query (88.6 bits)
7z15I / P16678 E. Coli c-p lyase bound to a phnk/phnl dual abc dimer and adp + pi (see paper)
27% identity, 88% coverage of query (88.6 bits)
7w79A Heme exporter hrtba in complex with mn-amppnp
29% identity, 84% coverage of query (88.6 bits)
7z18I E. Coli c-p lyase bound to a phnk abc dimer and atp
27% identity, 88% coverage of query (88.6 bits)
7chaI / Q9HVW1 Cryo-em structure of p.Aeruginosa mlafebd with amppnp (see paper)
29% identity, 87% coverage of query (88.2 bits)
4hluA / Q9WY65 Structure of the ecfa-a' heterodimer bound to adp (see paper)
31% identity, 78% coverage of query (87.8 bits)
7ph2A Nanodisc reconstituted msba in complex with nanobodies, spin-labeled at position a60c
28% identity, 89% coverage of query (87.8 bits)
MsbA / b0914 ATP-binding lipopolysaccharide transport protein (EC 7.5.2.6) from Escherichia coli K-12 substr. MG1655 (see 54 papers)
msbA / P60752 ATP-binding lipopolysaccharide transport protein (EC 7.5.2.6) from Escherichia coli (strain K12) (see 57 papers)
MSBA_ECOLI / P60752 ATP-dependent lipid A-core flippase; Lipid A export ATP-binding/permease protein MsbA; Lipid flippase; EC 7.5.2.6 from Escherichia coli (strain K12) (see 17 papers)
P60752 ABC-type lipid A-core oligosaccharide transporter (EC 7.5.2.6); P-type phospholipid transporter (EC 7.6.2.1) from Escherichia coli (see 13 papers)
TC 3.A.1.106.1 / P60752 Phospholipid, LPS, lipid A and drug exporter, MsbA, which flips the substrate from the inner leaflet of the cytoplasmic membrane to the outer leaflet (Eckford and Sharom, 2010). MsbA also confers drug resistance to azidopine, daunomycin, vinblastine, Hoechst 33342 and ethidium (Reuter et al., 2003). Four x-ray structures, trapped in different conformations, two with and two without nucleotide, have been solved (Ward et al., 2007). They suggest an alternating accessibility mode of transport with major conformational changes from Escherichia coli (see 11 papers)
msbA / MB|P60752 lipid A export ATP-binding/permease protein msbA; EC 3.6.3.- from Escherichia coli K12 (see 24 papers)
28% identity, 89% coverage of query (87.8 bits)
7bcwA Structure of msba in salipro with adp vanadate
28% identity, 89% coverage of query (87.8 bits)
7ph3A / P60752 Amp-pnp bound nanodisc reconstituted msba with nanobodies, spin- labeled at position a60c (see paper)
28% identity, 89% coverage of query (87.8 bits)
8dmmA Structure of the vanadate-trapped msba bound to kdl
28% identity, 89% coverage of query (87.4 bits)
7mewA E. Coli msba in complex with g247
28% identity, 89% coverage of query (87.4 bits)
6bppA E. Coli msba in complex with lps and inhibitor g092
28% identity, 89% coverage of query (87.4 bits)
6bplA E. Coli msba in complex with lps and inhibitor g907
28% identity, 89% coverage of query (87.4 bits)
FTSE_STRP2 / A0A0H2ZM82 Cell division ATP-binding protein FtsE from Streptococcus pneumoniae serotype 2 (strain D39 / NCTC 7466) (see 3 papers)
FTSE_STRR6 / Q8DQH4 Cell division ATP-binding protein FtsE from Streptococcus pneumoniae (strain ATCC BAA-255 / R6) (see paper)
6z4wA / Q8DQH4 Ftse structure from streptococcus pneumoniae in complex with adp (space group p 1) (see paper)
29% identity, 84% coverage of query (87.4 bits)
6z67B Ftse structure of streptococcus pneumoniae in complex with amppnp at 2.4 a resolution
29% identity, 84% coverage of query (87.4 bits)
7z16I E. Coli c-p lyase bound to phnk/phnl dual abc dimer with amppnp and phnk e171q mutation
27% identity, 88% coverage of query (87.4 bits)
ABCA4_BOVIN / F1MWM0 Retinal-specific phospholipid-transporting ATPase ABCA4; ATP-binding cassette sub-family A member 4; RIM ABC transporter; RIM protein; RmP; Retinal-specific ATP-binding cassette transporter; EC 7.6.2.1 from Bos taurus (Bovine) (see 11 papers)
28% identity, 84% coverage of query (87.0 bits)
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Lawrence Berkeley National Laboratory